• Title/Summary/Keyword: biochemical indicators

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The Effect of Sports Drink Containing Schizandra Chinensis on Blood Biochemical Elements, Exercise Performance and HSP70 (오미자를 이용한 스포츠 드링크 섭취가 혈액성분과 운동수행력 및 HSP70에 미치는 영향)

  • 오재근;김복주;신영오;정희정
    • The Journal of Korean Medicine
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    • v.23 no.2
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    • pp.139-150
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    • 2002
  • OBJECTIVES : Schizandra chinensis is well known for its efficacy at liver function reinforcement, relieving thirst and recovery from fatigue. In this study, we examined the effects of sports drink containing Schizandra chinensis on serum metabolic substrate, electrolyte, stress indicators, related-enzyme and exercise performance, rectal temperature, and heat shock proteinb70 (HSP70). METHODS : Elite long-distance runners (male, 21.3yrs, n=16) were selected and divided into two groups; an experimental group (EXP, n=8) and a control group (CON, n=8). A beverage containing Schizandra chinensis was supplemented 3 times per day to EXP for 4 weeks. Serum biochemical elements (glucose, lactate, total cholesterol, triglyceride, high density lipoprotein cholesterol, glutamate oxaloacetate transaminase, glutamate pyruvate transaminase, creatinine, creatine phosphokinase, lactate dehydrogenase, blood urea nitrogen, Na, K, Cl) were analyzed by auto blood analyzer. Exercise performance was measured by treadmill exercise test, HSP70 was detected by electrophoresis and Western blotting, and rectal temperature was measured by rectal temperature probe. RESULTS : Administration of the beverage increased significantly the rest level of blood Na, Cl and glucose and decreased significantly lactate dehydrogenase, glutamate oxaloacetate transaminase. No difference was found in exercise performance, rectal temperature increment or HSP70 concentration between groups. CONCLUSIONS : Administration of a sports drink containing Schizandra chinensis altered blood glucose, lactate dehydrogenase, glutamate oxaloacetate transaminase, Na and Cl levels.

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Quality assessment and acceptability of whiteleg shrimp (Litopenaeus vannamei) using biochemical parameters

  • Kim, So-Hyun;Jung, Eun-Ju;Hong, Dong-Lee;Lee, Seung-Eun;Lee, Yang-Bong;Cho, Sueng-mok;Kim, Seon-Bong
    • Fisheries and Aquatic Sciences
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    • v.23 no.9
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    • pp.21.1-21.10
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    • 2020
  • Background: This study aimed to provide a basic standard for assessing freshness and acceptability of whiteleg shrimp (Litopenaeus vannamei). Methods: It was divided into whole body and meat and stored at 25 ℃ to evaluate both quality and freshness changes that occur over time. The shelf life of shrimp was estimated as 17 and 20 h for whole body and meat, respectively. Results: In chemical analysis, K-value increased from 9.96 to 12.32% to a maximum of 75.14%, and TVB-N increased from 1.86 mg/100 g to 34.71 mg/100 g. For volatile sulfur compounds, methyl mercaptan and dimethyl disulfide increased from 0.00 mg/100 g to 1.10 mg/100 g and 1.26 mg/100 g, respectively, rapidly increasing with decreasing freshness. Conclusion: Changes in all biochemical indicators significantly correlated with the sensory evaluation results. This study contributes to the knowledge about whiteleg shrimp spoilage and freshness, providing a basis for developing methods to improve shrimp quality control and management.

Physiological and Biochemical Responses of Fifteen Rice Cultivars to UV-B Radiation

  • Sung Jwa-Kyung;Chung Jong-Wook;Lee Sang-Min;Lee Yong-Hwan;Choi Du-Hoi;Kim Tae-Wan;Song Beom-Heon
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.50 no.1
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    • pp.39-44
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    • 2005
  • This study was conducted to examine the physiological and biochemical responses against UV-B radiation in the seedling of 15 different rice cultivars, having the different physiological sensitivities. Out of 15 rice cultivars tested, moderate and susceptible groups showed significant decreases in biomass and RGR (relative growth rate). Contents of total chlorophyll were reduced remarkedly by irradiation of UV-B. In all rice cultivars tested, the content of chlorophyll a was strongly decreased, while the contents of chlorophyll b were slightly reduced without showing clear different among three groups and 15 cultivars. Carotenoid content was largely reduced by UV-B radiation, whereas polyamine content was moderately increased. The contents of MDA (malondialdehyde) that reflect the level of lipid peroxidation of cell membranes were clearly increased by UV-B stress, showing higher content in susceptible cultivars than moderate and torelant cultivars. The physiological important parameters highly related to visible injury were leaf color, chlorophyll, carotenoid, and lipid peroxidation, whereas biomass and polyamines were not closely correlated. Based on this results, it was concluded that changes of visible injury and the contents of chlorophyll and MDA could be adequately applied and utilized as physiological indicators to UV-B radiation.

Novel two-stage hybrid paradigm combining data pre-processing approaches to predict biochemical oxygen demand concentration (생물화학적 산소요구량 농도예측을 위하여 데이터 전처리 접근법을 결합한 새로운 이단계 하이브리드 패러다임)

  • Kim, Sungwon;Seo, Youngmin;Zakhrouf, Mousaab;Malik, Anurag
    • Journal of Korea Water Resources Association
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    • v.54 no.spc1
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    • pp.1037-1051
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    • 2021
  • Biochemical oxygen demand (BOD) concentration, one of important water quality indicators, is treated as the measuring item for the ecological chapter in lakes and rivers. This investigation employed novel two-stage hybrid paradigm (i.e., wavelet-based gated recurrent unit, wavelet-based generalized regression neural networks, and wavelet-based random forests) to predict BOD concentration in the Dosan and Hwangji stations, South Korea. These models were assessed with the corresponding independent models (i.e., gated recurrent unit, generalized regression neural networks, and random forests). Diverse water quality and quantity indicators were implemented for developing independent and two-stage hybrid models based on several input combinations (i.e., Divisions 1-5). The addressed models were evaluated using three statistical indices including the root mean square error (RMSE), Nash-Sutcliffe efficiency (NSE), and correlation coefficient (CC). It can be found from results that the two-stage hybrid models cannot always enhance the predictive precision of independent models confidently. Results showed that the DWT-RF5 (RMSE = 0.108 mg/L) model provided more accurate prediction of BOD concentration compared to other optimal models in Dosan station, and the DWT-GRNN4 (RMSE = 0.132 mg/L) model was the best for predicting BOD concentration in Hwangji station, South Korea.

Interaction of lead and selenium on several aspects of thyroid, liver, and kidney function in guinea pigs (기니픽에서 갑상선, 간 및 신기능에 미치는 납과 selenium의 상호관계)

  • Kim, Jin-sang;Kang, Hyung-sub;Kang, Chang-won
    • Korean Journal of Veterinary Research
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    • v.36 no.3
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    • pp.699-707
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    • 1996
  • This study was designed to examine the involvement of lead in function of target organ, and the protective effect of selenium in lead-treated guinea pigs for 8 weeks. The effects of exposure to 0.5% lead acetate(lead) and/or 4ppm sodium selenite(selenium) in feed on serveral aspects were evaluated by measuring thyroid stimulating hormone(TSH), triiodothyronine($T_3$), thyroxine($T_4$), serum biochemical activities, organ weights, and serum and organ lead concentrations in growing animals. The many indicators of endocrine function(TSH, $T_3$, and $T_4$ in serum), enzyme and biochemical activities(${\alpha}$-glutamyltranspeptidase, alkaline phosphatase, lactate dehydrogenase, triglyceride, creatinine, $Ca^{2+}$ in serum), and organ weights(kidney, spleen and testis) were correlated with lead exposure or showed significantly different mean values between the exposed and controls. These changes on some aspects were reversed by combination-fed of selenium, but did not statistically significant. The organ(kidney, liver, spleen, testis and brain) and serum lead concentrations of lead-fed group were clearly higher than that of controls. Selenium supplementation resulted in a significant protection against lead accumulation in liver and testis. These results suggest that lead can cause a toxic effect on several organ and that selenium seems to has a protective effect on specific reaction by lead-induced organic function toxicity.

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Colour change functional dyes based on cross-conjugated donor-acceptor chromophores

  • Park, Soo-Youl;Oh, Sea-Wha;J. Griffiths
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2000.04a
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    • pp.150-151
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    • 2000
  • Some chromophores that can undergo a pronouncend colour change when acted upon an extenal agency, such as light, heat, pH, or chemical agents, have many potential applicationa as functional dyes. They may be used as indicators, optical sensors, biochemical probes, optical and thermal recording materials. The results will investigate donor-acceptor chromophores which have the potential for such colour change processes. In particular, cross-conjugated donor-acceptor chormophores, analogous to indigo and squarylium-type chromophores, will be examined for pH sensitizing and for their oxidation-reduction colour change behaviour.

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Relationships among Fasting Serum Insulin, Free Fatty Acid, Lipid Levels and Anthropometric Measurements in Female College Students (여대생의 혈청 인슐린, 유리지방산, 지질 농도와 신체계측치와의 관련성)

  • 김석영
    • Journal of Nutrition and Health
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    • v.32 no.2
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    • pp.189-196
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    • 1999
  • This study was conducted to investigate the relationships among the levels of fasting serum insulin, free fatty acid, lipids and anthropometry in normal-weight female college students. Serum insulin and free fatty acid levels were negatively correlated. However, insulin, triglyceride, and cholesterol levels were not correlated with fat mass or BMI(body mass index). The ability of anthropometric and biochemical indicators to predict fatness could be important for epidemiologic and clinical research. In the subjects, waist cirumference was correlated with BMI, fat mass and percent body fat, and HDLC/CHOL (high density lipoprotein cholesterol/cholesterol)was correlated with body weight, BMI, and fat mass. Our data suggests than waist circumference and HDLC/CHOL are predictors of fatness, whereas WHR apears to be a less important contributor to fatness in female college students.

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Indicators of Nutritional Status on the Basis of Preschool Children's Anthropomary (학경전 아동의 신체 발달과 영양 상태 지표에 관한 연구)

  • 문현경
    • Journal of Nutrition and Health
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    • v.31 no.8
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    • pp.1283-1294
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    • 1998
  • This study was conducted to investigate nutritional status by anthropometric meas-urement and to assess the validity of indicators for nutritional status of preschool children. Health examinations, including blood and urine tests, were done for 799 childern aged 2 to 6 years. The mean anthropometric measurements of height, weight , head circumference, and chest circumference were 90.2cm, 13.9kg, 47.7cm, 50.9cm for 2 years (n=13), 94.8cm, 15.2kg, 43.3cm, 47.0cm for 3 years(n=125), 100.7cm, 16.4kg, 46.2cm, 50.5cm for 4 years(n=272), 106.5cm, 18.1kg, 48.8cm, 53.8cm for 5 years(n=253), 113.0cm 20.4kg, 50.4cm 56.9cm for 6 years(n=136), respectively. All anthropometric measureemnts were significantly different by age and sex. The results of physical examinations excluding dental examination were normal for all studied children. Urine test results were also normal for the subjects. The most common blood type was A and the rarest one was type AB. The mean hemoglobin concentration was 11.84g/dl for boys(n=398), 11.86g/dl for girls, and 11.85kg/dl for all. The percentage of childeren whose hemoglobin concentration was less than 11.0g/dl was 21.6% for boys and 18.9% for girls. The percentage of children whose height for age, weight for age, and weight for height were in the rang of median $\pm$1 standard devication(S.D) was 71.7% , 65.6%, and 67.0% for each indicator. Obese childeren whose weight for height or weigth for age was more than median +2S.D. were 5.2% while tall children whose height for age was more than median +2S.D, were 1.8% . Past and recent nutritional status of most children(87.2%) were assessed as normal by the combination of three indicators(height for age, weight for age, weight for height). The percentate of coincidence between for height) and one assessed by anthropometric measurements (height for age, weight for age, weight for height) and one assessed by physicial was 59.6%, 69.3% and 67.8% for each indicator, respectively. The distribution of subjects by height for age was significantly different between normal and anemic groups. With these results , the nutritional status of children the studied was normal. The anthropometric measurements reflected the nutritional status of childeren relatively well. In conclusion, in comparison with biochemical meausurements anthropometric measurements are relatively simple and effective indicators for nutritional assessement of children in large health and nutrition suveys in Korea.

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Nutrition Assessment of Older Subjects in a Health Care Center by MNA (Mini Nutritional Assessment) (MNA (Mini Nutritional Assessment)를 이용한 건강증진센터 내원 노인의 영양상태 판정)

  • Lee, Hye-Ok;Lee, Jeong-Sook;Shin, Ji-Won;Lee, Geum-Ju
    • Journal of the Korean Dietetic Association
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    • v.16 no.2
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    • pp.122-132
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    • 2010
  • Elderly people comprise an increasing proportion of the population, and nutritional impairments may contribute to health problems among this group. This study was conducted to evaluate the nutritional status by Mini-Nutritional Assessment (MNA) and to identify relationships among anthropometric measurements, biochemical indicators, bone Mineral Density (BMD) and MNA results among older adults (${\geq}$65 yrs, n=98, 66.7${\pm}$2.5 yrs; M=52, F=46, BMI 24.5${\pm}$2.8 $kg/m^2$) at a Health Care Center. A dietitian administered MNA and collected anthropometric measurements (weight, height, waist circumference), biochemical indicators (albumin, hemoglobin, hematocrit, TLC, glucose, lipids) and the BMD (spine, femur, F=46). Subjects were grouped into a normal nutrition group (0~2 risk factors of malnutrition) and a high risk of malnutrition group (>=3 risk factors of malnutrition) based on their risk factor status for malnutrition. The risk factors for malnutrition include age ${\geq}$65 years, PIBW <90%, albumin <3.5 g/dl, TLC <1,500%, Hgb <14 g/dl (men), Hgb <10 g/dl (women), loss of appetite and weight loss 1~3 kg/last 3 months. In addition, subjects were grouped into a normal, osteopenia and osteoporosis group by BMD. We found that 12% of the subjects were at risk of malnutrition (MNA score, 21.4${\pm}$2.1) and that 88% were well nourished (27.3${\pm}$1.5) according to the MNA. Full-MNA scores were positively and significantly (p<0.05) associated with BMI, mid-arm circumference (MAC), calf circumference (CC), albumin and hemoglobin, respectively. The full-MNA score of the high risk of malnutrition group (23.0${\pm}$3.8) was lower than that of the normal nutrition group (27.0${\pm}$2.1) (p<0.05). In addition, the Full-MNA score was negatively associated with the risk factor of malnutrition (r=-0.35, p=0.0004). We found that 39.1% of the subjects had osteoporosis, 45.7% had osteopenia and 15.2% were normal according to their BMD. The MNA score of osteoporosis group (24.58${\pm}$3.3) was lower than that of the normal (27.4${\pm}$1.1) and osteopenia group (26.9${\pm}$1.5) (p<0.05). These results suggested that MNA can be useful as a nutritional screening tool of older adults in Health Care Centers.

Serum enzymes as indicators of radiation exposure in rat (흰쥐의 방사선 피폭후 생물학적 지표로서의 혈액효소)

  • Kim, In-Gyu;Kim, Sang-Bok;Kim, Jin-Gyu;Kim, Kug-Chan;Chun, Ki-Chung;Park, Hyo-Kook;Lee, Kang-Suk
    • Journal of Radiation Protection and Research
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    • v.18 no.2
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    • pp.37-45
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    • 1993
  • Enzyme activity changes in rat blood as biochemical indicator useful for evaluating exposure dose were experimentally studied. The experimental results obtained are as follows: 1) Alkaline phosphatase activities increased in the blood serum until 24 hours after 0.1, 0.25, 0.5, 2 and 4Gy irradiation and its activities returned normal condition after 72 hours of post-irradiation. Creatine kinase activities increased in the blood serum until 72 hours after 2 and 4Gy irradiation but any significant activity changes were not detected after 0.1, 0.25Gy irradiation. 2) Malate dehydrogenase activities did not reveal available changes after 0.1, 0.25, 0.5 Gy irradiation and lactate dehynrogenase activities decreased in the blood serum after 0.1, 0.25, 0.5 Gy irradiation.3) Glutamate oxaloacetate transaminase activity changes were detected in the blood serum after 0.1, 0.25, 0.5, 2, 4Gy(0.1Gy/min.) and GOT activities increased after 0.5, 1, 1.5, 2, 3, 5, 7Gy(0.5Gy/sec.). Any acid phosphatase activities were detected in the blood serum after 0.1, 0.25, 0.5, 2, 4Gy(0.1Gy/min.) and 0.5, 1, 1.5, 2, 3, 5, 7Gy(0.5 Gy/sec.) irradiation. Potentially some of these enzymes can be used as indicator protein for radiation injury. Futher investigation is needed to find better biochemical indicators utilizing recent know-ledge and techniques of biochemistry.

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