• Journal of the Korean Institute of Oriental Medical Informatics
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• 제11권2호
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• pp.1-13
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• 2005

Objectives To research oriental medical treatments for diabetic nephropathy by literature study Methods We reviewed oriental medical book concerning the diabetic nephropathy. Results & Conclusions 1. The diabetic nephropathy has relation to edema, dizziness, exhaustion of strenght, obstruction and rejection among the transformations of emaciation and thirst. 2. The causes of diabetic nephropathy are dry heat caused congenital defect, mental depression and greasy diet damages liquid nutrients and thereafter Gi and Yang deficiency produces blood stagnation, dampness and phlegm-turbidity. 3. The medical treatments are invigorating Gi, promoting blood flow to remove blood stasis and removing dampness through diuresis. The frequently used herb are Radix Astragali, Poria, Fructus Corni, Rhizoma Dioscoreae, Radix Salviae Miltiorrhizae, etc. and Dansam is meanigfull of all herbs for invigorating blood and dispelling blood stagnation.

• Nutrition Research and Practice
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• 제1권4호
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• pp.335-340
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• 2007

The purpose of the present study was to examine the relation of total antioxidant status (TAS) to metabolic risk factors in Korean adults. Anthropometric measures, blood pressure, serum lipids and fasting glucose were determined in 406 men and women. TAS was measured by using commercially available Randox kit. Serum TAS was significantly positively correlated with body weight (p=0.004), body mass index (BMI) (p=0.033), waist circumference (p=0.017), total cholesterol (p=0.038) and triglyceride (TG) (p<0.001). The mean TAS of hypertriglyceridemic subjects (TG ${\geq}$150 mg/dl) was significantly higher than that of subjects whose TG was lower than 150 mg/dl (p=0.001). When central obesity, TG, high density lipoprotein cholesterol, fasting glucose and blood pressure were considered as metabolic risk factors, TAS was shown to be elevated with increased number of metabolic risk factors (p=0.004). The positive association between TAS and a number of metabolic risk factors suggests that increased TAS may not always indicate one's healthier condition. In order to help understand TAS as a marker of total antioxidant capacity in humans with various metabolic conditions, it is needed to clarify the factors affecting TAS in relation to changes in metabolic risk factors.

• Journal of Preventive Medicine and Public Health
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• 제24권2호
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• pp.161-170
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• 1991

The purpose of this study is to find the tracking of blood pressure in primary school-age children. A follow-up study was conducted from 1986 to 1990 on 330 first grade children attending primary schools in Kangwha County, Kyungki-Do. Basically we employed a linear regression model with random coefficients to figure out the relation between blood pressure changes and initial blood pressure. We obtained the following results ; 1. The mean blood pressures were increased grade went up in both sexs and were generally higher in female than male except for the systolic blood pressure at first grade. The size of difference was about 0.8 mmHg in mean systolic blood pressure and 1.5 mmHg in mean diastolic blood pressure. 2. The average annual increasing rates of systolic blood pressure were 2.5 mmHg in male and 3.1 mmHg in female respectively. For the diastolic blood pressure IV the average annual increasing rates were observed to be 3.0 mmHg in male and 2.9 mmHg in female respectively. Increasing rate of systolic blood pressure was significantly higher in female than male. 3. The adjusted regression coefficient of systolic blood pressure change on initial value was -0.11 in male and -0.13 in female and that coefficient of diastolic blood pressure change on initial value was -0.01 in male and -0.11 in female. This result shows that children with higher initial blood pressure do not pick up their blood pressure faster than others with lower initial blood pressure. There is no evidence of tracking of blood pressure in children. It is essential to find the earliest age having the tracking of blood pressure and we leave it for the further study.

• Journal of Korean Medical classics
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• 제28권1호
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• pp.143-150
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• 2015

Objectives : This study aim to find out the reason why perspiration related with the Heart in Korean Medicine. Results : Perspiration is closely connected with the Heart because sweat is a kind of ultrafiltrate of the blood and the Heart conducts blood. In order to perspire, it is necessary to increase blood flow to capillary surrounding sweat glands. The Heart plays an important role in increasing blood flow to capillary surrounding sweat glands. Perspiration controls the body temperature. It must be increase the blood flow to skin in order that down the high body temperature. The Heart plays an important role in increasing blood flow. Conclusions : Perspiration is closely connected with the Heart because sweat is a kind of ultrafiltrate of the blood and there are plenty capillary surround sweat gland. The Heart controls the blood flow to skin in order to regulate of body temperature.

• Proceedings of the KSCN Conference
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• 대한지역사회영양학회 2000년도 추계학술대회:통일한국을 대비한 영양감시체계 개발
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• pp.87-87
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• 2000

• Journal of Korean society of Dental Hygiene
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• 제4권1호
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• pp.31-48
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• 2004

Dental caries taking place with milk teeth affects eruption of permanent teeth adversely, and thus, it is very important to prevent dental caries from taking place with a child in maintaining his/her physical, mental and emotional health. In this study as conducted to obtain basic data to be required for development of a program for letting preschool children form a habitual life for oral health and right dietary life, a total 172 children aged 5 years and 6 years were selected from children who lived in Hwasung-si, Kyunggi-do and attended preschools (childrens houses) located there with the consent of their guardians. Then, the weight length index (WLI) and blood components of each child were analyzed, and each relation between the weight length index (WLI) and dental caries of milk teeth and between blood components and dental caries of milk teeth was comparatively examined, and thereby, the following results were obtained. When the dmf rate of each group according to the obesity was examined, it was found to be 87.50% in the under-weight group, 71.20% in the normal weight group and 83.87% in the overweight group. And when the dmft rate of each group was examined, it was found to be 48.43% in the under-weight group, 37.10% in the normal weight group and 47.17% in the overweight group. Also, when the dmft index of each group was examined, it was found to be 3.9 in the under-weight group, 3.0 in the normal weight group and 3.8 in the overweight group. That is to say, the under-weight group and the overweight group having an abnormal weight were found to be higher in all of the dmf rate, the dmft rate and the dmft index than the normal weight group. It could be, therefore, known that normal weight should be maintained in order to prevent dental caries of milk teeth. And, it is thought that a right dietary life habit ensuring intake of balanced nutrients should be formed for maintenance of a normal weight. As a result of examining the relation between nutrient components in blood and dental caries of milk teeth, in the case of children with no dental caries, inorganic nutrient components of blood had a tendency to be a little higher, but no statistical significance was observed therein. Meanwhile, it was found that there was a relation between blood type and the dmft index.

• Journal of Nutrition and Health
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• 제15권3호
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• pp.171-180
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• 1982

The nutritional survey and blood sampling was conducted from May 23 to 27, 1971, in order to investigate the state of the nutritional intake in relation to blood contents of rural women. This survey covered a total of 47 women residing in Youngam-gun, Cholla-namdo, Korea. The daily diet of these subjects was observed by 24-hour recall method and weighing method for 3 days and hemoglobin (Hb), hematocrit(Hct), mean corpuscular hemoglobin concentration (MCHC), serum protein, serum albumin, A/G ratio, serum iron, total iron binding capacity (TIBC), transferrin saturation (TS), serum cholesterol and blood specific gravity (SG) were measured. The results were summarized as follows ; The rate of intake of vegetable foods was high, especially cereals, and that of animal foods was low, especially eggs and milk and milk products. The daily intake of niacin was sufficient, and the intakes of energy and iron were also tend to be adequate. On the contrary, the intakes of vitamin A, $B_2$ and C, calcium and protein were insufficient. The mean red blood cell number was $410.8{\pm}26.4{\times}10^{4}/mm^{3},$ the mean values of Hb, Hct and MCHC were $12.5{\pm}0.9gm%$, $37.5{\pm}2.4%$ and $33.2{\pm}0.5%$ thus the anemic prevalences were 21.3%, 12.8% and 93.6% comparing with the anemic criteria of WHO. The levels of serum protein and serum albumin were $7.1{\pm}0.4gm\;%$ and $4.3{\pm}0.3gm\;%$so the A/G ratio was indicated $1.6{\pm}0.2.$. The levels of serum iron and TIBC were $91.9{\pm}27.5{\mu}g/100ml and $297.5{\pm}31.4{\mu}g/100ml,$ so TS was calculated $31.2{\pm}9.7\;%$. The mean value of SG was $1.044{\pm}0.002,$ and the level of serum cholesterol was $164.3{\pm}25.4mg/dl$. In the relation between each of bloood content, Hb showed positive correlation not only with Hct but also protein at the level of significance of 1 per cent and 5 per cent, and protein also showed a positive correlation with serum cholesterol at the 1 per cent level of significance. In the relation between the nutrient intake and blood contents, vitamin C intake showed a positive correlation with Hb, serum protein and serum iron at the level of significance of 1 per cent, iron intake also showed a positive correlation with serum iron and serum cholesterol at the same significant level, and protein intake showed a positive correlation with serum iron at the at the level of significance of 5 per cent.

• Journal of Korean Medical classics
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• 제30권3호
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• pp.109-131
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• 2017

Objectives : The purpose of this paper is to study the origin, mechanism, category of Chest bind with static blood(血結胸), the relation to the syndrome of Heat entering the blood chamber(熱入血室證), and the comparison with Chest bind(結胸). Methods : Sikuquanshu(四庫全書), a comprehensive range of medical books, and Shanghanlun(傷寒論) annotation books were searched by 'Chest bind with static blood' keyword and analyzed. Results & Conclusions : 1. The syndrome of Chest bind with static blood is first brought up by ZhuGong(朱肱) and it can be derived from the syndrome of Heat entering the blood chamber or can be shown in upper middle lower energizer Stagnated Blood Syndrome(上中下焦蓄血證, SBC). Ever since the publication of Shanghanquanshengji(傷寒全生集), its category was expanded and prescriptions for the SBC were used. 2. In comparison, the cause of Chest bind with static blood is associated with blood heat(血熱), largely connected with blood, mental illness appeared, lesions are usually chest and sides, and the cause of Chest bind is associated with intermingled water heat (水熱) or phlegm heat(痰熱), not connected with blood, mental illness not appeared, lesions are from the beneath the heart to lower abdomen. 3. The syndrome of Chest bind with static blood derived from the syndrome of Heat entering the blood chamber can appear along side with the Liver Meridian associated with blood chamber or appear in chest, the syndrome appeared in upper energizer SBC can be shown in the chest due to gravity, the one appeared in middle energizer SBC can be shown in the chest due to the same level, the one appeared in lower energizer SBC can be shown in the chest due to the constitutional predisposition of YangQi(陽氣) uprise.

• Journal of Nutrition and Health
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• 제46권3호
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• pp.226-238
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• 2013

Omega-3 polyunsaturated fatty acids are essential fatty acids because humans cannot synthesize them de novo and must obtain them in their diet. Fish and fish oil are rich sources of omega-3 fatty acids, including eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Significant evidence of the beneficial role of dietary intake of omega-3 fatty acids in blood flow has been reported and putative mechanisms for improvement of blood flow include anti-thrombotic effects, lowered blood pressure, improved endothelial function, and anti-atherogenic effects. Edible oils containing omega-3 fatty acids were registered as functional ingredients in the Korea Health Functional Food Code. Although omega-3 fatty acids have been evaluated by the Korea Food and Drug Administration (KFDA) based on scientific evidence, periodic re-evaluation may be needed because emerging data related to omega-3 fatty acids have accumulated. Therefore, in this study, we re-evaluated scientific evidence for the effect of omega-3 fatty acids as a functional ingredient in health functional food on improvement of blood flow. A comprehensive literature search was conducted for collection of relevant human studies using the Medline and Cochrane, KISS, and IBIDS databases for the years 1955-2012. Search keywords were used by combination of terms related to omega-3 fatty acids and blood flow. The search was limited to human studies published in Korean, English, and Japanese. Using the KFDA's evidence based evaluation system for scientific evaluation of health claims, 112 human studies were identified and reviewed in order to evaluate the strength of the evidence supporting a relation between omega-3 fatty acids and blood flow. Among 112 studies, significant effects on improvement of blood flow were reported in 84 studies and the daily intake amount was ranged from 0.1 to 15 g. According to this methodology of systematic review, we concluded that there was possible evidence to support a relation between omega-3 fatty acid intake and blood flow. However, because inconsistent results have recently been reported, future studies should be monitored.

• Korean Journal of Community Nutrition
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• 제10권4호
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• pp.493-500
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• 2005

There is some evidence that soy isoflavone has beneficial effects on the concentration of blood lipids. In this study, we investigated habitual isoflavone intake levels and the relation among dietary isoflavone intake, blood pressure, and blood lipids of adult men (n = 149) and women (n = 205). Anthropometric measurements including blood pressure, dietary in-take assessment using 24-hour recall method, and biochemical assessment using blood were conducted. The average age, height, weight, and BMI were 54.7 years, 168.5 cm, 67.3 kg, and 24.5 $kg/m^2$ for men and 53.9 years, 153.8 cm, 59.2 kg, and 25.0 $kg/m^2$ for women, respectively. The mean daily intakes of total food and energy were 1219.1 g and 1740.9 kcal for men and 1071.3 g and 1432.6 kcal for women, respectively. The mean daily isoflavones (daidzein + genistein) intake of men and women were 20.0 mg and 14.2 mg, respectively. Blood pressure of the subjects was 128.3/75.5 mmHg for men and 124.1/73.7 mmHg for women. Serum lipids of men and women were 180.2 and 184.9 mg/dL for total cholesterol, 160.8 and 137.6 mg/dL for triglyceride, 41.5 and 44.7 mg/dL for HDL-cholesterol, 106.6 and 112.7 mg/dL for LDL-cholesterol, and 3.5 and 3.3 for atherogenic index, respectively. Serum triglyceride and atherogenic index of men were significantly higher than those of women. In men, isoflavone intake and the level of total serum cholesterol were negatively (p < 0.05) correlated, after adjusted age. In women, there were significant correlations between isoflavone intake and blood pressure (systolic and diastolic), after adjusted age (p < 0.05). Based on these results, we concluded that higher isoflavone intake seemed to be related to a better lipid profile in men and lower blood pressure in women. But more epidemiological studies and controlled clinical trials would help to confirm the optimal amount required for the prevention and treatment of cardiovascular disease.