• The Journal of Korean Physical Therapy
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• 제13권2호
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• pp.407-420
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• 2001

This article provide information pertaining to recent scientific findings regarding neural and motor control development and the effects of brain damage on that development. Clinical and scientific issues pertaining to perinatal and adult-onset brain damage are discussed. The article is intended to provide the clinician with new information that will assist in patient assessment and the establishment of therapeutic interventions

• 한국수학교육학회지시리즈A:수학교육
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• 제55권3호
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• pp.383-396
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• 2016

This study investigated highschool students' brain waves on functional tasks such as a transition(F task) from equation to graph and the other transition(G task) vice versa. A total of 39 students participated in the study who attended a high school located in Gyunggi province. These students were divided into two groups, HMA and LMA by MASS test revised by Ko, & Yi (2012). The functional tasks for the stroop task to measure EEG were provided from a previous study, Seok(2015). The results indicated two groups on G tasks showed deeper and wider brain waves which demonstrated G tasks were more difficult than F tasks. However, HMA group had an effect of the non-psychological program which had given more chances on G tasks rather than F tasks within Students' Zone of Proximal Development. Also, HMA group's brain waves had more ranges in amplitude and width of waves. These results imply that the characteristics of students' brain waves with math anxiety are consistent to the previous studies.

• 임상간호연구
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• 제22권3호
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• pp.265-275
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• 2016

Purpose: The purpose of this study was to develop an evidence-based guideline for fever management for critically ill adult patients after a brain injury. Methods: Development of the guideline process was done according to the De Novo development Korean Medical Guideline Information Center (KoMGI) and consists of 12 steps. Results: This developed guideline included 3 domains and 19 recommendations. The number of recommendations for each domain was 7 on measuring temperature, 9 on managing fever, and 3 on managing shivering. The level of evidence was as follows: 58% were at level I, and 42% at level II. Of the recommendations, 58% were graded as A, 37% as B, and 5% as C. Conclusion: These findings indicate that this guideline can be used as a guide for nursing in critically ill adult patients with brain injury. This guideline can also contribute to improvements in the quality of nursing care for critically ill adult patients with brain injury.

• 인지과학
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• 제28권4호
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• pp.267-297
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• 2017

뇌의 해부학적 구조에는 개인의 인지적 특성에 대한 많은 정보가 반영된다. 본 연구는 아동과 청소년을 대상으로 생물학적 성숙과 지능의 개인차와 관련한 대뇌의 구조적 변화와 특성을 관찰한 연구들을 중점적으로 개관하였다. 본 연구의 목적은 아동과 청소년의 뇌 구조의 발달 과정을 이해함과 동시에 개인의 지능에 따라 뇌 구조가 발달하는 패턴이 어떠한 차이가 있는지를 알아보는 것이다. 첫 번째 단원에서는 뇌의 구조적 특성에 대한 측정치들(전체 뇌의 크기나 부피, 영역 별 회백질/백질의 부피와 밀도, 피질 두께, 피질 표면적 등)과 부피소-기반 계측법 및 구조적 공분산성 분석 등의 연구 방법들을 설명한다. 두 번째 단원에서는 생물학적 성숙에 따른 뇌 구조의 발달적 변화와 이에 영향을 미치는 변수와 조절 변인들(성별, 정신/발달 장애, 환경 요인, 영역 별 피질의 층 구조)을 설명한다. 세 번째 단원에서는 지능의 두정-전두 통합 이론을 소개하고 뇌 구조 및 뇌의 구조적 공분산성, 기능적 연결성의 발달적 변화가 지능의 개인차에 따라 어떻게 달라지는지에 대한 연구 결과들을 개관한다. 끝으로, 결론 부분에서는 현재까지 이루어진 연구들을 기반으로 하여 후속 연구의 방향과 이 분야 연구의 사회적 가치를 논한다.

• 디지털융복합연구
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• 제17권4호
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• pp.187-194
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• 2019

본 연구는 산업정책 및 기업전략의 개발 및 적용에 활용될 수 있는 브레인 임플란트 산업의 장기 미래 시나리오 모델개발 및 시나리오별 대응전략을 개발하는 것을 연구의 목적으로 삼았다. 뇌과학 산업은 미래 핵심 산업으로 그 가능성에 대하여서는 많은 논의가 있었지만 구체적인 산업육성정책이나 기업전략 분야는 연구가 매우 부족한 실정이다. 이는 이 분야가 아직 산업육성정책이나 기업전략을 작성하기에 필요한 정보가 축적되지 못하였기 때문이다. 이러한 한계를 극복하기 위하여 본 연구에서는 뇌과학산업의 핵심영역으로 많은 불확실성이 존재하는 브레인 임플란트 산업에 대하여 시스템 다이내믹스 모델로 미래 시나리오를 작성하고 이를 기반으로 각각의 시나리오에 적합한 전략을 제시하였다. 따라서 본 연구는 뇌과학산업 육성 정책 입안 및 개별 기업에서의 전략개발에 주요한 자료로 활용될 수 있을 것으로 기대된다. 향후 글로벌 시장 상황이 어느 시나리오로 발전하는 지를 조기에 파악할 수 있는 신호에 관한 연구의 필요성이 제기된다.

• Clinical and Experimental Pediatrics
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• 제52권8호
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• pp.856-861
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• 2009

Cardiopulmonary arrest has long been accepted as an unquestionable definition of death. An advent of cardiopulmonary resuscitation and artificial ventilation along with the development of organ transplantation has prompted the emergence of the concept of brain death. The criteria for brain death are based mainly on the clinical examination of coma, apnea and total loss of brain stem function. Although organ transplantation by donor brain death has increased in Korea over recent years, there is still a substantial shortage of donor organs compared to the demand. Improvement of government policies and changes of social culture for organ donation are needed for the activation of organ transplantation by donor brain death. Pediatricians have an important role for the search of potential donors in cases of brain death and optimal medical care for successful organ transplantation.

• 대한방사성의약품학회지
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• 제7권1호
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• pp.3-10
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• 2021

For successful boron neutron caputre therapy, it is essential to develop a boron drug with a selective accumulation capacity for tumors. In particular, in order to apply boron neutron caputre therapy to brain tumors, drugs with good blood-brain barrier penetration are required. In this study, two low-molecular-weight boron compounds were introduced as brain tumor boron neutron caputre therapy drugs, and their physical and biological efficacy were evaluated. Among them, B2 showed good blood-brain barrier permeability and a high brain/blood ratio. From these results, it is expected that B2 can be used as a useful boron drug for boron neutron caputre therapy in brain tumors.

• 한국초등과학교육학회지:초등과학교육
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• 제33권1호
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• pp.140-161
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• 2014

The purpose of this study was to analyze 181 papers about brain-based learning appeared in domestic scientific journals from 1989 to May of 2012 and suggest application conditions in elementary science education. The results of this study summarizes as follows; First, learning activity suggested by brain-based learning study is mainly explained by working of brain function. Learning activity explained by brain-based learning study are divided into 'learning according to specialized brain function, learning according to brain function integration and learning beyond specialization and integration of hemispheres'. Second, it searched how increased knowledge of brain structure and function affects learning. Analysis from this point of view suggests that brain-based learning study affects learning in many ways especially emotion, creativity and learning motivation. Third, brain-based learning study suggests various possibilities of learning activity reflecting brain plasticity. Plasticity which is one of most important characteristics of brain supports the validity of learning activity as learning disorder treatment and explains the possibility of selective increment of brain function by leaning activity and the need of whole-brain approach to learning activity. Fourth, brain-based learning brought paradigm shifts in education field. It supports learning sophistication on the understanding of student's learning activity, guides learning method that reflects the characteristics of subject and demands reconstruction of curriculum. Fifth, there are many conditions to apply brain-based learning in elementary science education field, learning environment that fits brain-based learning, change of perspectives on teaching and learning of science educators and development of brain-based learning curriculum are needed.

• 생물정신의학
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• 제30권1호
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• pp.1-6
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• 2023

Many psychiatric disorders are associated with brain functional dysfunctions and neuronal degeneration. According to the research so far, enhanced brain plasticity reduces neurodegeneration and recovers neuronal damage. Brain-derived neurotrophic factor (BDNF) is one of the most extensively studied neurotrophins in the mammalian brain that plays major roles in neuronal survival, development, growth, and maintenance of neurons in brain circuits related to emotion and cognitive function. Also, BDNF plays an important role in brain plasticity, influencing dendritic spines in the hippocampus neurogenesis. Changes in neurogenesis and dendritic density can improve psychiatric symptoms and cognitive functions. BDNF has potent effects on brain plasticity through biochemical mechanisms, cellular signal pathways, and epigenetic changes. There are pharmacological and non-pharmacological interventions to increase the expression of BDNF and enhance brain plasticity. Non-pharmacological interventions such as physical exercise, nutritional change, environmental enrichment, and neuromodulation have biological mechanisms that increase the expression of BDNF and brain plasticity. Non-pharmacological interventions are cost-effective and safe ways to improve psychiatric symptoms.

• 한국약용작물학회:학술대회논문집
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• 한국약용작물학회 2008년도 추계학술발표회
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• pp.470-470
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• 2008