• 한국컴퓨터그래픽스학회논문지
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• 제23권5호
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• pp.19-27
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• 2017

본 논문에서는 두개악안면 CBCT 영상에서 형상제약 정보를 사용한 하악골 자동 분할 방법을 제안한다. 제안방법은 다음의 두 단계로 구생된다. 첫째, MDCT 영상을 사용하여 생성된 통계형상모델을 통해 전역적 형상정보 기반의 하악골 분할을 수행한다. 둘째, 하악골의 지역적 형태 정보 및 밝기값 특징을 고려하여 하악골 분할 개선을 수행한다. 제안 방법의 성능을 평가하기 위해 전문가에 의한 수동 분할 결과를 기준으로 제안방법을 정성적, 정량적으로 평가하였다. 실험결과 큰 곡률로 이루어진 좁은 영역을 포함한 하악골 체부 영역과 위치 변이가 큰 관절구 영역에서 제안방법의 다이스계수(DSC: Dice Similarity Coefficient)는 각각 95.64%, 90.97%를 보였다.

• 여성건강간호학회지
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• 제9권4호
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• pp.379-389
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• 2003

Purpose: To identify the type of disease-related stress experienced by women who received mastectomy for breast cancer using Q methodology. Method: Q sample included 30 statements obtained from literature and interviews with women with mastectomy. P sample consisted of 22 patients with mastectomy. The data were collected from November to December 2002 and analyzed using QUANL program. Result : Four types of disease-related stress experienced by women with mastectomy were found. Type 1 was manifested for a short duration following surgery and characterized by lowered self-esteem, feelings of emptiness and depression because of impaired body image. Type 2 was characterized by declined physical strength, resulting in frequent fatigue in the daily life and less intimate relationship with spouse. Type 3 was manifested by perfectionists with strong sense of self-pride who received or considered breast reconstruction surgery. Type 4 was reported by those who had long period of post-surgery. This type reported a strong sense of discomfort for wearing an artificial breast but didn't show any intention of trying breast reconstruction surgery. Conclusion: Women with mastectomy were found to experience different type of disease-related distress. Therefore, nurses should assess the type of stress the patient experiences following a mastectomy to provide appropriate nursing care.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.1677-1684
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• 2016

Background: Among the factors reported to determine the quality of life of breast cancer patients are socio-demographic background, clinical stage, type of treatment received, and the duration since diagnosis. Objective: The objective of this study was to determine the quality of life (QOL) scores among breast cancer patients at a Malaysian public hospital. Materials and Methods: This cross-sectional study of breast cancer patients was conducted between March to June 2013. QOL scores were determined using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30) and its breast cancer supplementary measure (QLQ-BR23). Both the QLQ-C30 and QLQ-BR23 assess items from functional and symptom scales. The QLQ-C30 in addition also measures the Global Health Status (GHS). Systematic random sampling was used to recruit patients. Results: 223 breast cancer patients were recruited with a response rate of 92.1%. The mean age of the patients was 52.4 years (95% CI = 51.0, 53.7, SD=10.3). Majority of respondents are Malays (60.5%), followed by Chinese (19.3%), Indians (18.4%), and others (1.8%). More than 50% of respondents are at stage III and stage IV of malignancy. The mean Global Health Status was 65.7 (SD = 21.4). From the QLQ-C30, the mean score in the functioning scale was highest for 'cognitive functioning' (84.1, SD=18.0), while the mean score in the symptom scale was highest for 'financial difficulties' (40.1, SD=31.6). From the QLQ-BR23, the mean score for functioning scale was highest for 'body image' (80.0, SD=24.6) while the mean score in the symptom scale was highest for 'upset by hair loss' (36.2, SD=29.4). Two significant predictors for Global Health Status were age and employment. The predictors explained 10.6% of the variation of global health status ($R^2=0.106$). Conclusions: Age and employment were found to be significant predictors for Global Health Status (GHS). The Quality of Life among breast cancer patients reflected by the GHS improves as age and employment increases.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2241-2247
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• 2012

Objective: This qualitative study retrospectively examined the experience and psychological impact of contralateral prophylactic mastectomy (CPM) among Southern Chinese females with unilateral breast cancer history who underwent BRCA1/2 genetic testing. Limited knowledge is available on this topic especially among Asians; therefore, the aim of this study was to acquire insight from Chinese females' subjective perspectives. Methods: A total of 12 semi-structured in-depth interviews, with 11 female BRCA1/BRCA 2 mutated gene carriers and 1 non-carrier with a history of one-sided breast cancer and genetic testing performed by the Hong Kong Hereditary Breast Cancer Family Registry, who subsequently underwent CPM, were assessed using thematic analysis and a Stage Conceptual Model. Breast cancer history, procedures conducted, cosmetic satisfaction, pain, body image and sexuality issues, and cancer risk perception were discussed. Retrieval of medical records using a prospective database was also performed. Results: All participants opted for prophylaxis due to their reservations concerning the efficacy of surveillance and worries of recurrent breast cancer risk. Most participants were satisfied with the overall results and their decision. One-fourth expressed different extents of regrets. Psychological relief and decreased breast cancer risk were stated as major benefits. Spouses' reactions and support were crucial for post-surgery sexual satisfaction and long-term adjustment. Conclusions: Our findings indicate that thorough education on cancer risk and realistic expectations of surgery outcomes are crucial for positive adjustment after CPM. Appropriate genetic counseling and pre-and post-surgery psychological counseling were necessary. This study adds valuable contextual insights into the experiences of living with breast cancer fear and the importance of involving spouses when counseling these patients.

• 대한한의학회지
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• 제22권3호
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• pp.105-118
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• 2001

Objectives : The prescription of Semyung-Gangji-tang, designed for the treatment of hyperlipidemia and atherosclerosis, consists of herbs good for treating blood stasis and phlegm stagnancy. It invigorates the liver, kidneys and spleen. Its medical nature is not too cold or too hot and increases human vital energy. The purpose of this study is to examine the curative effects of Semyung-Gangji-tang on atherosclerosis in hyperlipidemic rabbits. Methods : Twenty-four male NZW rabbits, around 2kg of body weight, were divided into 4 groups. Group I served as the normal group. Group II served as the atherogenic model group, fed a 1 % cholesterol diet for 8 weeks and sacrificed. Group III served as the atherogenic control group, fed with a 1 % cholesterol diet for 8 weeks and with a normal diet for the next 4 weeks. Group IV served as the treatment group treated the same as the control group and medicated with Semyung-Gangji-tang for the last 4 weeks. Three animals of group I and six animals of group n were sacrificed at 8 weeks. Five animals of group I , five animals of group III and IV were sacrificed at 12 weeks. Pathological examinations and image analysis were performed on the collected tissue samples. Results : The percentage of lipid deposition area of thoracic aortas of group IV($41.74{\pm}8.93%$) at 12 weeks was decreased compared with the group III ($71.30{\pm}12.74%$) at 12 weeks, but a statistical difference was not observed. The percentage of group IV at 12 weeks was significantly decreased (P<0.05) compared with the group n ($76.41{\pm}7.43%$) at 8 weeks. Histopathologically, advanced atheromas with calcification of aortic arches were observed in all animals of the control group at 12 weeks, but were observed in 2 animals of the treatment group at 12 weeks. Histopathologically, atheromas with calcification of thoracic aortas were observed with major atherogenic lesions in control group at 12 weeks, but simple fibro-fatty streaks were observed major atherogenic lesions in treatment group at 12 weeks. Conclusions : These results indicate that Semyung-Gangji-tang has antiatherogenic effects on experimentally induced atherosclerosis in rabbits.

• 한국콘텐츠학회논문지
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• 제16권4호
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• pp.544-554
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• 2016

본 연구의 목적은 여대생의 체중조절에 대한 주관성을 확인하고자 Q 방법론을 적용하여 주관적, 해석적 접근을 함으로써 여대생의 체중조절에 대한 구조적 유형과 유형별 특성을 비교분석하고자 시도하였다. 연구대상자는 여대생 39명을 P 표본으로 하여 선정된 41개의 Q 표본을 강제 분류하도록 한 결과 3가지 유형이 도출되었다. 첫 번째, '강박적 체중조절을 시도하는 부정적 체형인식형', 두 번째, '지속적인 체중조절을 통한 건강관리 추구형', 세 번째, '체중조절의 자기통제가 가능한 자아확신형'으로 명명하였다. 본 연구 결과 3가지 유형 간의 구조적인 차이점이 발견되었고, 유형에 따른 특성에 기초하여 바람직하고 올바른 체중조절 행동을 위한 기초자료로 활용할 수 있을 것이다.

• Journal of Acupuncture Research
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• 제20권3호
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• pp.86-103
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• 2003

Objective : Recently, many studies have showed the evidences of the effect of the acupunture treatment through scientific methods. One of these methods is functional MRI. We performed electro-acupunture on Sp6 and observed the changes of brain activation using fMRI. Methods : To see the effect of electro-acupunture stimulation on Sp6, the experiment was carried out on 12 healthy volunteers, using the gradient echo sequence with the 3.0T whole-body MRI system(ISOL). After the needle insertion on right Sp6, 2Hz of electric stimulation was given for 30 seconds, repeated five times, with 30 seconds' intervals. The Image analysis including motion correction, talairach transformation, and smoothing was done with SPM99. Results : 1. Group averaged brain activation induced by bilateral eletro-acupunture stimulation on Sp6 activates Brodman Area 3, 7, 13. 2. Group averaged brain deactivation induced by bilateral eletro-acupunture stimulation on Sp6 activates Brodman Area 6, 38, 47. 3. Group averaged brain activation induced by unilateral(right side) eletro-acupunture stimulation on Sp6 activates Brodman Area 5, 6, 13, 17, 18, 19, 31, 38, 40 ptoms, back pain(32.5%) was the 4. Group averaged brain deactivation induced by unilateral(right side) eletro-acupunture stimulation on Sp6 activates Brodman Area 3, 4, 18, 21, 36, 38, 39. 5. Brain region activated by motor stimulation activates Brodman Area 3, 4, 6, 18, 19.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2007년도 추계종합학술대회
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• pp.901-904
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• 2007

오늘날 많은 의료영역에서 각종 영상 장치를 이용함으로 절개 과정 없이 인체 내부 장기를 가시화함으로 질병의 유무와 진행 상태 등을 관찰할 수 있게 된다. 이러한 장치의 한가지로 초음파 진단장치는 다른 장치에 비해 장비의 가격이 저렴하고 크기가 소형이라 이동 장치가 가능하고 특히 인체에 해를 주지 않고 장시간에 걸쳐 인체 내부를 실시간 관찰할 수 있게 해 줌으로 심장이나 태아의 운동 등을 관찰하는데 유용하게 사용된다. 또한 초음파 영상을 이용하여 각종 내과적 질환을 비관혈적 방법으로 관찰하고 인체 내 연조직 부분의 질병을 진단하는 수단으로 자주 이용 되고 있다. 이러한 초음파 진단장치는 펄스발생기를 통하여 발생된 초음파 펄스를 인체에 조사함으로 서로 다른 매질 사이의 경계면에서 발생하는 반사파와 각 매질내의 입자들에 의해 산란되는 산란파를 통하여 이루어진다. 이 때 평탄한 조직에 발생하는 반사파와 불규칙한 영역에 발생하는 산란파 간의 간섭으로 초음파 영상에는 여러 가지 잡음 특성들이 첨가되게 된다. 이에 본 논문에서는 초음파 태아 영상을 중심으로 그 특성을 조사 처리함으로 보다 개선된 화질의 초음파 영상을 얻고 이로부터 유효한 영역을 효과적으로 추출하고자 한다.

• 방송공학회논문지
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• 제15권5호
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• pp.607-616
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• 2010

현재까지 제안된 3차원 시각피로 측정 방법은 측정의 타당도가 결여되어 있고 시각피로의 복합적인 특성을 제대로 파악해 내지 못 하는 단점이 있다. 본 연구의 목적은 3차원 시각피로의 구성요인을 분석하고 안정적으로 타당하게 주관적인 시각피로를 측정하는 방법을 제안하는 것이다. 연구결과는 다음과 같이 요약된다. 첫째, 시각피로가 네 개의 독립적인 하위요인(시각적 스트레스, 안구 통증, 신체 통증, 상 흐림 요인)으로 구성되어 있음을 규명하였고, 둘째, 네 개의 요인으로 구성되어 있는 3차원 시각피로를 측정할 수 있는 29개의 문항을 개발하였으며, 셋째, 시각피로에 영향을 미칠 것으로 기대되는 시청시간과 양안시차의 조작이 개발된 측정 방법을 이용하여 측정된 시각피로에 실제로 영향을 미침을 확인하였다. 이와 같은 결과는 본 연구에서 제안하는 시각피로 측정 방법이 3차원 시각피로를 타당하게 측정함을 시사한다.

• 한국정보과학회논문지:소프트웨어및응용
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• 제32권5호
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• pp.449-460
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• 2005

본 논문에서는 고정된 카메라로부터 획득된 색상 비디오 프레임에서 조명변화와 겹침으로 인한 왜곡에 강건하게 다수의 사람을 추적하는 방법을 제안한다. 조명변화에 따른 외형변화의 문제점을 해결하기 위하여 시간 비종속적인 본래(intrinsic) 영상을 이용하여 프레임에 존재하는 조명을 제거하며, 매 프레임마다 조명 영상을 적응적으로 갱신한다. 카메라 내에서 사람을 추적하기 위해 색상정보를 포함하는 계충적 사람모델을 사용함으로써 겹침의 문제를 해결한다. 추적된 사람모델은 사람모델 리스트에 저장되어 해당되는 사람이 카메라에서 사라진 후에도 일정 기간 보존됨으로써, 재등장한 사람의 정보를 복원할 수 있다. 본 논문에서 제안하는 적응적 모델기반 방법은 실내${\cdot}$외 영상을 대상으로 여러 시나리오로 실험되어, 조명변화로 왜곡된 사람의 색상정보를 옳게 보정하였을 뿐만 아니라 사람들이 겹치거나 헤어진 후에도 성공적으로 추적하였음을 확인하였다.