• Journal of Chest Surgery
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• 제21권1호
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• pp.26-35
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• 1988

The effect of cardiopulmonary bypass on platelet count, platelet function, and bleeding time was studied in 60 patients. Platelet count was significantly reduced during and after cardiopulmonary bypass. Platelet function also had a reduced aggregation response to adenosine diphosphate. Bleeding time was prolonged to over 30 minutes during cardiopulmonary bypass and not returned to normal level until postbypass 1 hour. The amount of postoperative bleeding was proportional to the degree of decrease in platelet count and function, degree of decrease in platelet count and function. There was no significant correlation between duration of cardiopulmonary bypass and platelet count, platelet function, bleeding time, or amount of postoperative bleeding. Patients with cyanotic congenital heart disease showed a larger amount of postoperative bleeding than patients with acyanotic congenital heart disease [P<0.01], and this difference was due to the fact that platelet function was more significantly affected by cardiopulmonary bypass in cyanotic group. Patients using membrane oxygenator showed a less amount of postoperative bleeding than patients using bubble oxygenator [p<0.005] reflecting better preservation of platelet count and function by membrane oxygenator.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2008년도 추계 학술발표회 제20권2호
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• pp.593-596
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• 2008

콘크리트의 블리딩은 재료분리의 일종으로서 콘크리트 품질뿐만 아니라 내구성을 저하시키는 원인으로 작용한다. 본 연구에서는 콘크리트 블리딩에 영향을 미칠 것으로 예상되는 시멘트 및 믹싱시간의 두 요인의 변화에 따른 특성을 파악하여 블리딩 제어기술 확보를 위한 기초자료를 제공하고자 한다.연구결과에 의하면, 믹싱시간이 증가할수록 블리딩율도 증가하는 추세를 나타내고 있었다. 블리딩양(믹싱시간 90초)은 시멘트 특성에 의한 차이가 뚜렷하게 나타나고 있었으며, 콘크리트 특성값(블리딩율, 슬럼프 및 재령 3일 압축강도)은 믹싱시간과 비례적인 관계가 있었다. 또한, 슬럼프 손실율과 믹싱시간은 반비례적인 관계가 존재하였고, 압축강도값은 초기재령에서만 믹싱시간에 의한 영향을받고 있었다.향후, 최적 믹싱시간 도출을 위한 다양한 검토가 필요할 것으로 판단된다.

• 임상간호연구
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• 제27권2호
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• pp.179-186
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• 2021

Purpose: The purpose of our study was to identify the bleeding risk factors and to validate the safety of shortening the bed rest time after bone marrow examination in pediatric hemato-oncologic patients. Methods: From July 2019 to September 2020, 145 patients were enrolled from a single center. Medical records were reviewed retrospectively. Descriptive statistics were presented, and the data were analyzed using 𝑥²-test, Fisher's exact test, and a logistic regression. Results: After two hours of bed rest, most of the patients (91.7%) did not have bleeding complications, and only 8.3% of the patients had a minor bleeding. The rate of major bleeding complications, including hematoma, retroperitoneal hemorrhage rate was zero. The bleeding complications was frequently found on bilateral procedures than unilateral procedures and the difference were statistically significant (p<.05). Conclusion: Two hours of bed rest time after bone marrow examination could be safe and adequate in pediatric hemato-oncologic patients.

• 한국가금학회지
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• 제32권3호
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• pp.187-193
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• 2005

본 연구는 닭고기 품질의 고급화를 위하여 육계의 도계과정에서 방혈 시간(30초, 90초, 150초)에 따른 닭고기의 육색 및 물리적 특성 및 저장 특성을 구명하고자 실시하였다. 닭고기의 도체의 pH는 방혈 시간의 변화에 따른 차이를 보이지 않았으며 pH의 값은 $5.8\~5.9$를 나타내었다. 육색의 변화에서 가슴살은 껍질 부위와 약간의 차이를 나타냈는데 방혈 시간이 증가함에 따라 황색도$(b^{\ast})$와 명도$(L^{\ast})$는 감소하는 경향을 나타낸 반면 적색도$(a^{\ast})$는 방혈 시간이 증가함에 따라 증가하는 경향을 나타내었고, 날개 부위의 명도$(L^{\ast})$는 방혈 시간이 증가함에 따라 증가하였으나 황색도$(b^{\ast})$와 적색도 $(b^{\ast})$는 거의 차이가 없었다. 다리살은 방혈 시간이 증가함에 따라 적색도$(a^{\ast})$는 감소하는 경향을 나타냈으나, 황색도$(b^{\ast})$ 및 명도$(L^{\ast})$는 증가하는 경향을 보였고, 창색도$(b^{\ast})$는 큰 차이를 보이지 않았다. 보수력은 방혈 시간이 증가할수록 63.64에서 61.06로 감소하는 경향을 나타냈으나 가열 감량은 27.16에서 29.22로 증가하는 경향을 나타내었고, 전단력은 방혈 시간이 높아갈수록 약간씩 증가하는 경향을 나타내었다. 저장시험은 폴리에틸렌으로 포장한 닭고기를 $4^{\circ}C$에서 3일간 저장 후 TBARS(지방산패도) 가는 저장시간이 증가할수록 방혈 시간에 관계없이 증가하는 경향을 나타냈었고, 150초 방혈 처리구가 가장 높은 TBARS가 변화를 나타냈다. 단백질의 변성을 나타내는 VBN 가는 저장 일시가 증가할수록 증가하는 경향을 나타냈으며, 방혈 시간이 비교적 가장 짧은 30초 수준에서 VBN 가가 가장 높았고, 150초 처리구에서 가장 낮은 값을 나타내었다. 육계 표면 미생물검사에서는 저장 3일째에 방혈 시간이 가장 짧은30초에서 총 균수(T. bacterial counts)가 $6.53 logCFU/cm^2$로 90초 처리구 및 150초 처리구보다 약간 증가하였으나 큰 차이를 나타내지 않았다.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2003년도 학술.기술논문 발표회
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• pp.69-72
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• 2003

This study is intended to investigate the fundamental properties of concrete which AE water reducing agent for reduction of bleeding is used, and the properties of bleeding reduction. According to the results, when the adding ratio of AE water reducing agent for reduction of bleeding increases, a range of normal fluidity and aimed air content arc satisfied, setting time is faster than that of normal AE water reducing agent. And bleeding amount decreases, bleeding speed is highest between 60 and 90 min, and sinking depth increases drastically in 60 min. When, AE water reducing agent for reduction of bleeding is added, compressive strength shows a slight variation by air content, but there is not a large influence by addition of AE water reducing agent for reduction of bleeding. Synthetically, it proves that AE water reducing agent for reduction of bleeding satisfies aimed air content in the range of normal slump and can reduce only bleeding without quality variation of compressive strength.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2003년도 학술.기술논문발표회
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• pp.69-72
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• 2003

This study is intended to investigate the fundamental properties of concrete which AE water reducing agent for reduction of bleeding is used, and the properties of bleeding reduction. According to the results, when the adding ratio of AE water reducing agent for reduction of bleeding increases, a range of normal fluidity and aimed air content are satisfied, setting time is faster than that of normal AE water reducing agent. And bleeding amount decreases, bleeding speed is highest between 60 and 90 min, and sinking depth increases drastically in 60 min. When. AE water reducing agent for reduction of bleeding is added, compressive strength shows a slight variation by air content, but there is not a large influence by addition of AE water reducing agent for reduction of bleeding. Synthetically, it proves that AE water reducing agent for reduction of bleeding satisfies aimed air content in the range of normal slump and can reduce only bleeding without quality variation of compressive strength.

• Neonatal Medicine
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• 제18권1호
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• pp.6-13
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• 2011

All newborn infants with clinically significant bleeding should be evaluated for a hemostatic deficit. Medical history should include the following data: familial bleeding disorders, maternal illness and medication, age of bleeding onset, and prophylactic administration of vitamin K. The first essential step for evaluating bleeding neonates is determining whether the baby is sick or well. The physician should also evaluate the extent of the bleeding, features of bleeding lesions, and other abnormal findings from the physical examination. Skeletal anomalies may provide diagnostic clues. Depending on the clinical features and results of screening tests, other tests including coagulation factors may be useful for determining the diagnosis. All laboratory results must be considered in the context of age-related reference values. The platelet function analyzer provides a promising alternative to bleeding time. Fibrin degradation products and D-dimers are used for screening and specially testing fibrinolytic activity, respectively. The Apt test may help to rule out factors derived from maternal blood. Radiologic imaging studies are important because asymptomatic intracranial hemorrhages are common in neonates.

• 한국건축시공학회지
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• 제4권1호
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• pp.133-140
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• 2004

This study is intended to investigate the properties of bleeding reduction of concrete using AE water reducing agent for the type of bleeding reduction with the replacement admixture. According to the results, when the adding ratio of AE water reducing agent for the type of bleeding reduction increases, a range of normal fluidity and aimed air content are satisfied, setting time is faster than that of normal AE water reducing agent. And bleeding amount decreases, bleeding speed is highest between 60 and 90 min, and sinking depth increases drastically in 50 min. When AE oater reducing agent for the type of bleeding reduction is added, compressive strength shows a slight variation by air content, but there is not a large influence by addition of AE water reducing agent for the type of bleeding reduction. Synthetically, it proves that AE water reducing agent for the type of bleeding reduction satisfies aimed air content in the range of normal slump and can reduce only bleeding without quality variation of compressive strength.

• 한국멀티미디어학회논문지
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• 제15권5호
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• pp.664-671
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• 2012

가상 의료 시뮬레이션을 통한 실습 교육은 학습 효과를 높이는 장점이 있기 때문에 최근 실제 의료 환경에 도입이 확대되고 있다. 특히 최소 침습적 수술 분야에서 가상 수술 의료 시뮬레이션의 필요성이 증가하고 있다. 하지만, 가상 수술 의료 시뮬레이션 환경에서 자주 발생하는 출혈 특수 효과를 현실감이 있게 표현하기 위한 출혈 애니메이션 기술은 아직까지 제안되지 않고 있다. 본 논문에서는 사실적인 실시간 출혈 애니메이션 기법을 제안한다. 제안 기법은 출혈 시뮬레이션을 위해서 주 출혈 방향 벡터 방향을 기준으로 주 출혈 영역과 유효 출혈 영역을 계산하여 자연스러운 출혈 효과의 표현이 가능하다. 또한, 출혈 렌더링을 위해서 정점들의 불투명도 값을 시그모이드 함수를 이용한 가중치 부여로 부드러운 불투명도 변화를 통하여 사실적이고, 자연스러운 출혈 애니메이션이 가능하다. 본 논문에서 제안한 기법은 가상 수술 의료 시뮬레이션의 현실감, 몰입감을 증진시켜 이러한 시뮬레이션을 사용하는 의사 혹은 의대생들에 대한 교육의 효과를 증진시킬 수 있다.

• Journal of Gastric Cancer
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• 제22권1호
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• pp.47-55
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• 2022

Purpose: The use of direct oral Xa inhibitors (DXaIs) to prevent venothrombotic events is increasing. However, gastrointestinal bleeding, including that related to endoscopic resection, is a concern. In this study, we evaluated bleeding and coagulation times during the perioperative period of gastric endoscopic submucosal dissection (ESD). Materials and Methods: Patients who consecutively underwent gastric ESD from August 2016 to December 2018 were analyzed. Bleeding rates were compared among the 3 groups (antiplatelet, DXaIs, and control). DXaI administration was discontinued on the day of the procedure. Prothrombin time (PT), activated partial thromboplastin time, and the ratio of inhibited thrombin generation (RITG), which was based on dilute PT, were determined before and after ESD. Results: During the study period, 265 gastric ESDs were performed in 239 patients, where 23 and 50 patients received DXaIs and antiplatelets, respectively. Delayed bleeding occurred in 17 patients (7.4%) and 21 lesions (7.1%). The bleeding rate in the DXaI group was significantly higher than that in the other groups (30.4%, P<0.01), and the adjusted odds ratio of bleeding was 5.7 (95% confidence interval, 1.4-23.7; P=0.016). In patients using DXaIs, there was a significant (P=0.046) difference in the median RITG between bleeding cases (18.6%) and non-bleeding cases (3.8%). Conclusions: A one-day cessation of DXaIs was related to a high incidence of bleeding after gastric ESD, and monitoring of residual coagulation activity at trough levels might enable the predicted risk of delayed bleeding in patients using DXaIs.