• Title/Summary/Keyword: blindness

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Fatty Acid Concentration of Serum Phospholipids in Normal and Glaucoma Patients (정상인과 녹내장 환자의 혈청 인지질 지방산 농도)

  • Chung, Hae-Yun
    • Journal of the Korean Society of Food Culture
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    • v.35 no.2
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    • pp.224-232
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    • 2020
  • Glaucoma is one of the leading causes of blindness worldwide and is characterized by degeneration of the optic nerve. Elevated intraocular pressure (IOP) is the major contributing factor to optic nerve damage. However, some patients develop glaucoma even with normal IOP. Other factors, including age, race, myopia, and nutrition, can affect glaucoma risk. Dietary fat intake and serum fatty acid composition are closely related with the fatty acid profile of the retina and thus can modulate glaucoma risk. In this study, we collected serum samples from 34 glaucoma patients (26 primary open angle glaucoma (POAG) and 8 normal tension glaucoma (NTG)) and 45 healthy controls and analyzed their serum phospholipid fatty acid concentrations. The results show that the ratio of oleic acid to stearic acid (OA/SA), which is an indicator of stearoyl-CoA desaturase activity, was higher in POAG patients when compared to normal controls. The ratio of eicosapentaenoic acid to arachidonic acid (EPA/AA), which is an indirect marker of eicosanoid biosynthesis, was also higher in glaucoma patients (p=0.048). These results imply that dietary fatty acid intake and serum fatty acid profile can influence glaucoma risk. Additional study is necessary to identify the relationship between fatty acids and glaucoma.

Influencing factors and prediction of carbon dioxide emissions using factor analysis and optimized least squares support vector machine

  • Wei, Siwei;Wang, Ting;Li, Yanbin
    • Environmental Engineering Research
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    • v.22 no.2
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    • pp.175-185
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    • 2017
  • As the energy and environmental problems are increasingly severe, researches about carbon dioxide emissions has aroused widespread concern. The accurate prediction of carbon dioxide emissions is essential for carbon emissions controlling. In this paper, we analyze the relationship between carbon dioxide emissions and influencing factors in a comprehensive way through correlation analysis and regression analysis, achieving the effective screening of key factors from 16 preliminary selected factors including GDP, total population, total energy consumption, power generation, steel production coal consumption, private owned automobile quantity, etc. Then fruit fly algorithm is used to optimize the parameters of least squares support vector machine. And the optimized model is used for prediction, overcoming the blindness of parameter selection in least squares support vector machine and maximizing the training speed and global searching ability accordingly. The results show that the prediction accuracy of carbon dioxide emissions is improved effectively. Besides, we conclude economic and environmental policy implications on the basis of analysis and calculation.

Factors Associated with Senile Macular Degeneration in Elders within Communities (지역사회거주 노인의 황반변성 관련 요인)

  • Kim, Chul-Gyu;Park, Yungeong;Park, Seungmi
    • Research in Community and Public Health Nursing
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    • v.24 no.1
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    • pp.1-10
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    • 2013
  • Purpose: This study was conducted to examine the degree of senile macular degeneration in elders aged 65 or older and identify factors associated with senile macular degeneration in elders within communities. Methods: Participants in this cross-sectional descriptive study were 388 elders without cataract, glaucoma, and diabetic retinopathy. Data were collected through face to face interviews using a questionnaire in an urban area from June 2010 to December 2011. To detect senile macular degeneration, the participants' self-tests were carried out with Amsler grid testing. Stepwise multivariate logistic regression was performed to evaluate the effects of health behavior and knowledge about eye health on senile macular degeneration. Results: The proportion of participants with senile macular degeneration was 11.6%. Factors that significantly increased the risk of senile macular degeneration included eye discomfort and history of ophthalmic examination (p<.05). Factors that significantly decreased the risk of senile macular degeneration included regular change of magnifiers, non-use of magnifiers, and knowledge about preventive effects of non-smoking and antioxidant vitamin intake on senile macular degeneration (p<.05). Conclusion: This study showed that programs for preventing senile macular degeneration were necessary for elders within communities and the results of this study can be used for developing those programs.

A New Route Optimization Scheme for Network Mobility: Combining ORC Protocol with RRH and Using Quota Mechanism

  • Kong, Ruoshan;Feng, Jing;Gao, Ren;Zhou, Huaibei
    • Journal of Communications and Networks
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    • v.14 no.1
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    • pp.91-103
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    • 2012
  • Network mobility (NEMO) based on mobile IP version 6 has been proposed for networks that move as a whole. Route optimization is one of the most important topics in the field of NEMO. The current NEMO basic support protocol defines only the basic working mode for NEMO, and the route optimization problem is not mentioned. Some optimization schemes have been proposed in recent years, but they have limitations. A new NEMO route optimization scheme-involving a combination of the optimized route cache protocol (ORC) and reverse routing header (RRH) and the use of a quota mechanism for optimized sessions (OwR)-is proposed. This scheme focuses on balanced performance in different aspects. It combines the ORC and RRH schemes, and some improvements are made in the session selection mechanism to avoid blindness during route optimization. Simulation results for OwR show great similarity with those for ORC and RRH. Generally speaking, the OwR's performance is at least as good as that of the RRH, and besides, the OwR scheme is capable of setting up optimal routing for a certain number of sessions, so the performance can be improved and the cost of optimal routing in nested NEMO can be decreased.

Maturation-Resistant Dendritic Cells Ameliorate Experimental Autoimmune Uveoretinitis

  • Oh, Keun-Hee;Kim, Yon-Su;Lee, Dong-Sup
    • IMMUNE NETWORK
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    • v.11 no.6
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    • pp.399-405
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    • 2011
  • Background: Endogenous uveitis is a chronic inflammatory eye disease of human, which frequently leads to blindness. Experimental autoimmune uveoretinitis (EAU) is an animal disease model of human endogenous uveitis and can be induced in susceptible animals by immunization with retinal antigens. EAU resembles the key immunological characteristics of human disease in that both are $CD4^+$ T-cell mediated diseases. Dendritic cells (DCs) are specialized antigen-presenting cells that are uniquely capable of activating naive T cells. Regulation of immune responses through modulation of DCs has thus been tried extensively. Recently our group reported that donor strain-derived immature DC pretreatment successfully controlled the adverse immune response during allogeneic transplantation. Methods: EAU was induced by immunization with human interphotoreceptor retinoid-binding protein (IRBP) $peptide_{1-20}$. Dendritic cells were differentiated from bone marrow in the presence of recombinant GM-CSF. Results: In this study, we used paraformaldehyde-fixed bone marrow-derived DCs to maintain them in an immature state. Pretreatment with fixed immature DCs, but not fixed mature DCs, ameliorated the disease progression of EAU by inhibiting uveitogenic $CD4^+$ T cell activation and differentiation. Conclusion: Application of iBMDC prepared according to the protocol of this study would provide an important treatment modality for the autoimmune diseases and transplantation rejection.

Chopper Controller Based DC Voltage Control Strategy for Cascaded Multilevel STATCOM

  • Xiong, Lian-Song;Zhuo, Fang
    • Journal of Electrical Engineering and Technology
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    • v.9 no.2
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    • pp.576-588
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    • 2014
  • The superiority of CMI (Cascaded Multilevel Inverter) is unparalleled in high power and high voltage STATCOM (Static Synchronous Compensator). However, the parameters and operating conditions of each individual power unit composing the cascaded STATCOM differ from unit to unit, causing unit voltage disequilibrium on the DC side. This phenomenon seriously impairs the operation performance of STATCOM, and thus maintaining the DC voltage balance and stability becomes critical for cascaded STATCOM. This paper analyzes the case of voltage disequilibrium, combines the operation characteristics of the cascaded STATCOM, and proposes a new DC voltage control scheme with the advantages of good control performance and stability. This hierarchical control method uses software to achieve the total active power control and also uses chopper controllers to enable that the imbalance power can flow among the capacitors in order to keep DC capacitor voltages balance. The operating principle of the chopper controllers is analyzed and the implementation is presented. The major advantages of the proposed control strategy are that the number of PI regulators has been decreased remarkably and accordingly the blindness of system design and debugging also reduces obviously. The simulation reveals that the proposed control scheme can achieve the satisfactory control goals.

Clinical study on 1 Case of Patient with Obstruction of the retinal artery (網膜中心動脈閉鎖 患者 1例에 對한 臨床的 考察)

  • Lee, Jun-Seong;Ryu, Hyeon-Sin;Seo, Hyeon-Sik;No, Seok-Seon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.14 no.2
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    • pp.224-230
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    • 2001
  • In the Clinical study on 1 Case of Patient with Obstruction of the retinal artery, the results were as follows. 1. Obstruction of the retinal artery is acute disease that vision isdiminished fastly and become a blindness. 2. It belong to the cathegory of Pock Maeng(暴盲) in Oriental Medicine. 3. The causes of Obstruction of the retinal artery were the yin-deficiency of liver and kidney, the stagnation of vital energy and blood stasis, the abundance of phlegm-heat, the yang-deficiency of spleen and kidney, the yin-deficiency of spleen and kidney, the nonfastness of primordial energy etc. 4. We could get the effective result by providing the patient with Jinkansikpung-tang-gami(鎭肝熄風湯加味) in the acute period 5. In Acupuncture treament and other treament, Electro-acupuncture theraphy ana Lodestone theraphy were useo for neurologic stimulation, Body acupuncture and Auricula-acupuncture were used for promoting the circulation of vital energy and blood.

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A literatual studies on the cataract, glaucoma, bluish glaucoma (內障, 綠風內障, 靑風內障에 대한 文獻的 考察)

  • Park, Se-bong;Ko, Woo-shin
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.12 no.1
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    • pp.254-267
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    • 1999
  • Based on the research of cataract, glaucoma, bluish glaucoma, we have abtained the following results. 1. Main etiologies of the cataract are deficiency of the liver and kidneys, main symptoms are no nebula, no pain, no tear and sometimes light blue and white vision appear. 2. Main etiologies of glaucoma are receives heat from the liver, stagnation of the liver and gall bladder etc, main symptoms are both forehead corner pull each ether, pain from eye ball to nasal septum, headache, extending pain of the eyes, sometimes red and white flower vision appear, etc. 3. main etiologies of the bluish glaucoma are melancholy, wrath, stagnation of the liver, internal damage, flaming up fire of the phlegm, deficiency of the liver, deficiency of blood, etc, main symptoms are numbness, visual field constriction, blindness, reduce of visual capacity, blue flower vision sometimes appear, etc. 4. Treatments are mainly uses nourish Um(陰) to reduce pathogenic fire, relieve stagnancy of Ki(氣) of the liver, nourish Um(陰) of the liver and kidneys, etc, acupuncture points are mostly contended arounded eyes such as BL10)(天柱), GV16(風府), LR3)(太衝), HT5)(通里) and in the case of nauses and vomitting PC6)(內關, ST36)(足三里) are included in addition to the above.

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Slotted ALOHA Based Greedy Relay Selection in Large-scale Wireless Networks

  • Ouyang, Fengchen;Ge, Jianhua;Gong, Fengkui
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.10
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    • pp.3945-3964
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    • 2015
  • Since the decentralized structure and the blindness of a large-scale wireless network make it difficult to collect the real-time channel state or other information from random distributed relays, a fundamental question is whether it is feasible to perform the relay selection without this knowledge. In this paper, a Slotted ALOHA based Greedy Relay Selection (SAGRS) scheme is presented. The proposed scheme allows the relays satisfying the user's minimum transmission request to compete for selection by randomly accessing the channel through the slotted ALOHA protocol without the need for the information collection procedure. Moreover, a greedy selection mechanism is introduced with which a user can wait for an even better relay when a suitable one is successfully stored. The optimal access probability of a relay is determined through the utilization of the available relay region, a geographical region consisting of all the relays that satisfy the minimum transmission demand of the user. The average number of the selection slots and the failure probability of the scheme are analyzed in this paper. By simulations, the validation and the effectiveness of the SAGRS scheme are confirmed. With a balance between the selection slots and the instantaneous rate of the selected relay, the proposed scheme outperforms other random access selection schemes.

A Case of Systemic Lupus Erythematosus Presenting with Amaurosis Fugax without Antiphospholipid Antibodies Syndrome (항인지질항체증후군을 동반하지 않은 일과성 단안 실명으로 발현된 전신성 홍반성 루푸스 1 예)

  • Kim, Jung-Hyun;Hah, Jung-Sang;Park, Mee-Young;Lee, Se-Jin;Lee, Jun
    • Journal of Yeungnam Medical Science
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    • v.23 no.1
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    • pp.113-117
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    • 2006
  • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that may affect many organ systems including the nervous system. The immune response in patients with SLE can cause inflammation and other damage that can cause significant injury to the arteries and tissues. A 48-year-old woman was admitted to the hospital because of transient monocular blindness. Magnetic resonance imaging and conventional angiography showed severe stenosis of the distal intracranial internal carotid artery. The patient was diagnosed as having SLE but the antiphospholipid antibodies were negative. Amaurosis fugax has not been previously reported as an initial manifestation of SLE in Korea. We report a patient with a retinal transient ischemic attack as the first manifestation of SLE.

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