• 대한의용생체공학회:의공학회지
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• 제32권4호
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• pp.289-294
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• 2011

Laboratory class is an integral part of biomedical engineering education. Current biomedical engineering curriculum in Korea mostly includes mandatory laboratory classes. Most of the Korean biomedical laboratory classes focus on electrical engineering aspects, while molecular/biological engineering aspects are neglected. Many leading universities in U.S.A. offer a more balanced laboratory class where both electrical engineering aspects and molecular/biological engineering aspects are considered. As a part of an effort to enhance undergraduate biomedical engineering education, a new biomedical engineering laboratory class is proposed to offer a more balanced laboratory learning experience.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1997년도 추계학술대회
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• pp.168-171
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• 1997

The purpose of this study is the development of PBL(problem-based learning) system using visual C++5.0 as a window-based application program. A patient who complains of weight loss was used in PBL case. Initial frame is made by dialog-based in MFC(microsoft foundation class). Also, sample medical images are composed of ultra-sound, chest PA, Thyroid scan, otherwise. we will make this program as CD-ROM and the internet application or computer assisted learning and continuous medical education.

• International Journal of Control, Automation, and Systems
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• 제6권6호
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• pp.828-835
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• 2008

We present a novel method for eye location by means of a two-level classifier scheme. Locating the eye by machine-inspection of an image or video is an important problem for Computer Vision and is of particular value to applications in biomedical imaging. Our method aims to overcome the significant challenge of an eye-location that is able to maintain high accuracy by disregarding highly variable changes in the environment. A first level of computational analysis processes this image context. This is followed by object detection by means of a two-class discrimination classifier(second algorithmic level).We have tested our eye location system using FERET and BioID database. We compare the performance of two-level classifier with that of non-level classifier, and found it's better performance.

• 대한치과교정학회지
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• 제51권6호
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• pp.407-418
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• 2021

Objective: To investigate differences in the heritability of skeletodental characteristics between twin pairs with skeletal Class I and Class II malocclusions. Methods: Forty Korean adult twin pairs were divided into Class I (C-I) group (0° ≤ angle between point A, nasion, and point B [ANB]) ≤ 4°; mean age, 40.7 years) and Class II (C-II) group (ANB > 4°; mean age, 43.0 years). Each group comprised 14 monozygotic and 6 dizygotic twin pairs. Thirty-three cephalometric variables were measured using lateral cephalograms and were categorized as the anteroposterior, vertical, dental, mandible, and cranial base characteristics. The ACE model was used to calculate heritability (A > 0.7, high heritability). Thereafter, principal component analysis (PCA) was performed. Results: Twin pairs in C-I group exhibited high heritability values in the facial anteroposterior characteristics, inclination of the maxillary and mandibular incisors, mandibular body length, and cranial base angles. Twin pairs in C-II group showed high heritability values in vertical facial height, ramus height, effective mandibular length, and cranial base length. PCA extracted eight components with 88.3% in the C-I group and seven components with 91.0% cumulative explanation in the C-II group. Conclusions: Differences in the heritability of skeletodental characteristics between twin pairs with skeletal Class I and II malocclusions might provide valuable information for growth prediction and treatment planning.

• 대한의용생체공학회:의공학회지
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• 제30권1호
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• pp.1-9
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• 2009

Many types of small animal imaging modalities, like micro-CT, micro-PET, and micro-SPECT, have been recently developed worldwide. Small animal imaging systems are now recognized as indispensable tools to validate efficacy and safety of new drugs or new therapeutic methods using the animal disease models. With increasing demands for small animal imaging in biomedical research, multimodal small animal imaging systems, like micro-PET/CT or micro PET/MRI, are now also being developed. Small animal imaging with spatial resolution and sensitivity comparable to human imaging is quite challenging since laboratory small animals are much smaller than human beings. Research activities in Korea on small animal imaging systems are reviewed in this paper. In the field of micro-CT and micro-PET, many world-class technologies have been developed successfully in Korea. It is expected that the developed animal imaging system technologies can be used in the development of clinical imaging systems in Korea in the near future.

• Genomics & Informatics
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• 제18권3호
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• pp.33.1-33.7
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• 2020

This paper describes a community effort to improve earlier versions of the full-text corpus of Genomics & Informatics by semi-automatically detecting and correcting PDF-to-text conversion errors and optical character recognition errors during the first hackathon of Genomics & Informatics Annotation Hackathon (GIAH) event. Extracting text from multi-column biomedical documents such as Genomics & Informatics is known to be notoriously difficult. The hackathon was piloted as part of a coding competition of the ELTEC College of Engineering at Ewha Womans University in order to enable researchers and students to create or annotate their own versions of the Genomics & Informatics corpus, to gain and create knowledge about corpus linguistics, and simultaneously to acquire tangible and transferable skills. The proposed projects during the hackathon harness an internal database containing different versions of the corpus and annotations.

• 대한치과교정학회지
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• 제54권2호
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• pp.79-88
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• 2024

Objective: Alveolar bone loss is a common adverse effect of intrusion treatment. Mandibular incisors are prone to dehiscence and fenestrations as they suffer from thinner alveolar bone thickness. Methods: Thirty skeletal class II patients treated with mandibular intrusion arch therapy were included in this study. Lateral cephalograms and cone-beam computed tomography images were taken before treatment (T1) and immediately after intrusion arch removal (T2) to evaluate the tooth displacement and the alveolar bone changes. Pearson's and Spearman's correlation was used to identify risk factors of alveolar bone loss during the intrusion treatment. Results: Deep overbite was successfully corrected (P < 0.05), accompanied by mandibular incisor proclination (P < 0.05). There were no statistically significant change in the true incisor intrusion (P > 0.05). The labial and lingual vertical alveolar bone levels showed a significant decrease (P < 0.05). The alveolar bone is thinning in the labial crestal area and lingual apical area (P < 0.05); accompanied by thickening in the labial apical area (P < 0.05). Proclined incisors, non-extraction treatment, and increased A point-nasion-B point (ANB) degree were positively correlated with alveolar bone loss. Conclusions: While the mandibular intrusion arch effectively corrected the deep overbite, it did cause some unwanted incisor labial tipping/flaring. During the intrusion treatment, the alveolar bone underwent corresponding changes, which was thinning in the labial crestal area and thickening in the labial apical area vice versa. And increased axis change of incisors, non-extraction treatment, and increased ANB were identified as risk factors for alveolar bone loss in patients with mandibular intrusion therapy.