• 제목/요약/키워드: biological age

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자궁내 인공수정 시술을 받은 원인불명 난임진단 여성의 임신성공 영향 요인: 배란유도 유형을 중심으로 (Factors affecting the Pregnancy Rate of Intra-Uterine Inseminations in Unexplained Infertile Couples in Korea: Focusing on Treatment Type for Inducing Ovulation)

  • 장인순;황나미;박승미
    • Journal of Korean Biological Nursing Science
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    • 제17권2호
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    • pp.211-217
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    • 2015
  • Purpose: The purpose of this study is to identify factors influencing the pregnancy rate among unexplained infertile couples who received treatments of assisted reproductive technology (ART) and intra-uterine inseminations (IUI). Methods: The medical records of 24,201 cases of unexplained infertility among a total of 31,684 intrauterine insemination treatment cases, (which benefited by 'National Medical-aid Program for ART in 2011') were used for this analysis. Results: Woman's age (OR=0.94), frequency of IUI (OR=0.86), and treatment type (OR=1.54) were significant factors on pregnancy rates in the logistic regression analysis. Conclusion: Factors, such as the age of the infertile woman, frequency of IUI, and treatment type used to induce ovulation were shown to positively influence pregnancy rate. However, the age of the spouse was not a significant variable. Infertile couples having unprotected sexual intercourse with unexplained infertility had priority. The results demonstrated that about 70% of infertile Korean couples had unexplained infertility. This was a higher rate of unexplained infertility than that of the clinical standard. Therefore, we should assess for causes through future studies. In addition, affective or emotional factors influencing unexplained infertility need to be researched further.

도시숲을 활용한 생활밀착형 산림치유 프로그램이 40대 이상 성인의 신체조성, 심리상태 및 삶의 질에 미치는 효과 (Effect of Life-Oriented Forest Healing Program in Urban Forest on Body Composition, Psychological State and Quality of Life of Adults over 40 Years of Age)

  • 강효영;임희경;채영란
    • Journal of Korean Biological Nursing Science
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    • 제24권1호
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    • pp.36-45
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    • 2022
  • Purpose: The purpose of this study was to verify physical and psychological effects of life-oriented forest healing program (LOFH) using urban forests in adults over 40 years of age. Methods: A non-equivalent control group pre-posttest design was used. There were 50 participants in the experimental group and 52 in the control group (a total of 102 individuals). The LOFH was conducted twice a week (3 hours per week) for a total of four weeks. Body composition, psychological states (such as depression and anxiety), and quality of life (QOL) were measured before and after the program. Results: Depression was significantly reduced in the group to which the forest healing program was applied. There was no significant difference in body composition (body mass index, body fat percentage, muscle mass, lean mass), other psychological states (anxiety, mood), or QOL. Conclusion: The LOFH was useful for improving depression in adults over 40 years of age. It is necessary to develop other LOFHs to improve body composition and quality of life.

한국 성인의 당뇨병 미진단 비율 영향요인: 2차 자료 분석 연구 (Factors related to undiagnosed diabetes in Korean adults: a secondary data analysis)

  • 김보현
    • Journal of Korean Biological Nursing Science
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    • 제25권4호
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    • pp.295-305
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    • 2023
  • Purpose: This study compared health behaviors and health-related clinical characteristics between individuals with normal glucose levels without diabetes and those with undiagnosed diabetes. Factors that were associated with undiagnosed diabetes were identified by sex. Methods: This was an observational study with a cross-sectional design based on data from the eighth Korea National Health and Nutrition Examination Survey, which used a stratified, multi-stage, cluster-sampling design to obtain a nationally representative sample. Multiple logistic regression analysis was employed to compute the odds ratios of health behaviors and clinical characteristics to identify risk factors for undiagnosed diabetes. Results: The overall prevalence of undiagnosed diabetes was 5.2% (weighted %, n = 700, p < .001). Among individuals with undiagnosed diabetes, 58.3% were men. Univariate logistic regression for undiagnosed diabetes identified sex, age, house income, educational level, and triglycerides as influencing factors. In multiple logistic regression by sex, the factors associated with undiagnosed diabetes in men were age, perceived health status, a diagnosis of angina, and triglycerides. Conclusion: Strategies should be targeted to improve health behaviors and clinical characteristics for specific age groups, men in bad perceived health status, women with high systolic blood pressure, and high triglycerides. Moreover, healthcare providers should understand the barriers to health behaviors and health-related quality of life to effectively deliver healthcare services.

시판 치과용 Au-Ag-Cu-Pd 합금의 등온시효경화거동 (Isothermal Age-hardening Behavior in the Commercial Dental Au-Ag-Cu-Pd Alloy)

  • 김형일;장명익;이유식
    • 대한의용생체공학회:의공학회지
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    • 제17권2호
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    • pp.247-254
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    • 1996
  • The relationship between the isothermal age-hardening behavior and the phase transformation in the commercial dental Au-Ag-Cu-Pd alloy was investigated Age-hardening was mostly attributed to the lattice distortions of the supersaturated w phase resulting from the transformation to the metastable phasel which were more distinct at lower aging temperature. The lattice distortions resulting from the transformation of the metastable phases to the equilibrium phases also made a contribution to the age-hardening.

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ON A CERTAIN FINITE DIFFERENCE SCHEME FOR A MODEL FOR DIFFUSION OF BIOLOGICAL POPULATIONS

  • Asghar, Kerayechian
    • Journal of applied mathematics & informatics
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    • 제6권2호
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    • pp.455-466
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    • 1999
  • In this note we present a numerical scheme for finding an approxximate solution of an equation which can be viewed as a model for spatial diffusion of age-depednent biological populations. Discretization of the model yields a linear system with a block tridi-agonal matrix. Our main concern will be discussion of stability for this scheme by examining the eigenvalues of the block tridiagonal matrix. Numerical results are presented.

방사선 직업 종사자의 자매염색분체교환 (Sister chromatid exchange in peripheral lymphocytes of radiation exposed workers in a hospital)

  • 홍해숙;나연경;하선옥;이정란
    • Journal of Korean Biological Nursing Science
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    • 제2권2호
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    • pp.90-101
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    • 2000
  • This study is being carried out, in two different random sample groups, between 20 men who were radiation exposed workers in the two general hospitals located in "T" city as a experimental group and 20 healthy men who were non-radiation exposed workers as a control group. The occurring frequency of the sister chromatid exchange as a biological dosemeter of radiation were studied. And the age, duration of employment and smoking were used as variable for the experiment. The results are as follows : The frequency of SCE were noticed respectively by each variable : 1) by age as a variable, the frequency were increased notably in radiation exposed workers group rather than a control group(p<0.05). 2) by duration of employment, the difference of the frequency were not recognised significantly in statistical among radiation exposed workers. 3) in smoker the frequency were increased notably in a radiation exposed workers than a control groups(p<0.05). Taking into consideration the above results, the age and smoking could affect the frequency of SCE, however, the size of sample were too small to generalize. Therefore, the following suggestions are recommended to get more accurate result. 1) In order to clarify the correlation in a smoking as variable, finding the volume of smoking and its related factor are necessarily required. 2) In order to confirm the correlation in each variable, adopting of a bigger-sized sample are needed and the study itself also be carried out repeatedly.

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한국 성인의 고 위험 당뇨에 대한 스트레스와 체질량 지수의 성별 차이 (Sex Difference in the Effect of Body Mass Index and Stress on High-Risk Diabetes Mellitus in Korean Adults)

  • 이혜순
    • Journal of Korean Biological Nursing Science
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    • 제21권3호
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    • pp.224-230
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    • 2019
  • Purpose: This study aimed to investigate sex differences in the effect of body mass index (BMI) and stress on high-risk diabetes mellitus (DM). Methods: Secondary analysis of data from 4,271 male and female adults participating in the Sixth Korea National Health and Nutrition Examination Survey 2015 was performed. The participants were evaluated using questionnaires and blood tests. Data were analyzed using descriptive statistics, t-test, ${\chi}^2-test$, and multiple logistic regression analysis (SPSS 24.0). Results: To identify sexspecific effects, interaction variables were included. Hemoglobin A1c (HbA1c) level was higher in men than in women, and the risk of DM decreased 0.31 times in women compared to that in men. As age increased, the odds of risk DM increased 1.03. The risk of DM increased 1.99 times in overweight individuals and 2.79 times for obese individuals compared to that in individuals with normal weight. Stress levels were higher in women than in men, but stress is not an influential factor in high-risk DM. In age-sex interaction, the odds of risk DM increased 1.02 in women compared to that in men as age increased. Conclusion: HbA1c level was affected by age-sex interaction, and age and sex should be considered in the application of HbA1c in the diagnosis of DM.

노화관련 질환에 대한 후성유전의 역할 (The Roles of Epigenetic Reprogramming in Age-related Diseases)

  • 황선화;김경민;김혜경;박민희
    • 생명과학회지
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    • 제33권9호
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    • pp.736-745
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    • 2023
  • 노화란 세포 및 생리 기능이 점진적으로 손상되는 복잡한 과정이다. 알츠하이머, 동맥경화 및 갱년기와 같은 노화와 관련된 질병은 노화가 진행이 되면서 발생된다. 노화와 관련된 질환은 다양한 원인에 의해 발생된다. 그 중 유전적인 변화 없이 유전자 발현을 조절하는 후성유전의 변화는 노화, 그리고 노화와 관련된 질환의 발생에 중요한 조절자로 알려져있다. 이 리뷰에서는 후성유전의 변화가 노화 및 노화와 관련된 질병의 발전과 진행에 어떠한 역할을 하는지에 대해 서술하였다. 노화 중에 일어나는 유전적 변화의 분자적 기전과 이러한 변화가 노화와 관련된 질병에 미치는 영향, 특히 노화와 관련된 질환과 관련된 유전자 발현 양식을 조절하는 RNA 메틸화, DNA 메틸화 및 miRNA에 대해 중점적으로 초점을 맞추었다.