• Title/Summary/Keyword: bias reference

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A Systematic Review and Meta-analysis of Acupuncture Trials in Republic of Korea that Used Sham Acupuncture as a Control Group (거짓침을 대조군으로 사용한 국내 침 임상시험에 대한 체계적 고찰과 메타분석)

  • Kim, Jung-Eun;Kang, Kyung-Won;Kim, Tae-Hun;Lee, Seung-Hoon;Kim, Joo-Hee;Baek, Seung-Min;Choi, Sun-Mi
    • Journal of Acupuncture Research
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    • v.28 no.6
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    • pp.1-17
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    • 2011
  • Objectives : This study aimed to review randomized controlled trials of acupuncture performed in South Korea that used sham acupuncture as a control group. Methods : The following databases were searched through the end of September 2011: Koreanstudies information service system (KISS), Korean medical database (KMbase), national discovery OR science leaders (NDSL), oriental medicine advance searching integrated system (OASIS), and research information service system (RISS). The following search terms were used: acupuncture AND (sham or placebo). The reference lists of searched articles and Korea institute of oriental medicine (KIOM) reports(2005~2009) were identified. The following data were extracted: year/first author, disease, number of participants, blinding, intervention, outcome, and result. Where appropriate, we performed meta-analysis. The methodological quality was assessed according to the Jadad scale and 'risk of bias' by Cochrane Handbook procedure. Results : Twenty-nine studies were included in this review. In eighteen studies, penetrating sham controls were used as the control intervention, whereas the remaining eleven studies adopted non-penetrating sham controls such as the Park Sham Device or blunt auricular acupuncture. Nine studies showed statistically significant difference in outcomes. Twelve studies concerning insomnia after stroke, chronic tension-type headache, idiopathic Parkinson's disease, Hwa-Byung, and smoking cessation were included in meta-analysis. A meta-analysis of insomnia after stroke only found significant difference(MD -4.31, 95% Cl -6.19 to -2.42, $p$<0.00001). In general, all of the studies showed low methodological quality(Jadad score: mean 2.1). Risk of bias by Cochrane Handbook procedure varied. Conclusions : The results of this study could not suggest conclusive evidence that acupuncture is more effective than sham acupuncture in several diseases. In the future, more studies with rigorous acupuncture trials using sham controls should be conducted.

Level Shifts and Long-term Memory in Stock Distribution Markets (주식유통시장의 층위이동과 장기기억과정)

  • Chung, Jin-Taek
    • Journal of Distribution Science
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    • v.14 no.1
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    • pp.93-102
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    • 2016
  • Purpose - The purpose of paper is studying the static and dynamic side for long-term memory storage properties, and increase the explanatory power regarding the long-term memory process by looking at the long-term storage attributes, Korea Composite Stock Price Index. The reason for the use of GPH statistic is to derive the modified statistic Korea's stock market, and to research a process of long-term memory. Research design, data, and methodology - Level shifts were subjected to be an empirical analysis by applying the GPH method. It has been modified by taking into account the daily log return of the Korea Composite Stock Price Index a. The Data, used for the stock market to analyze whether deciding the action by the long-term memory process, yield daily stock price index of the Korea Composite Stock Price Index and the rate of return a log. The studies were proceeded with long-term memory and long-term semiparametric method in deriving the long-term memory estimators. Chapter 2 examines the leading research, and Chapter 3 describes the long-term memory processes and estimation methods. GPH statistics induced modifications of statistics and discussed Whittle statistic. Chapter 4 used Korea Composite Stock Price Index to estimate the long-term memory process parameters. Chapter 6 presents the conclusions and implications. Results - If the price of the time series is generated by the abnormal process, it may be located in long-term memory by a time series. However, test results by price fixed GPH method is not followed by long-term memory process or fractional differential process. In the case of the time-series level shift, the present test method for a long-term memory processes has a considerable amount of bias, and there exists a structural change in the stock distribution market. This structural change has implications in level shift. Stratum level shift assays are not considered as shifted strata. They exist distinctly in the stock secondary market as bias, and are presented in the test statistic of non-long-term memory process. It also generates an error as a long-term memory that could lead to false results. Conclusions - Changes in long-term memory characteristics associated with level shift present the following two suggestions. One, if any impact outside is flowed for a long period of time, we can know that the long-term memory processes have characteristic of the average return gradually. When the investor makes an investment, the same reasoning applies to him in the light of the characteristics of the long-term memory. It is suggested that when investors make decisions on investment, it is necessary to consider the characters of the long-term storage in reference with causing investors to increase the uncertainty and potential. The other one is the thing which must be considered variously according to time-series. The research for price-earnings ratio and investment risk should be composed of the long-term memory characters, and it would have more predictability.

Multi-channel Transimpedance Amplifier Arrays in Short-Range LADAR Systems for Unmanned Vehicles (무인차량용 단거리 라이다 시스템을 위한 멀티채널 트랜스임피던스 증폭기 어레이)

  • Jang, Young Min;Kim, Seung Hoon;Cho, Sang Bock;Park, Sung Min
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.12
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    • pp.40-48
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    • 2013
  • This paper presents multi-channel transimpedance amplifier(TIA) arrays in short-range LADAR systems for unmanned vehicles, by using a 0.18um CMOS technology. Two $4{\times}4$ channel TIA arrays including a voltage-mode INV-TIA and a current-mode CG-TIA are introduced. First, the INV-TIA consists of a inverter stage with a feedback resistor and a CML output buffer with virtual ground so as to achieve low noise, low power, easy current control for gain and impedance. Second, the CG-TIA utilizes a bias from on-chip bandgap reference and exploits a source-follower for high-frequency peaking, yielding 1.26 times smaller chip area per channel than INV-TIA. Post-layout simulations demonstrate that the INV-TIA achieves 57.5-dB${\Omega}$ transimpedance gain, 340-MHz bandwidth, 3.7-pA/sqrt(Hz) average noise current spectral density, and 2.84mW power dissipation, whereas the CG-TIA obtains 54.5-dB${\Omega}$ transimpedance gain, 360-MHz bandwidth, 9.17-pA/sqrt(Hz) average noise current spectral density, and 4.24mW power dissipation. Yet, the pulse simulations reveal that the CG-TIA array shows better output pulses in the range of 200-500-Mb/s operations.

Assessment of Forest Biomass using k-Neighbor Techniques - A Case Study in the Research Forest at Kangwon National University - (k-NN기법을 이용한 산림바이오매스 자원량 평가 - 강원대학교 학술림을 대상으로 -)

  • Seo, Hwanseok;Park, Donghwan;Yim, Jongsu;Lee, Jungsoo
    • Journal of Korean Society of Forest Science
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    • v.101 no.4
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    • pp.547-557
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    • 2012
  • This study purposed to estimate the forest biomass using k-Nearest Neighbor (k-NN) algorithm. Multiple data sources were used for the analysis such as forest type map, field survey data and Landsat TM data. The accuracy of forest biomass was evaluated with the forest stratification, horizontal reference area (HRA) and spatial filtering. Forests were divided into 3 types such as conifers, broadleaved, and Korean pine (Pinus koriansis) forests. The applied radii of HRA were 4 km, 5 km and 10 km, respectively. The estimated biomass and mean bias for conifers forest was 222 t/ha and 1.8 t/ha when the value of k=8, the radius of HRA was 4 km, and $5{\times}5$ modal was filtered. The estimated forest biomass of Korean pine was 245 t/ha when the value of k=8, the radius of HRA was 4km. The estimated mean biomass and mean bias for broadleaved forests were 251 t/ha and -1.6 t/ha, respectively, when the value of k=6, the radius of HRA was 10 km. The estimated total forest biomass by k-NN method was 799,000t and 237 t/ha. The estimated mean biomass by ${\kappa}NN$method was about 1t/ha more than that of filed survey data.

A Study on Pseudo-Range Correction Modeling in order to Improve DGNSS Accuracy (DGNSS 위치정확도 향상을 위한 PRC 보정정보 모델링에 관한 연구)

  • Sohn, Dong Hyo;Park, Kwan Dong
    • Journal of Korean Society for Geospatial Information Science
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    • v.23 no.4
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    • pp.43-48
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    • 2015
  • We studied on pseudo-range correction(PRC) modeling in order to improve differential GNSS(DGNSS) accuracy. The PRC is the range correction information that provides improved location accuracy using DGNSS technique. The digital correction signal is typically broadcast over ground-based transmitters. Sometimes the degradation of the positioning accuracy caused by the loss of PRC signals, radio interference, etc. To prevent the degradation, in this paper, we have designed a PRC model through polynomial curve fitting and evaluated this model. We compared two quantities, estimations of PRC using model parameters and observations from the reference station. In the case of GPS, the average is 0.1m and RMSE is 1.3m. Most of GPS satellites have a bias error of less than ${\pm}1.0m$ and a RMSE within 3.0m. In the case of GLONASS, the average and the RMSE are 0.2m and 2.6m, respectively. Most of satellites have less than ${\pm}2.0m$ for a bias error and less than 3.0m for RMSE. These results show that the estimated value calculated by the model can be used effectively to maintain the accuracy of the user's location. However;it is needed for further work relating to the big difference between the two values at low elevation.

Long-term forecasting reference evapotranspiration using statistically predicted temperature information (통계적 기온예측정보를 활용한 기준증발산량 장기예측)

  • Kim, Chul-Gyum;Lee, Jeongwoo;Lee, Jeong Eun;Kim, Hyeonjun
    • Journal of Korea Water Resources Association
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    • v.54 no.12
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    • pp.1243-1254
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    • 2021
  • For water resources operation or agricultural water management, it is important to accurately predict evapotranspiration for a long-term future over a seasonal or monthly basis. In this study, reference evapotranspiration forecast (up to 12 months in advance) was performed using statistically predicted monthly temperatures and temperature-based Hamon method for the Han River basin. First, the daily maximum and minimum temperature data for 15 meterological stations in the basin were derived by spatial-temporal downscaling the monthly temperature forecasts. The results of goodness-of-fit test for the downscaled temperature data at each site showed that the percent bias (PBIAS) ranged from 1.3 to 6.9%, the ratio of the root mean square error to the standard deviation of the observations (RSR) ranged from 0.22 to 0.27, the Nash-Sutcliffe efficiency (NSE) ranged from 0.93 to 0.95, and the Pearson correlation coefficient (r) ranged from 0.97 to 0.98 for the monthly average daily maximum temperature. And for the monthly average daily minimum temperature, PBIAS was 7.8 to 44.7%, RSR was 0.21 to 0.25, NSE was 0.94 to 0.96, and r was 0.98 to 0.99. The difference by site was not large, and the downscaled results were similar to the observations. In the results of comparing the forecasted reference evapotranspiration calculated using the downscaled data with the observed values for the entire region, PBIAS was 2.2 to 5.4%, RSR was 0.21 to 0.28, NSE was 0.92 to 0.96, and r was 0.96 to 0.98, indicating a very high fit. Due to the characteristics of the statistical models and uncertainty in the downscaling process, the predicted reference evapotranspiration may slightly deviate from the observed value in some periods when temperatures completely different from the past are observed. However, considering that it is a forecast result for the future period, it will be sufficiently useful as information for the evaluation or operation of water resources in the future.

Classification and Characterization of Exposure Rating in Humidifier Disinfectants through Calculation of PHMG Reference Concentration (PHMG (polyhexamethylene guanidine) 흡입독성참고치 산출을 통한 가습기살균제 노출등급 분류 및 특성)

  • Kim, Eunchae;Ryu, Hyeonsu;Park, Jinhyeon;Choe, Youngtae;Heo, Jung;Lee, Seula;Jo, Eun-Kyung;Choi, Yoon-Hyeong;Cho, Mansu;Yang, Wonho
    • Journal of Environmental Health Sciences
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    • v.46 no.3
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    • pp.335-343
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    • 2020
  • Objectives: The Korean Ministry of Environment has identified cases of people suspected of suffering lung disease potentially caused by polyhexamethylene guanidine (PHMG) used in humidifier disinfectants (HDs). Exposure assessment for the HDs was conducted using a questionnaire during face-to-face interview. The main purposes of this study were to develop a methodology to effectively classify levels of exposure to HDs based on a questionnaire. Methods: We first identified the overall participants' exposure characteristics by HD exposure levels; Second, we selected misclassified subjects and investigated characteristics of overestimated and underestimated subjects, focusing on exposure cases to PHMG-containing HDs. An inhalation reference concentration (RfC) for PHMG was produced on the basis of inhalation toxicity values. We made a cross-tabulation of the exposure classes (Exposure classes 1-to-4) by clinical classes based on the RfC. When the value of the exposure class minus the clinical class was 0 or 1, we assumed these were true values. When the value was ≥2 and ≤ -2, we assigned these cases to the overestimation group and underestimation group, respectively. Results: The overestimated group may have already recovered and responded excessively due to psychological anxiety or in order to receive compensation. On the other hand, relatively high mortality rates and surrogate responses for those under 10 years of age may have resulted in inaccurate exposure assessment for underestimated groups. For the characteristics of exposure, it was shown that for the underestimated group, the exposure was relatively weaker than the overestimated group, even though a high overall clinical rating was determined. Conclusions: This study may suggest ways to reduce bias and overcome the limitations of current HD exposure assessment.

A Study on the Design of a Beta Ray Sensor for True Random Number Generators (진성난수 생성기를 위한 베타선 센서 설계에 관한 연구)

  • Kim, Young-Hee;Jin, HongZhou;Park, Kyunghwan;Kim, Jongbum;Ha, Pan-Bong
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.12 no.6
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    • pp.619-628
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    • 2019
  • In this paper, we designed a beta ray sensor for a true random number generator. Instead of biasing the gate of the PMOS feedback transistor to a DC voltage, the current flowing through the PMOS feedback transistor is mirrored through a current bias circuit designed to be insensitive to PVT fluctuations, thereby minimizing fluctuations in the signal voltage of the CSA. In addition, by using the constant current supplied by the BGR (Bandgap Reference) circuit, the signal voltage is charged to the VCOM voltage level, thereby reducing the change in charge time to enable high-speed sensing. The beta ray sensor designed with 0.18㎛ CMOS process shows that the minimum signal voltage and maximum signal voltage of the CSA circuit which are resulted from corner simulation are 205mV and 303mV, respectively. and the minimum and maximum widths of the pulses generated by comparing the output signal through the pulse shaper with the threshold voltage (VTHR) voltage of the comparator, were 0.592㎲ and 1.247㎲, respectively. resulting in high-speed detection of 100kHz. Thus, it is designed to count up to 100 kilo pulses per second.

Copper Isotope Measurements Using a Neptune MC-ICP-MS (다검출기 유도결합 플라즈마 질량분석기를 이용한 구리 동위원소 분석법)

  • Park, Sanghee;Ryu, Jong-Sik;Shin, Hyung Seon;Kil, Youngwoo;Jo, Yunsoo
    • Journal of the Mineralogical Society of Korea
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    • v.29 no.4
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    • pp.221-227
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    • 2016
  • Copper is an essential transition metal involving in various biogeochemical processes. With the recent advances in analytical techniques and mass spectrometry, such as MC-ICP-MS, it is possible to measure Cu isotopes, which allows us to understand various biogeochemical processes in detail. Nonetheless, few studies have been performed in South Korea. In this study, we compared two purification methods previously reported using an anion exchange resin ($AG^{(R)}$ MP-1M), developed the best method in our lab environment, and then verified it by measuring Cu isotopic compositions in two USGS geological reference materials (BHVO-2 and BIR-1a). Although all matrix cations causing mass bias were effectively removed through both two methods with the yield of better than 95%, the method using the mixture of HCl and $H_2O_2$ only displays Cu isotopic compositions, in excellent agreement with reported values within the error. The method developed in this study is expected to be commonly applied to earth and environmental sciences.

A Comparative Study of Tight Skirt Sewing Methods -Focusing on the Sewing Methods Shown in Reference Text Books on Clothing Configuration and used in Domestic Consumer Products- (타이트스커트 봉제방법에 관한 비교 연구 -의복구성 교재와 국내 브랜드 제품을 중심으로-)

  • Kim, Sun-Young;Choi, Young-Soon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.31 no.11
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    • pp.1510-1519
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    • 2007
  • This comparative study analyzes and compares tight skirt sewing methods which are found in the clothing configuration reference text books available in contemporary universities and which are used in commercially-available domestic consumer products. The study samples included 15 text books and 12 tight skirt consumer products of different brands on sale at three department stores in Seoul each of which had a belt, a back-centered zipper, and back double slits. The findings of the study are summarized as follows: First, text books mainly show very basic sewing methods of using zippers on both sides of the straight-lined waist belt. This indicates that it is necessary for such methods to be complemented so that they cover a recent variety of designs, materials, and sewing machines. For consumer products, the main sewing method is to use a curved waist belt and a console zipper in silhouette running across half the hipbone. Second, consumer products employ three different types of cutting and sewing methods for putting an inseam on the center of the back slit part: to leave the whole inseam hemmed in the back center, to cut the left side of the inseam to the upper part of the back slit, and to cut the inseam to both the upper parts of the back slit. However, a method shown in most of the sampled text books is to cut the inseam of the back center to both the upper parts of the back slit. Third, the way of finishing a bottom edge hem in the text books is to do slip-stitch, herringbone stitch, and slinting hemming, in order after doing over-lock stitch, or to cut the hem on the bias and then slip-stitch, while for the consumer products the most frequently used sewing method is to finish the bottom edge hem by doing secoui-stitch. Finally, while in the text books the method of stitching darts and tucks is used for lining, the main lining method used in consumer products is to make tucks only. Also in the way of stitching the side seams of lining or the seams of the back center, there is a difference between the two sample groups of text books and the consumer products: while the former suggests using both open seams and over-lock stitch, the latter is found to finish the seams using an over-lock stitch only.