• Macromolecular Research
• /
• v.16 no.4
• /
• pp.293-302
• /
• 2008

In our previous publication, the problem of particle deformation and coagulation at the nucleation stage in the presence of cross-linker was intensely studied by seeded batch dispersion polymerization of methyl methacrylate (MMA). In the present work, highly cross-linked, monodisperse PMMA particles were prepared under various reaction conditions by seeded semi-continuous process. Monodisperse, $6.5{\mu}m$-diameter PMMA particles containing up to 8 wt% of DVB or EGDMA were successfully made by seeded semi-continuous process and multi-semi-continuous addition process, respectively. Therefore, this study shows that seeded semi-continuous process is more effective and efficient to prepare highly cross-linked, monodisperse particles than non-seeded and seeded batch processes.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.7 no.6
• /
• pp.371-374
• /
• 2002

Production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate)［P(3HB/V)］, by fed-batch culture of recombinant Escherichia coli harboring a plasmid containing the Alcaligenes latus polyhy-droxyalkanoate (PHA) biosynthesis genes, was examined in two pilot-scale fermentors with air supply only, In a 30 L fermentor having a XLa value of 0.11 S­$^1$, the final P(3HB/V) concentration and the P(3HB/V) content obtained were 29.6 g/L and 70.1 wt%, respectively giving a productivity of 1.37 g P(3HB/V)/L-h. In a 300 L fermentor having a XLa of 0.03 S­$^1$, the P(3HB/V) concentration and the P(3HB/V) content were 20.4 g/L and 69 wt%, respectively giving a productivity of 1.06g P(3HB/V)/L-h. These results suggest that economical production of P(3HB/V) is possible by fed-batch culture of recombinant E. coli in a large-scale fermentor having low KLa value.

• Korean Chemical Engineering Research
• /
• v.46 no.2
• /
• pp.316-329
• /
• 2008

Recently the increased attention pays on the processing of multiple, relatively low quantity, high value-added products resulted in adoption of batch process in the chemical process industry such as pharmaceuticals, polymers, bio-chemicals and foods. As there are more possibilities of the improvement of operations in batch process than continuous processes, a lot of effort has been made to enhance the productivity and operability of batch processes. But the chemical process industry faces a range of uncertainties factors such as demands for products, prices of product, lead time for the supply of raw materials and in the production, and the distribution of product. And global competition has made it imperative for the process industries to manage their supply chains optimally. Supply chain management aims to integrate plants with their supplier and customers so that they can be managed as a single entity and coordinate all input/output flows (of materials, information) so that products are produced and distributed in the right quantities, to the right locations, and at the right time.The objective of this study is to solve the purchase, distribution, production planning and scheduling problem, which minimizes the total costs of production, inventory, and transportation under uncertainty. And development of SCM model in chemical industry including batch mode operations. Through that, the enterprise can respond to uncertainty. Also integrated process optimal planning and scheduling model for manufacturing supply chain. The result shows that, the advantage of supply chain integration are quality matters seen by customers and suppliers, order schedules, flexibility, cost reduction, and increase in sales and profits. Also, an integration of supply chain (production and distribution system) generates significant savings by trading off the costs associated with the whole, rather than minimizing supply chain costs separately.

• Biotechnology and Bioprocess Engineering:BBE
• /
• v.7 no.4
• /
• pp.254-254
• /
• 2002

A process for the production of mannitol from fructose (5% to 25%) using Leuconosyoc mesenteroides NRRL B-1149 was investigated. Fermentations were carried out in bat도 of fed-batch fermentations without aeration at 28℃, pH 5.0. When 5% fructose was used in batch culture fermentation, the yield of mannitol was 78% of that expected theoretically. When the fructose concentration was increased to 10%, the yield dropped to 59.6% of the theoretical value. However, in the fed-batch culture, using 10% fructose, the yield was 81.9% of the theoretical value. In a 15% fructose fed-bat도 culture, with 5% fructose being added initially and the other 10% fructose being added as a continuous supply, the final yield was 83.7% of the theoretical yield. When 20% fructose was used in the same manner, the yield was 89.5% of theoretical yield.

• KSBB Journal
• /
• v.15 no.4
• /
• pp.380-387
• /
• 2000

An extractive fermentation process using pervaporation was studied in a 7 liter fermentor. Pervaporation was performed using a silicone membrane module and a low-acid-producing strain Clostridium acetobutylicu, B18 was used to produce butanol. In batch culture without pervaporation pH 5.5 and initial glucose concentration of 60 g/L resulted in the highest butanol productivity (0.216 g/L$.$h) with butanol yield of 0.261 Butanol flux through the membrane was best at 2.0 L/min-tubing of air flow rate In batch and fed-batch fermentation glucose consumption rate increased by 1.3 times with pervaporation.

• Journal of the Korean Society of Visualization
• /
• v.13 no.3
• /
• pp.24-28
• /
• 2015

The temperature of the wafer batch in the furnace was calculated and its visualized temperature field was analyzed. The main heat transfer mechanisms from the heater wall to the wafers were radiation and conduction, and the finite difference method was used to analyze the complex heat transfer including those two mechanisms. The visualized temperature field shows that the direction of the heat flux in the wafer batch varies during the heating process, and the heat in the wafer batch diffuses faster by conduction within the wafer than by radiation between the wafers, in the condition of the constant temperature at the heater wall and cap.

• Journal of Korean Society of Water and Wastewater
• /
• v.8 no.3
• /
• pp.1-8
• /
• 1994

In the general process of design for aerobic digestion, the design for field plant of which inflow pattern is continuous inflow is performed using the results from lab scale batch reactor. However, the recent researchers reported that the general designs were performed as over-estimated, Therefore, in this study, laboratory batch experiments were carried out at $20^{\circ}C$ and pH 7.5 on the aerobic digestion of waste activated sludge at different solid levels. This treatise could consider the negligence about effective digestion periods the usage of VSS as solid concentration, and the effect of initial solid concentration of solid degration rate coefficient($k_d$) as reasons of the overestimated design, and showed the scheme of how to design for aerobic digestion from batch experiment.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.11
• /
• pp.4726-4731
• /
• 2011

This paper proposed the algorithm to select optimal grinding condition for plunge grinding in the batch production unit. In order to apply to the proposed algorithm, the state variable for plunge grinding process was defined and the optimal grinding condition for each cycle in batch production was decided by genetic algorithm. Based on the optimized grinding condition in each cycle, the optimal grinding condition for whole batch production was selected by dynamic programming. The proposed algorithm was evaluated by computer simulation.

• Macromolecular Research
• /
• v.15 no.3
• /
• pp.244-255
• /
• 2007

Nucleation is the most sensitive stage in the preparation of highly cross-linked, monodisperse microspheres by dispersion polymerization, since the addition of a small amount of cross-linker results in particle deformation and coagulation. To overcome these problems, $5\;{\mu}m$ poly(methyl methacrylate) seed particles prepared by dispersion polymerization were used in the preparation of mono disperse, cross-linked PMMA particles containing up to 7 wt% divinylbenzene by seeded batch dispersion polymerization. Spherical particles with a narrow size distribution containing up to 8 wt% of EGDMA were prepared by seeded multi-batch dispersion polymerization processes. These particles were identified by scanning electron microscopy and DSC.

• Environmental Engineering Research
• /
• v.16 no.2
• /
• pp.97-102
• /
• 2011

This study investigates the treatment of pigment wastewater using a sequential batch reactor (SBR) followed by dissolved ozone flotation-pressurized ozone oxidation treatement (DOF-$PO_2$). The process efficiency has been evaluated at the lab scale on the basis of water quality parameters. In addition, the effect of pure oxygen and air was investigated on the removal of COD, BOD, and TN in the SBR process. It was observed that under comparable conditions the removal efficiencies of these water quality parameters using pure oxygen and air were similar. The effect of the recycle rate was also investigated for its impact on the water quality parameters using different ozone dissolving pressures in a DOF process in order to optimise conditions. The results conclude that the use of an SBR and ozone contact by DOF-$PO_2$ is a highly effective treatment for pigment wastewater and aids in the achievement of effluent discharge criteria.