• 약학회지
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• 제36권6호
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• pp.538-547
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• 1992

Optimal synthetic condition of barium sulfate were investigated from the viewpoint of yield and bulkiness according to a randomized complete block design proposed by G.E.P. Box and K.B. Wilson. Barium chloride and magnesium sulfate were utilized as reactants in order to prepare barium sulfate in this study. It was found that optimum temperature range of reactant solutions was $60{\sim}100^{\circ}C$ and the optimum concentration range of the reactant solutions was $10{\sim}17.3%$ and $10{\sim}20%$ respectively, on the viewpoint of yield and bulkiness. The optimum mole ratio of $BaCI_2$ to $BaSO_4$ was in the range of $1.50{\sim}2.0$ and the optimum mole ratio of $BaCI_2$ to $BaSO_4$ was in the range of $1.50{\sim}2.0$ and the optimum reacting time range was $15{\sim}20$ minutes. The optimum drying temperature range was $110{\sim}130^{\circ}C$ from the viewpoint of yield, but it was $90{\sim}110^{\circ}C$ on the basis of bulkiness. Apparent viscosity of barium sulfate suspensions dispersed in various concentrations of Na. CMC was measured by using Brookfield synchrolectric viscometer model LVT, the relative equation, log ${\eta}_{sp}=A+B.{\phi}$ was examined and the equation was found to agree fairly well. 1 w/v% Na. CMC aqueous solution and 0.1 volume fraction of $BaSO_4$ powder were optimum in the preparation of $BaSO_4$ suspension showing highest viscosity at infinite shearing.

• 한국임상수의학회지
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• 제6권1호
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• pp.173-184
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• 1989

The effect of propionylpromazine, acepromazine maleate, ketamine HCI, xylazine HCI, and pentobarbital sodium as chemical restraint drugs on the transit time of barium sulfate through the stomach and duodenum in 24 healthy cats was investigated. In the present study, propionylpromazine, acepromazine maleate, and ketamine HCI did not reveal significant effect on the gastroduodenal transit time, but xylazine HCI and pentobarbital sodium pro-longed the gastroduodenal transit time markedly compared with control group. Therefore it is concluded that propionylpromazine, acepromazine maleate, and ketamine HCI could be selected for upper gastrointestinal radiographs. but xylazine HCI and pentobarbital sodium should be avoided.

• 한국방사선학회논문지
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• 제11권5호
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• pp.329-334
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• 2017

본 연구는 의료방사선 차폐를 위해 의료 환경에 적합한 친환경 소재를 찾아 방사선 차폐 시트 제작의 가능성을 추정하고자 하는 것이다. 현재 차폐 소재로 주로 사용되는 납을 대신한 텅스텐 제품이 많이 있으나, 경제성으로 인해 경량의 차폐 시트의 대량생산에는 다소 문제가 있다. 이러한 문제점을 해결하기 위해 경제성 있는 경량 친환경 소재를 필요로 한다. 이러한 소재로써 본 연구에서는 황산바륨과 요오드를 제안하였다. 두 물질은 방사선 촬영에서 이미 조영제로 사용되고 있어 방사선을 흡수하는 특성으로 차폐 재료로써 일정 영역에서 충분히 차폐효과가 있을 것으로 예측하고 있다. 따라서 본 연구에서는 방사선 차폐 재료로 검증하기 위해 몬테카를로 시뮬레이션을 이용하여 모의 추정하였다. 황산바륨과 요오드 등 조영제인 경우 고에너지 영역에서 방사선 흡수효과가 크게 나타나, 의료방사선 고관전압 촬영영역 120 kV의 두께별 에너지영역에서 두 차폐물질의 유효성을 평가하였다. 모의 추정 결과 두 물질 모두 차폐의 유효성을 추정할 수 있었다. 요오드가 황산바륨보다 차폐효과 높았으며, 0.05mm 두께에서는 효과성이 크게 나타났다. 따라서 방사선차폐 시트의 제작 재료로 방사선 조영제인 요오드도 황산바륨과 같이 가능하다는 것을 몬데카를로 시뮬레이션을 통해 확인 할 수 있다.

• 대한디지털의료영상학회논문지
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• 제12권1호
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• pp.15-18
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• 2010

Main component of radiography barrier aprons is lead. To manufacture a lead-free barrier sheath, barium sulfate and organic iodine-based chemicals should be mixed with rubber. Barrier capacity was tested in the medical field. To improve adaptation of rubber with the mixture, raw materials went through milling, agitation, and extruding processes. Three sheaths were manufactured with 30%, 80%, and 120% sulfate barium, respectively. This study found 10% lower barrier capacity of lead-free barrier than the traditional lead-containing rubber sheath. Problems, however, were confronted during the agitation and extruding processes. Mixing with rubber was a technically demanding job. Inconsistent depth, problems with thermal processing and dissipation were encountered as well.

• 대한방사선기술학회지:방사선기술과학
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• 제24권2호
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• pp.53-57
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• 2001

The purpose of this study is to investigate the contamination rate of barium sulfate suspension made in the exposed state in usual circumstances. This study was performed in four university hospital using the contrast media by barium sulfate powder. The specimen were detected at dispensing water, agitator and mixing tank. We also classified the suspension into general bacteria, mycete, and Bacillus coli infection. The tap water were used to dispense water in the all hospitals. Bacillus colt were not detected in the all. General bacteria and mycete were not detected in the one specimen, but detected in two specimen over defined value. In the contamination rate of agitator, mixing tank, and the manufactured, Bacillus coli were not detected in all. However, general bacteria and mycete were detected too numberous to count. In conclusion, the refined water must be used in dispensing water in manufacturing suspension. The disinfectant is also used in washing the agitator and mixing tank for sterilization. Hand washing is indispensible to manufacturing suspension for preventing from infection.

• 대한한방내과학회지
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• 제27권2호
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• pp.459-470
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• 2006

Objectives: The aim of this experimental study is to investigate the effects of MYRISTICAE SEMEN, GRANATI PERICARPIUM and ALPINIAE KATSUMADAI SEMEN on the anticatharsis by using mice and Guinea pigs. Methods : We evaluated the effect of herbs on the extracted organs contraction, the barium sulfate transport, and the anticathartic action induced by acetylcholine chloride, barium chloride, histamine chloride, neostigmine, castor oil, pilocarpine in the ileums, large intestines, small intestines of animals. Results : In the extracted organs, all herbs showed concentration-dependent inhibitory effect on the constriction of extracted ileum. The transport of barium sulfate in the large and small intestine was increased in comparing with the control group. And every three herbs showed the anticathartic action. Conclusions : These results demonstrate that MYRISTICAE SEMEN, GRANATI PERICARPIUM and ALPINIAE KATSUMADAI SEMEN extracts have an advantageous effects on diarrhea induced by drugs and will contribute to the development of diarrhea treatment through further related studies.

• 생약학회지
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• 제20권3호
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• pp.188-195
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• 1989

Hyangsayangwee-Tang, a combined preparation of crude drugs, which has been used for stomach and intestinal disorder, was examined for anti-spasmodic, anti-ulcerative and anti-emetive effects. Spontaneous motility of isolated ileum was strongly suppressed and inhibitory effects against contraction of isolated ileum induced by acetylcholine and barium chloride were shown in mice. And, contraction of isolated guinea-pig ileum by histamine was inhibited. In rats fundus preparations, Hyangsayangwee-Tang elicited strong relaxation and had antagonist effects against the spasm induced by acetylcholine and barium chloride. A significant inhibitory effect on the intestinal propulsion of barium sulfate in mice was shown. In pylorus-ligated rats, Hyangsangwee-Tang inhibited gastric secretion and showed a strong anti-peptic activity. Protective effects against gastric ulceration induced by pyloric ligation, water-immersion stress, histamine and aspirin were significantly recognized in mice and rats. Hyangsayangwee-Tang decreased cupric sulfate-induced vomitting in frogs.

• 대한수의학회지
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• 제35권2호
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• pp.391-398
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• 1995

This study was carried to investigate the usefulness of the radiopaque material as the GI transition and disintegration test of enteric coated capsules radiologically. The obtained results were as follows; 1. The GI transition times that the enteric coated capsules pass through the pylorus were that the time of the first capsule was 210 minutes and the time of the last capsules was more than 300 minutes. Therefore, the GI transition times largely differ from each animal and each enteric coated capsule. 2. The disintegration times of enteric coated capsules were similar in vitro test and in vivo test. 3. The GI transition and disintegration test of enteric coated capsules using barium sulfate, radiopaque material for the gastrointestinal track, was useful to investigate the times that the capsules passed through the pylorus and disintegrated in intestinal track.

• 대한방사선기술학회지:방사선기술과학
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• 제21권1호
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• pp.46-51
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• 1998

The absorption coefficient of contrast media was measured in region of diagnostic radiology. Relative values of absorption coefficient was found the largest peak in the range of $60{\sim}70\;kVp$ for barium sulfate and 60 kVp for iodine. Increasing the thickness of contrast media and patient, the values of absorption coefficient was rising. In the Radiograph, desired $70{\sim}80\;kVp$ in the gastrointestinal digestion tract with barium sulfate and the vascular tract is before and behind 65 kVp of exposure.

• 대한방사선과학회:학술대회논문집
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• 대한방사선과학회 1996년도 추계학술대회
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• pp.95-96
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• 1996