• Microbiology and Biotechnology Letters
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• v.42 no.4
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• pp.367-376
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• 2014

This study's purpose was to investigate the characteristics of a traditional Korean rice wine containing lactic acid bacteria (LAB), called makgeolli. The makgeolli was brewed with the alcohol-tolerant Pediococcus acidilactici strain K3, and was analyzed for LAB cell counts, alcoholic content, turbidity, pH, total acidity, amino nitrogen, total sugars, reducing sugars, solid contents, and organic acids. The physicochemical properties of the makgeolli were mostly maintained during fermentation (9 d) and storage (15 d). We also monitored the properties of LAB-supplemented commercial makgeollies, after adding P. acidilactici K3 at a concentration of $10^7CFU/ml$ makgeolli, for one month. Most of their properties, such as alcoholic content, turbidity, pH, total acidity, amino nitrogen, total sugars, reducing sugars, solid contents, and organic acids, were preserved during storage at $10^{\circ}C$, suggesting that makgeolli supplemented with live LAB can be produced. These results suggest that alcohol-tolerant P. acidilactici K3 can be used for makgeolli brewing either as a starter or as a supplement.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.14 no.2
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• pp.168-174
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• 2021

According to the World Agricultural Productivity Report, the current annual average growth rate of agriculture is 1.63%, which is lower than 1.73% to support the world's 10 billion people, which is growing by 2050. The demand for food, feed, and bioenergy is not growing enough to continue to meet the demand, and it is predicting a future food shortage. The purpose of this study was to create a regional irrigation control model for the purpose of reducing the production cost of crops, increasing production, and improving quality, and presenting a model that can give advice to farmers who start farming in the region. The irrigation control modeling presented in this study means to represent the change of medium weight·supply liquid·drainage amount due to changes in the root zone environment according to the passage of time and climate in a graph model. For water control modeling, we collected data on the change in the amount of the root zone environment and the weight of the badge·supply amount·drainage amount from March to June in Nonsan, Buyeo, and Yesan regions in Chungnam Province through the measuring device of the Ministry of Environment in the root region. We set up the parameters for derivation and derived an irrigation control model that can confirm the change in weight·supply liquid·drainage amount over time through the parameters.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.6
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• pp.764-771
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• 2018

Domestic and foreign agricultural environments nowadays are undergoing various changes such as aging of agricultural population, increase of earned population, rapid climate change, diversification of agricultural product distribution structure, depletion of water resources and limited cultivation area. In order to respond to various environmental changes in recent agriculture, practical use of Smart Greenhouse to easily record, store and manage crop production information such as crop growing information, growth environment and agriculture work log, Interest is growing. In this paper, we propose a system that collects the situation information necessary for growth such as temperature, humidity, solar radiation, CO2 concentration, and monitor the collected data, which can be measured in the rhizosphere of the crop. We have developed a system that collects data such as temperature, humidity, radiation, and growth environment data, which are measured by data obtained from the rhizosphere measuring section of a growing crop and measured by a sensor, and transmitted to a wireless communication gateway of 400 MHz. We developed the integrated SW that can monitor the rhythm environment data and visualize the data by using cloud based data. We can monitor by graph format and data format for visualization of data. The existing smart farm managed crops and facilities using only the data within the farm, and this study suggested the most efficient growth environment by collecting and analyzing the weather and growth environment of the farms nationwide.

• Microbiology and Biotechnology Letters
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• v.47 no.1
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• pp.164-171
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• 2019

Radiation therapy has many side effects, such as digestive mucosal ulcers, without regard to its efficacy. The purpose of this study is to address an alternative method to replace the limitation of radiation therapy using radiomimetic microbial ribotoxins. In the evaluation of cancer therapy, we analyzed the formation of colorectal cancer (CRC) cell spheroids, which can take into account the heterogeneous cellular constitution, tumor stem cells, and the surrounding microenvironment. Ribotoxic stress interfered with the spheroid structure composed of relatively small clusters. Spheroids under ribotoxic stress were structurally sparse and their shrinkage was very slow. In the control group, the clusters of strongly aggregated cells were resistant to physical stress, but the ribotoxic stress-exposed spheroids were easily broken up by the physical stress. Moreover, the ribosome-insulted CRC cells slowly migrated to form clusters and the cell-cell junctional points in the ribosome-insulted spheroids were rarer than those in the control CRC spheroid. Moreover, levels of the cell-to-cell junctional protein E-cadherin were suppressed by ribotoxic stress in both allograft and xenograft spheroids. In conclusion, the radiomimetic microbial ribotoxins induced structural defects in CRC cell spheroids via retardation of migration and cell-cell junction in the formation of three-dimensional structures, and provides a basis for the mechanism of pharmacological radiomimetic anticancer actions as an alternate to radiotherapy against cancer.

• Korean Journal of Optics and Photonics
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• v.32 no.5
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• pp.235-243
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• 2021

Photobiomodulation (PBM)-based therapy, which uses a phenomenon in which a light source of a specific wavelength band promotes ATP production in mitochondria, has attracted much attention in the fields of biology and medicine because of its effects on wound healing, inflammation reduction, and pain relief. Research on PBM-based therapy has mainly used lasers and light-emitting diodes (LEDs) as light sources and, despite the advantages of organic light-emitting diodes (OLEDs), there have been only a few cases where OLEDs were used in PBM-based therapy. In this research, the skin-care effect of PBM was analyzed using red (λ = 620 nm), green (λ = 525 nm), and blue (λ = 455 nm) OLED lighting modules, and was compared to the PBM effect of LEDs. We demonstrated the PBM-based skin-care effect of the red, green, blue OLED lighting modules by measuring the increase in the amount of collagen type-1 synthesis, the inhibition of melanin synthesis, and the suppression of nitric oxide generation, respectively.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.14 no.3
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• pp.184-192
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• 2021

Domestic agriculture is facing real problems, such as a decrease in the population in rural areas, a shortage of labor due to an aging population, and increased risks due to the deepening of climate change. Smart farming technology is being developed to solve these problems. In the development of smart agricultural technology, irrigation control plays an important role in creating an optimal growth environment and is an important issue in terms of environmental protection. This paper is about the study of collecting and analyzing the rhizosphere environmental data of domestic paprika farms for the purpose of improving the quality of crops, reducing production costs, and increasing production. Irrigation control modeling presented in this paper Control modeling is to graphically present changes in a medium weight, feed, and drainage due to regional climatic features. To derive the graph, the parameters were determined through data collection and analysis, and the suggested irrigation control modeling method was applied to the collected rhizosphere environmental data to control irrigation in 6 regions (Gangwon-do, Chungnam, Jeonbuk, Jeonnam, Gyeongbuk, and Gyeongnam). The parameters were obtained and graphs were derived from them. After that, a study was conducted to analyze the derived parameters to verify the validity of the irrigation control modeling method and to correlate them with climatic features (average temperature and precipitation).

• Natural Product Sciences
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• v.29 no.2
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• pp.74-82
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• 2023

Nepeta sibirica L. or Siberian catmint is a medicinal plant species used in Mongolian traditional medicine for curing human different disorders and veterinary practices. The previous study of the whole plant concentrated on the determination of its essential oil composition and reported that the major ones are sesquiterpenes, including nepetalactone. The aim of this study was to reveal a new biological activity of the above-ground parts of N. sibirica L. and compare the activity of different extracts correlating with the content of biologically active compounds and evaluate their toxicity. For this purpose, anti-oxidative and acetylcholinesterase inhibitory activities of the above-ground parts of N. sibirica L. aqueous and ethanol (EtOH) (40%, 70%) extracts were assayed spectrophotometrically. The aqueous extract showed positive anti-oxidative activity by both tested DPPH and FRAP assays with IC₅₀ 134.24 ± 1.42 mg/mL and FRAP value 1385.15 ± 8.12 µmol/L at 200 ㎍/mL, in contrast to 40% and 70% EtOH extracts. The 70% EtOH extract presented the highest acetylcholinesterase inhibitory activity (IC₅₀ 77.29 ± 0.38 mg/mL) followed by 40% EtOH extract (176.72 ± 0.35 mg/mL) and aqueous extract (275.41 ± 0.23 mg/mL). Total phenolics were found to be gallic acid equivalent, % 3.74 ± 0.05 (70% EtOH), 3.94 ± 0.04 (40% EtOH), and 3.79 ± 0.16 (aqueous), whereas the total flavonoids as a rutin equivalent, % as 2.01 ± 0.12, 1.44 ± 0.17 and 1.99 ± 0.02, each. The aqueous extract showed the best anti-oxidative and lowest activity against the acetylcholinesterase; however, the 70% EtOH extract showed the opposite effects than that of the aqueous. No mortality incidence was visible at various doses, indicating that the oral median lethal dose of aqueous and 70% EtOH extracts were considered greater than 5000 mg/kg. N. sibirica L. belongs to the non-toxic category of the OECD 423 classification.

• Journal of the Korean Society of Safety
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• v.35 no.1
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• pp.62-69
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• 2020

Most people suffer from stress during day life because modernized society is very complex and changes fast. Because stress can affect to many kind of physiological phenomena it is even considered as a disease. Therefore, it should be detected earlier, then must be released. When a person is being stressed several bio-signals such as heart rate, etc. are changed. So, those can be detected using medical electronics techniques. In this paper, stress assessment system is studied using random forest algorithm based on heart rate, RR interval and Galvanic skin response. The random forest model was trained and tested using the data set obtained from the bio-signals. It is found that the stress assessment procedure developed in this paper is very useful.

• 한국약용작물학회:학술대회논문집
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• 2011.04a
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• pp.220-221
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• 2011

• Journal of Microbiology and Biotechnology
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• v.16 no.11
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• pp.1837-1840
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• 2006

Because there are no unified nomenclature systems for either GES-type or IBC-type extended-spectrum ${\beta}-lactamases$ (ESBLs), we propose a unified and definitive nomenclature system for GES/IBC-type ESBLs. This proposed nomenclature update is greatly helpful in two points: (i) it would not confuse microbiologists studying GES-type ESBLs, fundamentally preventing misleading nomenclature of these antibiotic resistance genes, and (ii) the definitive renaming of GES/IBC-type ESBLs can help some researchers to correctly designate new GES-type ESBLs such as novel enzymes identified trom some nationwide surveys.