• Title/Summary/Keyword: behavioral activity

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Changes of M1 muscarinic receptor mRNA and $[^3H]$ pirenzepine receptor binding in the brain of sensitized mice by methamphetamine administration

  • Kim, Kyung-In;Yoo, Ji-Hoon;Cho, Jae-Han;Im, Ki-Dong;Lee, Seok-Yong;Lee, Sun-Bok;Jang, Choon-Gon
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.84.1-84.1
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    • 2003
  • Methamphetamine is a powerful stimulant that appears to produce locomotor activity and behavioral sensitization. Previous study has indicated that dopaminergic receptors are implicated in the behavioral responses of methamphetamine. Recently, it has been reported that other receptors, especially, M1 muscarinic acetylcholine receptor (M1R) plays an important role in the regulation of behavioral responses, and this receptor is abundantly expressed in brain regions, including the cerebral cortex, striatum, and the hippocampus of the animal. (omitted)

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Behavioral Characteristics of Second Graders in Science Learning Situations: A Phenomenological Research on a Motivation System about Science Learning (초등학교 2학년 학생들이 과학학습 상황에서 보이는 행동 특성: 과학학습 동기체계에 관한 현상학적 연구)

  • Lim, Sung-Man;Kang, Won-Mi;Wee, Soo-Meen;Yang, Il-Ho
    • Journal of The Korean Association For Science Education
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    • v.32 no.4
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    • pp.625-640
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    • 2012
  • The purpose of this study was to investigate the behavioral characteristics of elementary second graders depending on SL-BIS/BAS (Behavioral Inhibition/Activation System about Science Learning) in science learning situation. For this study, 20 second grade students participated. This study followed a phenomenological research method, a form of qualitative research. As the results show, students who have a sensitive motivation system to SL-BIS directly expressed their disappointment of the result and easily get distracted in class when they failed in science learning activity. They participated in group work passively, for example, they interacted less in the group or avoided answering questions. Even though the students have a lot of questions that were usually simple, empty or repetitive words. They have within themselves the good will of challenging difficult experiment that was their only expression of passive will. The students have a tendency to be dependent on their friends in an experiment, making it unlikely that they preferred group work from the beginning. Otherwise, students who have sensitive motivation system to SL-BAS endured science learning activity to the end regardless of the negative result. In particular, they were enthusiastically working on home-school materials. When the students succeeded in the experiment, they responded to the cheers and openly expressed their feeling. They were satisfied with their achievement. The students have more desire for in-depth activity. Their questions were more progressive, specific and expanded. They showed a strong desire to challenge difficult experiment and preferred to interact with their group members to help each other. Based on the results, they were limited but we could find that the behavioral characteristics of second grade students in science learning situations can be predicted with a score of SL-BIS/BAS t.

Evaluation of the Caffeine Contents in Tea and Coffee by HPLC and Effect of Caffeine on Behavior in Rats (HPLC를 이용한 차와 커피에 함유된 카페인의 함량 조사와 카페인이 흰 쥐의 행동에 미치는 영향 연구)

  • An, Jung-Hwa;Mahat, Bimit;Lee, Byung-Yo;Park, Woo-Kyu;Kwon, Kwang-Il
    • Korean Journal of Clinical Pharmacy
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    • v.22 no.2
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    • pp.167-175
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    • 2012
  • Different studies have been conducted regarding caffeine as psychostimulant drugs and its effects as well as determination in various materials. Since, coffee and tea are most drinkable beverage in the world and their major constituent is caffeine. So, analysis of the effect of equal amount of caffeine in coffee and tea with respect to SD rats was studied. The present methodology was purposed to determine and validate caffeine amount in different brands of coffee and tea, and canvass locomotor and behavioral patterns of SD rats after administrating coffee and tea orally consisting of same amount of caffeine (10, 30 mg/kg). Determination of caffeine in different brands of coffee and tea and validation of caffeine were evaluated using HPLC. Depending upon different brands of tea and coffee, caffeine amount was altered. Meanwhile, amount of caffeine in tea was directly proportional to the temperature of liquid. Coffee and tea (Instant Maxim original coffee$^{(R)}$ and earl grey black tea$^{(R)}$) consisting 10, 30 mg/kg of caffeine were studied in SD rats for locomotor activity and behavioral patterns using Tru Scan 99. The locomotor activities of SD rats were increased after administration of coffee and tea consisting caffeine compared to water. The coffee consisted of higher amount of caffeine exhibited steep movement of SD rats. Similarly, rearing and scratching of SD rats as frequency and duration were increased in coffee and tea consisting caffeine compared with water. The study revealed that coffee and tea had effects in locomotor activity and behavioral patterns of SD rats.

Factors That Affect Suicidal Attempt Risk Among Korean Elderly Adults: A Path Analysis

  • Ro, Junsoo;Park, Jongheon;Lee, Jinsuk;Jung, Hyemin
    • Journal of Preventive Medicine and Public Health
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    • v.48 no.1
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    • pp.28-37
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    • 2015
  • Objectives: Among the Korean elderly (those 65 years of age and older), the suicide rate is 80.3/100 000 people, which is ten times higher than the Organization for Economic Cooperation and Development average. Because South Korea is rapidly becoming an aging population, this high elderly suicidal rate will only get worse. Although the size of the elderly suicide problem is quite large, previous research in South Korea has surveyed restricted areas and not the entire country. Even though the factors that affect elderly suicide are complicated, there has been little research into these influencing factors. Thus, this research uses the national survey data (Community Health Survey) that was obtained in 2009. Additionally, we analyze factors affecting elderly suicidal ideation and attempts as well as the paths of these effects. Methods: Community Health Survey data obtained by the Korea Centers for Disease Control and Prevention in 2009 was used for this study. We additionally examined the factors that affect suicide with chi-squared tests, t-tests, Pearson's correlation test, and path analysis. Results: Depressive symptoms and suicidal ideation are the only factors that directly affect suicidal attempts. Demographic, behavioral, and physical activity factors have indirect effects on suicidal attempts. Conclusions: Depression has the strongest influence on suicidal ideation and attempts. Demographic, behavioral, and physical activity factors affect suicidal attempts mostly through depressive symptoms. In addition, there is a path that suggests that demographic, behavioral, and physical activity factors affect suicidal attempts not through depression symptoms but only through suicidal ideation. This means that the elderly who do not have depression symptoms attempt suicide according to their own situations and characteristics.

Functional Neuroimaging of General Fluid Intelligencein Prodigies

  • Lee, Kun-Ho
    • Proceedings of the Korean Society for the Gifted Conference
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    • 2003.05a
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    • pp.137-138
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    • 2003
  • Understanding how and why people differ is a fundamental, if distant, goal of research efforts to bridge psychological and biological levels of analysis. General fluid intelligence (gF) is a major dimension of individual differences and refers to reasoning and novel problemsolving ability. A conceptual integration of evidence from cognitive (behavioral) and anatomical studies suggeststhat gF should covary with both task performance and neural activity in specific brain systems when specific cognitive demands are present, with the neural activity mediating the relation between gF and performance. Direct investigation of this possibility will be a critical step toward a mechanistic model of human intelligence. In turn, a mechanistic model might suggest ways to enhance gF through targeted behavioral or neurobiological intervent ions, We formed two different groups as subjects based on their scholarly attainments. Each group consists of 20 volunteers(aged 16-17 years, right-handed males) from the National Gifted School and a local high school respectively. To test whether individual differences in general intelligence are mediated at a neural level, we first assessed intellectual characteristics in 40 subjects using standard intelligence tests (Raven's Advanced Progressive Matrices, Wechsler Adult Intelligence Scale, Torrance Tests of Creative Thinking) administered outside of the MR scanner. We then used functional magnetic resonance imaging (fMRl) to measure task-related brain activity as participants performed three different kinds of computerized reasoning tasks that were intended to activate the relevant neural systems. To examine the difference of neural activity according to discrepancy in general intelligence, we compared the brain activity of both extreme groups (each, n=10) of the participants based on the standard intelligence test scores. In contrast to the common expectation, there was no significant difference of brain region involved in high-g tasks between both groups. Random effect analysis exhibited that lateral prefrontal, anterior cingulate and parietal cortex are associated with gF. Despite very different task contents in the three high-g-low-g contrasts, recruitment of multiple regions is markedly similar in each case, However, on the task with high 9F correlations, the Prodigy group, (intelligence rank: >99%) showed higher task-related neural activity in several brain regions. These results suggest that the relationship between gF and brain activity should be stronger under high-g conditions than low-g conditions.

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Relationships between Children's Personality Traits and Self-Esteem in Terms of Children's Sex (아동의 성별에 따른 성격특성과 자아존중감과의 관계)

  • Park, Young-Yae;Choi, Young-Hee;Park, In-Jeon;Kim, Hyang-Eun
    • Korean Journal of Human Ecology
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    • v.12 no.3
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    • pp.275-286
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    • 2003
  • The purposes of this study were to identify the relationship between children's personality traits and self-esteem, and to find out if there were any differences in the relationship patterns in terms of children's sex. The questionnaire were collected from 984 subjects in 5th grade of elementary schools located in cities of Seoul, Suwon, Daejeon, and Daegu. Results showed that personality factors such as stability, sociability, responsibility, and superiority had stronger correlations with self-esteem factors whereas masculinity, activity level, and reflectivity did so to a less degree. Children's personality factors such as superiority, sociability and responsibility were better predictors of their self-esteem factors such as scholastic competence, social acceptance and general self-worth. Girls showed higher level of stability, sociability, responsibility and superiority, however there was no sex difference in the self-esteem such as scholastic competence, social acceptance and general self-worth. Children's behavioral conduct were mainly explained by masculinity, activity level, and responsibility. Responsibility turned out to be the strongest predictor of behavioral conduct among boys, while the activity level did among girls.

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Changes in Behavior and the Effect of Chronic-methamphetamine Following Lesions of the Nucleus Accumbens Septi in Rats (측좌핵(側坐核)(Nucleus Accumbens Septi) 파괴가 Methamphetamine의 작용에 미치는 영향)

  • Lee Soon-Chul
    • The Korean Journal of Pharmacology
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    • v.20 no.1 s.34
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    • pp.33-39
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    • 1984
  • The present study was undertaken to elucidate the chracteristics in behavioral changes of chronic doses of methamphetamine on open-field activity in rats. On the other hand, the nucleus accumbens septi(NAB), one of the major areas containing mesolimbic dopaminergic terminals, has been considered to be an important site of action for dopaminergic agonists. Therefore, it also designed to investigated influence of NAB lesions. on behavioral effects of chronic-methamphetamine. Caudal and rostral areas of NAB(cr-NAB) were lesioned by applying DC of 3.0 mA for 15 sec., simultaneously. The results were as follows: 1) The rats exhibited hyperactivity after chronic administration of methamphetamine 2) The cr-NAB-lesioned rats showed a significant increase in locomotor activity only at 2 days after NAB lesions 3) Methamphetamine-induced hyperactivity was significantly decreased in the NAB-lesioned rats, and stereotyped behavior was induced instead by the drug. 4) Dopamine content of striatum was significantly decreased and serotonin content of olfactory bulb was significantly increased in NAB-lesioned rats. These results suggest that NAB plays an important role in locomotor activity and methamphetamine-induced hyperactivity.

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Factors Influencing Depressive Symptoms in Patients with Osteoarthritis (골관절염 환자의 우울 정도와 관련요인)

  • Kim, Jung-Suk;Kim, Chun-Ja
    • Journal of muscle and joint health
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    • v.27 no.2
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    • pp.199-209
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    • 2020
  • Purpose: This study examined the prevalence of depressive symptoms and psycho-behavioral factors affecting depressive symptoms in patients with osteoarthritis. Methods: This cross-sectional study enrolled a convenience sample of 157 patients with osteoarthritis in a university hospital between March and December 2018. Depressive symptoms, osteoarthritis function, therapeutic self-efficacy, and health-related quality of life (QoL) were measured using structured questionnaires. Logistic regression analysis was used to investigate factors affecting depressive symptoms. Results: The mean age of participants was 73.3 years with 76.4% of them being women. The prevalence of depressive symptoms was 38.5%. Patients with depressive symptoms were more likely to be currently smoking and had an occupation and worse flexibility function associated with osteoarthritis. Whereas they were less likely to engage in regular physical activity and had a low level of therapeutic self-efficacy and perceived health-related QoL. Conclusion: Therapeutic self-efficacy to regular physical activity, including flexibility function may be primary factors influencing depressive symptoms in patients with osteoarthritis. With the management of osteoarthritis, psycho-behavioral factors should be considered in developing interventions to prevent depressive symptoms in patients with osteoarthritis.

Analysis of the Types of Dementia Patients for Development of Clothes for Dementia Patient in Nursing Homes (요양시설 치매환자복 디자인 개발을 위한 치매환자의 유형 분석)

  • Park, Kwang Ae;Yang, Chung Eun;Lee, Jae Hyang;Kim, Hee-Jung
    • Journal of the Korean Society of Clothing and Textiles
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    • v.45 no.5
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    • pp.788-803
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    • 2021
  • This study aims to obtain basic data to develop clothes for dementia patients by classifying types of dementia patients. Data was collected from those dementia patients who entered a nursing home. This study analyzed a total of 221 sheets. Furthermore, descriptive statistics, cross-tabulation, and K-means clustering were performed for statistical processing using Minitab 14. As a result, dementia patients were classified into four types: inactive-dependent, active-problematic behavior, activity-autonomy, and inactive-offensive. Inactive-dependent type was a group with the most severe disability in cognitive and daily activity functions; however, they lacked behavioral and psychological symptoms and problematic behavior with clothes. Active-problematic behavior type showed the most behavioral and psychological problems and problematic behavior with clothes. Activity-autonomy type was a group without any problematic behaviors. Moreover, the inactive-offensive type had very good cognitive function toward humans. The study imply that it is necessary to provide clothes with proper functions based on the types of patients rather than providing them uniform clothes because clinical and clothes behaviors differ significantly depending on the types of dementia patients.

Insecticidal Activity and Behavioral Disorders by Pyrifluquinazon to Trialeurodes vaporariorum and Bemisia tabaci (온실가루이와 담배가루이에 대한 pyrifluquinazon의 살충 및 행동장애)

  • Lee, Seon-Woo;Song, Myung-Kyu;Ahn, Ki-Su;Kim, Young-Jae;Moon, Yil-Sung;Koo, Hyun-Na;Kim, Gil-Hah
    • The Korean Journal of Pesticide Science
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    • v.17 no.1
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    • pp.33-40
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    • 2013
  • Pyrifluquinazon is known to act as a feeding inhibitor in several insect species. In this study, we investigated the effect of pyrifluquinazon on the whiteflies, Trialeurodes vaporariorum and Bemisia tabaci. Pyrifluquinazon showed high insecticidal activity (> 90%) against adult T. vaporariorum and B. tabaci at 12.5 ppm to 50 ppm. However, there was no effect on eggs and nymphs of both species. Pyrifluquinazon showed low insecticidal activity in root and foliar uptake. Control efficacy of pyrifluquinazon was above 90% at 5 days after treatment. In order to investigate the behavioral response of the whiteflies initiated by application of pyrifluquinazon, we tested the contact toxicity and ingestion toxicity. After 1 h of contact, whitefly drop, wing convulsion, and paralysis were observed. Similar phenomenon of whitefly population was observed in test of ingestion toxicity after 3 h. In the choice test, pyrifluquinazon showed repellent activity against both species. These results suggest that pyrifluquinazon cause behavioral disorder rather than direct inhibition of feeding.