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Development of the Standard Blood Inventory Level Decision Rule in Hospitals (병원의 표준 혈액재고량 산출식 개발)

  • Kim, Byoung-Yik
    • Journal of Preventive Medicine and Public Health
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    • v.21 no.1 s.23
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    • pp.195-206
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    • 1988
  • Two major issues of the blood bank management are quality assurance and inventory control. Recently, in Korea blood donation has gained popularity increasingly to allow considerable improvement of the quality assurance with respect to blood collection, transportation, storage, component preparation skills and hematological tests. Nevertheless the inventory control, the other issue of blood bank management, has been neglected so far. For the supply of blood by donation barely meets the demand, the blood bank policy on the inventory control has been 'the more the better.' The shortage itself by no means unnecessitate inventory control. In fact, in spite of shortage, no small amount of blood is outdated. The efficient blood inventory control makes it possible to economize the blood usage in the practice of state-of-the-art medical care. For the efficient blood inventory control in Korean hospitals, this tudy is to develop formulae forecasting the standard blood inventory level and suggest a set of policies improving the blood inventory control. For this study informations of $A^+$ whole bloods and packed cells inventory control were collected from a University Hospital and the Central Blood Bank of the Korean Red Cross. Using this informations, 1,461 daily blood inventory records were formulated.48 varieties of blood inventory control environment were identified on the basis of selected combinations of 4 inventory control variables-crossmatch, transfusion, inhospital donation and age of bloods from external supply. In order to decide the optimal blood inventory level for each environment, simulation models were designed to calculate the measures of performance of each environment. After the decision of 48 optimal blood inventory levels, stepwise multiple regression analysis was started where the independent variables were 4 inventory control variables and the dependent variable was optimal inventory level of each environment. Finally the standard blood inventory level decision rule was developed using the backward elimination procedure to select the best regression equation. And the effective alternatives of the issuing policy and crossmatch release period were suggested according to the measures of performance under the condition of the standard blood inventory level. The results of this study' were as follows ; 1. The formulae to calculate the standard blood inventory level($S^*$)was $S^*=2.8617X(d)^{0.9342}$ where d is the mean daily crossmatch(demand) for a blood type. 2. The measures of performace - outdate rate, average period of storage, mean age of transfused bloods, and mean daily available inventory level - were improved after maintenance of the standard inventory level in comparison with the present system. 3. Issuing policy of First In-First Out(FIFO) decreased the outdate rate, while Last In-First Out(LIFO) decreased the mean age of transfused bloods. The decrease of the crossmatch release period reduced the outdate rate and the mean age of transfused bloods.

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Comparison of ELLAM and LEZOOMPC for Developing an Efficient Modeling Technique (효율적인 수치 모델링 기법 개발을 위한 ELLAM과 LEZOOMPC의 비교분석)

  • Suk Hee-Jun
    • Journal of Soil and Groundwater Environment
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    • v.11 no.1
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    • pp.37-44
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    • 2006
  • This study summarizes advantages and disadvantages of numerical methods and compares ELLAM and LEZOOMPC to develop an efficient numerical modeling technique on contaminant transport. Eulerian-Lagrangian method and Eulerian method are commonly used numerical techniques. However Eulerian-Lagrangian method does not conserve mass globally and fails to treat boundary in a straightforward manner. Also, Eulerian method has restrictions on the size of Courant number and mesh Peclet number because of time truncation error. ELLAM (Eulerian Lagrangian Localized Adjoint Method) which has been popularly used for past 10 years in numerical modeling, is known for overcoming these numerical problems of Eulerian-Lagrangian method and Eulerian method. However, this study investigates advantages and disadvantages of ELLAM and suggests a change for the better. To figure out the disadvantages of ELLAM, the results of ELLAM, LEZOOMPC (Lagrangian-Eulerian ZOOMing Peak and valley Capturing), and visual MODFLOW are compared for four examples having different mesh Peclet numbers. The result of ELLAM generates numerical oscillation at infinite of mesh Peclet number, but that of LEZOOMPC yields accurate simulations. The simulation results suggest that the numerical error of ELLAM could be alleviated by adopting some schemes in LEZOOMPC. In other words, the numerical model which combines ELLAM with backward particle tracking, forward particle tracking, adaptively local zooming, and peak/valley capturing of LEZOOMPC can be developed for not only overcoming the numerical error of ELLAM, but also keeping the numerical advantage of ELLAM.

A Parametric Study of Pervaporation-facilitated Esterification (전산모델링을 통한 투과증발-촉진 에스테르화 반응에 대한 연구)

  • Yeom, C.K.;Choi, Seung-Hak;Park, You-In;Chang, Sung-Soon
    • Membrane Journal
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    • v.17 no.2
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    • pp.146-160
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    • 2007
  • A parametric study on pervaporation-facilitated esterification was performed by using a practical model based on non-perfect separation through membrane which is not perfectly permselective to water. Thus, membrane selectivity as well as membrane capability to remove water should be taken into account in establishing the simulation model to explain how the membrane separation influence the esterification reaction process. It was shown by simulation that in the reaction systems with non-perfect separation, the permeation of reactants which are acid or/and alcohol retards the reaction by inducing the backward reaction so that reaction conversion curve is located between a reaction system coupled with pervaporation process having a perfect permselectivity to water and a reaction system without pervaporation process. The volume change of reaction system occurs as a result of the permeation through the membrane. The reaction volume change which can be characterized by the reaction ratio of $r_{\Psi}\;to\;r_{{\Psi}=1}$ affects reaction kinetics by concentrating reactants and products, respectively, with different extent with time; reactant-concentrating effect is dominant during the initial stage of reaction, resulting in facilitating the reaction, and then product-concentrating effect is exerted more on reaction, causing to slow down the reaction. When pervaporative dehydration is applied to the reaction system plays an important role in the reaction as well. The effect of timing to impose pervaporation on reaction system affected the reaction kinetics in terms of reaction rate and reaction conversion. A relationship was derived to explain membrane unit capacity and reaction parameters that will be used as a design tool to determine membrane unit capacity at a given reaction conditions or reaction parameters at a membrane unit capacity.

The Study on the Synthesis of Urethane Polymer and Their Application for the Exclusive Use of Soil Layer Transcription and the 1st Transcript of Historical Site (유구 전사 및 토층 전사 전용 우레탄 수지의 합성과 그 적용에 관한 연구)

  • Han, Won-Sik;Wi, Koang-Chul
    • Journal of Conservation Science
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    • v.26 no.3
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    • pp.335-340
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    • 2010
  • Urethane resin applicable for the first transcription of historical site and transcription of soil layer were synthesized in order to replace the imported urethane resin, NS-10. Comparing to the NS-10, the urethane polymers showed similar penetration to wet soil and formed a stable layer of polyurethane during progress working the peeling off the polyurethane pre-product from epoxy surface of final product. The urethane resins used for the first transcription of historical site improved tensile strength, which is consistent with that of NS-10. In addition the urethane resin for transcription of soil layer was supplied with hardness that have a also same strong point as like NS-10. This property is advantage due to simplifying the transcription work of soil layer in backward. When we tested to the real ground soil as well as experimentation compressed soil with use these synthesis urethane resin, we ca get the satisfying result in penetration property and stability and these properties evaluated the resins as an advanced product serving better convenience for worker.

Prevalence and risk factors of subclinical bovine mastitis in some dairy farms of Sylhet district of Bangladesh

  • Kahir, Md. Abdul;Islam, Md. Mazharul;Rahman, A.K.M. Anisur;Nahar, A.;Rahman, Md. Siddiqur;Son, Hee-Jong
    • Korean Journal of Veterinary Service
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    • v.31 no.4
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    • pp.497-504
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    • 2008
  • A cross-sectional study was undertaken to report prevalence and to identify risk factors of subclinical mastitis of dairy cattle in Sylhet district of Bangladesh. Among 325 dairy farms of the district 12 farms(3.7%) were selected conveniently for this study. All the dairy cows of the 12 farms were selected for sample collection. Fresh milk samples from each of the selected dairy cows were collected aseptically in separate sterilized test tube as RF, RH, LF and LH quarter of the udder. Rapid modified White Side Test(WST) was used to detect subclinical mastitis(SCM). Results of WST and data derived from filled in questionnaire were entered in Microsoft Excel 2003 and transferred to $STATA^{(R)}$, version 8.0/Intercooled(Stata Corporation, Texas, USA, 2003). The overall prevalence of SCM and its distribution in different categories of variables in cow and their exact binomial 95% confidence intervals were calculated in $STATA^{(R)}$. Simple bivariable associations among independent variables were investigated by $x^2$ test in $STATA^{(R)}$. Multiple logistic regression analysis with backward elimination method was used to identify risk factors of SCM. To identify significant variation in quarter SCM, linear regression analysis was performed after arcsine transformation of the data. The overall prevalence of SCM found in this study is 54%. Dairy cows with teat lesions had significantly increased SCM(OR=12342, P value=0.000, 95% CI=762, 199798) than others without teat lesions. The Holstein Friesian X Jersey X Sahiwal breed has significantly decreased(OR=0.18, p=0.03, 95% CI 0.04, 0.85) SCM than other breeds. The prevalence of SCM found in this study is in agreement with others. The injury in the teat increases the probability of getting infected with microbes and thereby mastitis. If the prevalence of teat lesion can be decreased the probability of subclinical mastitis will also be decreased. The negatively associated Holstein Friesian X Jersey X Sahiwall breed may help in planning mastitis control program if this finding can be validated by a more powerful case-control or cohort study design.

The Effect of 2008 Beijing Olympic on Korean Air Quality (2008년 북경 올림픽이 한반도 대기질에 미치는 영향)

  • Song, Hyung-Do;Choi, Jin-Soo;Hong, Sung-Chel;Chang, lim-Seok;Kim, Jung-Soo;Lee, Suk-Jo
    • Journal of Environmental Science International
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    • v.18 no.6
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    • pp.655-665
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    • 2009
  • This study aims to identify the impacts of air quality in the Korean Peninsula according to the China's environmental policies in preparation of the Beijing 2008 Olympic Games. The measurement of emission variations in China, aircraft measurement, and modelling were carried out. The reduction measures in Beijing, China and its emission changes resulted in $30{\sim}65%$ in decrease out of the total emissions within the Beijing region, whereas when it comes to the whole nation of China, the reduction rate was about $4{\sim}9%$. Comparing the concentration of the air pollutants in Seoul and Ganghwa in August 2008 during around the period of Beijing Olympic Games with one in $2004{\sim}2007$ showed that the $SO_2$ concentrations in the past was above 5ppb, while the concentration in the 2008 olympic period was 4ppb and below. The NOx at the Seokmori site in Ganghwa tended to be lower in concentration in 2008 than in between $2004{\sim}2007$. As for $O_3$ and $PM_{2.5}$, the concentration tended to be rather low since August 11. The air current track that showed during the period of aircraft measurement presented to be flowed into Korea through the Northeast part of China and the coast of Bohai Bay, while the concentrations of $SO_2$. NOx, and $O_3$ over the west sea on August 20 and 24 were 0.54 (0.28ppb), 0.86 (1.84ppb), and 54.0 (41.5ppb) respectively, similar or lower than the ones measured in the past in the similar current patterns. The modelling result showed similar patterns to the data of aircraft measurement, in particular in $SO_2$. Overall, the reduction measures in Beijing, China affected directly and indirectly the air quality in the Korean peninsular, but the impact was not significant as it was momentary and limited to the intended area.

A Dynamic Service Supporting Model for Semantic Web-based Situation Awareness Service (시맨틱 웹 기반 상황인지 서비스를 위한 동적 서비스 제공 모델)

  • Choi, Jung-Hwa;Park, Young-Tack
    • Journal of KIISE:Software and Applications
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    • v.36 no.9
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    • pp.732-748
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    • 2009
  • The technology of Semantic Web realizes the base technology for context-awareness that creates new services by dynamically and flexibly combining various resources (people, concepts, etc). According to the realization of ubiquitous computing technology, many researchers are currently working for the embodiment of web service. However, most studies of them bring about the only predefined results those are limited to the initial description by service designer. In this paper, we propose a new service supporting model to provide an automatic method for plan related tasks which achieve goal state from initial state. The inputs on an planner are intial and goal descriptions which are mapped to the current situation and to the user request respectively. The idea of the method is to infer context from world model by DL-based ontology reasoning using OWL domain ontology. The context guide services to be loaded into planner. Then, the planner searches and plans at least one service to satisfy the goal state from initial state. This is STRIPS-style backward planner, and combine OWL-S services based on AI planning theory that enabling reduced search scope of huge web-service space. Also, when feasible service do not find using pattern matching, we give user alternative services through DL-based semantic searching. The experimental result demonstrates a new possibility for realizing dynamic service modeler, compared to OWLS-XPlan, which has been known as an effective application for service composition.

A New Secure Multicast Protocol in Micro-Mobility Environments using Secure Group Key (마이크로 모빌리티 환경에서 보안 그룹키를 이용한 안전한 멀티캐스트 프로토콜)

  • Kang, Ho-Seok;Shim, Young-Chul
    • The KIPS Transactions:PartC
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    • v.15C no.6
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    • pp.573-586
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    • 2008
  • The improved performance and miniaturization of computer and the improvement of wireless communication technology have enabled the emergence of many high quality services. Among them multicast services are receiving much attention and their usage is increasing due to the increase of Internet multimedia services such as video conference, multimedia stream, internet TV, etc. Security plays an important role in mobile multicast services. In this paper, we proposed a secure multicast protocol for a hierarchical micro-mobility environment. The proposed secure multicast protocol provides security services such as authentication, access control, confidentiality and integrity using mechanisms including symmetric/asymmetric key crypto-algorithms and capabilities. To provide forward/backward secrecy and scalability, we used sub-group keys based on the hierarchical micro-mobility environment. With this security services, it is possible to guard against all kinds of security attacks performed by illegal mobile nodes. Attacks executed by internal nodes can be thwarted except those attacks which delete packet or cause network resources to be wasted. We used simulator to measure the performance of proposed protocol. As a result, the simulation showed that effect of these security mechanisms on the multicast protocol was not too high.

Spatial Distribution and Variation of Long-range Transboundary Air Pollutants Flux during 1997~2004 (장거리이동 대기오염물질 이동량의 공간적 분포와 변화 추이(1997~2004))

  • Han J. S.;Kim Y. M.;Ahn J. Y.;Kong B. J.;Choi J. S.;Lee S. U.;Lee S. J.
    • Journal of Korean Society for Atmospheric Environment
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    • v.22 no.1
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    • pp.99-106
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    • 2006
  • Aircraft measurements have been executed for the purpose of monitoring the long range transported air pollution and estimation of air pollutant in/out-flux over the Yellow sea. Total 74 missions of measurements have been done since 1997, mainly in spring and fall. The main study domain was over $124^{\circ}$E $/sim$ $124^{\circ}$E, $35^{\circ}$N $/sim$ $37^{\circ}$N below 3,000m. In long-term trends, mixing ratios of $SO_{2}$N were around 2 ppbv expect in summer ( < 1 ppbv). NOx exhibited 24 ppbv and have no clear annual trends over the Yellow Sea. The concentrations of 03 were 51, 58, 41 ppbv in spring, summer and fall-winter, respectively. Backward trajectory was performed for three days to investigate the source regions of the air mass. Six regions were divided around Korea peninsular centering at $36^{\circ}$N, $126^{\circ}$E. I, II, III, IV and V regions represents in sequence northeast China and Siberia, Sandong peninsula and Balhae gulf, Sanghi and southern China, the south Pacific included Jeju island and the East sea included Japan. L region correspond to the airmass from Korea peninsula. Influx of $SO_{2}$N was approximately five times higher than outflux in yearly flux variation and showed a decreasing long-term trend since 1998. NOx outflux was average 0.095 ton/km/hr and three times higher than $SO_{2}$ outflux. In/out flux of 03 showed even distribution in yearly basis except 2002 (influx 5.45 ton/km/hr). The transported amounts from I, II, III regions were much higher than those from other region. In seasonal flux variation, influx levels of gas phases were the lowest in summer and the levels gradually increased from fall toward spring. As a result, transport of pollutants begins from fall and prevails in winter and spring.

A Study on Relapse Predictors in Korean Alcohol-Dependent Patients - A 24 Weeks Follow up Study - (24주 추적 조사를 통한 한국인 알코올 의존 환자의 재발 예측 인자 규명 연구)

  • Kim, Cheol Min;Kim, Sung Gon;NamKoong, Kee;Cho, Dong Hwan;Lee, Byung Ook;Choi, Ihn Geun;Kim, Min Jeong
    • Korean Journal of Biological Psychiatry
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    • v.14 no.4
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    • pp.249-255
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    • 2007
  • Objectives : The aim of this prospective study is to investigate predictors estimating relapse in Korean alcohol-dependent patients using variables like alcohol history, drinking craving, treatment motivation and insight. Methods : Alcohol dependent patients(N=48) who completed questionnaires about sociodemographic variables and drinking history, Timeline Follow-Back(TLFB), Obsessive-Compulsive Drinking Scale(OCSD), Alcohol Urge Questionnaire(AUQ), Pennsylvania Alcohol Craving Scale(PACS), University of Rhode Island Change Assessment(URICA), Hanil Alcohol Insight Scale(HAIS) were followed-up for 24weeks. Subjects who drank heavily(5 standard drinking or more/day) or were not followed up anymore were classified as the relapse group. We used logistic regression analysis with backward elimination of SPSS PC+11.5 to investigate relapse estimate predictors. Results : Average drinking amount per drinking day for last 1 year and HAIS score were predictors of relapse in alcohol-dependent patients. Conclusions : Our findings suggest that therapist should give more attention to alcohol-dependent patients who had more drinks per drinking day for last 1 year and had lower insight level.

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