• Title/Summary/Keyword: bone age

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The Associated Factors of Bone Mineral Density in Postmenopausal (폐경후에 골밀도의 관련인자 분석)

  • Kang, Jeom-Deok
    • The Journal of Korean Physical Therapy
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    • v.13 no.1
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    • pp.97-105
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    • 2001
  • Objectives: The objective of this study was to investigate the Associated factors of bone mineral density in postmenopausal was measured for 36 normal in the women from July 14.2000 to august 24,2000. Methods: The data were collected from women who visited Physical Examination Center of a Catholic university hospital located in Taegu. Bone mineral density(BMD) of lumbar spine was measured using energy absorptiometry. Results: The bone mineral density of the lumbar spine decreased with aging. The bone mineral density of the lumbar spine increased with number of delivery and number of abortion decreased. The mean bone mineral density of the lumbar spine of postmenopausal women in age less than 50 and 50 ${\sim}$ 59 were 0.79 g/c$m^2$, the lumbar spine of postmenopausal women in age greater than 60 was 0.69 g/c$m^2$. The mean bone mineral density of the lumbar spine of postmenopausal women in mean age 56.1. Conclusions: In the multiple regression of risk factors to bone mineral density(BMD) of lumbar spine were correlated with bone mineral density T-scores(p<0.05). Osteoporosis is a major public health problem among the elderly, demanding effective strategic approach for prevention and treatment.

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Prediction Model for Reduced Bone mass in Women using Individual Characteristics & Life Style Factors (여성의 개인적 특성과 생활양식요인을 이용한 골량감소 예측모형)

  • Lee, Eun-Nam;Lee, Eun-Ok
    • Journal of muscle and joint health
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    • v.5 no.1
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    • pp.83-109
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    • 1998
  • This study was carried out to identify the Important modifiable risk factors for reduced bone mass and to construct prediction model which can classify women with either low or high bone mass. Through the literature review, individual characteristics such as age, body weight, height, education level, family history, age of menarche, postmenopausal period, gravity, parity, menopausal status, and breast feeding period were identified and factors of life style such as past milk consumption, past physical activity, present daily activity, present calcium intake, alcohol intake, cigarette smoking, coffee consumption were identified as influencing factors of reduced bone mass in women. Four hundred and eighty women aged between 28 and 76 who had given measurement bone mineral density by dual energy x-ray absortiometry in lumbar vertebrae and femur from July to October, 1997 at 4 general hospitals in Seoul and Pusan were selected for this study. Women were excluded if they had a history of any chronic illness such as rheumatoid arthritis, diabetes mellitus, hyperthroidism, & gastrointestinal disorder and any medication such as calcium supplements, calcitonin, estrogen, thyroxine, antacids, & corticosteroids known affect bone. As a result of these exclusion criteria, four hundred and seventeen women were used for analysis. Multiple logistic regression model was developed for estimating the likelihood of the presence or absence of reduced bone mass. A SAS procedure was used to estimate risk factor coefficient. The results are as follows For lumbar spine, the variables significant were age, body weight, menopause status, daily activity, past milk consumption, and past physical activity(p<0.01), while for femoral Ward's triangle, age, body weight, level of education, past milk consumption, past physical activity(p<0.001). Past physical activity, present daily activity and past milk consumption are the most powerful modifiable predictors in vertebrae and femur among the predictors. When the model performance was evaluated by comparing the observed outcome with predicted outcome, the model correctly identified 74.1% of persons with reduced bone mass and 84.5% of persons with normal bone mass in the lumbar vertebrae and 82.9% of persons with reduced bone mass and 75.0% of persons with normal bone mass in the femoral Ward's triangle. On the basis of these results, a number of recommendations for the management of reduced bone mass may be made : First, those woman who are classified as high risk group of the reduced bone mass in the prediction model should examine the bone mineral density to further examine the usefulness of this model. Second, the optimal amount of milk consumption and a regular weight bearing exercise in childhood, adolescence, and early adult should be ensured.

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An Epidemiologic Study of Metastatic Bone Tumor (전이성 골종양의 역학적 연구)

  • Kim, Jae-Do;Lee, Duk-Hee;Park, Jeong-Ho;Son, Young-Chan;Hong, Yonng-Gi;Son, Jeong-Hwan
    • The Journal of the Korean bone and joint tumor society
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    • v.1 no.1
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    • pp.38-44
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    • 1995
  • Metastatic bone tumor is the most common bone tumor and 32.5% of all primary malignant tumors are eventually metastasize to bone. Metastatic bone tumor has been more frequently encountered disease in the orthopedic fields due to the greater longevity of life of the patients with primary visceral cancers by major advances in early detection, diagnosis, and surgical/radiotherapeutic/chemotherapeutic treatment of primary and metastatic lesions. Therefore, the epidemiologic data about the incidences and the patterns of bone metastasis is important. We reviewed 417 patients who were diagnosed and treated for metastatic bone tumor at Kosin University Medical Center from 1985 to 1993 to analyse the primary lesion, age and sex distributions, location of bone metastasis, patterns of metastasis according to the primary. The results were as follows : 1. The common origin of bone metastasis were lung(29.5%), stomach(15.3%), breast(11.3%), unknown(7.7%), cervix(5.3%), liver(4.8%) in order of frequency. 2. There were 251 men and 166 women and their mean age was 54.8 years and the peak age incidence was in 6th decades. Most cases(85.3%) were occured beyond 5th decades. 3. The preferred sites of metastatic deposits were spine(64.0%), pelvis(40.5%), rib(38.8%), femur(36.7%), skull(21.1%), humerus(13.9%), scapula(13.0%) in order of frequency. In the spine, thoracic(42.1%), lumbar(39.1%), cervical(13.2%), sacral(5.6%) vertebrae were involved in order of frequency. 4. Multiple bone metastases were more common(73.1%) than single metastasis(26.9%). 5. In the lung cancer, the peak age incidence was 6th decades, and the preferred sites of bone metastasis were spine, pelvis, femur. 6. In the stomach cancer, the peak age incidence was 6th decades, and the preferred sites of bone metastasis were spine, femur, pelvis. 7. In the breast cancer, the peak age incidence was 5th decades, and the preferred sites of bone metastasis were spine, rib, pelvis. 8. In the bone metastasis with unknown primary site, the peak age incidence was 7th decades, the preferred sites of bone metastasis were spine, femur, pelvis, and the common histologic types were adenocarcinoma and squamous cell carcinoma.

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Automatic Bone Age Estimation Based on Carpal-bone Image (Carpal Bone 영상을 이용한 자동 뼈 나이 측정)

  • 박성미;김진철;임옥현;이배호
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.10b
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    • pp.808-810
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    • 2004
  • 왜소증 조기진단을 위한 왼쪽 손의 방사선 영상을 통한 방법은 일반적으로 나이와 성별에 따른 방사선 영상들과 비교하여 의사가 직접 눈으로 비슷한 영상을 찾아 뼈 나이를 추정한다. 하지만 나이, 성별, 민족 등 여러 요인에 따라서 측정결과가 달라질 수 있고 각 나라별로 독자적인 기준이 필요하므로 본 논문에서는 한국인의 Carpal bone 분석과 이에 따른 Computerized Bone Age System을 제안한다. 뼈 나이 측정을 위해 6개의 연골을 측정하고, 분석할 6개의 연골 ROI(Region of Interest)를 찾기 위하여 연골들의 에지를 검출하였다. 영상의 에지를 검출하기 위하여 DoG (Difference of Gaussian) Filtering을 사용하였으며, Carpal Bone을 분석한 뒤 2차원 특징들로 ㅂW 나이 추정에 대한 진단의 정확도를 확인 할 수 있었다.

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A Study on Relations between Obesity and Skeletal Maturity (비만과 골성숙도의 상관성에 대한 연구)

  • Seo, Hui-Yeon;Han, Jae-Kyung;Kim, Yun-Hee
    • The Journal of Pediatrics of Korean Medicine
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    • v.22 no.2
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    • pp.19-35
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    • 2008
  • Objectives : As obese children have been increased, the interest in the impact of obesity on growth also have been increased. This study is to examine relations between obesity and skeletal maturity by analyzing body compositions and bone age. Methods : Subjects were composed of 233 children from 6 years to 17 years of age, without any other diseases related to growth, who visited the department of pediatrics, OO oriental medicine hospital and measured their body composition (body mass index, body fat ratio, fitness score) and bone age. Results : 1. As body mass index was increased, the skeletal maturity significantly was also increased. 2. As the mean of bone maturity was increased, the BMI was increased from the underweight type to the normal type to the overweight type; the bone maturity was increased as the fat ratio was increased from the normal type to the obese type to the excessively obese type; and the bone maturity was higher in the weak, obese type than the normal type when classified according to the Fitness Score. 3. The bone maturity of the overweight group in the BMI classification and excessively obese group in the fat ratio classification significantly were increased. 4. Skeletal maturity significantly was increased in children who developed secondary sexual character. 5. The significance of obesity causing increase of the skeletal maturity was higher in boys than in girls. 6. Only in the case of children without development of secondary sexual character, obesity caused an significant increases in the skeletal maturity. Conclusions : Obesity could cause the increase of skeletal maturity, and the obesity could affect more to the boys than girls and more to the children than teenagers.

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Statistical Observation for Measurement of Bone Mineral Density of the Spine in Korean Women Screening in a Health Clinic (건강진단상 여성골밀도 측정의 통계학적 관찰)

  • Kim, Hee-Seup;Park, Lee-Gap;Lee, Jung-Sook;Lee, Seung-Sub
    • The Journal of the Korean life insurance medical association
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    • v.15
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    • pp.93-98
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    • 1996
  • During the period from January to September 1995, 1.010 Women(premenopausal 466 cases and postmenopausal 544 cases) of employees and family member were observed for bone mineral density of lumbar spine using Dual Energy X-ray Absorptiometry(DEXA) at Medical Department of Korea Life Insurance Co. Ltd. Results obtained were as follows: 1) In premenopausal women 466 cases, the ratio of decreased bone mineral density of lumbar spine according to age groups shows 3rd decade were 5 cases(9.80%) among 51 cases, 4th decade were 31 cases(8.68%) among 357 cases, and 5th decade were 10 cases(17.24%) among 58 cases. 2) In postmenopausal women 544 cases, the ratio of decreased bone mineral density of lumbar spine according to age groups shows 3rd decade were 2 cases(66.67%) among 3 cases, 4th decade were 28 cases(31.11%) among 90 cases, 5th decade were 168 cases(48.70%) among 345 cases, 6th decade were 73 cases(73.0%) among 100 cases, and 7th decade were 4 cases(66.67%) among 6 cases. 3) Bone mineral density begins to decrease with age as early as the 4th decade, even in the premenopausal state. In the 4th decade, premenopausal women exhibit an average 8.68% decrease in bone density. Postmenopausal women in this same age group, however, demonstrate an average bone density decrease of 31.11%.

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Relationship of bony trabecular characteristics and age to bone mass (연령과 골소주 특성의 골량에 대한 연관관계)

  • Choi Dong-Hoon;Song Young-Han;Yoon Young-Nam;Lee Wan;Lee Byung-Do
    • Imaging Science in Dentistry
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    • v.36 no.2
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    • pp.95-101
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    • 2006
  • Purpose : Bony strength is dependent on bone mass and bony structure. So this study was designed to investigate the relationship between the bone mass and bony trabecular characteristics. Subjects and Methods : Study subjects were 51 females (average age 68.6 years) and 20 males (average age 66.4 years). Bone mineral density (BMD, $grams/cm^2$) of proximal femur was measured by a dual energy X-ray absorptiometry (DEXA). Regions of interest (ROIs) were selected from the digitized radiographs of proximal femur. A customized computer program processed morphologic operations (MO) of ROIs. 44 skeletal variables of MO were calculated from ROIs on the Ward's triangle and greater trochanter of femur. WHO BMD classes were predicted by MO variables of the same ROI. Classification and Regression Tree analysis was used for calculating weighted kappa values, sensitivity and specificity of MO. Results : The discriminating factors of morphologic operation were branch point, branch point [per cm sq]. Age also played important role in distinguishing osteoporotic classes. The sensitivity of MO at Ward's triangle and Greater Trochanter was 91.8%, 65.6%, respectively. The specificity of MO was 100% at Ward's triangle and Greater Trochanter. Conclusion : Bony trabecular characteristics obtained using radiological bone morphometric analysis seem to be related to bone mass.

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Bone Mineral Density, with Anthropometric Measurement, and Maternal Factors for Postmenopausal Women in Chungnam (폐경 후 여성들의 골밀도와 신체 측정치 및 모성 요인과의 관련성 연구 -충남 일부 지역을 중심으로-)

  • Park, Mie-Ja
    • The Korean Journal of Food And Nutrition
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    • v.20 no.4
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    • pp.450-459
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    • 2007
  • This study was performed to assess the relationships between bone mineral density(BMD), anthropometric measurements, and maternal factors in postmenopausal women. The anthropometric measurements were taken by a trained practitioner, and the maternal factors of the 85 subjects in Chungnam were acquired by an interview questionaire. The BMDs of the lumbar $spines(L_2-L_4)$, femoral necks(FN), ward's triangles(WT), and trochanters(TR) were measured by dual energy X-ray absorptiometry(DEXA). The BMDs(T-score) for $L_2-L_4$, FN, and WT were 0.996 $g/cm^2$(-1.601), 0.697 $g/cm^2(-1.657)$, and 0.793 $g/cm^2(-1.512)$ respectively, which were assessed as osteopenia by the T-score ; TR was noma1 at 0.718 $g/cm^2(-0.675)$. The 85 subjects in Chungnam were divided into three groups according to their BMD measurements for $L_2-L_4$ and FN, assessed by the T-score. The percentages in the osteoporosis, osteopenia, and normal groups were 32.9%, 42.4, and 24.7%, respectively. The average age was significantly the highest in the osteoporosis group than in the other two osteopenia and normal group(p<0.001). The subjects' BMDs were positively correlated with weight, height, BMI, waist, WHR, OBR and hip circumference, and negatively correlated with the age, duration time after menopause, lactation, the age of last delivery, menarche age, and number of children. The average age at menopause was 48.8. The osteoporosis group's average age at menopause was lower than those of the other groups. However, the BMD of the lumbar spine positively correlated with duration time after menopause and the BMD of the femoral neck with lactation, last delivery, menarch age, number of children. Therefore, researches are needed to find out the effective way to minimize the effect of age and other physiological conditions on the decrease of bone mass density.

Cut-off Values for Diagnosing Kidney Weak Children using Height, Body Weight, Bone Age (신계허약아 진단을 위한 절단값 산정 연구-신장, 체중, 골연령을 기준으로)

  • Kim Tae Hwan;Seo Hae Sun;Doh Tae Yun;Lee Sun Haeng;Lee Jin Yong
    • The Journal of Pediatrics of Korean Medicine
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    • v.37 no.4
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    • pp.1-14
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    • 2023
  • Objectives This study aimed to evaluate the correlation between pediatric weakness scale scores and growth indices. Furthermore, we intended to calculate the cut-off values for diagnosing Kidney Weak Children through growth indices. Methods A total of 193 patients, aged 6 - 12 years, underwent both the pediatric weakness scale and bone age assessment, and the correlations between the pediatric weakness scale and growth indices were analyzed. Moreover, the cut-off values for diagnosing Kidney Weak Children were calculated. Differences in bone age and predicted height between the normal group and Kidney Weak Children, classified according to the calculated cut-off values, were analyzed. Results The weakness of the Shin or kidney system was significantly correlated with the height percentile, weight percentile, differences in current height percentile and mid parental height percentile, differences in predicted height and mid parental height, and differences in bone age and chronological age. When the criteria for diagnosing Kidney Weak Children is set at "height percentile of ≤25% and weight percentile of ≤25%", the sensitivity and specificity of the cut-off value were maximized. The cut-off values for weakness of the Shin or kidney system were 9 in children aged 6 - 9 years and 10 in children aged 10 - 12 years. Conclusions To diagnose Kidney Weak Children, the cut-off values of weakness of the Shin or kidney system were 9 in children aged 6 - 9 years and 10 in children aged 10 - 12 years.

Retrospective Study of Bone Resorption after Maxillary Sinus Bone Graft

  • Moon, Ji-A;Cho, Min-Sung;Jung, Seung-Gon;Kook, Min-Suk;Park, Hong-Ju;Oh, Hee-Kyun
    • Journal of Korean Dental Science
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    • v.4 no.2
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    • pp.59-66
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    • 2011
  • Purpose: This research sought to determine the resorption rate of bone grafted to the maxillary sinus according to the grafted material's type, patient's age, systemic disease, implant size, site of implant placement, and residual ridge height. Materials and Methods: This research targeted 24 patients who had immediate Osstem$^{(R)}$ implant (US Plus$^{(R)}$) placement after bone graft. The panorama was taken before the surgery, after the surgery, and 6 months after the surgery. Vertical height change and resorption rate of the grafted bone were measured with the same X-rays and compared. The influence of the following factors on the grafted bone material's resorption rate was evaluated: grafted material type, patient's age, systemic disease, implant size, site of implant placement, and residual ridge height. Results: Patients in their 40s had $34.0{\pm}21.1%$ resorption rate, which was significantly higher compared to the other age groups (P<0.05). There was no significant relationship between systemic disease and grafted bone resorption. There was no significant relationship between implant size (diameter, length) and grafted bone resorption. There was no significant relationship between the site of implant placement and grafted bone resorption. The ramal bone-grafted site was significantly more resorbed than the ramal bone/Bio-Oss$^{(R)}$-grafted site, maxillary tuberosity bone/Bio-Oss$^{(R)}$-grafted site, and ramal bone/maxillary tuberosity bone/Bio-Oss$^{(R)}$-grafted site (P<0.05). There was no significant difference in the grafted bone resorption rate in the sinus between more than 4 mm and less than 4 mm residual ridge heights. After an average of 6 months, a second surgery was done; given an average follow-up of 1.9 years, the success rate and survival rate of the implant were 96.9% and 98.4%, respectively. Conclusion: These results indicate that the bone resorption rate of grafted bone among patients in their 40s is higher compared to patients in their 50s and over, and that only autogenous bone (ramus) shows higher resorption rate than the mixed graft of autogenous bone and xenogenous graft (Bio-oss) after maxillary sinus graft.