• Title/Summary/Keyword: brain structure

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A History of Visualization for Biomedical Information of Meridian (경락경혈 의학정보의 시각화 방법에 대한 역사적 고찰)

  • Lee, Soon-Ho;Lee, In-Seon;Jo, Hee-Jin;Jung, Won-Mo;Lee, Ah-Reum;Kim, Song-Yi;Park, Hi-Joon;Lee, Hye-Jung;Huang, Long-Xiang;Chae, Youn-Byoung
    • Korean Journal of Acupuncture
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    • v.29 no.3
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    • pp.371-384
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    • 2012
  • Objectives : The meridian system is a systematic complex of empirical knowledge, which functions as a basis of acupuncture treatment. In this article, we reviewed the visualization methods of meridian and acupuncture points through the investigation of the characteristics of Diagram of Meridians, Mingtang Diagram, Diagram of Meridians and Collaterals, Bronze Statues and Diagram of Bronze Statue. Methods : We investigated the characteristics of Diagram of Meridians, Mingtang Diagram, Diagram of Meridians and Collaterals, and Bronze Statues. We reviewed the visualization methods of meridian and acupuncture points in those classical Diagrams and analyzed their relationships among them. Results : In order to explain the meridian and acupuncture points easily, ancient people usually used drawings which are named Mingtang Diagram, Diagram of Meridians and Collaterals, by their own characteristics. Owing to their limitations of drawings on the 2 dimensional plane, Chinese people designed the Bronze Statue for Acu-moxibustion and its first invention was invented in Tiansheng age of Song dynasty. For several decades and centuries, these models and drawings were inherited, also reflecting variations of meridian system. As the Bronze Statue has a deficiency in the educational use because of its limitations of mass production, Diagram of Bronze Statue drawn on the 2 dimensional plane was invented. At the beginning of Mingtang Diagram, Diagram of Meridians and Collaterals, Diagram of Bronze Statue and Bronze Statue, their own characteristics were significantly differed with other diagrams and statues. We found that both diagrams and statues were gradually combined with description of the relationship between internal organs and the skeletal structure and the meridian system. Conclusions : Our findings suggest that Diagram of Meridians, Mingtang Diagram, Diagram of Meridians and Collaterals, and Bronze Statues are the basic form of data visualization, one of the infographics. We suggest that ancient Chinese people intend to explain the empirical knowledge using the ancient infographics of meridian system, but have limitations on reflecting theorical or abstractional meaning.

How Does Giftedness Coexist with Autistic Spectrum Disorders (ASD)? Understanding the Cognitive Mechanism of Gifted ASD (영재성과 자폐성장애는 어떻게 공존하는가? 자폐성장애 영재의 인지메카니즘에 대한 이해)

  • Song, Kwang-Han
    • Journal of Gifted/Talented Education
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    • v.21 no.3
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    • pp.595-610
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    • 2011
  • It is hard to understand the coexistence of giftedness and disorder in an individual, but the twice-exceptional is widely recognized now. Gifted autistic spectrum disorder is one of its subtypes in which giftedness exists with autistic spectrum disorder (ASD) simultaneously. Like other constructs including giftedness, the nature of gifted ASD has not been understood in a fundamental and wholistic manner. This paper suggests a cognitive mechanism of gifted ASD based on the integrated model of human abilities(Song, 2009; Song & Porath, 2005), which explains how giftedness coexists with ASD and interacts with each other, producing the characteristics of gifted individuals with ASD. According to the suggested mechanism, the excessive growth of mental spaces in the brain may cause ASD. The over-grown mental spaces result in excessively strong short-term sensory memory and better facility of processing, promoting internal cognitive activities on one hand, but relative lack of cognitive activities in the real world space results in ASD symptoms on the other hand. The cognitive structure of gifted ASD students also contributes to the presentation of giftedness in specific domains. This study suggests that gifted individuals with ASD need to be discouraged from fully engaging in domains they are interested in or the most confident of, rather to be encouraged to invest their giftedness to overcome their ASD symptoms. This study also provides new perspectives on theoretical and educational approaches for gifted ASD.

Development of Forward chaining inference engine SMART-F using Rete Algorithm in the Semantic Web (차세대 웹 환경에서의 Rete Algorithm을 이용한 정방향 추론엔진 SMART - F 개발)

  • Jeong, Kyun-Beom;Hong, June-Seok;Kim, Woo-Ju;Lee, Myung-Jin;Park, Ji-Hyoung;Song, Yong-Uk
    • Journal of Intelligence and Information Systems
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    • v.13 no.3
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    • pp.17-29
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    • 2007
  • Inference engine that performs the brain of software agent in next generation's web with various standards based on standard language of the web, XML has to understand SWRL (Semantic Web Rule Language) that is a language to express the rule in the Semantic Web. In this research, we want to develop a forward inference engine, SMART-F (SeMantic web Agent Reasoning Tools-Forward chaining inference engine) that uses SWRL as a rule express method, and OWL as a fact express method. In the traditional inference field, the Rete algorithm that improves effectiveness of forward rule inference by converting if-then rules to network structure is often used for forward inference. To apply this to the Semantic Web, we analyze the required functions for the SWRL-based forward inference, and design the forward inference algorithm that reflects required functions of next generation's Semantic Web deducted by Rete algorithm. And then, to secure each platform's independence and portability in the ubiquitous environment and overcome the gap of performance, we developed management tool of fact and rule base and forward inference engine. This is compatible with fact and rule base of SMART-B that was developed. So, this maximizes a practical use of knowledge in the next generation's Web environment.

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The Illusion of Determinism and Free Will as a Functional Kinds Term (결정론의 환상과 기능류어로서의 자유의지)

  • Mo, Kiryong
    • Korean Journal of Cognitive Science
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    • v.24 no.3
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    • pp.237-270
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    • 2013
  • Determinism and compatibilism have thought that libertarianism contradicts the scientific view. This paper demonstrates that the hypothesis that free will exists does not cause any problems and contradictions, while maintaining pro-scientific view. Rather, determinism lacks scientific and demonstrative bases. At first, I reject dualistic self by assuming identity theory of the self and physical body & brain. Free will is a functional concept or property that can have multiple realization. Therefore we can recognize whether aliens or robots have free will through observation on their acts. 'Free will' is a functional kinds term like 'digestion'. As we know we have digestive function, we can know that we have free will even before knowing the necessity of its existence by understanding micro structure of human free will. The judgement that an individual has free will function depends on whether it has particular actions. Those actions are controlling and restraining actions in context, predicting future, making elaborate conditional sentences, etc. Real being of free will is the physical occupant of the function that makes those actions. Determinism is based on various kinds of misconceptions and misunderstandings. Determinists often confuse necessity of physical law and determinism. Another decisive misunderstanding is that free will postulates same conditions and different results from the same point of time. However, free will postulates that the two points of time are different. Because determinism is unnecessary redundant hypothesis influenced by religions, according to Ockham's Razor, determinism should be eliminated.

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Computer Vision and Neuro- Net Based Automatic Grading of a Mushroom(Lentinus Edodes L.) (컴퓨터시각과 신경회로망에 의한 표고등급의 자동판정)

  • Hwang, Heon;Lee, Choongho;Han, Joonhyun
    • Journal of Bio-Environment Control
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    • v.3 no.1
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    • pp.42-51
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    • 1994
  • Visual features of a mushromm(Lentinus Edodes L.) are critical in sorting and grading as most agricultural products are. Because of its complex and various visual features, grading and sorting of mushrooms have been done manually by the human expert. Though actions involved in human grading look simple, it decision making underneath the simple action comes from the result of the complex neural processing of visual image. Recently, an artificial neural network has drawn a great attention because of its functional capability as a partial substitute of the human brain. Since most agricultural products are not uniquely defined in its physical properties and do not have a well defined job structure, the neuro -net based computer visual information processing is the promising approach toward the automation in the agricultural field. In this paper, first, the neuro - net based classification of simple geometric primitives were done and the generalization property of the network was tested for degraded primitives. And then the neuro-net based grading system was developed for a mushroom. A computer vision system was utilized for extracting and quantifying the qualitative visual features of sampled mushrooms. The extracted visual features of sampled mushrooms and their corresponding grades were used as input/output pairs for training the neural network. The grading performance of the trained network for the mushrooms graded previously by the expert were also presented.

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Total Intracranial Volume Measurement for Children by Using an Automatized Program (자동화 프로그램을 이용한 아동의 전체두개강내용적 평가)

  • Lee, Jeonghwan;Kim, Ji-Eun;Im, Sungjin;Ju, Gawon;Kim, Siekyeong;Son, Jung-Woo;Shin, Chul-Jin;Lee, Sang-Ick;Ghim, Hei-Rhee
    • Korean Journal of Biological Psychiatry
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    • v.21 no.3
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    • pp.81-86
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    • 2014
  • Objectives Total intracranial volume (TIV) is a major nuisance of neuroimaging research for interindividual differences of brain structure and function. Authors intended to prove the reliability of the atlas scaling factor (ASF) method for TIV estimation in FreeSurfer by comparing it with the results of manual tracing as reference method. Methods The TIVs of 26 normal children and 26 children with attention-deficit hyperactivity disorder (ADHD) were obtained by using FreeSurfer reconstruction and manual tracing with T1-weighted images. Manual tracing performed in every 10th slice of MRI dataset from midline of sagittal plane by one researcher who was blinded from clinical data. Another reseacher performed manual tracing independently for randomly selected 20 dataset to verify interrater reliability. Results The interrater reliability was excellent (intraclass coefficient = 0.91, p < 7.1e-07). There were no significant differences of age and gender distribution between normal and ADHD groups. No significant differences were found between TIVs from ASF method and manual tracing. Strong correlation between TIVs from 2 different methods were shown (r = 0.90, p < 2.2e-16). Conclusions The ASF method for TIV estimation by using FreeSurfer showed good agreement with the reference method. We can use the TIV from ASF method for correction in analysis of structural and functional neuroimaging studies with not only elderly subjects but also children, even with ADHD.

A Study on the Risk of Lightning in Special Structures and its Verification Method (특수 구조물의 낙뢰 위험도와 검증 방안에 관한 연구)

  • Yoo, Jeong Hyun;Kim, Hei Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.6
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    • pp.664-668
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    • 2018
  • Free-standing structures that are especially high are more likely to receive brain attacks caused by lightning. Since special structures are generally part of national industrial structures, lightning strikes mostly cause socio-economic damage. Lightning protection facilities are installed to prevent such lightning damage, but in 2015, support cables on West Sea bridges were hit by lightning, causing a lot of economic damage. Accordingly, the design of a lightning protection system shall establish protective measures after analyzing the risk of debris falling onto the structure. In this thesis, lightning strikes are analyzed directly in relation to the modeling system that operates the actual information collection system for lightning strikes, depending on the location of the tall, free-standing structures, and practical lightning hazard information is provided by a meteorological station. In addition, we propose monitoring and applying a probability correction rate to the calculation of the lightning risk based on the number of lightning strikes directly reaching the ground in order to obtain an effective lightning risk assessment.

Significance of Cerebral Venography in Surgery of Petroclival Meningiomas (추체사대 수막종의 수술과 관련하여 뇌 정맥조영상의 의미)

  • Hwang, Sung-Kyun;Gwak, Ho-Shin;Paek, Sun Ha;Oh, Chang-Wan;Lee, Sang Hyung;Kim, Dong Gyu;Kim, Hyun Jib;Jung, Hee-Won
    • Journal of Korean Neurosurgical Society
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    • v.30 no.10
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    • pp.1200-1209
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    • 2001
  • Objective : A thorough understanding of the related venous structure is mandatory for successful removal of the petroclival meningiomas. This study was planned to investigate the guideline for safe ligation and incision of transverse or sigmoid sinuses and the importance of drainage pattern of vein of $Labb{\acute{e}}$ in surgical removal of petroclival meningiomas. Patients and Methods : The authors reviewed the venogram of the consecutive 37 cases of petroclival meningiomas and retrospectively analyzed their surgical findings. The drainage pattern of confluence of Herophili was classified as Type A(confluent & equal on both sides), Type B(confluent & non-dominant on tumor side), Type C(confluent & dominant on tumor side) and Type D(unilateral drainage only) as these findings gave the information on safe ligation and resection of the sinus. Usefulness of intraoperative test clamping of sinus for safe ligation was also reviewed. The vein of $Labb{\acute{e}}$ was analyzed with respect to its draining point and its collaterals to other superficial veins. Results : Contraindications of the sinus ligation and resection according to the drainage pattern at the confluence of Herophili were Type C(n=10, 27%)and Type D(n=4, 11%). Patients with Type A(n=12, 32%)and Type B(n=11, 30%) were tolerable to sinus ligation ipsilateral to tumor, if the test clamping proved to be safe. Identification of no brain swelling, after intraoperative test clamping of the sinus for more than 30 minutes performed in 7 out of 11 cases, was a reliable indicator of safe sinus ligation. The drainage pattern of the vein of $Labb{\acute{e}}$, especially low-lying type, could predict the possibility of postoperative hemorrhage and infarction. Its drainage into tentorium or superior petrosal sinus, however, made the transtentorial approach impossible, leading to restricted operative field. Conclusion : For a successful removal of the petroclival meningiomas preoperative venogram should be examined carefully. The extent of exposure in a planned approach can be estimated by analyzing the variation of sinuses and the drainage pattern of vein of $Labb{\acute{e}}$.

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Molecular Cloning and mRNA Expression of the Porcine Insulin-responsive Glucose Transporter (GLUT4)

  • Zuo, Jianjun;Dai, Fawen;Feng, Dingyuan;Cao, Qingyun;Ye, Hui;Dong, Zemin;Xia, Weiguang
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.5
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    • pp.640-648
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    • 2010
  • Insulin-responsive glucose transporter 4 (GLUT4) is a member of the glucose transporter family and mainly presents in skeletal muscle and adipose tissue. To clarify the molecular structure of porcine GLUT4, RACE was used to clone its cDNA. Several cDNA clones corresponding to different regions of GLUT4 were obtained by amplifying reverse-transcriptase products of total RNA extracted from Landrace porcine skeletal muscles. Nucleotide sequence analysis of the cDNA clones revealed that porcine GLUT4 cDNA was composed of 2,491 base pairs with a coding region of 509 amino acids. The deduced amino acid sequence was over 90% identical to human, rabbit and cattle GLUT4. The tissue distribution of GLUT4 was also examined by Real-time RT-PCR. The mRNA expression abundance of GLUT4 was heart>liver, skeletal muscle and brain>lung, kidney and intestine. The developmental expression of GLUT4 and insulin receptor (IR) was also examined by Real-time RT-PCR using total RNA extracted from longissimus dorsi (LM), semimembranosus (SM), and semitendinosus (SD) muscle of Landrace at the age of 1, 7, 30, 60 and 90 d. It was shown that there was significant difference in the mRNA expression level of GLUT4 in skeletal muscles of Landrace at different ages (p<0.05). The mRNA expression level of IR also showed significant difference at different ages (p<0.05). The developmental change in the mRNA expression abundance of GLUT4 was similar to that in IR, and both showed a higher level at birth and 30 d than at other ages. However, there was no significant tissue difference in the mRNA expression of GLUT4 or IR (p>0.05). These results showed that the nucleotide sequence of the cDNA clones was highly identical with human, rabbit and cattle GLUT4 and the developmental change of GLUT4 mRNA in skeletal muscles was similar to that of IR, suggesting that porcine GLUT4 might be an insulin-responsive glucose transporter. Moreover, the tissue distribution of GLUT4 mRNA showed that GLUT4 might be an important nutritional transporter in porcine skeletal muscles.

Functional MRI Study on Perceiving Orthographic Structure and Simplified Semantic Pictures (의미론적인 단순화된 그림 및 표의문자를 인지하는 과정에 대한 fMRI 연구)

  • Kim Kyung Hwan;Lee Sung Ki;Song Myung Sung;Kwon Min Jung;Chung Jun Young;Park Hyun Wook;Yoon Hyo Woon
    • Investigative Magnetic Resonance Imaging
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    • v.7 no.2
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    • pp.93-99
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    • 2003
  • The different perceiving patterns of each picture, alphabetic words and Chinese characters, were widely investigated psychophysically. The more precise localisation can be done in terms of brain activity us-ing functional image technique such as PET and fMRI recently, Until now, there was no fMRI study to make direct comparison between perception of single Chinese character and simplified pictures (pictograph). We have made direct comparison of these two components using modern magnetic resonance techniques. We cannot confirm the right hemispheric dominance for perception of single Chinese character and pictographs. These two kinds of perceiving pattern can be underlying different mechanism.

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