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Incidental Multiple Pulmonary Nodules: Benign Metastasizing Leiomyoma and $^{18}F-FDG$ PET/CT  

Lee, Seok-Mo (Department of Nuclear Medicine, Kosin University Medical School)
Publication Information
Nuclear Medicine and Molecular Imaging / v.41, no.3, 2007 , pp. 258-259 More about this Journal
Abstract
Benign metastasizing leiomyoma(BML) is a rare condition affecting women with a history of having undergone hysterectomy or myomectomy for a benign uterine fibroid, that is found to have metastasized to extrauterine sites, usually many years after hysterectomy. 1,2) Patient with BML almost always asymptomatic, although if the lesions are large enough, they can cause compressive symptoms. Among several hypothesis of pathogenesis, most plausible theory is that these tumors represent a true metastatic lesion but are very low-grade sarcoma. 3) Because the tumor is responsive to estrogen, menopause and pregnancy have slowed the growth of these lesion 4) and it seems reasonable to perform hysterectomy in patients with a uterine mass and, at the same time, perform oophorectomy for hormonal control. BML is an unusual cause of diffuse pulmonary nodules which should be considered in females with unexplained nodules and a history of surgery for uterine leiomyoma.
Keywords
multiple pulmonary nodules; benign metastasizing leiomyoma; $^{18}F-FDG$ PET/CT;
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