• Nutrition Research and Practice
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• 제5권4호
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• pp.308-312
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• 2011

This was a prospective cohort study of 976 infants from birth to 12 months of age. Infants were fed breast milk, goat infant formula, cow infant formula, or a combination of formula and breast milk during the first 4 months of age. Data on type of milk feeding and infant growth (weight and height) were collected at birth and at 4, 8, and 12 months during routine clinical assessment. The number and consistency of bowel motions per day were recorded based on observational data supplied by the mothers. Infants fed breast milk or goat or cow infant formula during the first 4 months displayed similar growth outcomes. More of the infants fed cow infant formula had fewer and more well-formed bowel motions compared with breast-fed infants. The stool characteristics of infants fed goat formula resembled those of infants fed breast milk.

• Journal of Preventive Medicine and Public Health
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• 제11권1호
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• pp.24-30
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• 1978

This study was designed to analyse effects of Family Health Workers' activities on the performance of a child immunization program as part of the evaluative research in the community health demonstration project in Kang Wha. Frequent shortcomings of evaluative research are problems in setting evaluative indices, difficulties in interpreting influences of socioeconomic changes due to lack of control and failure of demonstrating association between activity input and program performance. Specific objectives of this study was to improve the frequent shortcoming of evaluative research by isolating the effects of Family Health Workers' activities on the performance of the program through controlling other variables which also influenced the program performance. The target population consisted of 1240 children who were born between Jan. 1971 and Dec. 1975 in Sunwon Myun, and Naega Myun in Kwang Wha Gun, Kyonggi Province. The data were collected in part through 20 Family Health Workers who interviewed the mothers of these children in their villages during Nov. 1977. Part of the data were obtained by summarizing Family Health Workers daily activity records. All data were grouped for each birth cohort according to the 20 villages. Dependent variable of the model is the measle immuinization rate of each village and the independent variables are characteristics of baby, mother, household, travel time to the health subcenter, to Kang Wha Town, and the mean member of visits to the household by Family Health Workers as well as their other related activities and the year of birth of children according to village. The model was analysed by stepwise multiple regression technique. The summarized results show that overall $R^2$ were 39.3% and mean number of Family Health Worker household visits, mean age of mother and mean economic status were significant variables in explaining the immunization rate. Therefore Family Health Workers' activities are one of the significant variables in influencing the increased immunization rate of children in villages of the project area.

• Archives of Plastic Surgery
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• 제45권6호
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• pp.517-524
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• 2018

Background Infantile hemangioma (IH) is a common vascular tumor in pediatric patients, and is commonly treated with propranolol. We describe our experiences with dosage, response to treatment, and side effects in 23 IH patients treated with propranolol. Methods For this nonrandomized comparative cohort study, the authors enrolled 23 patients treated with propranolol. Photographs were taken before propranolol administration and at 3, 6, 9, and 12 months after treatment. Treatment responses were objectively analyzed with a computer program. Results There were three male and 20 female patients. Common tumor locations were the head and neck (13 cases, 56.5%), trunk (four cases, 17.4%), extremities (three cases, 13.0%), and combined locations (three cases, 13.0%). The response to propranolol was significantly lower in patients with two or more lesions than in patients with a single lesion in terms of both color fading (P<0.001) and size reduction (P<0.001). In male patients ($42.2{\pm}3.9$), the change in a-values, indicating coloration, was higher than in female patients ($19.8{\pm}13.8$) (P<0.001). In patients who started treatment before 6 months after birth, the size reduction was greater than in their counterparts (62.3%; range, 3.0%-93.0% vs. 15.8%; range, 1.0%-79.0%; P<0.001). Conclusions Propranolol is an efficacious treatment with a good safety profile. In patients with a single lesion, the response to treatment was better in terms of color fading and size reduction. Furthermore, male patients responded better to propranolol treatment in terms of color fading than female patients, and starting treatment before 6 months after birth was more advantageous for size reduction.

• Asian Pacific Journal of Cancer Prevention
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• 제15권21호
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• pp.9535-9541
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• 2014

Background: Identifying risk factors of breast cancer is a key point for preventive strategies to reduce the incidence. The aim of current study was to determine most important risk factors for breast cancer in the Eastern Mediterranean Region (EMR) using a systematic review. Materials and Methods: PubMed, Scopus, Web of Science till August 24, 2012 and the reference lists of all included studies were searched. Analytic studies which had reported odds ratios (OR), relative risk (RR) or required data to calculate them were included. A total of 343 studies were critically appraised and finally 30 studies were meta-analyzed. Heterogeneity between the studies was assessed by $I^2$ and Cochran's Q. Egger's test was used to assess publication bias. Results: Twenty five casecontrol studies, one nested case-control and four cohort studies were included. The largest ORs were obtained for history of no live birth (2.25; 95%CI: 1.58-3.18), body mass index (BMI) more than 30 (2.21; 95%CI: 1.71-2.36), age at first pregnancy more than 30 years old (1.52; 95%CI: 1.30-1.77) and meat consumption more than three times per week (1.39; 95%CI: 1.03-1.87). The other important predictors were higher education and smoking as risk factors, physical activity and ovulatory stimulating medication as protective factors. Conclusions: The most important predictors of breast cancer in EMR were history of no live birth, BMI more than 30, age at first pregnancy more than 30 years old, physical inactivity and smoking. Almost all these risk factors are consistent with known risk factors for this cancer in other parts of the world.

• Kidney Research and Clinical Practice
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• 제37권4호
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• pp.338-346
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• 2018

Background: The most common cause of acute kidney injury (AKI) in pregnancy is preeclampsia. Serum cystatin C (CysC) is a potential biomarker of early kidney damage as its levels are not disturbed by volume status changes in pregnancy, and serum CysC levels could serve as a replacement for conventionally used creatinine. In this study, we investigated the serum levels of CysC in severe preeclampsia cases and the associations between CysC levels and poor obstetric outcomes. Methods: Our cohort included severe preeclampsia patients with a normal serum creatinine level. Creatinine was measured to calculate estimated glomerular filtration rate (eGFR) based on the Cockcroft and Gault, Modification of Diet in Renal Disease Study (MDRD), and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations, while CysC was measured to calculated eGFR based on a CysC-based equation. We then evaluated the correlations between serum CysC level, eGFR, and obstetric outcomes. Results: Twenty-six patients were evaluated of which 38.5% delivered preterm and 30.8% had low-birth weight babies. Unlike creatinine-based eGFR and CysC-based eGFR, serum CysC demonstrate significant negative correlation with gestational age. Receiver operating characteristic curve analysis indicated that serum CysC is a potential biomarker of preterm delivery with a cut-off serum level of 1.48 mg/L with 80% sensitivity and 75% specificity. Conclusion: GFR estimation using CysC is likely to be inaccurate in pregnancy. However, we found a significant correlation between preterm delivery and serum CysC level. Our results suggest that serum CysC level has the potential to predict preterm delivery in severe preeclampsia patients.

• 사회복지연구
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• 제41권3호
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• pp.349-378
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• 2010

'생애과정 관점' 은 생애과정을 제도와 역사에 내재된 단계화된 연령구조로 인식하고, 맥락적 관점에서 개인과 집단의 생애를 이해하려는 이론적 방향이다. 독일과 미국을 중심으로 사회·역사적 변화의 맥락 속에서 생애과정을 분석하고, 생애과정에 미친 제도와 국가의 역할을 다루는 연구가 이루어졌고, 노동궤적에서 나타나는 경로와 노동성과의 차이, 생애과정에서 나타나는 불평등에 관한 연구 등에서 생애과정 관점이 적용되어 왔다. 국내에서도 다양한 분야에서 생애과정에 관한 연구가 시도되고, 결과가 축적되고 있으나 이론적 방향이나 체계로서 확립되지는 못하였다. 생애과정 관점을 적용하여 개인의 생애과정과 역사적, 사회적 변화를 접목시키는 시도로 1930~1979년 사이에 출생한 코호트의 역사적 위치를 확인하고 성인으로의 이행과정에서 나타난 변화를 추적하였다. 그 결과, 교육기간의 연장으로 인해 후속 이행의 시기와 구조에 변화가 발생하였고, 1960년대 출생코호트까지 젊은 코호트로 올수록 교육종료와 노동시장 진입, 결혼과 첫 출산이 이루어지는 시점이 지연됨과 동시에 대부분의 구성원이 압축된 연령 구간에서 이행을 완료하는 생애과정의 표준화가 이루어졌음이 확인되었다. 1970년대 출생 코호트는 이전 코호트와는 다른 이행패턴을 보이고 있으나 이행시기의 지연으로 구성원의 이행이 완료되지 않은 우측 절단이 발생하여 그 정확한 변화를 확인하지는 못하였다.

• 성인간호학회지
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• 제28권3호
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• pp.288-301
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• 2016

Purpose: The purpose of this study was to identify association between maternal depression and multiple contextual factors in 1,519 mothers in Korea who participated in the 2009 Panel Study of Korean Children (PSKC). Methods: The second wave data which was a comprehensive longitudinal data set with a nationally representative birth cohort was analyzed using SAS 9.3 software. Kessler depression scale was used for this study. Results: Of the mothers, 23.0% reported being mild to moderate depression and 4.5% of the mothers reported severe depression. The factors influencing maternal depression include; mother's self-efficacy, mother's marital conflict, mother's social support, infant's and toddler's emotionality, mother's smoking and infant's feeding & eating of daily routine. These variables explained 39.5% of maternal depression. Conclusion: The results of this study suggest that the identified factors for maternal depression should be included in an intervention program to reduce the risk of depression.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 2002년도 제54차 추계 학술대회 연제집
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• pp.210-211
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• 2002

• 한국생활과학회지
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• 제22권3호
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• pp.405-420
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• 2013

The purpose of this study was to find pathways among factors that distinguish the mothers' intention to have a second child. As for factors affecting the childbirth intention of mothers, this study aimed to explore pathways from fathers' participation in childrearing to intention of second childbirth as mediating variables, maternal parenting stress and marital satisfaction. This study used the third wave data of the Panel Study of Korean Children (PSKC) that is a national-representative birth-cohort study. Among the 1,802 participants of the PSKC, 717 mothers who have a husband/partner and only one child have responded a decided intention of second childbirth. SPSS 19.0 and Amos 19.0 were used to implement exploratory analyses of predictors and test path models. Results showed that the hypothetical model assuming a path from paternal involvement in childrearing to mothers' intention of second childbirth, mediated by maternal parenting stress and marital satisfaction fitted the data of working mothers and non-working mothers well. The results suggest policies focusing on internal characteristics of mothers and dynamics in the family.

• 노동경제논집
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• 제41권3호
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• pp.161-186
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• 2018

1980년대 이후 특허 데이터를 이용한 많은 연구가 있었지만, 특허문서에 나온 기술 개발자의 정보를 이용한 연구는 큰 진전을 이루지 못하였다. 이는 해외 모든 국가의 경우 특허에 기재된 개발자의 이름만으로는 동일인 파악이 어렵기 때문이다. 한국 특허 데이터에 포함된 개발자의 식별번호, 생년, 그리고 성별 정보를 이용하여, 본 연구는 생애주기에서 개발자의 기술개발 생산성이 어떻게 변하는지, 세대별로 생산성의 향상이 있었는지 분석하였다. 앞으로 이 개발자 패널데이터를 이용하여 기술개발의 중요한 요소인 기술인력에 관한 연구가 크게 진전되리라고 기대한다.