• Genomics & Informatics
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• v.15 no.1
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• pp.38-47
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• 2017

Research into new methods for identifying highly expressed genes in anonymous genome sequences has been going on for more than 15 years. We presented here an alternative approach based on modified score of relative codon usage bias to identify highly expressed genes in crenarchaeal genomes. The proposed algorithm relies exclusively on sequence features for identifying the highly expressed genes. In this study, a comparative analysis of predicted highly expressed genes in five crenarchaeal genomes was performed using the score of Modified Relative Codon Bias Strength (MRCBS) as a numerical estimator of gene expression level. We found a systematic strong correlation between Codon Adaptation Index and MRCBS. Additionally, MRCBS correlated well with other expression measures. Our study indicates that MRCBS can consistently capture the highly expressed genes.

• Journal of Distribution Science
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• v.12 no.9
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• pp.83-93
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• 2014

Purpose - This study attempted to identify any influencing relationships, between the antecedent variables and the members' innovative work behavior, which were expected to influence organizational performance based on the extended theory of planned behavior (ETPB). Research design, data, and methodology - The survey was conducted on SMEs in Seoul and its metropolitan area. A total of 158 copies of effective questionnaires were used and were analyzed through correlation analysis, regression analysis, and multiple regression. Results - Self-efficacy, value, intrinsic motivation, and self-enhancing bias have been found to have a positive relationship with innovative work behavior. In addition, transformational leadership was found to moderate the existence of a statistically significant negative influence between value, intrinsic motivation, and innovative work behavior. Conclusions - The results suggest that leaders will be successful in winning members' trust through conducting their behaviors in accordance with the applicable ethical and moral standards and through their fair, transparent, and legitimate management practices with an attitude of 'taking the initiative and setting an example', and this will help solve such problems.

• Journal of the Korea Society for Simulation
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• v.7 no.1
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• pp.27-37
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• 1998

Simulation output is generally stochastic and autocorrelated, and includes the initial condition bias. To exclude the bias, the determination of truncation point has been one of important issues for the steady-state simulation output analysis. In this paper, two methods are presented for detection of truncation point in order to estimate efficiently the steady-state measure of simulation output. They are based on the Euclidean distance equation, and the backpropagation algorithm in Neural Networks. The experimental results obtained by M/M/1 and M/M/2 show that the proposed methods are very promising with respect to coverage and relative bias. The methods could be used for the on-line analysis of simulation outputs.

• Science of Emotion and Sensibility
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• v.27 no.3
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• pp.107-120
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• 2024

Individuals with high social anxiety (HSA) exhibit an excessive bias toward socially threatening stimuli. The purpose of this study is to identify attentional bias patterns toward threat stimuli in people with HSA (but not those with social anxiety disorder, SAD). Furthermore, our goal was to investigate neural biomarkers that can predict these attentional bias patterns in people with HSA. We collected and analyzed behavioral data on attentional bias patterns, anxiety levels, social anxiety levels, and the frontal region theta/beta ratio using an electroencephalogram (EEG) from 33 neurotypical female adults. For analysis, we divide participants into two categories: (1) HSA and (2) low social anxiety (LSA). The results showed that both the HSA and LSA groups had an initial attentional bias toward emotional faces, but only the HSA group had a prolonged attentional bias toward angry faces. Furthermore, a significant positive correlation was found between the attentional bias score and the social anxiety score. Additionally, a decreased theta/beta ratio significantly explained the degree of attention bias in the HSA group and was a significant predictor of attentional bias in this group. Overall, this study finds that individuals with HSA exhibit similar patterns of attentional bias to those found in patients with SAD, as identified in previous research. Moreover, the findings suggest that a decreased frontal theta/beta ratio is associated with excessive attentional biases in HSA individuals. These findings contribute to our understanding of the behavioral and neurological pathophysiology associated with high levels of social anxiety, potentially assisting in the development of appropriate evaluation methods and the determination of the effect of the treatment intervention.

• Journal of Physiology & Pathology in Korean Medicine
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• v.34 no.6
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• pp.299-308
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• 2020

This study aimed to evaluate the effects of Chuna therapy for Sciatica. We searched the following 16 online databases without a language restriction (Pubmed, Cochrane, Embase, CINAHL, Ovid, Kmbase, RISS, NDSL, OASIS, KISS, KNAL, KTKP, DBpia, CNKI, Wangfang, J-stage) to find randomized controlled clinical trials that used Chuna therapy for Sciatica. The methodological quality of randomized controlled clinical trials (RCTs) were assessed using the Cochrane risk of bias tool and meta-analysis were performed. Among 496 articles that were searched, 15 RCTs were finally selected for systematic review. 14 studies showed that Chuna therapy has positive effect on sciatica. Two studies noted that there were side effects, and the difference between the intervention group and the control group was statistically insignificant. One study noted no side effects and the rest of the study, there was no mention of side effects. Meta-analysis showed positive results for Chuna single therapy in terms of efficiency rate compared to painkiller, herb medicine excepting acupuncture. When comparing Chuna therapy plus acupuncture and acupuncture, Chuna therapy plus acupuncture had a more positive result than acupuncture in terms of efficiency rate. Cochrane Risk of Bias (RoB)evaluation method, most of the studies's selection, performance, detection and reporting bias were unclear. The studies showed that Chuna therapy can significantly effective on sciatica. However, most of the studies's Risk of Bias included in the analysis were not low enough. In the future, to prove the level of evidence of Chuna therapy, more high-quality studies will be needed.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.60 no.12
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• pp.2311-2317
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• 2011

In this paper, we study the temperature change of a ${\mu}$-bolometer focal plane array with a capacitive transimpedance amplifier bias cancellation circuit. Thermal analysis is essential to understand the performance of a ${\mu}$-bolometer focal plane array, and to improve the temperature stability of a focal plane array characteristics. In this study, the thermal analyses of a ${\mu}$-bolometer and its two reference detectors are carried out as a function of time. The analyses are done with the $30{\mu}m$ pitch $320{\times}240$ focal plane array operating of 60 Hz frame rate and having a columnwise readout. From the results, the temperature increase of a ${\mu}$-bolometer in FPA by an incident IR is estimated as $0.689^{\circ}C$, while the temperature increase by a pulsed bias as $7.1^{\circ}C$, which is about 10 times larger than by IR. The temperature increase of a reference detector by a train of bias pulses may be increased much higher than that of an active ${\mu}$-bolometer. The suppression of temperature increase in a reference bolometer can be done by increasing the thermal conductivity of the reference bolometer, in which the selection of thermal conductivity also determines the range of CTIA output voltage.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.35D no.9
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• pp.35-41
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• 1998

A transient chirp measurement was used to analyze the chirping characteristics of modulator integrated DFB (MI-DFB) laser module. This method measures the wavelength change due to a small variation in modulation with bias. The measurement system includes a monochrometer and digitizing oscilloscope. The chirping characteristics due to packaging influences can also be accounted for. The chirp parameter calculated using this method was compared with the peak-to peak chirp. They showed the same tendency with modulator bias voltage. These results can be used as a reference when optimizing system parameters.

• Parasites, Hosts and Diseases
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• v.55 no.2
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• pp.175-183
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• 2017

Codon usage bias (CUB) is a unique property of genomes and has contributed to the better understanding of the molecular features and the evolution processes of particular gene. In this study, genetic indices associated with CUB, including relative synonymous codon usage and effective numbers of codons, as well as the nucleotide composition, were investigated in the Clonorchis sinensis tyrosinase genes and their platyhelminth orthologs, which play an important role in the eggshell formation. The relative synonymous codon usage patterns substantially differed among tyrosinase genes examined. In a neutrality analysis, the correlation between $GC_{12}$ and $GC_3$ was statistically significant, and the regression line had a relatively gradual slope (0.218). NC-plot, i.e., $GC_3$ vs effective number of codons (ENC), showed that most of the tyrosinase genes were below the expected curve. The codon adaptation index (CAI) values of the platyhelminth tyrosinases had a narrow distribution between 0.685/0.714 and 0.797/0.837, and were negatively correlated with their ENC. Taken together, these results suggested that CUB in the tyrosinase genes seemed to be basically governed by selection pressures rather than mutational bias, although the latter factor provided an additional force in shaping CUB of the C. sinensis and Opisthorchis viverrini genes. It was also apparent that the equilibrium point between selection pressure and mutational bias is much more inclined to selection pressure in highly expressed C. sinensis genes, than in poorly expressed genes.

• The Journal of the Acoustical Society of Korea
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• v.20 no.7
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• pp.94-100
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• 2001

When using a sample covariance matrix data in paucity of snapshots, adaptive matched field processing will have problem in inverting covariance matrix due to the rank deficiency. The general solutions are diagonal loading and eigenanalysis methods, but there is a significant bias in the power output. This paper presents a quantitative study of bias of power output and the performance of source localization through the simulation and the measured data analysis in fixed source case using the diagonal loading method for the minimum variance processor. Results show that the bias in power output is reduced and the performance of source localization is improved when the number of snapshots is greater than the number of array sensors.

• Journal of the Korean Home Economics Association
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• v.51 no.1
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• pp.75-87
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• 2013

The purpose of this study was to explore the relationship between the preschoolers' hostile attributional bias and the narrative representation profiles. Forty five 4-year-old preschoolers (24 boys, 21 girls) participated in this study. In order to measure the children's narrative responses, MacArthur Story Stem Battery (MSSB) was used, and "a cartoon-based social perception task" was used to obtain preschoolers' hostile attributional bias. The data were analyzed using descriptive statistics and cluster analysis. The results were as follows. First, the rate of hostile attributional style of the subjects was 28.89%. Second, four profiles regarding the narrative representations of 4-year olds were found including: Prosocial (33.3%), Constrained (42.2%), Anxious/Restricted (6.7%), and Dysregulated (17.8%). Third, the rate of preschoolers' hostile attributional style differed by the preschoolers' narrative representation profile. Children with a Prosocial profile showed a less hostile attributional style than children with an Anxious/Restricted profile and Dysregulated profile. In conclusion, preschoolers' hostile attributional bias is related to the narrative representation profile.