• Nuclear Engineering and Technology
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• 제36권6호
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• pp.528-539
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• 2004

It is essential in commercial reactors that the safety limits imposed on the fuel pellets and fuel clad barriers, such as the linear power density (LPD) and the departure from nucleate boiling ratio (DNBR), are not violated during reactor operations. In order to accurately monitor the safety limits of current reactor states, a detailed three-dimensional (3D) core power distribution should be estimated from the in-core detector signals. In this paper, we propose a calculation methodology for detailed 3D core power distribution, using in-core detector signals and core monitoring constants such as the 3D Coupling Coefficients (3DCC), node power fraction, and pin-to-node factors. Also, the calculation method for several core safety parameters is introduced. The core monitoring constants for the real core state are promptly provided by the core design code and on-line MASTER (Multi-purpose Analyzer for Static and Transient Effects of Reactors), coupled with the core monitoring program. through the plant computer, core state variables, which include reactor thermal power, control rod bank position, boron concentration, inlet moderator temperature, and flow rate, are supplied as input data for MASTER. MASTER performs the core calculation based on the neutron balance equation and generates several core monitoring constants corresponding to the real core state in addition to the expected core power distribution. The accuracy of the developed method is verified through a comparison with the current CECOR method. Because in all the verification calculation cases the proposed method shows a more conservative value than the best estimated value and a less conservative one than the current CECOR and COLSS methods, it is also confirmed that this method secures a greater operating margin through the simulation of the YGN-3 Cycle-1 core from the viewpoint of the power peaking factor for the LPD and the pseudo hot pin axial power distribution for the DNBR calculation.

• International Journal of Knowledge Content Development & Technology
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• 제3권2호
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• pp.67-94
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• 2013

This exploratory research explores the concept of a digital legacy as a general concept and as a collection of digital possessions with unique characteristics. The results reported in this article are part of a larger study. In Cushing (2013), the author identified the characteristics of a digital possession. In this study, these characteristics of a digital possession were utilized to explore how the characteristics of several digital possessions could form a collection, or a digital legacy. In addition to being explored as a collection of digital possessions, data was collected about the general concept of a digital legacy. In part I of the study, 23 participants from three age groups were interviewed about their general concept of a digital legacy. Five general characteristics describing a digital legacy were identified. In part II of the study, interview data from Cushing (2013) was used to create statements describing digital possessions. The statements were classified utilizing the archival concept of primary and secondary values, as well as the consumer behavior concepts of self extension to possessions and possession attachment. Primary value refers to the purpose for which the item was created, while secondary value refers to an additional value that the participants can perceive the item to hold, such as a perception that an item can represent one's identity. Using standard Q method procedure, 48 participants were directed to rank their agreement with 60 statements (written on cards), along a distribution of -5 to +5, according to the characteristics of the digital possession they would most like to maintain for a digital legacy. The ranked statements were analyzed using Q factor analysis, in order to perceive the most common statements associated with maintaining digital possessions for a digital legacy. Q method results suggested that most individuals described the digital possessions they wanted to maintain for a digital legacy using various combinations of characteristics associated with primary and secondary values. This suggests that while some participants will respond to personal archiving based on the concept of preserving identity (a perceived secondary value), this will not appeal to everyone. Information professional could consider this difference in appeal when marketing personal archiving assistance to patrons.

• 한국산업정보학회논문지
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• 제5권2호
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• pp.1-8
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• 2000

인력물자취급(MMH)작업은 작업현장에서 육체적 상해와 요통(LBP)을 발생시키는 주요 원인 중에 하나이며 이러한 산업재해는 점점 증가하고 있는 실정이다. 특히 좋지 않은 작업환경 즉, 비탈진 경사면에 위치한 농장이나 과수원, 항만부두의 하역작업, 경사진 벌목장 작업, 광산의 막장에서의 작업은 많은 재해의 위험성을 초래하며, 신체균형의 상실은 근골격계(musculoskeletal System)의 부상을 초래하게 된다. 본 연구는 경사면에서의 들기작업시 작업자의 근육의 force information과 근피로도를 측정하기 위해 EMG 시스템을 이용하였다. 측정결과 AEMG의 경우 모든 조건에서 일반적으로 multifidus 근육에 걸리는 부하가 다른 근육에서보다 많은 것으로 나타났고, 15$^{\circ}$, 20$^{\circ}$인 경우 neck extensors의 사용이 많은 것으로 나타났다. MPF천이 결과 공통적으로 multifidus부위 근육의 천이정도가 가장 많은 것으로 나타났다. 근육별 부하(%)에 대한 결과는 deep spinal 근육인 multifidus, erectorspinae부위가 상대적으로 많은 것으로 나타났고 neck extensor부위는 근육분담이 적은 것으로 나타났다.

• Molecules and Cells
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• 제41권7호
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• pp.695-702
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• 2018

The inner ear is a complex sensory organ responsible for hearing and balance. Formation of the inner ear is dependent on tight regulation of spatial and temporal expression of genes that direct a series of developmental processes. Recently, epigenetic regulation has emerged as a crucial regulator of the development of various organs. However, what roles higher-order chromatin organization and its regulator molecules play in inner ear development are unclear. CCCTC-binding factor (CTCF) is a highly conserved 11-zinc finger protein that regulates the three-dimensional architecture of chromatin, and is involved in various gene regulation processes. To delineate the role of CTCF in inner ear development, the present study investigated inner ear-specific Ctcf knockout mouse embryos (Pax2-Cre; $Ctcf^{fl/fl}$). The loss of Ctcf resulted in multiple defects of inner ear development and severely compromised otic neurogenesis, which was partly due to a loss of Neurog1 expression. Furthermore, reduced Neurog1 gene expression by CTCF knockdown was found to be associated with changes in histone modification at the gene's promoter, as well as its upstream enhancer. The results of the present study demonstrate that CTCF plays an essential role in otic neurogenesis by modulating histone modification in the Neurog1 locus.

• 한국지능시스템학회논문지
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• 제9권5호
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• pp.555-565
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• 1999

복잡하고 비선형적인 시스템의 규칙베이스 퍼지모델링을 위하여 퍼지시스템의 최적 동정알고리즘을 연구한다. 비선형 시스템은 퍼지모델의 입력변수와 퍼지 입력공간 분할에 의한 구조동정과 파라미터 동정을 통해 표현된다. 본 논문에서 규칙베이스 퍼지모델링은 비선형 시스템을 위해 퍼지추론방법과 두 종류의 최적화 이론의 결합에 의한 하이브리드 구졸를 이용하여 시스템 구조와 파라미터동정을 수행한다. 퍼지모델의 추론방법은 간략추론 및 선형추론에 의한다. 제안된 하이브리드 최적 동정 알고리즘은 유전자 알고리즘과 개선된 콤플렉스 방법을 이용한다. 여기서 유전자 알고리즘은 전반부 퍼지규칙의 멤버쉽함수의 초기 파라미터들을 결정하기 위해 사용되고 강력한 자동동조 알고리즘인 개선된 콤플렉스 방법은 정교한 파라미터들을 얻기 위해 수행된다. 따라서 최적 퍼지모델을 위해 전반부 파라미터 동정에는 하이브리드형의 최적 알고리즘을 이용하고 후반부 동정에는 최소자승법을 이용한다. 또한 학습과 테스트 데이터에 의해 생성된 퍼지모델의 성능결과 사이의 상호균형을 얻기 위해 하중계수를 가지는 합성 성능지수를 제안한다. 제안된 모델의 성능평가를 위해 두가지 수치적 예를이용한다.

• 동의생리병리학회지
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• 제26권4호
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• pp.506-510
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• 2012

Bone homeostasis is regulated by the balance between bone-resorbing osteoclasts and bone-forming osteoblasts. Osteoporosis, rheumatoid arthritis and periodontal disease are related with up-regulated osteoclast formation and its activity. Gol-Swae-Bo(Drynariae Rhizoma) is widely used on skeletal disease. In this study, we sought to examine the effect of Drynariae Rhizoma in RANKL-induced osteoclast differentiation. The extract of Drynariae Rhizoma inhibited RANKL-induced osteoclast differentiation in a dose dependent manner without cytotoxicity. receptor activator of nuclear factor-${\kappa}B$ ligand(RANKL) mediated $I{\kappa}B$ degradation in bone marrow macrophages(BMMs). However, the extract of Drynariae Rhizoma inhibited RANKL induced $I{\kappa}B$ degradation in BMMs. And mRNA expression of OSCAR, TRAP, c-Fos and NFATc1 was suppressed by the extract of Drynariae Rhizoma. Moreover, the extract of Drynariae Rhizoma inhibited the protein expression of NFATc1 and c-Fos induced by RANKL. After all the analysis, these results suggest that Drynariae Rhizoma may be good candidate of medicine in the treatment of bone-related disease.

• Restorative Dentistry and Endodontics
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• 제40권3호
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• pp.202-208
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• 2015

Objectives: This study determined the effect of the air-stream application time and the bonding technique on the dentin bond strength of adhesives with different solvents. Furthermore, the content and volatilization rate of the solvents contained in the adhesives were also evaluated. Materials and Methods:Three adhesive systems with different solvents (Stae, SDI, acetone; XP Bond, Dentsply De Trey, butanol; Ambar, FGM, ethanol) were evaluated. The concentrations and evaporation rates of each adhesive were measured using an analytical balance. After acid-etching and rinsing, medium occlusal dentin surfaces of human molars were kept moist (conventional) or were treated with 10% sodium hypochlorite for deproteinization. After applying adhesives over the dentin, slight air-stream was applied for 10, 30 or 60 sec. Composite cylinders were built up and submitted to shear testing. The data were submitted to ANOVA and Tukey's test (${\alpha}=0.05$). Results: Stae showed the highest solvent content and Ambar the lowest. Acetone presented the highest evaporation rate, followed by butanol. Shear bond strengths were significantly affected only by the factors of 'adhesive' and 'bonding technique' (p < 0.05), while the factor 'duration of air-stream' was not significant. Deproteinization of dentin increased the bond strength (p < 0.05). Stae showed the lowest bond strength values (p < 0.05), while no significant difference was observed between XP Bond and Ambar. Conclusions: Despite the differences in content and evaporation rate of the solvents, the duration of air-stream application did not affect the bond strength to dentin irrespective of the bonding technique.

• 대한전기학회논문지:시스템및제어부문D
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• 제53권6호
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• pp.415-424
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• 2004

In this paper, we introduce and investigate a new category of rule-based fuzzy inference system based on Information Granulation(IG). The proposed rule-based fuzzy modeling implements system structure and parameter identification in the efficient form of “If..., then...” statements, and exploits the theory of system optimization and fuzzy implication rules. The form of the fuzzy rules comes with three types of fuzzy inferences: a simplified one that involves conclusions that are fixed numeric values, a linear one where the conclusion part is viewed as a linear function of inputs, and a regression polynomial one as the extended type of the linear one. By the nature of the rule-based fuzzy systems, these fuzzy models are geared toward capturing relationships between information granules. The form of the information granules themselves becomes an important design features of the fuzzy model. Information granulation with the aid of HCM(Hard C-Means) clustering algorithm hell)s determine the initial parameters of rule-based fuzzy model such as the initial apexes of the membership functions and the initial values of polynomial function being used in the Premise and consequence Part of the fuzzy rules. And then the initial Parameters are tuned (adjusted) effectively with the aid of the improved complex method(ICM) and the standard least square method(LSM). In the sequel, the ICM and LSM lead to fine-tuning of the parameters of premise membership functions and consequent polynomial functions in the rules of fuzzy model. An aggregate objective function with a weighting factor is proposed in order to achieve a balance between performance of the fuzzy model. Numerical examples are included to evaluate the performance of the proposed model. They are also contrasted with the performance of the fuzzy models existing in the literature.

• 한국산학기술학회논문지
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• 제8권1호
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• pp.156-166
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• 2007

대두박은 가축사료에 사용되는 식물성 단백질원이다. 대두박은 대두에서 기름을 추출한 부산물로서 높은 단백질 함량과 낮은 섬유질 함량을 가지고 있어 양돈 사료에서 널리 이용되고 있다. 그러나 이러한 대두는 여러 종류의 항영양인자를 가지고 있어 소화율과 성장능력을 감소시키는 단점을 가지고 있다. 따라서 이러한 단점을 보완하기 위하여 열처리하는 방법, HP 100, HP 200 및 HP 300과 같이 미생물을 이용한 방법, 수용성 비단백질 구성성분을 제거하는 방법, 정제대두단백과 비단백태화합물 제거 등의 방법을 이용하고 있다. 대두를 적당히 열처리를 하면 대부분의 항영양인자가 파괴되어 성돈에서 피해가 없지만 어린돼지에서는 영양소 소화율을 감소시킨다. 그래서 자돈에서는 유제품과 유사한 사양능력을 가지는 농축대두단백이나 정제대두단백 같은 가공대두제품을 이용하여 급여해야 한다.

• 터널과지하공간
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• 제23권3호
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• pp.192-202
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• 2013

최근 유가 상승 및 지구 온난화에 대한 온실가스의 규제 강화로 인해 국내 천연가스 수요가 지속적으로 증가하고 있다. 이에 국내 천연가스 시장의 공급 안전성을 높이기 위하여, 2008년 한국가스공사와 Gazprom 간에 러시아 파이프라인 천연가스 공급에 관한 협약서를 체결하기도 했다. 러시아 PNG 도입계획이 본격화되어 천연가스가 도입되면 겨울철에 가스 수요가 집중되는 국내의 경우엔 천연가스 수급 균형을 위하여 지하저장시설이 필수적으로 요구될 것이다. 본 연구는 암반등급, 토피고, 저장압력, 현지측압계수(Ko)를 변수로 하여 천연가스 저장 공동의 안정성을 정량적으로 평가하였다. 제안된 설계변수에 따른 저장 공동의 거동을 파악하기 위해 축대칭 조건을 사용하여 2차원 응력해석을 수행하였다. 해석 결과 전단강도/전단응력으로 정의된 공동의 안전율은 심도, 암반등급 및 저장압력에 크게 영향을 받았으나 측압계수의 영향은 거의 없었다.