• Title/Summary/Keyword: biological behavior

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Debye Screening Effect on Scaling Behavior of Longest Relaxation Time of Biological Polyelectrolyte Chain

  • Lee, Jeong Yong;Sung, Jung Mun;Yoon, Kyu;Chun, Myung-Suk;Jung, Hyun Wook
    • Bulletin of the Korean Chemical Society
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    • v.34 no.12
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    • pp.3703-3708
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    • 2013
  • The scaling relationship of the longest relaxation time of a single chain of semiflexible biological polyelectrolyte has been investigated by performing well-established coarse-grained Brownian dynamics simulations. Two kinds of longest relaxation times were estimated from time-sequences of chain trajectories, and their behaviors were interpreted by applying the scaling law for different molecular weights of polyelectrolyte and Debye lengths. The scaling exponents for longest stress relaxation and rotational relaxation are found in the ranges of 1.67-1.79 and 1.65-1.81, respectively, depending on the physicochemical interaction of electrostatic Debye screening. The scaling exponent increases with decreasing screening effect, which is a special feature of polyelectrolytes differing from neutral polymers. It revealed that the weak screening allows a polyelectrolyte chain to follow the behavior in good solvent due to the strong electrostatic repulsion between beads.

Action Selections for an Autonomous Mobile Robot by Artificial Immune Network (인공면역망에 의한 자율이동로봇의 행동 선택)

  • 한상현;윤중선
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.532-532
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    • 2000
  • Conventional artificial intelligence systems are not properly responding under dynamically changing environments. To overcome this problem, reactive planning systems implementing new Al principles, called behavior-based Al or emergent computation, have been proposed and confirmed their usefulness. As another alternative, biological information processing systems may provide many feasible ideas to these problems. Immune system, among these systems, plays important roles to maintain its own system against dynamically changing environments. Therefore, immune system would provide a new paradigm suitable for dynamic problem dealing with unknown environments. In this paper, a new approach to behavior-based Al by paying attention to biological immune system is investigated. The feasibility of this method is confirmed by applying to behavior control of an autonomous mobile robot in cluttered environment.

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The Effect of Phenoxymethyl Side Groups on the Liquid Crystal Alignment Behavior of Polystyrene Derivatives

  • Kang, Hyo;Lee, Jong-Chan;Kang, Dae-Seung
    • Macromolecular Research
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    • v.17 no.7
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    • pp.506-515
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    • 2009
  • We synthesized a series of polystyrene derivatives containing various side chain terminal moieties, such as phenoxymethyl, 4-methoxyphenoxymethyl, 4-fluorophenoxymethyl, 4-methylphenoxymethyl, and 4-trifluoromethoxyphenoxymethyl groups, using polymer analogous reactions, in order to investigate the effect of the side group on their liquid crystal (LC) alignment behaviors. The polymers containing 4-fluorophenoxymethyl, 4-methylphenoxymethyl, or 4-trifluoromethoxyphenoxymethyl side groups had lower surface energy values and the LC cells fabricated using the unrubbed films of these polymers showed homeotropic LC alignment behavior. The LC cells fabricated using the rubbed films of the polymers containing phenoxymethyl or 4-fluorophenoxymethyl groups showed homogeneous planar LC alignment behavior in which the LCs were aligned perpendicular to the rubbing direction. This homogeneous planar and perpendicular alignment behavior was ascribed to the favorable anisotropic interactions between the LC molecules and the side groups preferentially oriented perpendicular to the rubbing direction.

Recent advances in intravital microscopy for investigation of dynamic cellular behavior in vivo

  • Choo, Yeon Woong;Jeong, Juhee;Jung, Keehoon
    • BMB Reports
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    • v.53 no.7
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    • pp.357-366
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    • 2020
  • Currently, most biological research relies on conventional experimental techniques that allow only static analyses at certain time points in vitro or ex vivo. However, if one could visualize cellular dynamics in living organisms, that would provide a unique opportunity to study key biological phenomena in vivo. Intravital microscopy (IVM) encompasses diverse optical systems for direct viewing of objects, including biological structures and individual cells in live animals. With the current development of devices and techniques, IVM addresses important questions in various fields of biological and biomedical sciences. In this mini-review, we provide a general introduction to IVM and examples of recent applications in the field of immunology, oncology, and vascular biology. We also introduce an advanced type of IVM, dubbed real-time IVM, equipped with video-rate resonant scanning. Since the realt-ime IVM can render cellular dynamics with high temporal resolution in vivo, it allows visualization and analysis of rapid biological processes.

Anatomical and Functional Comparison of the Caudate Tail in Primates and the Tail of the Striatum in Rodents: Implications for Sensory Information Processing and Habitual Behavior

  • Keonwoo Lee;Shin-young An;Jun Park;Seoyeon Lee;Hyoung F. Kim
    • Molecules and Cells
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    • v.46 no.8
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    • pp.461-469
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    • 2023
  • The tail of the striatum (TS) is located at the caudal end in the striatum. Recent studies have advanced our knowledge of the anatomy and function of the TS but also raised questions about the differences between rodent and primate TS. In this review, we compare the anatomy and function of the TS in rodent and primate brains. The primate TS is expanded more caudally during brain development in comparison with the rodent TS. Additionally, five sensory inputs from the cortex and thalamus converge in the rodent TS, but this convergence is not observed in the primate TS. The primate TS, including the caudate tail and putamen tail, primarily receives inputs from the visual areas, implying a specialized function in processing visual inputs for action generation. This anatomical difference leads to further discussion of cellular circuit models to comprehend how the primate brain processes a wider range of complex visual stimuli to produce habitual behavior as compared with the rodent brain. Examining these differences and considering possible neural models may provide better understanding of the anatomy and function of the primate TS.

Influence of Health Empowerment, Spousal Support, and Post-traumatic Growth on Health Behavior in Patients with Coronary Artery Disease (관상동맥질환자의 건강 임파워먼트, 배우자지지, 외상 후 성장이 건강증진행위에 미치는 영향)

  • Jeong, Eun;Lee, Kyung Sim;Yang, Seung Kyoung;Cho, Jang Hyun
    • Journal of Korean Biological Nursing Science
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    • v.24 no.2
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    • pp.113-121
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    • 2022
  • Purpose: The purpose of this study was to identify influence of health behavior in patients with coronary artery disease. Methods: A cross-sectional descriptive design included 150 patients treated with percutaneous coronary intervention in S hospital in S city. Data were collected by using self-questionnaires July 5-August 26, 2021 and were analyzed by descriptive statistics, t-test, ANOVA, Scheffé test, Pearson's correlation coefficients, and multiple regression with SPSS 23.0. Results: Factors significantly influencing health behavior in patients with coronary artery disease were health empowerment (β = .48, p< .001), and post-traumatic growth (β = .20, p= .013). The explanatory power of related variables was 39%. Conclusion: Based on the this study, it was found that health empowerment and post-traumatic growth had a significant effect on the health behavior of patients with coronary artery disease. Thus, it is necessary to promote the health behavior of patients with coronary artery disease through the development of intervention programs to improve health empowerment and post-traumatic growth.

Assertive Behavior in Asking Smokers Not to Smoke among Patients with Vascular Diseases (혈관질환자의 간접흡연 노출 시 흡연중단에 대한 주장행위 관련 요인)

  • Kim, Eun Kyung;Chae, Young Ran;Jung, Yun Hee;Park, Eun Ha
    • Journal of Korean Biological Nursing Science
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    • v.18 no.1
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    • pp.27-35
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    • 2016
  • Purpose: The purpose of this study was to identify the assertive behavior of asking smokers not to smoke and investigate the factors related to assertive behavior in patients with vascular diseases. Methods: Participants were 203 adult Korean patients with vascular diseases such as cerebral infarction and myocardial infarction. Data were collected using questionnaires that included the characteristics of secondhand smoke (SHS), secondhand smoke-related variables (Health belief model factors, health promotion model factors) and level of assertive behavior. Descriptive statistics, t-test, ANOVA and multiple regression using SPSS/WIN 18.0 were performed. Results: Participants who never ask smokers not to smoke was 39.9%, whereas participants who always ask was 7.4%. There was a weak positive relationship between assertive behavior and susceptibility to disease (r=.18), severity of disease (r=.19), benefit of assertive behavior to SHS exposure (r=.10), barrier of assertive behavior to SHS exposure (r=.24), and self-rated health (r=.21) respectively. There was a moderate positive relationship between assertive behavior and self-efficacy of assertive behavior to SHS exposure (r=.49). Health belief model factors explained 15.7% variance and health promotion model factors explained 27.0% of assertive behavior. Conclusion: The findings of this study suggest that self-efficacy of assertive behavior to SHS exposure is a very important factor. Therefore the development of a program to foster self-efficacy of assertive behavior regarding SHS exposure in patients with vascular diseases is needed.

Neural Circuit and Mechanism of Fear Conditioning (공포 조건화 학습의 신경회로와 기전)

  • Choi, Kwang-Yeon
    • Korean Journal of Biological Psychiatry
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    • v.18 no.2
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    • pp.80-89
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    • 2011
  • Pavlovian fear conditioning has been extensively studied for the understanding of neurobiological basis of memory and emotion. Pavlovian fear conditioning is an associative memory which forms when conditioned stimulus (CS) is paired with unconditioned stimulus (US) once or repeatedly. This behavioral model is also important for the understanding of anxiety disorders such as posttraumatic stress disorder. Here we describe the neural circuitry involved in fear conditioning and the molecular mechanisms underlying fear memory formation. During consolidation some memories fade out but other memories become stable and concrete. Emotion plays an important role in determining which memories will survive. Memory becomes unstable and editable again immediately after retrieval. It opens the possibility for us of modulating the established fear memory. It provides us with very efficient tools to improve the efficacy of cognitive-behavior therapy and other exposure-based therapy treating anxiety disorders.