• Preventive Nutrition and Food Science
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• v.4 no.3
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• pp.200-202
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• 1999

The effectsof garlic vinegar supplementation on body weight, blood blucose, and plasma triglyceride and cholesterol were investigated in streptozotocin -induced diabetic rats fed high-cholesterol(1%) diet for 4 wk. The garlic vinegar was made by fermenting 20% frsh garlic juice. There was no effect of garlic vinegar on body weight, plasma glucose or triglyceride concentrations in the diabetic rats. Plasma total -cholesterol concentrations were unaffected by garlic vinegarr supplementation. However, plasma LDL-cholesterol concentrations and atherogenic index were significantly lower in the diabetic rats supplemented with garlic vinegar diet than tin the cotnrol rats. The diabetic-rats supplemented with garlic vinegar not only had increased HDL-cholesterol levels but had decreased LDL-cholesterol. This alteration in the HDL/LDL-cholesterol ratio in the diabetic rats may decrease the risk of atheroscelrosis. Therefore, the over-all effect of garlic vinegar supplement may contribute to the antiatherogenic role in streptozotocin-induced diabetic rats.

• Nutrition Research and Practice
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• v.11 no.6
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• pp.479-486
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• 2017

BACKGROUND/OBJECTIVES: Timing of almond intake during a day may result differently in the perspectives of body composition and changes of lipid profile. The current study was conducted to compare the effects of daily almond intake as a preload versus as a snack on body composition, blood lipid profile, and oxidative and inflammation indicators among young Korean adults aged 20-39 years old. SUBJECTS/METHODS: Participants were randomly assigned to one of three groups: a pre-meal almond group (PM), a snack almond group (SN) in which participants were instructed to consume 56 g of almonds either as a preload before meals or as a snack between meals, respectively, and a control group (CL) in which participants were provided high-carbohydrate iso-caloric control food. Measurements were performed at baseline, weeks 8 and 16. RESULTS: A total of 169 (M 77 / F 92) out of the 227 participants completed the study between June 2014 and June 2015 (n = 58 for PM; 55 for SN; and 56 for CL). A significant decrease in body fat mass was observed in the PM group at both weeks 8 and 16 compared with the CL. There were significant intervention effects on changes of body fat mass (P = 0.025), body fat percentages (P = 0.019), and visceral fat levels (P < 0.001). Consuming almonds as a daily snack reduced the levels of total cholesterol (P = 0.043) and low-density lipoprotein (LDL) cholesterol (P = 0.011) without changing high-density lipoprotein (HDL) cholesterol compared with the CL. CONCLUSION: Almond consumption as a preload modified body fat percentages, whereas snacking on almonds between meals improved blood lipid profiles. This trial was registered at ClinicalTrials.gov as NCT03014531.

• Korean Journal of Community Nutrition
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• v.11 no.1
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• pp.133-142
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• 2006

Antioxidant vitamin supplementation focuses one's attention on the prevention of age-related diseases. This study was conducted to investigate the antioxidant status and lipid profiles and to look into the antioxidant vitamin supplementation that affects lipid metabolism in 20 elderly non-smoking Korean women (placebo group: n = 6, vitC suppl: n = 7, vitE suppl: n = 7). Age, height, weight, muscle, percent of fat and WHR were not significantly different among the groups, however $\%$ of fat was above $33\%$ and WHR was above 0.9. And blood pressure of the placebo group was 131.7/81.7 (border line hypertension), that of vitamin C supplement was 141.4/87.1 (hypertension) and that of vitamin E supplement was 151.4/92.9 (hypertension). Although nutrient intakes of all groups were poor, antioxidant status (blood vitamins C, E, A, and beta-carotene) and lipid profile (TG, total-cholesterol, VLDL-cholesterol, LDL-cholesterol, HDL-cholesterol) were normal. For nutritional intervention, the vitamin C supplement group received L-ascorbic acid 1,000 mg, and vitamin E supplement group received d-alpha-tocopherol 400IU for 4 weeks, showing the effects of vitamin E supplementation. Response total cholesterol of HDL-cholesterol (T-Chol/HDL) in vitamin E supplement group was significantly decreased from 4.3 to 3.2. And response LDL-cholesterol of HDL-cholesterol (LDL/HDL) in the vitamin E supplement group was also significantly decreased from 2.6 to 1.7. In addition, after the adjustment for plasma lipids (TG, total cholesterol), plasma vitamin A levels in vitamin E supplement group were significantly increased from 7.89 mg/g to 14.91 mg/g. And systolic blood pressure in vitamin E supplement group was significantly reduced. These results suggested that vitamin E supplementation affects the lipid profiles and blood pressure in elderly non-smoking women. So various nutrition programs must be implemented against age-related diseases and further studies are needed regarding sorts and amounts of antioxidant nutrients and supplementation periods.

• Journal of the Korean Society of Food Science and Nutrition
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• v.37 no.12
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• pp.1583-1588
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• 2008

The purpose of this work was to study the relationships between dietary intake and serum lipid profile in 293 adult subjects (mean age: $45.9{\pm}0.7$, men: 163, women: 130) who visited health promotion center. The anthropometric and biochemical blood indices were measured, and nutritional intakes were assessed using a food frequency questionnaire method. The subjects were divided by three groups in accordance with a standard for treating hyperlipidemia; those who had blood cholesterol levels above 240 mL/dL or triglyceride levels above 200 mL/dL were put into the risk group (Risk), while those with blood cholesterol levels below 200 mL/dL and triglyceride levels below 150 mL/dL were put into the control group (Control). Subjects who were between the two groups in terms of blood cholesterol and triglyceride levels were put into the borderline group (Borderline). Risk group showed significantly higher body mass index, body weight, waist circumference, and fat content compared to control group. The levels of calorie, carbohydrate, fat, and protein intake were significantly higher in the risk group than control group. There were significantly positive correlations between dietary calorie, carbohydrate, fat, and protein intake and blood triglyceride concentration. The blood HDL-cholesterol concentration had negative correlation with carbohydrate intake. These results suggested that overeating may be one of important factors affecting hyperlipidemia in Korean adults.

• Journal of the Korean Dietetic Association
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• v.13 no.1
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• pp.30-37
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• 2007

The purpose of this study was to compare the nutrient intakes, blood pressure, and blood lipids in Korean adults according to BMI. Subjects were recruited and divided into three groups according to BMI, which included normal group (18.5$\leq$BMI<23), overweight group (23$\leq$BMI<25), obese group (25$\leq$BMI). The average age, height, weight, BMI of the subjects were 53.1years, 159.2cm, 54.5kg, 21.4kg/$m^2$ for normal group, 52.3years, 159.4cm, 61.4kg, 24.1kg/$m^2$ for overweight group, 55.9years, 158.7cm, 68.5kg, 27.2kg/$m^2$ for obese group, respectively. There were not significant differences in energy and food intakes by BMI groups. The blood pressure, serum cholesterol, serum triglyceride, serum LDL-cholesterol, and AI were significantly increased and serum HDL-cholesterol decreased with increment of BMI. The age and BMI were significantly positively correlated with blood pressure and serum lipids except HDL-cholesterol. There was significantly negative correlation between percentage of protein energy intake and AI. To summarize these results, energy, nutrient, and food intakes were not significantly correlated with BMI, and blood pressure and blood lipids increased with increment of BMI. Further systematic study of relation among nutrient intakes including various life factors, BMI, blood pressure, and blood lipid profile is needed.

• Journal of the Korean Dietetic Association
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• v.5 no.2
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• pp.145-152
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• 1999

This study was to investigate the risk factors for the development of diabetes mellitus on healthy offsprings of Korea non-insulin dependent diabetes mellitus(NIDDM) patients. Forty four offsprings who have at least 1 parent with NIDDM and age, sex and body mass index(BMI) matched forty four healthy control subjects were collected for this study. BMI, skinfold thickness, waist/hip circumference ratio(WHR), fasting blood glucose, serum insulin, serum lipid profile, nutrient intakes and food behaviors were measured. There were no significant difference in BMI, WHR, fasting blood glucose, insulin, total cholesterol, triglyceride and daily nutrients intake between offsprings and controls. But skinfold thickness, LDL-cholesterol level and sweety food eating frequency were significantly higher in male offsprings than in male controls. And HDL-cholesterol was significantly lower in male offsprings than in male controls. Although there were no significant difference, offsprings had a overeating habit and ate more confectionery and greasy food than controls.

• Nutrition Research and Practice
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• v.3 no.1
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• pp.31-37
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• 2009

Recently, Korean people are consuming seaweeds almost 3.5 times more now than three decades ago. It is well known that seaweeds contain lots of soluble dietary fiber in addition to micronutrients such as ${\beta}$-carotene, iodine and some bioactive components. Seaweeds are considered to be effective for preventing chronic diseases including obesity, diabetes mellitus, atherosclerosis, cancer or constipation. This study was conducted to investigate the effect of seamustard intake on body weight gain, blood glucose level and lipid profiles in rats fed diets with different energy nutrient composition. Male Sprague-Dawley rats (average initial weight 103.7g) were divided into groups for two experiments as follows; Control, M2.5 & M5 groups (Exp. I) and M5, M10, HCM5, HCM10, HFM5 & HFM10 groups (Exp. II). The rats were fed diet and water ad libitum for 4 weeks. In general, there was no significant difference in blood glucose and triglyceride concentration among groups. In Exp. I, serum LDL-cholesterol level of rats fed diet with 5% seamustard powder (M5) was significantly lower than that of control group, while HDL-cholesterol level, TC/LDL ratio and weight of adrenal gland were higher. In Exp. II, food intake, body weight gain and EER of high fat diet with 10% seamustard group (HFM10) were the lowest among groups. Except gastrocnemius muscle, all organ weights of HFM10 group were the lowest. Fecal cholesterol excretion and serum LDL-cholesterol concentration of HFM10 group were the highest, while serum HDL-cholesterol level was the lowest among groups. Interestingly, HDL-cholesterol concentration was the highest in HCM5 group among groups. From these results, it was suggested that seamustard intake might be more effective for body weight control, but not for improving blood lipid profiles in high fat diet than in high carbohydrate diet.

• Journal of Animal Science and Technology
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• v.47 no.2
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• pp.233-242
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• 2005

Effects of supplemental charcoal powder and vitamin A on growth performance, serum profile and carcass characteristics with 24 Hanwoo steers were inves$\ell$ated. The Hanwoo steers were randomly assigned to one of the three dietary treatments: 1) Control(commercial feed), 2) Tl(commercial feed supplemented with 2% charcoal powder and 0.2 % vitamin A), 3) T2(commercial feed with 2 % charcoal powder). In the age 26 month, body weight of control Tl and T2 were 633.8 kg, 621.0 kg, 619.4 kg, respectively, with not significantly different(P> 0.05). The daily weight gain of control was the highest followed by Tl and T2. The contents of vitamin A(retinol) and total cholesterol in the blood of Tl was higher Tl(56.32 $\ell$ / dt, 163.83 mg/ dz) than the other treatment groups(P < 0.05). The average of WBC value in the blood was 6.86-" 9.83 k / ${\mu}\ell$, RBC value was 7.98 - 11.26 k / ${\mu}\ell$ and blood platelet was 236.7 - 287.0 k / ${\mu}\ell$. But The serum profile in blood was not significantly different between control and treatment groups. The carcass grade and characteristics of all treatments in Hanwoo steers were not significantly different except the texture.

• Food Science of Animal Resources
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• v.32 no.5
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• pp.584-590
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• 2012

This study evaluated the effects of carnosine supplementation on carnosine concentration in muscles and blood biochemical indices of rats. Thirty-two eight-week-old Sprague-Dawley male rats were randomly divided into a control group (CON) as well as three carnosine-treated groups. The carnosine-treated groups included groups fed diets composed of 0.01% carnosine (LC), 0.1% carnosine (MC), and 1.0% carnosine (HC). Body weight gain, food intake, feed efficacy rate, protein efficacy rate, and organ weights were not significantly different among the groups. In all groups, the mean carnosine levels in gastrocnemius muscles were higher than the mean carnosine levels in soleus muscles. Carnosine concentrations in soleus muscles and gastrocnemius muscles were significantly higher in the HC group compared to all other groups (p<0.05). Serum triglyceride and LDL-cholesterol concentrations in all of the carnosine-supplemented groups were significantly lower than those of the control group (p<0.05), while HDL-cholesterol levels were significantly higher than those of the control group (p<0.05). Aspartate aminotransferase levels in rats supplemented with carnosine were significantly higher than those of the control group. In conclusion, diets supplemented with high levels of carnosine can increase carnosine concentrations in skeletal muscles, which might contribute to increased exercise capacity. Furthermore, these findings suggest that high levels of dietary carnosine improve the lipid profile of rats by lowering blood LDL-cholesterol and increasing HDL-cholesterol levels.

• International journal of advanced smart convergence
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• v.11 no.3
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• pp.170-178
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• 2022

Purpose: Gardening has been reported to have positive emotional and physical effects in older adults. However, limited studies have assessed this relationship in Korea. Therefore, in this pilot study of densely populated urban dwellers, we aimed to investigate whether temporary but repeated experiences of the natural environment could positively change metabolism-related blood indicators. Methods: This study used pre- and post-interventional designs to investigate the effects of 16 weeks of gardening on lipid profiles in an urban adult population and investigate their relationships. This study was conducted 30 times at the H Botanical Garden in Yongin City from August 16, 2021 to November 30, 2021 (16 weeks, twice a week, 3 hours each time). Before and after the gardening program, a clinical pathologist collected blood samples from the participants. Results: High-density lipoprotein levels increased, low-density lipoprotein levels decreased, and total cholesterol levels decreased after the gardening activity. Conclusions: Our findings suggest that gardening has potential for clinical application as it has good control over the lipid profile through physical activity. These findings can be used as basic data for studying the relationship between urban populations and their living environment and for various studies in the future as experiencing the natural environment provides many health benefits.