• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.287-294
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• 2018

This thesis covers legal aspects of the crypto-currency exchange and the legal rights of crypto-currencies holders. Unlike financial markets in which central authorities or intermediaries determine the validity of transactions and manage records, crypto-currency markets utilize a decentralization system based on block chain technology. Such distinct characteristics distinguish crypto-currency from currency, notes, or financial instruments. Therefore, we need to check closely the legal principles that are applicable to crypto-currency. Crypto-currency users possess rights indirectly through the crypto-currency exchange. However, we should look at whether crypto-currency can be an object of ownership. This research found that legal protection for crypto-currency exchanges are limited. Domestic laws have many shortcomings to protect users' rights. This study found that users who incurred damages due to internet computation errors at exchanges require a protective system like stock markets. Therefore, studies on the legal controls and system regulations are required to protect users' rights. Also, crypto-currency information exchanges keep inside and protections for users' private information need to be further examined.

• Journal of Science and Technology Studies
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• v.18 no.3
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• pp.217-255
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• 2018

Bitcoin, which appeared in 2008, was merely a conceptual virtual currency, but it now enjoys the status as actual money. Bitcoin is an electronic money system that can be traded directly without a central trust institution. Thanks to the popularization of Bitcoin, blockchain technology has become a widespread concern. That technology is expanding not only the currency mechanism, but also a variety of other services. The possibility of a blockchain in relation to actual currency is ongoing. This paper investigates the technological characteristics and social construction of the blockchain by comparing the cases of Bitcoin, Namecoin, and MediBloc among blockchain applications. Namecoin emerged in 2013 is an attempt to replace the centralized Internet Domain Name System(DNS). There has been controversy over that current system for a long time, but replacing the already established system is not easy. Nevertheless, Namecoin has potential as an alternative. Meanwhile, MediBloc is an application that involves distributed management of medical data in South Korea. MediBloc claims that the key producers of medical data are patients themselves. This is to challenge to the question who is a knowledge producer of medical data. Through these three cases, it has discussed that blockchain technology does supports to form more democratic decision-making or simply provide a technical solution as automation. As a citizen, we can intervene in the realization of blockchains by presenting social agenda. This will be a method of the social construction of technology.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.3
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• pp.346-354
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• 2021

Since 2015, Blockchain has experienced rapid development throughout the world, institutions including Central Banks, Government Departments, Commercial Banks, IT Giants are all accelerating their exploration on Blockchain, and investment on Blockchain related R&D departments and start-up companies also shows explosive growth. This paper studies the impact of blockchain technology on banks' conventional trade settlement methods and describes blockchain technology in term of its concepts, advantages, and disadvantages. It also studies the application processes of blockchain technology combined with conventional trade settlement methods (remittance, collection, and L/C), and analyzes the positive and negative impacts of blockchain technology on the conventional trade settlement methods. In addition, this paper lists the blockchain application cases, analyzes the technology development status and existing problems, and puts forward suggestions and measures for the development of blockchain finance in China based on the case analysis and impact research.

• Smart Media Journal
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• v.10 no.1
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• pp.88-98
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• 2021

As blockchain technology has emerged as a security issue for IoT, technology which integrates block chain into IoT is being studied. In this paper is a research concerning token-based IoT service access control technology for data sharing, which propose a possessor focused data sharing technic by using the permissioned blockchain. To share IoT health data, a Hyperledger Fabric Network consisting of three organizations was designed to provide a way to share data by applying different access control policies centered on device owners for different services. In the proposed system, the device owner issues access control tokens with different security levels applied to the participants in the organization, and the token issue information is shared through the distributed ledger of the HFN. In IoT, it is possible to lightweight the access control processing of IoT devices by granting tokens to service requesters who request access to data. Furthmore, by sharing token issuance information among network participants using HFN, the integrity of the token is guaranteed and all network participants can trust the token. The device owners can trust that their data is being used within their authorized rights, and control the collection and use of data.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.4
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• pp.239-253
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• 2022

Epithelial-mesenchymal transition (EMT) is known to be involved in airway remodeling and fibrosis of bronchial asthma. However, the molecular mechanisms leading to EMT have yet to be fully clarified. The current study was designed to reveal the potential mechanism of microRNA-21 (miR-21) and poly (ADP-ribose) polymerase-1 (PARP-1) affecting EMT through the PI3K/AKT signaling pathway. Human bronchial epithelial cells (16HBE cells) were transfected with miR-21 mimics/inhibitors and PARP-1 plasmid/small interfering RNA (siRNA). A dual luciferase reporter assay and biotin-labeled RNA pull-down experiments were conducted to verify the targeting relationship between miR-21 mimics and PARP-1. The migration ability of 16HBE cells was evaluated by Transwell assay. Quantitative real-time polymerase chain reaction and Western blotting experiments were applied to determine the expression of Snail, ZEB1, E-cadherin, N-cadherin, Vimentin, and PARP-1. The effects of the PI3K inhibitor LY294002 on the migration of 16HBE cells and EMT were investigated. Overexpression of miR-21 mimics induced migration and EMT of 16HBE cells, which was significantly inhibited by overexpression of PARP-1. Our findings showed that PARP-1 was a direct target of miR-21, and that miR-21 targeted PARP-1 to promote migration and EMT of 16HBE cells through the PI3K/AKT signaling pathway. Using LY294002 to block PI3K/AKT signaling pathway resulted in a significant reduction in the migration and EMT of 16HBE cells. These results suggest that miR-21 promotes EMT and migration of HBE cells by targeting PARP-1. Additionally, the PI3K/AKT signaling pathway might be involved in this mechanism, which could indicate its usefulness as a therapeutic target for asthma.

• The Journal of the Convergence on Culture Technology
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• v.8 no.6
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• pp.675-683
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• 2022

Blockchain, which is the basis of virtual assets such as cryptocurrency, is receiving great attention as one of the cornerstone technologies of the 4th industrial revolution. Blockchain is a technology that can fundamentally change our lives not only in finance, but also in politics, logistics, and culture. However, it shows lower-than-expected usability because it is complicated to learn and is continuously being developed. In this study, we tried to investigate whether the Technology Acceptance Model(TAM) of virtual assets can be changed through education on the underlying technology, blockchain. A video-based online experiment was conducted with a total of 103 participants and examined how the type of training(positive, negative) and measurement timing(before, after) affect perceived usefulness, perceived ease of use, acceptance, which are TAM variables, and trust and security, which are related to blockchain characteristics. As a result of the experiment, interactions were found in all dependent variables according to the type of education and measurement timing. Specifically, groups that received negative education had no difference in all variables before and after, but it was found that groups that received positive education showed an increase afterwards. Through this, it can be seen that the effect of education based on the anchoring effect is also shown in the intention to use virtual assets using block chain technology, suggesting that the intention to use blockchain related technology can be increased through positive education.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.582-583
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• 2021

As the production of new and renewable energy such as solar and wind power has diversified, microgrid systems that can simultaneously produce and consume have been introduced. . In general, a decrease in electricity prices through solar power is expected in summer, so producer protection is required. In this paper, we propose a transparent and safe gift power transaction system between users using blockchain in a microgrid environment. A futures is simply a contract in which the buyer is obligated to buy electricity or the seller is obliged to sell electricity at a fixed price and a predetermined futures price. This system proposes a futures trading algorithm that searches for futures prices and concludes power transactions with automated operations without user intervention by using a smart contract, a reliable executable code within the blockchain network. If a power producer thinks that the price during the peak production period (Hajj) is likely to decrease during production planning, it sells futures first in the futures market and buys back futures during the peak production period (Haj) to make a profit in the spot market. losses can be compensated. In addition, if there is a risk that the price of electricity will rise when a sales contract is concluded, a broker can compensate for a loss in the spot market by first buying futures in the futures market and liquidating futures when the sales contract is fulfilled.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2021.10a
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• pp.584-585
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• 2021

As the production of new and renewable energy such as solar and wind power has diversified, microgrid systems that can simultaneously produce and consume have been introduced. In general, a decrease in electricity prices through solar power is expected in summer, so producer protection is required. In this paper, we propose a transparent and safe gift power transaction system between users using blockchain in a microgrid environment. A futures is simply a contract in which the buyer is obligated to buy electricity or the seller is obliged to sell electricity at a fixed price and a predetermined futures price. This system proposes a futures trading algorithm that searches for futures prices and concludes power transactions with automated operations without user intervention by using a smart contract, a reliable executable code within the blockchain network. If a power producer thinks that the price during the peak production period is likely to decrease during production planning, it sells futures first in the futures market and buys back futures during the peak production period to make a profit in the spot market. losses can be compensated. In addition, if there is a risk that the price of electricity will rise when a sales contract is concluded, a broker can compensate for a loss in the spot market by first buying futures in the futures market and liquidating futures when the sales contract is fulfilled.

• Information Systems Review
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• v.21 no.2
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• pp.117-137
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• 2019

In the Big Data era, data science has become popular with the production of numerous data in various domains, and the power of data has become a competitive power. There is a growing interest in unstructured data, which accounts for more than 80% of the world's data. Along with the everyday use of social media, most of the unstructured data is in the form of text data and plays an important role in various areas such as marketing, finance, and distribution. However, text mining using social media is difficult to access and difficult to use compared to data mining using numerical data. Thus, this study aims to develop Korean Natural Language Application (KoALA) as an integrated application for easy and handy social media text mining without relying on programming language or high-level hardware or solution. KoALA is a specialized application for social media text mining. It is an integrated application that can analyze both Korean and English. KoALA handles the entire process from data collection to preprocessing, analysis and visualization. This paper describes the process of designing, implementing, and applying KoALA applications using the design science methodology. Lastly, we will discuss practical use of KoALA through a block-chain business case. Through this paper, we hope to popularize social media text mining and utilize it for practical and academic use in various domains.

• Journal of Chest Surgery
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• v.39 no.7 s.264
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• pp.527-533
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• 2006

Background: A retrospective study was conducted to analyze the results of St. Jude Medical mitral valve replacement at the Chonbuk National University Hospital since the initial implant in May 1984. Material and Method: Between May of 1984 and December of 1996, 95 patients underwent MVR with the St. Jude Medical mechanical valve prosthesis at Department of Medical Science of Chonbuk National University Hospital and follow-up ended in May of 2004. Result: Age ranged from 19 to 69 years. Follow-up (mean${\pm}$standard deviation) averaged $10.6{\pm}4.2\;year$. Thirty-day operative mortality was 4.2% (4/95). Nine late deaths have occurred and actuarial survival was $90.5{\pm}3.0%,\;87.9{\pm}3.4%\;and\;83.2{\pm}4.6%$ at 5, 10 and 20 years, respectively. Probability of freedom from valve-rotated death was $95.5{\pm}2.1%,\;94.3{\pm}2.4%\;and\;91.0{\pm}3.9%$ at 5, 10 and 20 years, respectively. Seven patients have sustained thromboembolic events (1,05%/patient-year). Fifteen patients had anticoagulation related hemorrhage (3.56%/patient-year). There was no structural valve deterioration. Probability of freedom from all complications was $82.0{\pm}3.9%,\;71.3{\pm}4.8%\;and\;42.4{\pm}10.5%$ at 5, 10 and 20 years, respectively. Conclusion: We confirm the effective and excellent durability of the St. Jude Medical prosthesis in the mitral position with a low event rate at long-term follow-up. It also demonstrates the commonly encountered practical difficulty of adjusting the anti-coagulation protocol in patients with prosthetic mitral valves.