• 대한약침학회지
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• 제20권1호
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• pp.10-17
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• 2017

Objectives: Boswellic acid (BA), a compound isolated from the gum-resin of Boswellia carterii, is a pentacyclic terpenoid that is active against many inflammatory diseases, including cancer, arthritis, chronic colitis, ulcerative colitis, Crohn's disease, and memory impairment, but the mechanism is poorly understood. This study investigated the effects of boswellic acid on spatial learning and memory impairment induced by trimethyltin (TMT) in Wistar rats. Methods: Forty male Wistar rats were randomly divided into 5 groups: Normal group, TMT-administrated rats (8.0 mg/kg, Intraperitoneally, i.p.) and TMT + BA (40, 80 and 160 mg/kg, i.p.)-administrated rats. BA was used daily for 21 days. To evaluate the cognitive improving of BA, we performed the Morris water maze test. Moreover, to investigate the neuroprotective effect of BA, we determined the acetylcholinesterase (AchE) activity, the malondialdehyde (MDA) level as a marker of lipid peroxidation, and the glutathione (GSH) content in the cerebral cortex. Results: Treatment with TMT impaired learning and memory, and treatment with BA at a dose of 160 mg/kg produced a significant improvement in learning and memory abilities in the water maze tasks. Consistent with behavioral data, the activity of AChE was significantly increased in the TMT-injected rats compared to the control group (P < 0.01) whereas all groups treated with BA presented a more significant inhibitory effect against AChE than the TMT-injected animals. In addition, TMT reduced the GSH content and increased the MDA level in the cerebral cortex as compared to the control group) P < 0.01). On the other hand, treatment with BA at 160 mg/kg slightly increased the GSH content and reduced the MDA level in comparison to the TMT-administered group (P < 0.01). Conclusion: The above results suggest that the effect of BA in improving the cognitive function may be mediated through its antioxidant activity.

• 한국초등과학교육학회지:초등과학교육
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• 제26권5호
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• pp.499-508
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• 2007

본 연구의 목적은 외국 교육과정에 나타난 분류, 예상 및 추리 탐구 요소를 살펴보고, 우리나라 3학년부터 10학년까지의 과학교과서에 나타난 기초 탐구 과정 중에서 분류, 예상 및 추리가 어떻게 제시되어 있는지 알아보는 것이다. 분석 결과는 다음과 같다. 분류에서는 전체 빈도수가 관찰이나 측정에 비해서 적었으며, 초등학교에서 많이 발견되었다. 분류의 단계는 '한 가지 특성에 의한 분류'가 대부분이고 분류의 상위 단계인 '복합 특성 특성에 따른 분류' 활동은 많이 발견되지 않았다. 예상에서는 대부분이 실험 결과를 이용한 예상 활동이었고, 예상의 단계에서 초보적 예상이 대부분으로 예상의 상위 단계인 조작적 예상은 많이 발견하지 못했다. 추리는 분류와 예상에 비해서 많은 빈도수를 나타냈으며, 학년급간 분포에서도 상위 학년에서 많은 빈도수를 나타내었다. 또한, 추리의 단계에서도 초등학교에서 중고등학교로 넘어가면서 추리의 상위단계인 이차적 추리의 빈도가 증가하였다.

• 토지주택연구
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• 제2권4호
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• pp.379-385
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• 2011

국내의 건물부문 에너지 소비량은 전체 소비량의 약 25%를 차지하고 있으며, 생활수준의 향상, 세대수의 증가 등에 기인하여 선진국 수준으로 지속적인 증가추세를 보일 것으로 전문가들은 예측하고 있다. 한편 정부는 2009년부터 녹색뉴딜사업의 일환으로 국토 에너지 수자원 건물 등의 각종 기본정보를 체계적으로 일원화시키고 통합 DB를 구축하는 녹색국가 정보인프라 사업을 추진 중에 있다. 특히 건물과 관련해서는 에너지 절약과 온실가스 저감 대책 마련에 효율적으로 대응하기 위한 수단으로, 건물단위의 에너지 소비량 관리를 기본 골자로 하는 건물 에너지 통합관리시스템 구축을 강구중에 있다. 본 연구에서는 국가 건물에너지 통합관리시스템 구축(이하, 통합관리시스템)에 요구되는 추진계획 및 로드 맵 작성을 목적으로, 기존 에너지 소비량 관련 자료 조사 및 전문가 면담 등의 분석을 통하여 통합관리시스템의 목표와 계획 수립에 따른 단계별 전략과제와 핵심과제를 도출하고자 한다. 나아가, 건물부문의 에너지 및 온실가스 통계 마련과 관리를 위한 통합관리센터의 구축과 운영방안 수립에 활용할 수 있는 방안을 제시하여 향후 녹색뉴딜 사업의 육성을 도모하고자 한다.

• 한국컴퓨터정보학회논문지
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• 제24권6호
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• pp.37-43
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• 2019

This study focused on the design and development of contents using Unplugged CS method to learn computer science knowledge. With the strengthening of software education, all universities students including elementary and junior high school students are demanding knowledge of computer science centered on the computational thinking. We have developed educational contents using unplugged computing method as a way to effectively learn the concept of computer science. First, we analyze the related research of Unplugged CS theory and investigate the educational method accordingly. And we divided the areas of computer science and selected learning concepts in each area. The contents of learning were divided into basic and intermediate classes considering the level of the learner. The subject of learning contents was selected evenly in the area of computer science and it consisted of 16 basic subjects and 16 intermediate subjects based on concepts that are important in each field. In order to confirm the validity of the Unplugged CS learning topic and the development contents for computer science, we conducted expert reviews and content validity tests. As a result of the validity test, the validity of the learning topic and area selection was found to be more than .92 for the CVI value and the validity of the 32 subject learning contents was over .935 in basic level and .925 in intermediate level for the CVI values. Based on the design contents, we developed digital contents for online learning and put them in the system. We expect that this study will contribute to the understanding of computer science for all, including elementary and junior-high school students as well as students at software - oriented universities, and contribute to the spread of software education.

• 대한건축학회논문집:구조계
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• 제34권2호
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• pp.29-40
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• 2018

Strength design wind loads for the wind resistance design of structures shall be evaluated by the product of wind loads calculated based on the basic wind speed with 100 years return period and the wind load factor 1.3 specified in the provisions of load combinations in Korean Building Code (KBC) 2016. It may be sure that the wind load factor 1.3 in KBC(2016) had not been determined by probabilistic method or empirical method using meteorological wind speed data in Korea. In this paper, wind load factors were evaluated by probabilistic method and empirical method. The annual maximum 10 minutes mean wind speed data at 69 meteorological stations during past 40 years from 1973 to 2012 were selected for this evaluation. From the comparison of the results of those two method, it can be found that the mean values of wind load factors calculated both probability based method and empirical based method were similar at all meteorological stations. When target level of reliability index is set up 2.5, the mean value of wind load factors for all regions should be presented about 1.35. When target level of reliability index is set up 3.0, wind load factor should be presented about 1.46. By using the relationship between importance factor(conversion factor for return period) and wind load factor, the return periods for strength design were estimated and expected wind speeds of all regions accounting for strength design were proposed. It can be found that return period to estimate wind loads for strength design should be 500 years and 800 years in according to target level of reliability index 2.5 and 3.0, respectively. The 500 years basic wind speed map for strength design was suggested and it can be used with a wind load factor 1.0.

• 한국수학교육학회지시리즈E:수학교육논문집
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• 제24권3호
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• pp.525-541
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• 2010

P대학에서는 교양수학 교과에 대한 기초학력 부진학생들의 문제해결력 향상을 위하여, 대학 교육역량강화사업의 일환으로 수학카페 운영과 함께, 기초수학 특강, 개인지도 및 컴퓨터 활용학습 등을 시행하고 있다. 본 논문에서는 여름 및 겨울방학을 이용하여 기초수학 특강을 실시하고, 그 결과를 중심으로 수학에 대한 기초학력 부진학생들을 위한 효율적인 기초수학 학습지도 방안을 살펴보고자 한다.

• 실천공학교육논문지
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• 제10권2호
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• pp.95-102
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• 2018

대학 공학계열 신입생들 중 많은 학생들이 기초학력 저하로 전공과목 수강에 어려움을 겪고 있으며 이는 대학 수준에 관계 없이 전국의 모든 대학에서 나타나는 현실이기도 하다. 이러한 학습부진과 기초학력 저하를 해결하기 위하여 본 연구에서는 A대학에서 기계공학을 전공하려는 학생들 중 기초역학에 대한 학습능력이 부족한 학생들을 대상으로 기초학력강화 프로그램을 운영하고 사전 및 사후 검사 결과를 통하여 그 실효성을 확인하고 설문조사를 통하여 만족도를 조사하였다. 사전 사후 검사 결과 A집단에서는 평균 40.1% 향상되었으며 B집단에서는 평균 18.9% 향상된 것으로 조사되었다. 프로그램 이수 후 실시한 만족도 조사 및 심층 면담 결과 기초학력강화 프로그램은 전체 평균 90.6%(4.53/5.0)의 높은 만족도를 나타내어 전공 과목에 대한 흥미와 학업에 대한 자신감을 높이는데 기여 했을 뿐 아니라 교수와 참여 학생과의 긍정적인 관계 형성에 큰 도움을 준 유용한 프로그램임을 확인하였다.

• 한국약용작물학회지
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• 제21권3호
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• pp.165-173
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• 2013

The fruits of Schisandra chinensis have been used as an edible ingredient and traditional medicine in Korea. Due to morphological similarities of dried mature fruits, the correct identification of S. chinensis from other closely related Schisandrae species is very difficult. Therefore, molecular biological tools based on genetic analysis are required to identify authentic Schisandrae Fructus. Random amplifed polymorphic DNA (RAPD) and Sequence Characterized Amplified Region (SCAR) were used to develop an easy, reliable and reproducible method for the authentication of these four species. In this paper, we developed several RAPD-derived species specific SCAR markers and established a multiplex-PCR condition suitable to discriminate each species. These genetic markers will be useful to distinguish and authenticate Schisandrae Fructus and four medicinal plants, S. chinensis, S. sphenanthera, S. repanda and K. japonica, in species level.

• Journal of Microbiology
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• 제40권3호
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• pp.230-233
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• 2002

Effects of short-chain primary amines on Aspergillus nidulans development were analyzed. Propylamine induced asexual development and inhibited sexual development. Even on medium containing lactose as the sole carbon source, on which little conidial heads are formed and sexual structures are formed preferentially, or when sexual development was induced, propylamine induced asexual development and inhibited sexual development. These effects of propylamine seemed to be due to accumulation of mRNA of the brlA gene, which has been identified as a positive regulator of asexual development, and due to the reduction of the veA mRNA level. The veA gene has been identified as an activator of sexual development and also as an inhibitor of asexual development. Other primary amines, methylamine and ethylamine, showed identical effects on development where short-chain primary amino also promoted asexual development and inhibited sexual development.

• 부모자녀건강학회지
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• 제6권1호
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• pp.1-17
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• 2003

Thus, I studied Health services supplied by local health centers and the requirements of the inhabitants visiting the health care facilities. The purpose of this study was to provide basic material for the establishment of Health care policy and the development of health care businesses. The target places for this study were 4 health centers; Chungrang-Gu, Nowon-Gu, Eunpyung-Gu, Songpa-Gu, with 509 mothers who were visiting the Centers. The question items of this study concerned a total of 124 health-related services provided by the Health Centers. The data was collected for a total of 92 days; July 1st~September 30th, 1999. 800 questionaries were distributed and 559 answered, 509 were analyzed finally. The collected data were processed using the SAS program to get mean, standard deviation, percentage. Open questions were made to reveal the opinions of mothers using the health care center. The results were as follows : 1. Among the participants of the study, 49.7% were 25~29 years of age, 84.3% were house wives by current occupation, 56.2% were from 4~6 person households. 52.1 were educated at a high school level, and 43.6% were educated at a collage level. 2. The highest percentage(53.6%) of the users were spontaneous in their utilization of health care center. The major reason for using the Health care center is that it is free to 65.8% of those covered and of low cost to 19.3% of those covered. 3. The satisfaction level of those using the health care center appeared to be generally high. The general average value showed up as $3.027{\pm}0.519$. 4. The level of recognition of the value of the heath care center services was high, particularly in the basic item of diagnoses of pregnancy, particularly in the basic item of diagnoses of pregnancy. However, the satisfaction level of health care education In pregnancy is low at 20~40%. In the meantime, the level of recognition in breast- feeding benefits is high at 76.8%. 5. The rate of realizing health care center's service campaign was generally low at 10~20%. 41.3 of the people knew the advertizing material of the health care centers. 32.4% of the people knew the advertizing material of the health care centers. 32.4% of the people knew the campaign of health care center for importance of breast-feeding benefits. 30.1% of the people knew the campaign for testing congenital mechanism disease. In the meantime about 50% was recognised the health care centers campaign for the importance and time of infants vaccination. 6. The need for enhancement of health care center services was shown to be high as $3.266{\pm}0.676$ as an average, chicken pox vaccination being the most highly requested at $3.565{\pm}0.587.$. 7. Among the open questions, the additional service to be provided were as follows ; increase of campaign of health care center services, furnishing advertizing books in public locations, providing shuttle bus service to the health care centers, extension of desire for preventative injections, rest and play areas for the children of the families serviced, consultation rooms, etc.