• 한방안이비인후피부과학회지
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• 제22권2호
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• pp.39-49
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• 2009

Objective : Phyllostachyos Folium (PF) has been used to treat patients with febrile disease consuming the body fluids marked by fever with restlessness, thirst etc. In the theory of herbology, PF can clear away heat and promote the production of the body fluids, relieve restlessness. Recently PF is known to have anti-bacterial, anti-oxidantic effects. Methods : The present study was carried out to investigate the effects of PF on solid tumor in mice in terms of immune-potentiating and direct cytotoxic action of PF in vitro and vivo study. The present author investigated thymocyte and splenocyte proliferation to confirm immune-potentiating activity of PF and also investigated tumor/body weight ratio and survival rates in tumor bearing mice. Result : In this study, administration of PF decreased tumor/body weight ratio significantly, and prolonged survival duration compared to non-treated control. In addition, treatment with PF suppressed proliferation rate of Sarcoma 180 (S-180) cells significantly, and elevated proliferation rates of thymocytes isolated from normal mice. These results were co-related with in vivo study. Conclusion : In conclusion, these results suggest that PF is useful to treat patient with solid tumor, because PF has direct toxic action for tumor cell and immune -potentiating action for T cells. Further study will need to elucidate exact mechanisms related in anti-cancer action of PF.

• 한국전산유체공학회지
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• 제18권4호
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• pp.9-16
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• 2013

Cavitation on an axi-symmetric hemispherical head-form body was studied using an Reynolds-averaged Navier-Stokes equations solver based on a cell-centered finite volume method. To consider compressibility effects on the vapor phase and cavity interface, a pressure-based compressible flow CFD code was developed. To validate the developed CFD code, cavitating flow around the hemispherical head-form body was simulated using pressure-based incompressible and compressible CFD codes and validated against existing experimental data in the three-way comparison. The cavity shedding behavior, length of re-entrant jet, drag history, and Strouhal number of the hemispherical head-form body were compared between two CFD codes. The results, in this paper, suggested that the computations of cavitating flow with compressibility effects improve the description of cavity dynamics.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 12th Asian Congress of Fluid Mechanics
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• pp.55.4-55.4
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• 2008

• 한국전산유체공학회지
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• 제7권2호
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• pp.8-16
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• 2002

A numerical study on the use of the momentum interpolation method for flows with a large body force is presented. The inherent problems of the momentum interpolation method are discussed first. The origins of problems of the momentum interpolation methods are the validity of linear assumptions employed for the evaluation of the cell-face velocities, the enforcement of mass conservation for the cell-centered velocities and the specification of pressure and pressure correction at the boundary. Numerical experiments are performed for a typical flow involving a large body force. The numerical results are compared with those by the staggered grid method. The fact that the momentum interpolation method may result in physically unrealistic solutions is demonstrated. Numerical experiments changing the numerical grid have shown that a simple way of removing the physically unrealistic solution is a proper grid refinement where there is a large pressure gradient. An effective way of specifying the pressure and pressure correction at the boundary by a local mass conservation near the boundary is proposed, and it is shown that this method can effectively remove the inherent problem of the specification of pressure and pressure correction at the boundary when one uses the momentum interpolation method.

• 한국전산유체공학회지
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• 제9권1호
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• pp.41-47
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• 2004

A successful store separation analysis tool, MSAP(Multi-body Separation Analysis Program) has been applied to F/A-18C/JDAM CFD Challenge Ⅱ. The challenge was devised to challenge CFD community to use CFD methodologies to predict and match the trajectory of a JDAM MK-84 separating from F/A-l8C. Trajectory simulations for two flight conditions were performed. Comparison between computed and measured flight trajectories for both conditions shows a good agreement.

• 한국전산유체공학회지
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• 제8권4호
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• pp.1-5
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• 2003

A Thin-layer Wavier-Stokes equations are applied for the hypersonic flow over blunt bodies with applications to laminar as well as turbulent flows. The equations are expressed in the forms of flux-vector splitting and explicit algorithm. The upwind schemes of Steger-Warming and Van Leer are investigated to predict accurately the heating loads along the surface of the body. A mixed scheme has been presented for the differencing the convective terms and the mixed scheme is found to be less dissipative producing accurate solutions.

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2002년도 동계연구발표회 논문개요집
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• pp.88-89
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• 2002

Studies on drug delivery using nano-size particles of magnetic fluid and hyperthermia have been performed by some researchers [1] because interests in human health increased according to industry development. However, there are few studies on systems which can accurately control delivery of the magnetic fluids to a diseased part of body [2]. In this study, Cu-added magnetic ferrofluid was prepared and the external magnetic field system was designed for drug localization.

• 한국자기학회지
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• 제11권6호
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• pp.245-249
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• 2001

자성유체의 자연대류현상은 중력 및 부력과 함께 자기체적력이 존재하기 때문에 보통의 뉴턴유체와는 다른 양상을 보인다. 본 연구에서는 자장이 자성유체(W-40)의 자연대류에 미치는 영향으로, 이중원관에 있어서 인가자장의 방향과 세기에 따라 자연대류 현상의 변화 및 전열 유동 특성을 실험적으로 해석 연구하고자 한다. 해석모델의 고온 및 저온벽면의 온도는 $25^{\circ}C$와 2$0^{\circ}C$로 설정하였다. 그 결과 자성유체의 자연대류현상은 외부자장에 의해 제어될 수 있다.

• 한국전산유체공학회지
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• 제10권3호
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• pp.27-35
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• 2005

A design optimization of hypersonic flight vehicle has been studied by using upwind Navier-Stokes method and numerical optimization method. CFD method is linked to numerical optimization method by using a Bezier curve and a design optimization of blunt nose hypersonic flight vehicle has been studied. Heat transfer coefficient and drag coefficient are selected as objective functions or design constraints. The Bezier curve-based shape function was applied to blunt body shape.

• 한국전산유체공학회지
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• 제13권3호
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• pp.44-50
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• 2008

The present study is carried out in order to investigate the effect of the periodic acceleration in the stenosed and bifurcated blood vessels. The blood flow and wall shear stress are changed under body movement or acceleration variation. Numerical studies are performed for various periodic acceleration phase angles, bifurcation angles and section area ratios of inlet and outlet. It is found that blood flow and wall shear stress are changed about ${\pm}20%$ and ${\pm}24%$ as acceleration phase angle variation with the same periodic frequency. also wall shear stress and blood flow rate are decreased as bifurcation angle increased.