• Title/Summary/Keyword: biological stability

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Plasma Cosmetic Container Suitability (플라즈마 화장품 용기 적합성)

  • Ha Hyeon Jo;You-Yeon Chun;Hyojin Heo;Sang Hun Lee;Lei Lei;Ye Ji Kim;Byeong-Mun Kwak;Mi-Gi Lee;Bum-Ho Bin
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.50 no.1
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    • pp.59-65
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    • 2024
  • For plasma cosmetics, it is important to ensure the long-term stability of plasma in the formulation. This study examined the suitability of containers for efficient plasma cosmetics development. By varying the surface area covered by the plasma, 4 cm2, 25 cm2, 75 cm2, and 175 cm2 containers were injected with cosmetic plasma, and the amount of nitric oxide (NO), the main active species of nitrogen plasma, was analyzed. As a result, the surface area and stability exposed to plasma tended to be inversely proportional, and it was most effective in a 4 cm2 container. Furthermore, 25 mm, 40 mm, and 50 mm vials were treated with plasma, which resulted in relative long-term stability of NO at 25 mm, a smaller surface area of the container exposed to air. Water mist and stratified mist were selected as cosmetic formulations, and NO plasma was injected into the water layer to observe the changes in formulation properties and the state of the injected NO plasma. In both formulations, the amount of NO plasma injected was about 1.5 times higher in the water phase mist than in the stratified mist, and the stratified mist gradually decreased with time and was found to disappear after 3 weeks. The stability of the nitrogen plasma was studied at low temperature (4 ℃), room temperature (25 ℃), and high temperature (37 ℃, 50 ℃). As a result, it was found that the water mist did not affect the stability, but the stratified mist observed a color change in the oil phase layer. Overall, this study demonstrates the container suitability of nitrogen plasma and suggests the importance of ensuring the stability of injected nitrogen plasma in cosmetic formulations.

Enzymatic Chillproofing and Beer Foam Stability- Part 1. Foam Deterioration during Manufacturing Processes (효소에 의한 제탁조작과 맥주의 발포성 제I보. 제조공정중의 발포성상실)

  • Pack, M.Y.
    • Microbiology and Biotechnology Letters
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    • v.3 no.2
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    • pp.83-87
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    • 1975
  • An excellent foam stability in the freshly fermented green beer of a commercial brewery was found to be destroyed substantially by the time it was finished. A further survey proved that the processes of aging and pasteurization accompanied by enzymatic chillproofing were responsible for the foam deterioration.

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Human $\alpha_1$-Antitrypsin Variant with Enhanced Conformational Stability at the Cost of Activity

  • Seo, Eun-Joo;Hana Im;Yu, Myeong-Hee
    • Proceedings of the Korean Biophysical Society Conference
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    • 1997.07a
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    • pp.39-39
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    • 1997
  • Native strain of inhibitory SERPINS (Serine protease inhibitors) is thought to be used in the facile conformational switch to play biological regulation. Many heat stable variants of $\alpha$$_1$-antitrypsin, a prototype of inhibitory serpins, increased their stability by reducing the native strain.(omitted)

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Stability of the current biological drugs(typhoid vaccine)

  • Lee, Joo-Hyeun;Ham, Myung-Hwa;Lim, So-Hee;Lee, Gil-Woong
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.328.2-328.2
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    • 2002
  • This paper presents stability of tyhoid vaccine -attenuuated vaccine(oral) and killed vaccine{vi polysaccharide)- 5 classes with various temperature(3 points: iced temperature, refrigeration temp.. indoor temp.). Analytical techniques -vi polysaccharide content. pH. sterility. assay - have been used for the quantity of pharmacologically active chemical entries. From this study. we have found the attenuated vaccine is show iced temp. 258% and indoor temp. 0.02% compare with refrigeration temp. in assay examination and the killed vaccine is not found different. (omitted)

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Urokinase Conjugated with Water-Soluble Dextran

  • Kim Nam Deuk;Kim Hyun-Pyo;Byun Si Myung;Kim Sung Wan
    • Bulletin of the Korean Chemical Society
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    • v.6 no.4
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    • pp.210-214
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    • 1985
  • Urokinase, a plasminogen activator, was conjugated with dextran by the cyanogen bromide activation-coupling method. The resulting water-soluble conjugate was purified by gel permeation chromatography on Sephadex G-200. The maximal activity was obtained when the ratio of urokinase/dextran was 1/20 for the coupling. The final preparation showed 5 CTA units/mg conjugate, 300 CTA units/mg protein, 8.4 % activity retention, and 47 % protein retention. The urokinase-dextran conjugate had good thermal, pH and storage stabilities. In addition, it showed greater resistance to the inhibitory effect of human plasma than native urokinase. Also in vitro biological half-life of urokinase increased 40 times by this conjugation. In view of activity, excellent stability and increased half-life, the conjugate can be a potential fibrinolytic agent in an injectable form.

Biological stability in the ozone and peroxone pretreatment systems in river water (하천수 내 생물학적 안정성에 따른 유기물 특성변화와 오존산화기반 전처리 연구)

  • Park, Se-Hee;Noh, Jin-Hyung;Park, Ji-Won;Maeng, Sung-Kyu
    • Journal of Korean Society of Water and Wastewater
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    • v.32 no.2
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    • pp.159-168
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    • 2018
  • Climate change is believed to increase the amount of dissolved organic matter in surface water, as a result of the release of bulk organic matter, which make difficult to achieve a high quality of drinking water via conventional water treatment techniques. Therefore, the natural water treatment techniques, such as managed aquifer recharge (MAR), can be proposed as a alternative method to improve water quality greatly. Removal of bulk organic matter using managed aquifer recharge system is mainly achieved by biodegradation. Biodegradable dissolved organic carbon (BDOC) and assimilable organic carbon (AOC) can be used as water quality indicators for biological stability of drinking water. In this study, we compared the change of BDOC and AOC with respect to pretreatment methods (i.e., ozone or peroxone). The oxidative pretreatment can transform the recalcitrant organic matter into readily biodegradable one (i.e., BDOC and AOC). We also investigated the differences of organic matter characteristics between BDOC and AOC. We observed the decreases in dissolved organic carbon (DOC) and the tryptophan-like fluorescence intensities. Liquid chromatographic - organic carbon detection (LC-OCD) analysis also showed the reduction of the low molecular weight (LMW) fraction (15% removed, less than 500 Da), which is known to be easily biodegradable, and the biopolymers, high molecular weight fractions (66%). Therefore, BDOC consists of a broad range of organic matter characteristics with respect to molecular weight. In AOC, low molecular weight organic matter and biopolymers fraction was reduced by 11 and 6%, respectively. It confirmed that biodegradation by microorganisms as the main removal mechanism in AOC, while BDOC has biodegradation by microorganism as well as the sorption effects from the sand. $O_3$ and $O_3+H_2O_2$ were compared with respect to biological stability and dissolved organic matter characteristics. BDOC and AOC were determined to be about 1.9 times for $O_3$ and about 1.4 times for $O_3+H_2O_2$. It was confirmed that $O_3$ enhanced the biodegradability by increasing LMW dissolved organic matter.

Effect of MeOH/IPA Ratio on Coating and Fluxing of Organic Solderability Preservatives (유기 솔더 보존제의 코팅 및 플럭싱에 대한 메탄올/이소프로필알콜 비율의 영향)

  • Lee, Jae-Won;Kim, Chang Hyeon;Lee, Hyo Soo;Huh, Kang Moo;Lee, Chang Soo;Choi, Ho Suk
    • Korean Chemical Engineering Research
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    • v.46 no.2
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    • pp.402-407
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    • 2008
  • Recent popularity in mobile electronics requires higher standard on the mechanical strength of electronic packaging. Thus, the method of soldering between chip and substrate in electronic packaging process is changing from conventional method using intermetallic compound to a new method using organic solderability preservative (OSP) in order to improve the stability and the reliability of final product. Since current organic solder preservatives have several serious problems like thermo-stability during packaging process, however, it is necessary to develop new OSPs having thermo-stability. The main purpose of this study is to investigate the effect of MeOH/IPA (Isopropyl alcohol) ratio on the fluxing of a new OSP, developed in previous research, andto find out an optimum formulation of flux components for the application of the OSP in current packaging process. As a result of this study, it was revealed that higher MeOH/IPA ratio in flux showed better performance of fluxing a new OSP.

Improvement of Dimensional Stability of Acacia mangium Wood by Heat Treatment: A Case Study of Vietnam

  • Tran, Van Chu
    • Journal of Forest and Environmental Science
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    • v.29 no.2
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    • pp.109-115
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    • 2013
  • Fast-grown wood generally contains a high proportion of juvenile wood that results in inferior dimensional stability and durability against biological deteriorations. In the present research, the Acacia mangium wood from plantation forests in Vietnam was treated with high temperature in air. The effects of heat treatment on physical properties of Acacia mangium wood, including mass loss (ML), water absorption (WA), water-repellent effectiveness (WRE) and anti-swelling efficiency (ASE) were examined. The results showed that the dimensional stability and the water-repellent effectiveness are increased by about 15-46% and 8-18%, respectively. However, the mass and dimension of wood are decreased. The results also indicated that both treatment temperature and treatment duration significantly affect the wood properties of Acacia mangium. It is thus concluded that heat treatment demonstrates an interesting potential to improve the wood quality of Acacia mangium for solid timber products. This technology provides an environmentally safe method of protecting sustainable common woods to give a new generation of value-added biomaterials with increased stability without the use of toxic chemicals.

Community changes in carabid beetles (Coleoptera: Carabidae) through ecological succession in abandoned paddy fields

  • Do, Yu-No;Jeong, Kwang-Seuk;Lineman, Maurice;Kim, Ji-Yoon;Kim, Hang-Ah;Joo, Gea-Jae
    • Journal of Ecology and Environment
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    • v.34 no.3
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    • pp.269-278
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    • 2011
  • Carabid beetle community changes in paddy fields, abandoned paddy fields, and mountains were investigated to understand differences in species diversity and composition of different habitat types in small agricultural landscapes in South Korea. A total of 2,938 individuals from 37 species were identified and classified from the studied habitats. Diversity in the mountains was higher than that in abandoned paddy fields. As the number of years since abandonment increased, the diversity and stability of the carabid beetle community also increased. Abandoned paddy fields in some paddy field areas and adjoining mountainous areas, left with preconditions for management and control, have provided the opportunity to improve the diversity and habitat of small agricultural landscapes. Species composition changed continuously from the paddy fields to the mountains, in accordance with individual species habitat preferences. Abandoned paddy fields in small agricultural landscapes are believed to play an important role as transitional buffer zones between paddy fields and the adjacent mountainous areas.