• The Journal of Korean Academic Society of Nursing Education
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• v.24 no.3
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• pp.300-310
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• 2018

Purpose: This study was conducted to investigate the differences of the Code of Ethics, level of application of the Code of Ethics and consciousness of biomedical ethics of nurses about clinical practice experience, ethical values and biomedical ethics education experience of nursing students. Methods: A descriptive research design, t-test and one-way ANOVA were used. The data were collected 1st June to 31st August 2016 from two large cities. The participants were 246 nursing students with a mean age of 22.57 years. Among them, 209 (84.6%) were female, 94 (38.2%) had clinical practice experience, 155 (63.0%) listed their ethical value as different depending on the situation, and 127 (51.6%) had biomedical ethics education experience. Results: The scores were: awareness of the Code of Ethics of Nurses $4.29{\pm}0.60$; application of the Code of Ethics of Nurses $4.24{\pm}0.6$4; and consciousness of biomedical ethics $2.91{\pm}0.19$. There were significant differences in application of the Code of Ethics of Nurses (t=-1.97, p=.050); consciousness of biomedical ethics (t=-2.25, p=.025) related to clinical practice experience; and consciousness of biomedical ethics related to biomedical education experience (t=2.67, p=.007). Conclusion: Clinical practice and biomedical ethics education experience contributed to enhance the level of application of the Code of Ethics of Nurses and consciousness of biomedical ethics of nursing students.

• Journal of Biomedical Engineering Research
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• v.35 no.5
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• pp.111-118
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• 2014

As assessment of quantitative energy expenditure for effective exercise is becoming more important, many researches about the monitoring system for exercise status or result have been actively carried out. In this case, however, bicycle riders feel restrained and uncomfortable because the riders should wear a belt-type electrocardiograph or a watch-type accelerometer or GPS system during the assessment of bicycle exercise. In this study, therefore, an electrocardiograph based on textile electrode was developed for measuring ECG and calculating heart rate from the bicycle rider without feeling restraint, and smartphone application was also developed for monitoring the heart rate.

• Journal of Sensor Science and Technology
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• v.21 no.5
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• pp.367-373
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• 2012

We fabricated a fiber-optic alpha/beta detector, which is composed of a sensing probe, a plastic optical fiber, a photomultiplier tube, and a multichannel analyzer, to obtain the energy spectra of radioactive isotopes. As inorganic scintillators of a sensing probe, a ZnS(Ag) film was coupled with a $CaF_2$(Eu) crystal for alpha and beta spectroscopy. In this study, $^{210}Po$ and $^{90}Sr$ were used as alpha and beta sources, respectively, and we measured the radiation energy spectra using a fiber-optic alpha/beta detector to identify alpha and beta emitting radionuclides for nuclear medicine application. Also, the variations of energy spectrum were obtained according to the length of plastic optical fiber.

• Journal of Electrical Engineering and Technology
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• v.7 no.3
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• pp.451-458
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• 2012

The voluntary EMG (vEMG) signal from electrically stimulated muscle is very useful for feedback control in functional electrical stimulation. However, the recorded EMG signal from surface electrodes has unwanted stimulation artifact and M-wave as well as vEMG. Here, we propose an event-synchronous adaptive digital filter for the suppression of stimulation artifact and M-wave in this application. The proposed method requires a simple experimental setup that does not require extra hardware connections to obtain the reference signals of adaptive digital filter. For evaluating the efficiency of this proposed method, the filter was tested and compared with a least square (LS) algorithm using previously measured data. We conclude that the cancellation of both primary and residual stimulation artifacts is enhanced with an event-synchronous adaptive digital filter and shows promise for clinical application to rehabilitate paretic limbs. Moreover because this algorithm is far simpler than the LS algorithm, it is portable and ready for real-time application.

• Journal of Marine Bioscience and Biotechnology
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• v.13 no.1
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• pp.28-47
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• 2021

Pectin is a natural polysaccharide and biopolymer that serves as a structural component of plant tissues' primary cell walls. Pectin is primarily composed of D-galacturonic acid linked by α-1, 4-glycosidic linkage and is further classified by the ratio of esterified galacturonic acid groups known as degree of esterification (DE). Pectin that contains more than half of its carboxylate units as methyl esters is known as a high methyl (HM) ester. Conversely, pectin that has less than half of its carboxylate units as methyl esters is known as a low methyl (LM) ester. Pectin has various bioactive properties, including anticancer, anti-inflammatory, antioxidant, antidiabetic, anticholesterol, antitumoral, and chemopreventive properties. Moreover, pectin is a useful biopolymer in biomedical applications. Biomedical engineering, which is founded on research aimed to improve the quality of life using new materials and technologies, is typically classified according to the use of hydrogels, nanofiber mats, and nanoparticles. This paper reviews the progress of recent research into pectin-based biomedical applications and the potential future biomedical applications of marine-derived pectin.

• The Korean Journal of Physiology and Pharmacology
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• v.22 no.5
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• pp.547-554
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• 2018

Itching is a common clinical symptom of skin disease that significantly affects a patient's quality of life. Transient receptor potential vanilloid 1 (TRPV1) receptors of keratinocytes and peripheral nerve fibers in skin are involved in the regulation of itching as well as pain. In this study, we investigated whether curcumin, which acts on TRPV1 receptors, affects histamine-induced itching in mice, using behavioral tests and electrophysiological approaches. We found that histamine-induced itching was blocked by topical application of curcumin in a concentration-dependent manner. In ex-vivo recordings, histamine-induced discharges of peripheral nerves were reduced by the application of curcumin, indicating that curcumin acts directly on peripheral nerves. Additionally, curcumin blocked the histamine-induced inward current via activation of TRPV1 (curcumin $IC_{50}=523nM$). However, it did not alter chloroquine-induced itching behavior in mice, which is associated with transient receptor potential ankyrin 1 (TRPA1). Taken together, our results suggest that histamine-induced itching can be blocked by topical application of curcumin through the inhibitory action of curcumin on TRPV1 receptors in peripheral nerves.

• Journal of Korea Multimedia Society
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• v.19 no.8
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• pp.1538-1543
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• 2016

Strabismus is a non-aligned state;the visual axis of each eye is not directed toward the same direction at the same time. Clinically, the degrees of strabismus are measured by prism cover test, corneal reflex test (Hirschberg test), prism reflex test (Krimsky prism test), But corneal reflex test and prism reflex test is a possibility that errors occur. we suggest a computer-aided diagnosis for strabismus. We made a mobile application to measure angles of strabismus. For 34 patients, we tested our application. The result of comparing between two methods, It showed a difference 7 Prism Diopter(PD). Our application gives strabismus angles just using a camera and a smart device. Therefore, it can reduce the cost and make the diagnosis of strabismus accurate.

• The Journal of Korean Academic Society of Nursing Education
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• v.24 no.3
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• pp.214-224
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• 2018

Purpose: This study examines the effectiveness of an educational program of nursing biomedical ethics for nursing students to increase awareness of the Code of Ethics for Nurses, moral sensitivity, and application of the Code of Ethics for Nurses. Methods: A quasi-experimental research design and t-test were used. The experimental group (n=31) and control group (n=32) were second-year university nursing students in two major cities. The experimental group received 15 hours of nursing ethics education during the 15-week semester. The training was not provided to the control group. Results: The application of the Code of Ethics for Nurses increased significantly in the experimental group (t=-1.06, p=.017), nurses and patient (t=-2.23, p=.029), obligation of nurse as an expert (t=-2.08, p=.042), nurse and cooperator (t=-2.54, p=.014). The consciousness of biomedical ethics increased significantly in the experimental group (t=4.28, p=.021), newborn's right to live (t=-2.61, p=.011), euthanasia (t=-2.36, p=.021). Conclusion: The results of the study show that providing a nursing biomedical ethics program to nursing students is an effective method to enhance the application of the Code of Ethics for Nurses and Consciousness of Biomedical Ethics. Implementing an intervention program of the Code of Ethics for Nurses in the regular nursing curriculum may reduce conflicts involving ethical decision making by nurses.

• Journal of Biomedical Engineering Research
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• v.26 no.5
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• pp.331-335
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• 2005

The fusion technology of small sensor and wireless communication was followed by various application examples of the embedded system, where the social infrastructural facilities and ecological environment were wirelessly monitored. In addition, this technology represents the primary application area being extended into the healthcare field. In this study, a body area network for ubiquitous healthcare is presented. More specifically this represents a wireless biomedical signal acquisition device characterized by small size, low power consumption, pre-processing and archiving capability. Using this device, a new method for monitoring vital signs and activity is created. A PDA-based wireless sensor network enables patients to be monitored during their daily living, without any constraints. Therefore, the proposed method can be used to develop Activities of Daily Living (ADL) monitoring devices for the elderly or movement impaired people. A medical center would be able to remotely monitor the current state of elderly people and support first-aid in emergency cases. In addition, this method will reduce medical costs in society, where the average life expectancy is increasing.

• Journal of Biomedical Engineering Research
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• v.14 no.3
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• pp.209-220
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• 1993

Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, Immunomagnetic cell separation. To synthesize micro-spheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio or synthesized microspheres was always smatter than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6-13 times higher than thats of the ml crospheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin Is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption Isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin ) . The effect of the kind and the amount of surface functional group was also examined.p was also examined.