• Title/Summary/Keyword: bio-medical

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Physiological Activity of Coptis japonica, White Poria cocos, and Cimicifuga heracleifolia and a Mixture of Their Extracts on Skin Based on The Oriental Medicine OMiYakSung Theory (오미약성이론을 활용한 황련, 승마, 백복령 및 복합물의 생리활성)

  • Ryu, Hwa Sun;Oh, Seong-Hwa;Lee, Jung-No;Kim, Hee-Taek;Ha, Hun-Yong;Kim, Yong-Min;Park, Sung-Min
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.45 no.1
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    • pp.77-85
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    • 2019
  • OMiYakSung theory consists of various herbs that contain at least one or more of the five flavors. This theory has been used to prevent human diseases and enhance the immune system. The main objective of the present study was to investigate efficacy differences and changes in ingredients of blended and single herb extracts based on OMiYakSung theory. We selected three herbs Coptis japonica Makino, Cimicifuga heracleifolia Komarov, and white Poria cocos and assessed their physiological effect. As results, the blended extracts showed excellent cell migration effect at 400 ug/mL concentration, compared to the single extract. In addition, the blended extracts enhanced immune function by increasing the activity of dendritic cells and showed the highest antioxidant activity by DPPH assay and HPLC-ABTS assay. In this study, we developed a new materials that can be applicable to cosmetics and pharmaceuticals field by applying oriental medicine theory.

A study on efficacy and safety of Bio-Gammamix by oral administratiion to cultured fish (양식어류에 있어서 생약제제(바이오감마믹스)의 경구투여에 의한 효능 및 안전성에 관한 연구)

  • Heo, Gang-joon;Kim, Byeung-gie;Yeh, Jae-gill;kim, Jeong-ho
    • Korean Journal of Veterinary Research
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    • v.34 no.3
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    • pp.627-633
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    • 1994
  • A study on efficacy and safety of Bio-Gammamix was performed to use for the preventive drug against bacterial diseases to mirror carp(Cyprinus carpio), rainbow trout(Salmo gairdneri), eel(Anguilla japonica) and flounder(Paralichthys olivaceus). The main ingredients of Bio-Gammamix were ferrous fumarate and mixed extrated powders of licorice root, ox bile and garlic. The test drug was proved to improve feeding habit and feed efficiency and decrease cumulative mortality remarkably. After administration, no side effects and histopathological changes were observed. We can prevent outbreaks of bacterial diseases of fish by the dosage of 1kg/ton of fish body weight perorally once or two times in a day for 7 days and Bio-Gammamix is thought to be used effectively an widely against most bacterial fish pathogens.

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Bio-fusion and Medical Device Industry (바이오융합 및 의료기기 산업)

  • Park, Su A;Lee, Jun Hee;Kim, Wan Doo
    • Transactions of the KSME C: Technology and Education
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    • v.5 no.1
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    • pp.23-52
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    • 2017
  • Bio-fusion and medical device industry is the multidisciplinary engineering application technology industries, which are fused, such as electricity, electronics, machinery, materials. It aims to improve the quality of human life by using bio-fusion and medical devices, and is an important industry recognition and brand power for the product. However, there is a period that is required from the development of products with technology-dependent industries. Therefore, it is necessary to have continuous effort for industrial investment in research and development at the national level including technical support, institutional support, and human resources.

Bio-gas Production from Nemopilema nomurai Using Anaerobic Digestion (혐기성 소화를 이용한 노무라입깃 해파리로부터 바이오 가스 생산)

  • Kim, Ji-Youn;Lee, Sung-Mok;Kim, Jong-Hun;Lee, Jae-Hwa
    • KSBB Journal
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    • v.25 no.6
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    • pp.547-552
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    • 2010
  • The recent bloom of a very large jellyfish Nemopilema nomurai has caused a danger to sea fishery and sea bathers. Presently, Nemopilema nomurai is thrown away through a separator system in the sea. The objective of this work was to produce bio-gas from Nemopilema nomurai by using anaerobic digestion. The bio-gas includes the hydrogen or the methane gases. It relates that Nemopilema nomurai is effectually changed into the renewable energy. When the jellyfish biomass was used as an organic carbon source the bio-gases were evolved. The aim of this study was to determine the optimal conditions for hydrogen and methane gases production according to the substrate concentrations of Nemopilema nomurai, optimal culture condition and the sludge-pretreatment without pH control. The optimal culture condition was found to be $35^{\circ}C$ and the heat-treatments of jellyfish was done at $120^{\circ}C$ for 30 min. The production rate of hydrogen and methane gas were found to be 8.8 mL/L/h, 37.2 mL/L/h from 1.5 g of dry Nemopilema nomurai.

Application of a Diode Laser Colorimetric Spectrometer to Determination of Cetylpyridinium Chloride (다이오드 레이저 비색 분광기를 이용한 Cetylpyridinium Chloride의 농도분석)

  • Park, Keun-Woo;Kim, Se-Yun;Shin, Chul-Min;Seo, Jeong-Woon;Hyun, Hye-Jin;Nam, Hae-Seon;Kim, Sung-Ho
    • Proceedings of the KAIS Fall Conference
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    • 2003.06a
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    • pp.307-310
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    • 2003
  • In order to analyze the concentration of cetylpyridinium chloride(CPC), a widely used cationic surfactant, we developed a simple and compact spectrometer, which consisted of a diode laser and a photodiode detector. Preliminary results are described here on the performances of the system in terms if the stability of output intensity, sensitivity, and reproducibility. Data on the comparisons of the system with the conventional UV-VIS spectrometer are also given. With the instrument, the concentration of CPC between 3${\times}$10$\^$-5/M and 1.1${\times}$ 10$\^$-4/M are calibrated as a correlation coefficient of 0.9635. The results shown here indicate a potential for developing a portable spectrometer useful for analyzing concentrations of CPC.

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Growth Characteristics of Polyporales Mushrooms for the Mycelial Mat Formation

  • Bae, Bin;Kim, Minseek;Kim, Sinil;Ro, Hyeon-Su
    • Mycobiology
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    • v.49 no.3
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    • pp.280-284
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    • 2021
  • Mushroom strains of Polyporales from the genera Coriolus, Trametes, Pycnoporus, Ganoderma, and Formitella were explored in terms of mycelial growth characteristics for the application of mushroom mycelia as alternative sources of materials replacing fossil fuel-based materials. Among the 64 strains of Polyporales, G. lucidum LBS5496GL was selected as the best candidate because it showed fast mycelial growth with high mycelial strength in both the sawdust-based solid medium and the potato dextrose liquid plate medium. Some of the Polyporales in this study have shown good mycelial growth, however, they mostly formed mycelial mat of weak physical strength. The higher physical strength of mycelial mat by G. lucidum LBS5496GL was attributed to its thick hyphae with the diameter of 13 mm as revealed by scanning electron microscopic analysis whereas the hyphae of others exhibited less than 2 mm. Glycerol and skim milk supported the best mycelial growth of LBS5496GL as a carbon and a nitrogen source, respectively.

Maxillary sinus floor augmentation with anorganic bovine bone : Histologic evaluation in humans (Anorganic bovine bone을 이용한 상악동저 거상술의 조직학적 평가)

  • Son, Woo-Kyung;Shin, Seung-Yun;Yang, Seung-Min;Kye, Seung-Beom
    • Journal of Periodontal and Implant Science
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    • v.39 no.1
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    • pp.95-102
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    • 2009
  • Purpose: The aim of this report is to investigate the efficacy of anorganic bovine bone xenograft(Bio-$Oss^{(R)}$) at maxillary sinus floor augmentation. Materials and methods: Two male patients who missed maxillary posterior teeth were included. They were performed maxillary sinus floor augmentation using anorganic bovine bone xenograft(Bio-$Oss^{(R)}$). After 10 or 13 months, the regenerated tissues were harvested using trephine drills with 2 or 4mm diameter and non-decalcified specimens were made. The specimens were examined histologically and histomorphometrically to investigate graft resorption and new bone formation. Results: Newly formed bone was in contact with Bio-$Oss^{(R)}$ particles directly without any gap between the bone and the particles. The proportions of newly formed bone were $23.4{\sim}25.3%$ in patient 1(Pt.1) and 28.8% in patient 2(Pt.2). And the proportions of remained Bio-$Oss^{(R)}$ were $29.7{\sim}30.2%$ in Pt.1 and 29.2% in Pt.2. The fixtures installed at augmented area showed good stability and the augmented bone height was maintained well. Conclusion: Anorganic bovine bone xenograft(Bio-$Oss^{(R)}$) has high osteoconductivity and helps new bone formation, so that it can be used in maxillary sinus floor augmentation.

An Implementation of Waiting Queue System based on Mobile NFC (모바일 NFC기반의 순번대기 시스템의 설계)

  • Kim, Sang-yoon;Cho, Kyung-rae;Kim, Jung-han;Bae, Sung-ho;Kang, Sung-in
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.05a
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    • pp.862-865
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    • 2013
  • The smartphone digs deep into our lives, is changing our life. With increases the penetration of smart phones, it getting better performance. In recent years, tend to increase its utilization by an increase in the prevalence of smart phones equipped with NFC short-range wireless communication technology based on RFID in a number of areas, including e-cards, tagging. In this paper, we implement a system that can operate the system by traditional saddlecloth way of waiting waiting waiting standby system more efficient by applying NFC.

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Diversity and Chemical Defense Role of Culturable Non-Actinobacterial Bacteria Isolated from the South China Sea Gorgonians

  • Jiang, Peng;Zhang, Xiaoyong;Xu, Xinya;He, Fei;Qi, Shuhua
    • Journal of Microbiology and Biotechnology
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    • v.23 no.4
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    • pp.437-443
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    • 2013
  • The diversity of culturable non-actinobacterial (NA) bacteria associated with four species of South China Sea gorgonians was investigated using culture-dependent methods followed by analysis of the bacterial 16S rDNA sequence. A total of 76 bacterial isolates were recovered and identified, which belonged to 21 species of 7 genera, and Bacillus was the most diverse genus. Fifty-one percent of the 76 isolates displayed antibacterial activities, and most of them belonged to the Bacillus genus. From the culture broth of gorgonian-associated Bacillus methylotrophicus SCSGAB0092 isolated from gorgonian Melitodes squamata, 11 antimicrobial lipopeptides including seven surfactins and four iturins were obtained. These results imply that Bacillus strains associated with gorgonians play roles in coral defense mechanisms through producing antimicrobial substances. This study, for the first time, compares the diversity of culturable NA bacterial communities among four species of South China Sea gorgonians and investigates the secondary metabolites of gorgonian-associated B. methylotrophicus SCSGAB0092.