• 제목/요약/키워드: bases

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Comparative evaluation of sodium hypochlorite and microwave disinfection on dimensional stability of denture bases

  • Nirale, Rutuja Madhukarrao;Thombre, Ram;Kubasad, Girish
    • The Journal of Advanced Prosthodontics
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    • 제4권1호
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    • pp.24-29
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    • 2012
  • PURPOSE. To compare the effect of sodium hypochlorite and microwave disinfection on the dimensional stability of denture bases without and with relining. MATERIALS AND METHODS. A brass die was prepared by simulating an edentulous maxillary arch. It was used to fabricate 1.5 mm and 3 mm of thickness denture bases (n = 40). The 1.5 mm of thickness-specimens (n = 20) were relined with 1.5 mm of autopolymerizing relining resin. Five holes were prepared over crest of ridge of brass die with intimately fitting stainless steel pins which were transferred to the intaglio surface of specimens during fabrication of denture bases. For calculation of dimensional changes in denture bases, differences between the baseline area before and after disinfection of the specimens were used. The denture bases without and with relining were divided into 2 groups (each n =20). Data were analyzed using student paired 't'and unpaired 't'test. RESULTS. Microwave disinfection produces significant shrinkage in both denture bases without relining (t =17.16; P<.001) and with relining (t = 14.9; P<.001). Denture bases without relining showed more shrinkage when compared with relined denture bases after microwave disinfection (t = 6.09; P<.001). The changes in dimensional stability after sodium hypochlorite disinfection were not significant for both denture bases without relining (t = 2.19; P=.056) and denture bases with relining (t = 2.17; P=.058). CONCLUSION. Microwave disinfection leads to increased shrinkage of denture bases without and with relining. Chemical disinfection with sodium hypochlorite seems to be a safer method of disinfection with regards to physical properties such as changes in dimensional stability.

Thalictrum uchiyamai Nakai의 항균작용에 관한 연구 (Study on the Antimicrobial Activity of Thalictrum uchiyamai Nakai)

  • 이인란;이지영
    • 약학회지
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    • 제25권4호
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    • pp.199-204
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    • 1981
  • The methanol extract of Thalictrum uchiyamai Nakai was fractionatedi nto four parts; (1) ether soluble nonphenolic fraction (2) phenolic tertiary bases fraction, (3) chloroform soluble tertiary bases fraction and (4) aqueous quaternary bases fraction. The fractions of this plant showed a total of twenty-four spots on the silica gel TLC. Ether soluble nonphenolic fraction and ether soluble phenolic fraction showed nine alkaloid spots respectively, chloroform soluble fraction showed three alkaloid spots and quaternary bases fraction showed three alkaloid spots. The antimicrobial activity of the four extracts was shown as follows; nonphenolic tertiary bases inhibited the growth of Micrococcus dutica at the concentration of $50\mu$g/ml, in phenolic tertiary bases $500\mu$g/ml concentration was inhibitory to Micrococcus dutica and to Staphyloccus aureus. In aqueous quaternary bases, $500\mu$g/ml concentration was inhibitory to Klebsiella pneumonae. Chloroform soluble tertiary fraction showed slight activity. All of bases showed reproducible activity against tested microorganisms.

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9 장용피기제에 관한 연구(제1보) Invitro Test에 의한 기제의 선택에 대하여 (Studies on Enteric Coating Bases. I Selection of Enteric Coating Bases by Invitro Test)

  • 김수억;지달현;문정현;이금정
    • 약학회지
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    • 제5권1호
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    • pp.31-36
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    • 1960
  • The importance of enteric coating technique among the pharmaceutical firms has recently risen very significantly. This study of enteric coating bases was made in order to determine the most suitable bases and dusting powders. Materials and equipment used in this experiment are shown in table 1 and kinds of enteric coating bases and their formulas are shown in table 2. The evaluation of the suitability for enteric coating bases and dusting powder was made by disintergration test after measuring the thickness of the enteric coated layer as shown in the tables 4 and 5. Based on the results of this study, the base D(shellac 20 Gm, anhydrous lanoline 5 Gm, 96% alcohol 75 ml) and the base E (shellac 10 Gm, cetyl alcohol 10 Gm. acetone 80 ml) are selected among the 8 kinds of bases studied in a preliminary test and it was found that Mg-stearate and CA-stearate were in most suitable dusting powders among the 6 kinds studied for the bases D and E. Further study on base D and E was carried out by varying the proportions of the materials which were the original constituents of bases D and E. According to the result of this further study shown in table 6, the shellac 15 Gm cetyl alcohol 5 Gm Acetone 80 ml of base E is recommended as the most suitable dusting powder.

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아스코르빈산 디팔미테이트의 경피흡수에 미치는 연고기제의 영향 (Percutaneous Absorption of Ascorbic acid Dipalmitate in Various Ointment Bases)

  • 문용구;이완하
    • Journal of Pharmaceutical Investigation
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    • 제21권2호
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    • pp.97-101
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    • 1991
  • Six different O/W cream bases containing 4% ascorbic acid dipalmitate and two different O/W cream bases containing 1% ascorbic acid were prepared. Percutanceous absorption of ascorbic acid as well as safety were determined using rabbits. The stability of the creams was also tested at room temperature. Ascorbic acid concentrations in urines varied depending on the characteristics of cream bases used. The absorption of ascorbic acid was increased and sustained with the cream bases containing branched chain esters of fatty acid instead of natural oils used currently. The excretion level of ascorbic acid in urine was high with the cream base including nonionic surfactants and a small quantity of natural oils. The creams containing nonionic surfactants showed excellent stability, while those containing anionic surfactants were not stable in terms of pH, odor and coloring test at room temperature during six months. But, the two creams containing ascorbic acid were unstable. All the cream bases tested showed good safety.

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원전 생애주기간 설계기준 정보관리를 위한 요건 분류체계 개발 (Development of Requirement Taxonomy for Design Bases Management during NPP lifecycle)

  • 김종명
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2018년도 추계 학술논문 발표대회
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    • pp.134-135
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    • 2018
  • Nuclear Power Plant consists of about 1.4 million facilities. and the design standards and design requirements for the continuos utilization and safety of facilities are complexly connected with the facilities. When a design change for facilities or design requirements is occurred at the time of construction or operation, there are a lot of facilities, design requirements, and design bases that are affected by the facilities or design bases being changed. The above design changes are so complex that the existing document-bases design change process is time-consuming and may also cause human error. In this study, we developed a design requirement taxonomy that can be applied to the data-centric design bases document that can improve it. To do this, we analyze the design elements from the highest level to the lowest level applied to the nuclear power plant, and classify the design elements according to the characteristics of the design elements.

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좌제기제가 아스피린 좌제의 생체내이용율에 미치는 영향 (Effects of Suppository Bases on Bioavailability of Aspirin Suppositories)

  • 김용현;이진환;최준식
    • Journal of Pharmaceutical Investigation
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    • 제18권2호
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    • pp.61-67
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    • 1988
  • The influence of different suppository bases on the dissolution, and the bioavailability of aspirin suppositories in rabbits and humans was investigated using Witepsol H15 (WIT), WIT-Tween 80 (TWE), WIT-sodium lauryl sulfate (SLS), polyethylene glycol (PEG), hollow WIT (WIT-HOLL) and capsule incorporated into WIT (WIT-CAP). The results obtained were as follows: 1) Dissolution rates of aspirin suppositories with different bases in distilled water were faster in the order of WIT-TWE >WIT-SLS >PEG >WIT-HOLL >WIT >WIT-CAP. 2) The maximum blood levels $(C_{max})$ of aspirin in rabbits and humans were highest in WIT-TWE and WIT-SLS bases, but $C_{max}$ from WIT base was lower than that in oral administration of aspirin suspension. 3) The times reaching the maximum blood levels $(T_{max})$ in rabbits were 1 hr for oral administration, 1.5-2.5 hr for WIT-TWE, WIT-SLS, PEG, and WIT bases, and 2.5-4.0 hr for WIT-HOLL and WIT-CAP bases, but $T_{max}$ in humans were 1 hr for oral administration and WIT-TWE base, and 2-4 hr for WIT and WIT-HOLL bases. 4) Relative bioavailability (RBA) of aspirin suppositories in rabbits was higher in WIT-SLS, WIT-TWE and PEG bases than that in oral administration, and RBA of aspirin suppositories in humans was higher in the order of WIT-TWE >PEG >WIT-HOLL >oral >WIT bases tested. 5) Good correlation between dissolution rates and $C_{max}$ was obtained: y = 0.60x+32.23 (r = 0.96) for rabbits, and y = 0.60x+35.74 (r = 0.97) for humans.

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A comparative study on the accuracies of resin denture bases and metal denture bases

  • Park Hwee-Woong;Kim Chang-Whe;Kim Yung-Soo
    • 대한치과보철학회지
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    • 제39권3호
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    • pp.250-259
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    • 2001
  • Since the late 1930s, acrylic resins have been the materials of choice for the fabrication of complete denture bases. It has excellent esthetic properties, adequate strength, low water sorption, and low solubility. But acrylic resin has disadvantage of processing shrinkage that reduces denture retention and accuracy of denture occlusion. Metals also have been used in denture base material. Metals used in denture bases display excellent strength and dimensional stability. The major disadvantages associated with metal denture bases include increased cost, difficulty in fabrication, compromised esthetic qualities, and inability to re-base. The purpose of this study is to compare the artificial tooth movements of complete dentures with resin bases and metal bases after curing, deflasking, polishing immersion in water for 1 week and 4 weeks. Twenty-four maxillary complete resin denture bases with artificial teeth were fabricated. Twelve of them were resin based and other twelve of them were metal based. Fine crosses were marked on the incisal edges of right central incisors and distobuccal cusps of be second molars. Measurements were done for the changes of distances of reference points at the time of wax denture, after deflasking after decasting after polishing after immersion in water for 1 week and 4 weeks Meaurements were done to the accuracy of 0.001mm with a measuring microscope. The results were as follows : 1. Metal base showed significantly less tooth movement than resin base after curing and decasting (p<0.01). 2. Metal base showed significantly less tooth movement than resin base after polishing (p<0.01). 3. After immersion in water for 1 week and 4 weeks, metal base showed less movement than resin base. Difference was significant for anterior-posterior distances (p<0.01), but not significant for molar-to-molar distance (p>0.01). 4. 1 week and 4 weeks of immersion failed to compensate the initial processing shrinkage of metal and resin bases (p>0.01).

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BIM기반 Algorithm을 활용한 APR1400 설계기준 통합관리 체계 구축 (Establishment of Integrated Design Bases Management System of APR1400 Using BIM based Algorithm)

  • 신재섭;최재필
    • 한국건설관리학회논문집
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    • 제20권5호
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    • pp.52-60
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    • 2019
  • APR1400은 1992년 12월부터 2001년 12월까지 약 10여년에 걸쳐 국가선도 기술개발과제를 통해 개발된 1,400MWe급 차세대 원자력발전소 노형으로, 건설을 위해서 약 6만 5천 장의 도면이 생산된다. 또한 수많은 도면 간 일치성 유지를 설계기준(Design Bases)에 따라 가장 높은 수준의 설계기준도면(Design Bases Drawing)를 작성하여 후속설계에 가이드라인 역할로 활용하고 있다. 하지만 설계기준도면이 문서기반으로 생산 관리되고 있고, 다양한 분야에서 파편적으로 운영되어 설계기준정보를 정확하게 인지하고 후속설계에 정확하게 반영하는데 어려움이 있었다. 따라서 본 연구는 문서기반의 설계기준도면의 한계를 인식하고, BIM 기반의 설계기준 통합관리 체계를 도입하여, 설계기준 정보를 체계적이고 정확하게 후속설계에 반영 할 수 있는 체계를 구축하였다. 특히 DBIL(설계기준정보층)개념을 도입하여 5가지 설계기준(물리적방호, 화재방호, 내부비산물방호, 내부침수방호, 방사선방호)을 적용하여 DBIL생성 및 속성을 분석하였다. 최종 결과물인 DBIL set와 Datasheet에는 실(Room), DBIL, 설계기준 속성, 빌딩 데이터(벽 바닥 슬라브, 문 창문, 수직 수평관통부)를 통합 추출하여 후속설계 자동화 및 설계검증에 활용할 수 있도록 하였다. 더 나아가 APR1400 DBIL에 적용되는 5가지 설계기준의 속성을 분석하여 후속호기 및 차세대 노형과의 비교를 통한 경제성 분석 등에 폭 넓게 활용할 수 있을 것이라 예상한다.

GROBNER-SHIRSHOV BASES FOR REPRESENTATION THEORY

  • Kang, Seok-Jin;Lee, Kyu-Hwan
    • 대한수학회지
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    • 제37권1호
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    • pp.55-72
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    • 2000
  • In this paper, we develop the Grobner-Shirshov basis theory for the representations of associative algebras by introducing the notion of Grobner-Shirshov pairs. Our result can be applied to solve the reduction problem in representation theory and to construct monomial bases of representations of associative algebras. As an illustration, we give an explicit construction of Grobner-Shirshov pairs and monomial bases for finite dimensional irreducible representations of the simple tie algebra sl$_3$. Each of these monomial bases is in 1-1 correspondence with the set of semistandard Young tableaux with a given shape.

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