• Title/Summary/Keyword: biological information objects

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A Study on Design and Analysis of Method for MR-based 3D Biological Object Recognition and Matching (MR 기반 3차원 생체 객체 인식 및 정합을 위한 방법 설계와 해석 연구)

  • Jin-Pyo Jo;Yong-Bae Jeong
    • Journal of Platform Technology
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    • v.12 no.2
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    • pp.23-33
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    • 2024
  • The development of mixed reality (MR) technology has a great influence on the research and development of medical support equipment. In particular, it supports to respond effectively to emergencies occurring in the field. MR technology enables access to first aid and field support by combining virtual information with the real world so that users can see virtual objects in the real world. However, due to the nature of the equipment, there is a limitation in accurately matching virtual objects based on user vision. To improve these limitations, this paper proposes a 3D biometric object recognition and matching algorithm in the MR environment. As a result of the experiment, when a virtual object is rendered and visualized while equipped with an optical-based HMD from the user's side, it was possible to reduce the user's field of view error and eliminate the joint-loss phenomenon during skeleton recognition. The proposed method can reduce errors between the real user's field of view and the virtual image and provide a basis for reducing errors that occur in the process of virtual object recognition and matching. It is expected that this study will contribute to improving the accuracy of the telemedicine support system for first aid.

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Xenie: Integration of Human 'gene to function'information in human readable & machine usable way

  • Ahn, Tae-Jin
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2000.11a
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    • pp.53-55
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    • 2000
  • Xenie is the JAVA application software that integrates and represents 'gene to function'information of human gene. Xenie extracts data from several heterogeneous molecular biology databases and provides integrated information in human readable and machine usable way. We defined 7 semantic frame classes (Gene, Transcript, Polypeptide, Protein_complex, Isotype, Functional_object, and Cell) as a common schema for storing and integrating gene to function information and relationship. Each of 7 semantic frame classes has data fields that are supposed to store biological data like gene symbol, disease information, cofactors, and inhibitors, etc. By using these semantic classes, Xenie can show how many transcripts and polypeptide has been known and what the function of gene products is in General. In detail, Xenie provides functional information of given human gene in the fields of semantic objects that are storing integrated data from several databases (Brenda, GDB, Genecards, HGMD, HUGO, LocusLink, OMIM, PIR, and SWISS-PROT). Although Xenie provide fully readable form of XML document for human researchers, the main goal of Xenie system is providing integrated data for other bioinformatic application softwares. Technically, Xenie provides two kinds of output format. One is JAVA persistent object, the other is XML document, both of them have been known as the most favorite solution for data exchange. Additionally, UML designs of Xenie and DTD for 7 semantic frame classes are available for easy data binding to other bioinformatic application systems. Hopefully, Xenie's output can provide more detailed and integrated information in several bioinformatic systems like Gene chip, 2D gel, biopathway related systems. Furthermore, through data integration, Xenie can also make a way for other bioiformatic systems to ask 'function based query'that was originally impossible to be answered because of separatly stored data in heterogeneous databases.

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The Direction for Development of Domestic Initial Response System for Chemical Terrorism (국내 화학테러 초기대응체제의 발전방향 (한·미 화학테러 초기대응체제 비교를 중심으로))

  • Eun, Chong-hwa
    • Journal of the Society of Disaster Information
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    • v.5 no.2
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    • pp.50-73
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    • 2009
  • This paper is about the establishment of "Initial Response System." Initial response system is most important and should be treated urgently among all preparations for chemical terrorism. The objects of Initial response system are to protect civilians and the first responder who are exposed directly to chemical terrorism. Therefore, this paper suggests two main issues about Initial response system. One is to prepare immediate and exact information service system which assures the safety and survival of exposed people. The other is to build Scene Response System integrated with Command-Control Procedure for early finished situation. Compared to United States, overcoming the Chemical Terrorism requires to improve the contents of two categories: Counter Citizen Response part and Initial Scene Response part. For Counter citizen response part' s sake, the web-sites of Response leader agencies for searching information about chemical terrorism should be modified specifically. These web-sites have to be re-organized in detail. The existing Information service system which has been vaguely informed as "CBRNE Accident" needs to be divided as "CBRNE Accident" and "WMD terrorism." Further, each of them should be specialized in "Chemical', "Biological", and "Radiological" categories. There is a need to rearrange current Emergency Instruction for civilians against chemical terrorism in feasible way. At the same time, it should be applied consistently to all organizations through agreement between experts and related-organizations. For Initial Scene Response part's sake, "Initial scene response procedure (SOP)" and "Operational conception" should be produced through Simulated Exercises and workshops of all organizations related with initial response. These organizations have to cooperate with Ministry of Environment which is the main leader Agency as the center. Next, there is a need to develop a technology and Scene Response Equipments, and to standardize the response equipments which consider the capability of First Responders for chemical terrorism. Especially, improving capability of equipments is required to overcome the vulnerability of Scene Response Equipments.

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320-Channel Multi-Frequency Trans-Admittance Scanner(TAS) for Anomaly Detection (도전율 및 유전율이 다른 병소의 검출을 위한 320-채널 다주파수 Trans-Admittance Scanner(TAS))

  • Oh, Tong-In;Lee, Min-Hyoung;Kim, Hee-Jin;Woo, Eung-Je
    • Journal of Biomedical Engineering Research
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    • v.28 no.1
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    • pp.84-94
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    • 2007
  • In order to collect information on local distribution of conductivity and permittivity underneath a scan probe, we developed a multi-frequency trans-admittance scanner (TAS). Applying a sinusoidal voltage with variable frequency on a chosen distal part of a human body, we measure exit currents from 320 grounded electrodes placed on a chosen surface of the subject. The electrodes are packaged inside a small and light scan probe. The system includes one voltage source and 17 digital ammeters. Front-end of each ammeter is a current-to-voltage converter with virtual grounding of a chosen electrode. The rest of the ammeter is a voltmeter performing digital phase-sensitive demodulation. Using resistor loads, we calibrate the system including the scan probe to compensate frequency-dependent variability of current measurements and also inter-channel variability among multiple. We found that SNR of each ammeter is about 85dB and the minimal measurable current is 5nA. Using saline phantoms with objects made from TX-151, we verified the performance of the lesion estimation algorithm. The error rate of the depth estimation was about 19.7%. For the size estimate, the error rate was about 15.3%. The results suggest improvement in lesion estimation algorithm based on multi-frequency trans-admittance data.

Object-Oriented Stereotactic Radiosurgery Planning System (객체 지향 개념을 이용한 뇌정위 방사선 수술 계획 시스템)

  • Park, S.H.;Suh, T.S.;Suh, D.Y.;Kang, W.S.;Ha, S.H.;Kim, I.H.;Park, C.I.
    • Proceedings of the KOSOMBE Conference
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    • v.1994 no.12
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    • pp.85-87
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    • 1994
  • In this paper, we present an object-oriented stereotactic radiosurgery planning system, which accepts medical images such as CT and angiography, transforms the coordinates to a reference frame coordinate, calculates dose distributions, and finally displays isodose curves over the images. The user finds an adequate one for radiosurgeries after performing computer simulations on different treatment parameter sets. The object-oriented design concept was fully applied to the system composed of seven manager objects of different classes: a patient information manager, a user-interface manager, a coordinate transformation manager, a blackboard manager, a dose calculation manager, an isodose curve display manager, and a report manager. All the user interactions are carried out through the use of mouse buttons. The performance of the system was verified by four physicians and two medical physicists, and now is being used in two clinical sites.

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Fast, Flexible Text Search Using Genomic Short-Read Mapping Model

  • Kim, Sung-Hwan;Cho, Hwan-Gue
    • ETRI Journal
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    • v.38 no.3
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    • pp.518-528
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    • 2016
  • The searching of an extensive document database for documents that are locally similar to a given query document, and the subsequent detection of similar regions between such documents, is considered as an essential task in the fields of information retrieval and data management. In this paper, we present a framework for such a task. The proposed framework employs the method of short-read mapping, which is used in bioinformatics to reveal similarities between genomic sequences. In this paper, documents are considered biological objects; consequently, edit operations between locally similar documents are viewed as an evolutionary process. Accordingly, we are able to apply the method of evolution tracing in the detection of similar regions between documents. In addition, we propose heuristic methods to address issues associated with the different stages of the proposed framework, for example, a frequency-based fragment ordering method and a locality-aware interval aggregation method. Extensive experiments covering various scenarios related to the search of an extensive document database for documents that are locally similar to a given query document are considered, and the results indicate that the proposed framework outperforms existing methods.

Microwave Radiation Effects on the Process of Escherichia coli Cultivation

  • Kuznetsov, Denis;Volkhin, Igor;Orlova, Ekaterina;Neschislyaev, Valery;Balandina, Alevtina;Shirokikh, Anna
    • Microbiology and Biotechnology Letters
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    • v.47 no.3
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    • pp.372-380
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    • 2019
  • Modern biotechnological industries have been attempting to improve the efficiency of bacterial strain cultivation. Millimeter wave electromagnetic radiation can have a varied influence on E. coli cultivation processes. The results of the study revealed that when a microwave radiation of low intensity is applied to positively adjust the conditions for the accumulation of bacterial culture biomass, a significant role is played not only by radiation parameters, but also by concomitant biological factors, which influence the reproducibility of the cultivation process and help obtain a useful biotechnological effect. The authors suggest a model that can be used to study the molecular mechanisms underlying the changes in the buildup of E. coli biomass under the influence of electromagnetic radiation.

Real-Time Moving Object Tracking System using Advanced Block Based Image Processing (개선된 블록기반 영상처리기법에 의한 실시간 이동물체 추적시스템)

  • Kim, Dohwan;Cheoi, Kyung-Joo;Lee, Yillbyung
    • Korean Journal of Cognitive Science
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    • v.16 no.4
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    • pp.333-349
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    • 2005
  • In this paper, we propose a real tine moving object tracking system based on block-based image processing technique and human visual processing. The system has two nun features. First, to take advantage of the merit of the biological mechanism of human retina, the system has two cameras, a CCD(Charge-Coupled Device) camera equipped with wide angle lens for more wide scope vision and a Pan-Tilt-Zoon tamers. Second, the system divides the input image into a numbers of blocks and processes coarsely to reduce the rate of tracking error and the processing time. Tn an experiment, the system showed satisfactory performances coping with almost every noisy image, detecting moving objects very int and controlling the Pan-Tilt-Zoom camera precisely.

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Study on Perception of High School Students of Biotechnology (생명공학 기술에 대한 고등학교 학생들의 인식 조사 연구)

  • Song, Shin-Cheol;Shim, Kew-Cheol
    • Hwankyungkyoyuk
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    • v.23 no.1
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    • pp.99-111
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    • 2010
  • The purpose of this study was to investigate high school students' perceptions of biotechnology. Participants in this study were 9th and 10th grade students who were enrolled in high schools in Gyeonggi Province. The survey instrument used in this study was a 26-item questionnaire that was designed to measure students' perceptions regarding biotechnology. The study revealed that students' perceptions were positive toward the use of biotechnology on biological objects such as plant, grain and microbes. However, their perceptions were negative toward the use of biotechnology on humans and animals. Male students' perceptions were more positive than female students and there were significant differences between male and female students(p<.01). The study also revealed that male and female students had positive perceptions about the use of biotechnology in the development of beneficial products. However, male students' perceptions were more positive than female students(p<.01). Female students' perceptions were slightly more negative than males and they indicated a measure of caution in the development of beneficial products using biotechnology. Regarding the reliability of biotechnological information acquired from food companies, TV broadcasters, and entertainers, male and female students tended to be highly negative. Students perceived that environmental, religious and ethical issues did not affect the use of biotechnology when asked the effect of these factors on the use of biotechnology. They perceived that food safety and genetic factors of microbes did affect the use of biotechnology. Thus, the study findings suggest that teaching and learning strategies based on the differences of perceptions between male and female students of this study be established and the use of media, development of teaching method and materials be promoted in order to enhance student's performance in environmental education.

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Automatic Liver Segmentation of a Contrast Enhanced CT Image Using a Partial Histogram Threshold Algorithm (부분 히스토그램 문턱치 알고리즘을 사용한 조영증강 CT영상의 자동 간 분할)

  • Kyung-Sik Seo;Seung-Jin Park;Jong An Park
    • Journal of Biomedical Engineering Research
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    • v.25 no.3
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    • pp.189-194
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    • 2004
  • Pixel values of contrast enhanced computed tomography (CE-CT) images are randomly changed. Also, the middle liver part has a problem to segregate the liver structure because of similar gray-level values of a pancreas in the abdomen. In this paper, an automatic liver segmentation method using a partial histogram threshold (PHT) algorithm is proposed for overcoming randomness of CE-CT images and removing the pancreas. After histogram transformation, adaptive multi-modal threshold is used to find the range of gray-level values of the liver structure. Also, the PHT algorithm is performed for removing the pancreas. Then, morphological filtering is processed for removing of unnecessary objects and smoothing of the boundary. Four CE-CT slices of eight patients were selected to evaluate the proposed method. As the average of normalized average area of the automatic segmented method II (ASM II) using the PHT and manual segmented method (MSM) are 0.1671 and 0.1711, these two method shows very small differences. Also, the average area error rate between the ASM II and MSM is 6.8339 %. From the results of experiments, the proposed method has similar performance as the MSM by medical Doctor.