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Microwave Radiation Effects on the Process of Escherichia coli Cultivation

  • Kuznetsov, Denis (Department of Manufacturing Technology for Drugs with a Course in Biotechnology, Perm State Pharmaceutical Academy) ;
  • Volkhin, Igor (Department of Electronic Engineering and Information Security, Perm State University) ;
  • Orlova, Ekaterina (Department of Manufacturing Technology for Drugs with a Course in Biotechnology, Perm State Pharmaceutical Academy) ;
  • Neschislyaev, Valery (Department of Manufacturing Technology for Drugs with a Course in Biotechnology, Perm State Pharmaceutical Academy) ;
  • Balandina, Alevtina (Department of Manufacturing Technology for Drugs with a Course in Biotechnology, Perm State Pharmaceutical Academy) ;
  • Shirokikh, Anna (Department of Manufacturing Technology for Drugs with a Course in Biotechnology, Perm State Pharmaceutical Academy)
  • Received : 2018.10.31
  • Accepted : 2019.02.18
  • Published : 2019.09.28

Abstract

Modern biotechnological industries have been attempting to improve the efficiency of bacterial strain cultivation. Millimeter wave electromagnetic radiation can have a varied influence on E. coli cultivation processes. The results of the study revealed that when a microwave radiation of low intensity is applied to positively adjust the conditions for the accumulation of bacterial culture biomass, a significant role is played not only by radiation parameters, but also by concomitant biological factors, which influence the reproducibility of the cultivation process and help obtain a useful biotechnological effect. The authors suggest a model that can be used to study the molecular mechanisms underlying the changes in the buildup of E. coli biomass under the influence of electromagnetic radiation.

Keywords

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