• 한국균학회소식:학술대회논문집
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• 2015.05a
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• pp.20-20
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• 2015

Endophytic fungi are microorganisms inhabiting living plant tissues without causing apparent harm to the host. They are drawing increasing attention due to their ability to produce various bioactive compounds as well as their effects on host growth and resistance to biotic and abiotic stresses. As a first step to assess biodiversity of plant associated fungi in Korea and the following evaluation on diverse biological activities, we are collecting endophytic fungi from plant in wild followed by systematic long-term storage in liquid nitrogen. Molecular identification using ITS sequences was also incorporated for pure culture by hyphal tip isolation. As of April 2015, about 1,400 fungal strains had been isolated from about 170 plant taxa. Fungal isolates belonging to Pleosporales, Diaporthales, Glomerellales, Hypocreales, and Xylariales were the most abundant. These collections are being used for several complementary researches, including screening of isolates with novel bioactive compounds or conferring drought stress resistance, phylogenetic and genomic study. Genome sequencing was performed for 3 isolates, one Xylaria sp. strain JS573 producing griseofulvin, an antifungal compound, and two Fusarium spp. strains JS626 and JS1030, which are assumed to be new species found in Korea. More detailed analysis on these genomes will be presented. These collections and genome informations will serve as invaluable resources for identifying novel bioactive materials in addition to expand our knowledge on fungal biodiversity.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.64-67
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• 1997

In the total artificial heart(TAH), a transcutaneous information transmission system(TITS) is vely important to monitor the TAH status and detect the device failure, and repair the possible problems. First of all, the communication channel(skin) and method were simulated in terms of transmittance, scattering, reflection and absorption, then the system was designed with size reduction including low power consumption and reliability compared to the previous one. The informations are transmitted through the skin(approximately 1cm in depth) by frequency modulated near infrared(NIR) pulses using 780nm laser diodes as transmitters and photodiode as receiver with high speed and high spectral sensitivity. The logic high and low frequencies are 3MHz, 1MHz respectively. The system is a bidirectional data link for more than 38.4Kbps data rate, full-duplex with a bit error rate of less than $10^{-5}$.

• Korean Journal of Biological Psychiatry
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• v.6 no.1
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• pp.49-66
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• 1999

Polypharmacotherapy, both psychotropic and nonpsychotropic, is widespread in various situations including psychiatric hospitals and general hospitals. As the clinical practice of using more than one drug at a time increase, the clinician is faced with ever-increasing number of potential drug interactions. Although many interactions have little clinical significances, some may interfere with treatment or even be life-threatening. The objective of this review is evaluation for drug-drug interactions often encountered in psychiatric consultation. Drug interactions can be grouped into two principal subdivisions : pharmacokinetic and pharmacodynamic. These subgroups serve to focus attention on possible sites of interaction as a drug moves from the site of administration and absorption to its site of action. Pharmacokinetic processes are those that include transport to and from the receptor site and consist of absorption, distribution on body tissue, plasma protein binding, metabolism, and excretion. Pharmacodynamic interactions occur at biologically active sites. In psychiatric consultation, these two subdivisions of drug interactions between psychotropic drugs and other drugs are likely to happen. We gathered informations of the drugs used in physically ill patients who are consulted to psychiatric department in Korea University Hospital. And we reviewed the related literatures about the drug-drug interactions between psychotropic drugs and other drugs.

• Applied Microscopy
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• v.43 no.2
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• pp.65-74
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• 2013

Although the geometrical difference in body position between web-building and wandering spiders could affect the organization of their central nervous system (CNS), however most of our informations about spider's CNS are dependent on those revealed from the wandering spiders. Therefore, this paper describes microstructural organizations of the CNS in the geometric orb-web spider Araneus ventricosus. Similarly to other wandering spiders, the CNS of A. ventricosus is also consisted of a dorsal supraesophageal ganglion and a ventral subesophageal mass. The supraesophageal ganglia are fused together and made up of a large sized nerve cell clusters, whereas the subesophageal ganglia are made up of the foremost part of the ventral nerve cord. It has been revealed that the only nerve arising from the supraesophageal mass was the optic nerve which connected with four pairs of eyes, whereas a pair of pedipalpal and four pairs of appendage nerves including abdominal nerve pairs were arisen from the subesophageal nerve mass. Fibrous masses are highly organized into longitudinal and transverse tracts, and are only consisted of processes of neurons and the terminal ramnifications of peripheral sensory neurons. In addition, central fibrous mass of both the brain and the subesophageal mass are totally devoid of nerve cell bodies.

• Journal of Ecology and Environment
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• v.38 no.4
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• pp.563-598
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• 2015

A floristic study on the diatom was carried out in coastal area at two seasons, August 2014 and April 2015, from three islands in the northern area of Yellow Sea of South Korea. A total of 117 species of diatoms, including 3 classes, 9 subclasses, 20 orders, 32 families and 54 genera, were identified based on LM and SEM examinations. Three species of diatoms, Gyrosigma obscurum, Pleurosigma frenguellianum, and P. sabangi were newly recorded in Korea. The historical synonyms of the species are presented for the floristic informations, the examined specimen for the each taxon is specified, and the distribution in three islands and detailed sampling localities of each taxon are given.

• Journal of Biomedical Engineering Research
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• v.14 no.4
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• pp.355-364
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• 1993

Clinical laboratory order communication system was developed to run fast and effective laboratory tests at the Chungbuk National University Hospital. The present system incorporated with the main Hospital Management Information System accepts :aboratory orders, classifies them based on the predefined logical system, and outputs various practical informations for the user. These assist sample taking, sample management, and work plan organization. A special care was taken to the sample management by introducing the bar code system. The system was written in the INFOS hierarchical database and COBOL, and is currently in the practical use for both in - and out-ward patients. The present system enabled fast and effective data communication as well as reducing the time and man power indispensable when the manual slips are used for order communication.

• Journal of Biomedical Engineering Research
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• v.26 no.5
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• pp.271-282
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• 2005

There are strong demands for accurate, fast, and inexpensive devices in the medical diagnostic laboratories, such as biosensors and chemical sensors. Biosensors can provide the reliable and accurate informations on the desired biochemical parameters, which is an essential prerequisite for a patient before going for a treatment. They can be used for continuous measurements of metabolites, blood cations, gases, etc. Of these, electrochemical biosensors play an important role in the improvement of public health, because rapid detection, high sensitivity, small size, and specificity are achievable for clinical diagnostics. In this paper, the clinical applications with electrochemical biosensors are reviewed. An attempt is also made to highlight some of the trends that govern the research and developments of the important biosensors that are associated to clinical diagnosis.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.22 no.4
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• pp.98-103
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• 1986

The passive acoustic system only has generally used in fish detection. But the passive acoustic system has not been tried in fishing since Freytag has proposed a possibilities of the passive detection of fishes in 1963. This paper describes the .feasible aspects of fish detection by listening of the sound they make. The passive acoustic system accompanied the active acoustic system may expand the range of detection and compensate for lack of capabilities each other, but there are some difficulties in noise rejection because the fre9uency range of ship noises covers the whole range vf biological sounds. The attempt to collect useful informations from underwater would be greatly contributed in fisheries.

• Journal of Biomedical Engineering Research
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• v.15 no.1
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• pp.63-70
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• 1994

A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors'reporting results. Input int'ormation was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and Analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed id'ormation can be transferred for patient diagnosis through LAN (local area network).

• Proceedings of the KOSOMBE Conference
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• v.1998 no.11
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• pp.129-130
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• 1998

In this paper, We designed the ECG-NIBP-$SpO_2$ patient monitor. This production can measure Electrocardiograph, Heart Rate, Noninvasive Blood Pressure, and Oxygen Saturation for Noninvasive Mehod and can display each information. These informations were implemented by the electrodes of ECG part, the cuff of NIBP module and the finger probe with light sensor of $SpO_2$ without injection of needle or catheter. In addition, We developed a new analysis algorithm and measurement technique for NIBP and $SpO_2$ to observe patient's conditions correctly.