• 대한기관식도과학회:학술대회논문집
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• 대한기관식도과학회 1993년도 제27차 학술대회 초록집
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• pp.96-96
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• 1993

두경부 종양의 1%를 차지하는 타액선 종양은 조직학적인 다양성 때문에 진단과 치료결정이 어렵고 자세한 병력이 중요하다. 1987년 1월부터 1992년 12월까지 본원 이비인후과에서 조직학적으로 확진된 타액선 종양 70례를 대상으로 후향적인 방법으로 성별 분포, 연령별 분포, 부위별 분포, 양성종양의 크기, 병리조직학적 분류, 중상발현 기간, 임상증상, 경부 림프절전이, 병기별 분포, 치료, 안면신경마비 및 재발 둥을 비교 분석하여 다음과 같은 결과를 얻었다. 1) 이하선에 35례(50%), 악하선에 16례(23%), 부타액선에 19례(27%) 발생했다. 2) 양성종양이 55례(79%), 악성종양이 15례(21%) 였고, 양성종양은 다형성선종이 49례(89%), 악성종양은 선낭포암이 6례(40%)로 가장 많았다. 3)증상발현 기간은 1-5년이 29례(41%)로 가장 많았다. 4) 이하선과 악하선 수술후 안면신경마비가 9례(18%)에서 있었고, 재발은 4례(6%)에서 발생하였다.

• Journal of Veterinary Science
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• 제23권6호
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• pp.70.1-70.13
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• 2022

Background: Fat stranding is a non-specific finding of an increased fat attenuation on computed tomography (CT) images. Fat stranding is used for detecting the underlying lesion in humans. Objectives: To assess the clinical significance of fat stranding on CT images for identifying the underlying cause in dogs and cats. Methods: In this retrospective study, the incidence, location, extent, distribution, and pattern of fat stranding were assessed on CT studies obtained from 134 cases. Results: Fat stranding was found in 38% (51/134) of all cases and in 35% (37/107) of tumors, which was significantly higher in malignant tumors (44%) than benign tumors (12%). Moreover, fat stranding was found in more than two areas in malignant tumors (16/33) and in a single area in benign tumors (4/4). In inflammation, fat stranding was demonstrated in 54% (7/13) in a single area (7/7) as a focal distribution (6/7). In trauma, fat stranding was revealed in 50% (7/14) and most were in multiple areas (6/7). Regardless of the etiologies, fat stranding was always around the underlying lesion and a reticular pattern was the most common presentation. Logistic regression analysis revealed that multiple areas (p = 0.040) of fat stranding and a reticulonodular pattern (p = 0.022) are the significant predictors of malignant tumor. Conclusions: These findings indicated that CT fat stranding can be used as a clue for identifying the underlying lesion and can be useful for narrowing the differential list based on the extent and pattern.

• Journal of Chest Surgery
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• 제23권2호
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• pp.299-308
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• 1990

A review of 50 patients with primary mediastinal tumors or cysts has been done to evaluate clinical and pathological behavior of this heterogeneous group of tumors proved by either excision or biopsy from January 1980 to August 1989 at the cardiovascular department of surgery in Kyungpook National University Hospital. There were 30 males and 20 females in this series. The ages of patients ranged from 4 months to 64 years. The mean age of subjects was 30.4 years. Neurogenic tumors [14 cases, 28%] and teratoma [14 cases, 28%] were most frequently encountered and followed by thymoma [10 cases, 20%] and benign cysts [4 cases, 8%]. The anatomic location of the primary mediastinal tumors or cysts was classified as anterior mediastinum and middle or visceral mediastinum and paravertebral or costovertebral mediastinum on the basis of the Shields’ proposition. In 32 patients[64%], the tumors or cysts were located in anterior mediastinum and in 13 patients[26%], the tumors or cysts were located in paravertebral or costovertebral mediastinum. And the rest 5 patients[10%] had middle or visceral mediastinal tumors or cysts. One of the characteristic features of primary mediastinal tumors or cysts is that some mediastinal tumors or cysts have their own preferred location in the mediastinum. In our series, all of the 14 patients with teratoma and 10 patients with thymoma had the anterior mediastinal location, while 13 of the 14 patients with neurogenic tumors had the paravertebral mediastinal location. 14 patients[28%] were asymptomatic and they all were discovered via so-called “Routine” chest x-ray examination. 39 of 50 patients[78%] were benign. 11 patients[22%] were malignant and they were all symptomatic. 40 patients[80%] were treated with complete resection. 5 patients[10%] were treated with partial resection : 2 of malignant thymoma, 3 of lipoma, neuroblastoma, primary squamous cell carcinoma. The rest 5 patients[10%] were only biopsied: 2 of undetermined malignancy and 3 of hemangioma, lymphoma, primary squamous cell carcinoma. 4 of the 10 patients were treated with combination of irradiation and chemotherapy. Postoperative complications were as followings: Horner’s syndrome [4cases, ado], respiratory failure [3 cases, 6%], pleural effusion[3 cases, 6%], Wound infection[2 cases, 4%] and bleeding, pneumothorax, empyema. There were 5 postoperative deaths [10%]. One patient with neuroblastoma died from intraoperative massive bleeding, 3 patients died early postoperatively from respiratory failure with undetermined malignancy died late postoperatively from congestive heart failure due to direct invasion of the tumor to the heart.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권3호
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• pp.301-304
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• 2000

혈관외피세포종은 구강 내에서 매우 드물게 발생되는 종양으로 양성과 악성의 구분이 매우 어려운 종양이다. 이의 치료는 외과적인 완전 절제이나 오랜 시간이 지난 후에도 재발과 전이가 발생될 수 있으므로 술후 장기간의 주기적인 관찰을 요한다. 이에 저자 등은 30대 여자 환자의 협점막에 발생한 혈관외피세포종을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

• 치과방사선
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• 제19권1호
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• pp.89-101
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• 1989

The author observed and analyzed the age, sex, chief complaint and radiographic finding of sixty-one cases of benign odontogenic tumors seen in Yonsei Medical Center, for the period of Jan. 1979 to Aug. 1989. The results were as follows: 1. Benign odontogenic tumors of 61 cases included 52 cases (85.3%) of ameloblastoma and odontoma, and 9 cases of other lesions. Radiographically, the border of the lesions were well-defined. 2. Ameloblastoma constituting twenty-seven cases (44.3%) occurred the average age of 31.1 years and had a 3:1 male predominance. The most common complaint was swelling (20 cases, 74.0%) and followed by pain (13 cases, 48.2%). Radiographically, the most common site was mandibular body area (74.0%) and the lesions were mainly multiocular radiolucency; in 17 cases (63.0%) and unilocular radiolucent lesion were seen in 10 cases (37.0%). 16 cases (59.3%) showed the resorption of roots of adjacent teeth. 3. Odontoma constituting twenty-five cases (41.0%) discovered at the average age of 16.9 years and had a 3:2 male predominance. The most common complaint was delayed eruption of tooth (8 cases, 31.0%) and 7 cases (27.0%) detected on a routine radiograph of the area. Radiographically, 17 cases (68.0%) were of compound type and 8 were of complex variety and compound odontomas were common in the anterior maxilla, whereas complex odontomas occurred more frequently in the posterior mandible. 19 cases (76.0%) showed the impaction of adjacent teeth.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5565-5570
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• 2014

Objectives: This study aimed to characterize the histopathological pattern of thyroid lesions among Saudi patients and to highlight the age and gender variations of these lesions as base line data. Materials and Methods: We retrospectively analyzed the data from thyroid specimens received at the Department of Pathology, King Fahad Hospital, Madinah, Saudi Arabia from January 2006 to December 2013. Results: The 292 thyroidectomy specimens received during the study period came from 230 (78.8%) females and 62 (21.2%) males giving a female: male ratio of 3.7:1. Age of the patients ranged from 14 to 95 years with a mean age 39.7 years. Two hundred and eleven (72.3%) cases were found to be non-neoplastic and 81 (27.7%) cases were neoplastic. The non-neoplastic group included: colloid goiter, including both diffuse and nodular goiter (170 cases; 58.2%), nodular hyperplasia (28 cases; 9.6%), Hashimoto/chronic lymphocytic thyroiditis (12 cases; 4.1%), and Grave's disease (1 case; 0.3%). In neoplastic lesions, there were 7 benign tumors and 74 malignant tumors. Among the benign tumors, 5 were follicular adenomas and 2 were Hurthle cell adenomas. Papillary carcinoma was the commonest malignant tumor accounting for 87.8% of all thyroid malignancies, followed by lymphoma, follicular carcinoma and medullary carcinoma. The size of papillary carcinoma was more than 2 cm in 40 cases (76.9%). Conclusions: Non-neoplastic thyroid lesions were more common than neoplastic ones. Colloid goiter was the most common lesion. Follicular adenoma was the commonest benign tumor and papillary carcinoma was the commonest malignant lesion. There appears to be a slightly increased trend of papillary carcinoma diagnosis, most being diagnosed at an advanced stage.

• 대한두경부종양학회지
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• 제27권1호
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• pp.54-58
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• 2011

Objectives : There are many reports on attempts to minimize complications and recurrences of tumor by several techniques for benign parotid tumor resection. The purpose of our study is to find out meaning of procedure without identifying main trunk of facial nerve compared to conventional parotidectomy. Material and Methods : We classified 121 patients into two groups. Patients who were underwent superficial parotidectomy or partial superficial parotidectomy were included in idenitification group(IF group), and patients who were treated with conservative partial parotidectomy or extracapsular dissection without identification of main trunk of facial nerve were included in the non-identification group(NF group). We analyzed the location of tumor, operation time, mean drainage duration, complication, recurrence and cosmetic satisfaction in two groups. Results : NF group has shorter operation time and mean drainage duration than IF group, however there is no significant difference in complication and recurrence between two surgical techniques. The Cosmetic satisfaction was similar between two groups. Conclusion : Limited parotidectomy without finding main trunk of facial nerve may be reliable option for benign parotid tumors because it has advantages such as less operation time and mean drainage duration without increasing in recurrence or complication rate.

• Nuclear Medicine and Molecular Imaging
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• 제41권3호
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• pp.258-259
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• 2007

Benign metastasizing leiomyoma(BML) is a rare condition affecting women with a history of having undergone hysterectomy or myomectomy for a benign uterine fibroid, that is found to have metastasized to extrauterine sites, usually many years after hysterectomy. 1,2) Patient with BML almost always asymptomatic, although if the lesions are large enough, they can cause compressive symptoms. Among several hypothesis of pathogenesis, most plausible theory is that these tumors represent a true metastatic lesion but are very low-grade sarcoma. 3) Because the tumor is responsive to estrogen, menopause and pregnancy have slowed the growth of these lesion 4) and it seems reasonable to perform hysterectomy in patients with a uterine mass and, at the same time, perform oophorectomy for hormonal control. BML is an unusual cause of diffuse pulmonary nodules which should be considered in females with unexplained nodules and a history of surgery for uterine leiomyoma.

• Tuberculosis and Respiratory Diseases
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• 제40권5호
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• pp.575-583
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• 1993

연구배경 : 종격동 종양 및 낭종은 매년 100,000명당 1예의 빈도로 발생하는데 반수 정도에서 증상없이 우연히 발견되기도 하고 흉강내에서 인접한 주위 조직들을 압박하거나 침범함으로써 증상을 유발하기도 한다. 종격동 종양은 모든 연령층에서, 그리고 남녀간에 뚜렷한 차이 없이 고르게 발생하고 해부학적 구역에 따라 호발하는 종양이 다르며 양성 종양이라고 하더라도 가능한 초기에 적극적으로 절제하는 것이 권장되는 임상적인 특징을 보인다. 방법 : 연세대학교 의과대학 세브란스병원에서 1960년 1월부터 1992년 8월까지 병리조직학적으로 원발성 종격동 종양 및 낭종으로 확진된 344예를 대상으로 하여 발생 빈도와 발생 연령, 그리고 성별에 따른 빈도를 조사하였다. 그리고 진단 당시에 환자들이 주로 호소하였던 임상증상, 무증상의 빈도, 악성의 발생 빈도 및 치료 방법 등의 임상적인 양상들을 살펴보았다. 결과 : 전체 종격동 종양중 신경성 종양이 24.7%로 가장 많았고 기형유피종과 흉선종이 각 29.1%로 두번째로 많았다. 연령별 분포에서는 10세 미만에서 가장 적은 반면 나머지 연령층에서는 비교적 균등한 분포를 보였으며 전체적인 남녀 성비가 1.1:1로써 종격동 종양에서 남녀간의 차이는 유의하지 않은 것으로 관찰되었다. 신경성 종양은 후종격동에, 기형유피종과 임파종은 전종격동에, 그리고 흉선종은 전종격동에 호발하였으며 전체적으로 전부(52.0%)에서 가장 많이 관찰되었다. 내원 당시 환자들이 가장 많이 호소한 증상은 호흡곤란(27.7%)이었고 흉부 X-선상 종격동 종양이 우연히 발견될 때까지 전혀 증상이 없었던 경우가 19.5%를 차지하였다. 신경성 종양의 경우 27.1%, 기형유피종은 13.0%, 그리고 흉선종은 40.6%에서 악성의 양상을 보였으며 전체적으로 34.0%가 악성이었다. 대상 환자 344예중 42.4%에서 완전 또는 부분 절제가 시행되었고 13.6%에서 항암 화학요법이나 방사선 치료가 시행되었으며 43.9%는 조직 생검만이 시행되었는데 후자의 경우는 거의 대부분 1985년 이전의 경우이었다. 절제가 시행되었던 146예중 34예(23.3%)에서 수술후 30일 이내에 합병증이 발생하였는데 창상 감염이 6예로 가장 많았으며 농흉이 5예의 순이었고 여러 가지 신경의 손상은 12예 있었다. 결론 : 종격동 종양은 최근 빈도가 증가할 뿐만 아니라 치료에 있어 적극적인 절제의 경향을 보인다. 향후 정기적인 건강 검진의 보급 및 진단 수기의 발달로 더 많은 종격동 종양이 진단되리라고 기대되며 이로써 우리나라에서의 특징적인 임상 양상에 대한 연구가 필요하겠다.

• Journal of Chest Surgery
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• 제25권7호
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• pp.719-722
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• 1992

Two cases of benign mediastinal tumor were treated by complete resection under the video-thoracoscopic guidance. The procedure has been performed on the 2 patients, allowing definite treatment and was less invasive than standard surgical treatment. The 2 patients have been benefited by decreased postoperative pain, reduced scarring of the skin and rapid recovery. Two patients had benign mediastinal tumors; teratodermoid on anterior mediastinum and neurilemmoma on posterior mediastinum. There were no operative death and complication, median hospital stay was four days.