• Title/Summary/Keyword: bleeding time

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Effect of Cardiopulmonary Bypass on Platelet (체외순환이 혈소판에 미치는 영향)

  • Choe, Jun-Yeong;Seo, Gyeong-Pil
    • Journal of Chest Surgery
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    • v.21 no.1
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    • pp.26-35
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    • 1988
  • The effect of cardiopulmonary bypass on platelet count, platelet function, and bleeding time was studied in 60 patients. Platelet count was significantly reduced during and after cardiopulmonary bypass. Platelet function also had a reduced aggregation response to adenosine diphosphate. Bleeding time was prolonged to over 30 minutes during cardiopulmonary bypass and not returned to normal level until postbypass 1 hour. The amount of postoperative bleeding was proportional to the degree of decrease in platelet count and function, degree of decrease in platelet count and function. There was no significant correlation between duration of cardiopulmonary bypass and platelet count, platelet function, bleeding time, or amount of postoperative bleeding. Patients with cyanotic congenital heart disease showed a larger amount of postoperative bleeding than patients with acyanotic congenital heart disease [P<0.01], and this difference was due to the fact that platelet function was more significantly affected by cardiopulmonary bypass in cyanotic group. Patients using membrane oxygenator showed a less amount of postoperative bleeding than patients using bubble oxygenator [p<0.005] reflecting better preservation of platelet count and function by membrane oxygenator.

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Influence of Cement and Mixing time Factor on the Bleeding of Concrete (콘크리트의 블리딩에 미치는 시멘트 및 믹싱시간의 영향)

  • Lee, Won-Am;Um, Tai-Sun;Lee, Jong-Ryul
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.593-596
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    • 2008
  • The bleeding of concrete is defined as a kind of separation of materials. The durability of concrete, as well as the quality caused by the bleeding. Therefore, This study is intended to find influence of cement and mixing time factor on the bleeding of concrete. We want to know two factors that determine the change, to provide it to our customers. According to the results, The bleeding ratio increase by the increase of mixing time factor. At the 90 second of mixing time, the amount of bleeding differ greatly from cement properties. This paper presents an experimental study on bleeding ratio, slump and compressive strength properties with three days. In addition, the mixing time is inversely related slump loss ratio, the initial value of the compressive strength is only affected by the mixing time. As a result, the bleeding of concrete was obtained that their characteristics depends on the cement and mixing time factor, also in the future, to derive optimum mixing time for a variety of review is necessary.

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A Study on Bleeding after Shortening the Bed Rest Time of Pediatric Hemato-oncologic Patients after Bone Marrow Examination (소아 혈액종양 환자의 골수검사 후 침상안정 시간 단축에 따른 출혈에 관한 연구)

  • Park, Mi Jeong;Lee, Hye Youn;Kim, Nam Yi;Lee, Ok Hee;Hwang, Yu Min
    • Journal of Korean Clinical Nursing Research
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    • v.27 no.2
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    • pp.179-186
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    • 2021
  • Purpose: The purpose of our study was to identify the bleeding risk factors and to validate the safety of shortening the bed rest time after bone marrow examination in pediatric hemato-oncologic patients. Methods: From July 2019 to September 2020, 145 patients were enrolled from a single center. Medical records were reviewed retrospectively. Descriptive statistics were presented, and the data were analyzed using 𝑥2-test, Fisher's exact test, and a logistic regression. Results: After two hours of bed rest, most of the patients (91.7%) did not have bleeding complications, and only 8.3% of the patients had a minor bleeding. The rate of major bleeding complications, including hematoma, retroperitoneal hemorrhage rate was zero. The bleeding complications was frequently found on bilateral procedures than unilateral procedures and the difference were statistically significant (p<.05). Conclusion: Two hours of bed rest time after bone marrow examination could be safe and adequate in pediatric hemato-oncologic patients.

Effect of Bleeding Time on Meat Quality and Shelf-Life of Broiler (방혈 시간이 닭고기의 품질 및 저장성에 미치는 영향)

  • Chae H. S.;Ahn C. N.;Yoo Y. M.;Ham J. S.;Jeong S. G.;Lee J. M.;Choi Y. I.
    • Korean Journal of Poultry Science
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    • v.32 no.3
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    • pp.187-193
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    • 2005
  • This study was carried out to investigate the effect of the bleeding times(30sec., 90sec., 150sec.) at slaughtering process on meat quality and storage properties of broiler. The redness$(a^{\ast}\;value)$ of skin, wing, leg muscle decreased at high bleeding time(150sec.). However, there was no significant difference in breast muscle. WHC(water holding capacity) of breast muscle decreased from $63.64\%$ at low bleeding time(30sec.) to $61.06\%$ at high bleeding time. TBARS(thiobarbituric acid-reactive substance) values were 0.18 mgMA/kg at the low bleeding time, 0.16 mgMA/kg at the middle bleeding time(90sec.) and 0.21mgMA/kg high bleeding time on 3 days of storage. Total aerobic plate counts(TPC) were $6.25logCFU/cm^2$ at the low bleeding time, $6.25logCFU/cm^2$ at the middle bleeding time and $6.53logCFU/cm^2$ at the high bleeding time. The TPC was increased as the bleeding time increased. In conclusion, meat color of chicken were acceptable when the carcasses were slaughtered at the high bleeding time.

Properties of Bleeding Reduction of Concrete Using AE Water Reducing Agent for Reduction of Bleeding (블리딩저감용 AE감수제를 사용한 콘크리트의 블리딩 저감 특성)

  • Kim, Ki-Hoon;Hwang, Yin-Seong;La, Woon;Im, Ju Hyeuk;Han, Cheon-Goo
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2003.11a
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    • pp.69-72
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    • 2003
  • This study is intended to investigate the fundamental properties of concrete which AE water reducing agent for reduction of bleeding is used, and the properties of bleeding reduction. According to the results, when the adding ratio of AE water reducing agent for reduction of bleeding increases, a range of normal fluidity and aimed air content arc satisfied, setting time is faster than that of normal AE water reducing agent. And bleeding amount decreases, bleeding speed is highest between 60 and 90 min, and sinking depth increases drastically in 60 min. When, AE water reducing agent for reduction of bleeding is added, compressive strength shows a slight variation by air content, but there is not a large influence by addition of AE water reducing agent for reduction of bleeding. Synthetically, it proves that AE water reducing agent for reduction of bleeding satisfies aimed air content in the range of normal slump and can reduce only bleeding without quality variation of compressive strength.

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Properties of Bleeding Reduction of Concrete Using AE Water Reducing Agent for Reduction of Bleeding (블리딩저감용 AE감수제를 사용한 콘크리트의 블리딩 저감 특성)

  • Kim, Ki-Hoon;Hwang, Yin-Seong;La, Woon;Im, Ju-Hyeuk;Han, Cheon-Goo
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2003.05a
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    • pp.69-72
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    • 2003
  • This study is intended to investigate the fundamental properties of concrete which AE water reducing agent for reduction of bleeding is used, and the properties of bleeding reduction. According to the results, when the adding ratio of AE water reducing agent for reduction of bleeding increases, a range of normal fluidity and aimed air content are satisfied, setting time is faster than that of normal AE water reducing agent. And bleeding amount decreases, bleeding speed is highest between 60 and 90 min, and sinking depth increases drastically in 60 min. When. AE water reducing agent for reduction of bleeding is added, compressive strength shows a slight variation by air content, but there is not a large influence by addition of AE water reducing agent for reduction of bleeding. Synthetically, it proves that AE water reducing agent for reduction of bleeding satisfies aimed air content in the range of normal slump and can reduce only bleeding without quality variation of compressive strength.

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Neonatal Coagulation Disorder: Diagnostic Approaches for Bleeding Neonates (신생아 혈액 응고질환: 출혈 경향을 보이는 신생아에 대한 진단적 접근)

  • Kim, Chun-Soo
    • Neonatal Medicine
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    • v.18 no.1
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    • pp.6-13
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    • 2011
  • All newborn infants with clinically significant bleeding should be evaluated for a hemostatic deficit. Medical history should include the following data: familial bleeding disorders, maternal illness and medication, age of bleeding onset, and prophylactic administration of vitamin K. The first essential step for evaluating bleeding neonates is determining whether the baby is sick or well. The physician should also evaluate the extent of the bleeding, features of bleeding lesions, and other abnormal findings from the physical examination. Skeletal anomalies may provide diagnostic clues. Depending on the clinical features and results of screening tests, other tests including coagulation factors may be useful for determining the diagnosis. All laboratory results must be considered in the context of age-related reference values. The platelet function analyzer provides a promising alternative to bleeding time. Fibrin degradation products and D-dimers are used for screening and specially testing fibrinolytic activity, respectively. The Apt test may help to rule out factors derived from maternal blood. Radiologic imaging studies are important because asymptomatic intracranial hemorrhages are common in neonates.

Engineering Properties of Bleeding Reduction of Concrete Using AE Water Reducing Agent for the Type of Bleeding Reduction (블리딩저감형 AE감수제를 사용한 콘크리트의 공학적 특성)

  • Han, Cheon-Goo;Hwang, Yin-Seong;Lee, Seung-Hoon;Kim, Gyu-Dong
    • Journal of the Korea Institute of Building Construction
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    • v.4 no.1
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    • pp.133-140
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    • 2004
  • This study is intended to investigate the properties of bleeding reduction of concrete using AE water reducing agent for the type of bleeding reduction with the replacement admixture. According to the results, when the adding ratio of AE water reducing agent for the type of bleeding reduction increases, a range of normal fluidity and aimed air content are satisfied, setting time is faster than that of normal AE water reducing agent. And bleeding amount decreases, bleeding speed is highest between 60 and 90 min, and sinking depth increases drastically in 50 min. When AE oater reducing agent for the type of bleeding reduction is added, compressive strength shows a slight variation by air content, but there is not a large influence by addition of AE water reducing agent for the type of bleeding reduction. Synthetically, it proves that AE water reducing agent for the type of bleeding reduction satisfies aimed air content in the range of normal slump and can reduce only bleeding without quality variation of compressive strength.

Real-time Bleeding Animation for Virtual Surgery Medical Simulation (가상 수술 의료 시뮬레이션을 위한 실시간 출혈 애니메이션 기법)

  • Lee, Jeong-Jin;Seo, Che-Hwan;Lee, Ho;Kye, Hee-Won;Lee, Min-Sun
    • Journal of Korea Multimedia Society
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    • v.15 no.5
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    • pp.664-671
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    • 2012
  • Recently, practice education using virtual medical simulation has been applied to real clinical environment by enhancing the learning efficiency. Specially, in minimally invasive surgery, the necessity of virtual surgery medical simulation has been increased. Realistic bleeding animation, which represents bleeding special effects frequently occurred in virtual medical simulation environment, has not been proposed yet. In this paper, we propose realistic real-time bleeding animation. For bleeding simulation, proposed method calculates main and effective bleeding regions along the main bleeding direction vector to represent naturalistic bleeding effect. In addition, for bleeding rendering, proposed method uses sigmoid function to impose weights of vertex opacities for the smooth opacity change so that the results of bleeding animation is realistic. Proposed method improves the sense of the real and absorption in virtual surgery medical simulation so that the education efficiency of doctors and students using medical simulation can be enhanced.

Bleeding After Gastric Endoscopic Submucosal Dissection Focused on Management of Xa Inhibitors

  • Ono, Shoko;Ieko, Masahiro;Tanaka, Ikko;Shimoda, Yoshihiko;Ono, Masayoshi;Yamamoto, Keiko;Sakamoto, Naoya
    • Journal of Gastric Cancer
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    • v.22 no.1
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    • pp.47-55
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    • 2022
  • Purpose: The use of direct oral Xa inhibitors (DXaIs) to prevent venothrombotic events is increasing. However, gastrointestinal bleeding, including that related to endoscopic resection, is a concern. In this study, we evaluated bleeding and coagulation times during the perioperative period of gastric endoscopic submucosal dissection (ESD). Materials and Methods: Patients who consecutively underwent gastric ESD from August 2016 to December 2018 were analyzed. Bleeding rates were compared among the 3 groups (antiplatelet, DXaIs, and control). DXaI administration was discontinued on the day of the procedure. Prothrombin time (PT), activated partial thromboplastin time, and the ratio of inhibited thrombin generation (RITG), which was based on dilute PT, were determined before and after ESD. Results: During the study period, 265 gastric ESDs were performed in 239 patients, where 23 and 50 patients received DXaIs and antiplatelets, respectively. Delayed bleeding occurred in 17 patients (7.4%) and 21 lesions (7.1%). The bleeding rate in the DXaI group was significantly higher than that in the other groups (30.4%, P<0.01), and the adjusted odds ratio of bleeding was 5.7 (95% confidence interval, 1.4-23.7; P=0.016). In patients using DXaIs, there was a significant (P=0.046) difference in the median RITG between bleeding cases (18.6%) and non-bleeding cases (3.8%). Conclusions: A one-day cessation of DXaIs was related to a high incidence of bleeding after gastric ESD, and monitoring of residual coagulation activity at trough levels might enable the predicted risk of delayed bleeding in patients using DXaIs.