• 대한물리치료과학회지
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• 제30권4호
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• pp.82-91
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• 2023

Background: Randomized controlled trials (RCTs) provide evidence on the effectiveness and safety of interventions and inform systematic reviews and guideline preparation for clinical application. However, methodological flaws can occur in many RCTs, and Cochrane's risk of bias version 2 (RoB2) can be used to evaluate RCTs' risk of bias (RoB). However, physical therapy RCTs in Korea did not confirm RoB. Therefore, the purpose of this study was to evaluate RoB using RoB2 in RCTs published in the Korean Physical Therapy Journal. Design: Review. Methods: The RCTs subject to evaluation were RCTs published in 11 physical therapy journals in Korea from 2018 to 2022. RoB2 evaluated a total of five domains: bias arising from the randomization process, bias due to deviations from intended interventions, bias due to missing outcome data, bias in measurement of the outcome, and bias in selection of the reported result. Results: A total of 616 RCTs were evaluated. As for bias arising from the randomization process, high risk was the highest at 555 (90.1%), followed by low risk at 41 (6.7%) and some concerns at 20 (3.2%). For bias due to deviations from intended interventions, the proportion of some concerns was the highest at 390 (63.3%), followed by high risk at 218 (35.4%) and low risk at 8 (1.3%). As for the bias due to missing outcome data, the rate of low risk was the highest at 399 (64.8%), followed by high risk at 159 (25.8%) and some concerns at 58 (9.4%). As for bias in measurement of the outcome, high risk was the highest at 294 (47.7%), followed by low risk at 224 (36.4%) and some concerns at 98 (15.9%). In the bias due to missing outcome data, the ratio of high risk was the highest at 610 (99%), followed by low risk at 4 (0.7%) and some concerns at 2 (0.3%). Conclusion: Most of the RoB evaluation results of RCTs published in the Korean Physical Therapy Journal were rated as high risk. Methodological quality of RCTs needs to be improved.

• Journal of Ecology and Environment
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• 제47권4호
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• pp.200-210
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• 2023

Background: Cambaroides similis is an endangered candidate species living in the stream of South Korea. Freshwater crayfish is known to decline rapidly not only domestically, but also internationally. Its decline is projected to be further exacerbated due to climate change. Understanding physical characteristics of the habitat is crucial for the conservation of an organism. However, comprehensive data regarding the distribution and physical habitat characteristics of C. similis are currently unavailable in South Korea. Thus, the objective of this study was to ascertain preferred ranges for water depth, current velocity, and streambed substrate of C. similis using Weibull model. Results: In this study, C. similis was found at 59 sites across 12 regions in South Korea. Its optimal water depth preferences ranged from 11.9 cm to 30.1 cm. Its current velocity preferences ranged from 9.8 cm s^-1 to 29.1 cm s^-1. Its substrate preferences ranged from -5.1 𝜱_m to -2.5 𝜱_m. Median values of central tendency were determined as follows: water depth of 21.4 cm, current velocity of 21.2 cm s^-1, and substrate of -4.1 𝜱_m. Mean values of central tendency were determined as follows: water depth of 21.8 cm, current velocity of 22.0 cm s^-1, and substrate of -4.4 𝜱_m. Mode values of central tendency were determined as follows: water depth of 21.7 cm, current velocity of 20.1 cm s^-1, and substrate of -3.7 𝜱_m. Conclusions: Based on habitat suitability analysis, physical microhabitat characteristics of C. similis within a stream were identified as Run section with coarse particle substrate, low water depth, and slow current velocity. Due to high sensitivity of these habitats to environmental changes, prioritized selection and assessment of threats should be carried out as a primary step.

• Journal of Chest Surgery
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• 제57권1호
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• pp.62-69
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• 2024

Background: Cervical esophageal cancer is a rare malignancy that requires specialized care. While definitive chemoradiation is the standard treatment approach, surgery remains a valuable option for certain patients. This study examined the surgical outcomes of patients with cervical esophageal cancer. Methods: The study involved a retrospective review and analysis of 24 patients with cervical esophageal cancer. These patients underwent surgical resection between September 1994 and December 2018. Results: The mean age of the patients was 61.0±10.2 years, and 22 (91.7%) of them were male. Furthermore, 21 patients (87.5%) had T3 or T4 tumors, and 11 (45.8%) exhibited lymph node metastasis. Gastric pull-up with esophagectomy was performed for 19 patients (79.2%), while 5 (20.8%) underwent free jejunal graft with cervical esophagectomy. The 30-day operative mortality rate was 8.3%. During the follow-up period, complications included leakage at the anastomotic site in 9 cases (37.5%) and graft necrosis of the gastric conduit in 1 case. Progression to oral feeding was achieved in 20 patients (83.3%). Fifteen patients (62.5%) displayed tumor recurrence. The median time from surgery to recurrence was 10.5 months, and the 1-year recurrence rate was 73.3%. The 1-year and 3-year survival rates were 75% and 33.3%, respectively, with a median survival period of 17 months. Conclusion: Patients with cervical esophageal cancer who underwent surgical resection faced unfavorable outcomes and relatively poor survival. The selection of cases and decision to proceed with surgery should be made cautiously, considering the risk of severe complications.

• 한국재난정보학회 논문집
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• 제20권1호
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• pp.93-105
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• 2024

연구목적: 사업장 주변에 배출되는 화학물질의 양을 선정하여 대기확산 프로그램으로 농도를 예측하여 인근 주민들에게 영향을 정량적으로 파악하는 것을 목적으로 하였다. 연구방법: 연구물질의 선정은 반감기, 독성, 이용 가능한 측정소 자료의 유무를 고려하였다. 또한 연구대상물질에서 배출되는 지역을 연구대상 지역으로 선정하였으며, 유동인구가 있는 4개 지역을 선정하여 건강위해성을 평가하였다. 연구결과: AERMOD를 구동하기 위하여 지형 및 기상 처리를 실시 후 예측 농도를 구하였다. 위해성 평가 결과 어린이에서만 디클로로메탄이 초과되는 것으로 나타났으나, 테트라클로로에틸렌과 클로로포름은 어린이와 성인 모두 무시할 수 없는 수준으로 나타났다. 결론: 현재 국내 건강위해성평가는 "환경보건법"의 규정에 따라 위해지수가 일정 기준을 초과할 경우 위해성이 있는 것으로 간주된다. 향후 화학물질배출계획서 대상물질이 2030년에는 415종으로 확대되어 사업장에서 효율적인 관리가 필요함을 시사한다. 위해성 평가에서 위해성지수를 초과하는 경우 대기확산 모델링을 통해 배경농도와 예측농도를 고려하여 우선순위를 부여함으로써 화학물질 관리를 효과적으로 수행할 수 있을 것으로 판단된다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2465-2472
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• 2014

Background: The American Joint Committee on Cancer (AJCC) published a new staging system ($7^{th}$ edition) in 2009. In our study, we evaluated the survival results and prognostic factors among T4 local advanced non-small cell lung cancer (LA-NSCLC) patients in a large heterogeneous group, in accordance with this new system. Materials and Methods: We retrospectively evaluated the files of 122 T4 N0-3 M0 LA-NSCLC patients, identified according to the new staging system, treated at two centers between November 2003 and June 2012. Variables correlating with univariate survival at p<0.20 were later included in multivariate Cox regression analysis. Here, selection of relevant predictors of survival was carried out in accordance with the likelihood ratio formula with p<0.05 regarded as significant. Results: The median age was 60 and the median follow-up period was 17.4 months. Median overall survival (OS) was 18.3 months, the 1 year overall survival (OS) rate was 72%, and the 5 year OS rate was 28%. Statistically significant predictors of survival were (p<0.20) ECOG-PS (Eastern Cooperative Oncology Group Performance Status), age, T4 factor subgroup, stage and primary treatment in OS univariate analysis. On multivariate analysis for OS ECOG-PS (p=0.001), diagnostic stage (p=0.021), and primary treatment (p=0.004) were significant. In the group receiving non-curative treatment, the median OS was 11.0 months, while it was 19.0 months in the definitive RT group and 26.6 months in the curative treatment group. There was a significant difference between the non-curative group and the groups which had definitive RT and curative operations (respectively p<0.001 and p=0.001) in terms of OS, but not between the groups which had definitive RT and curative operations. The median event free survival (EFS) rate was 9.9 months, with rates of 46% and 19% at 3 and 5 years, respectively. On univariate analysis of EFS rate with ECOG-PS, weight loss and staging, statistical significance was found only for thorax computerized tomography (CT)+18F-fluorodeoxy-glucose positron emission tomography-CT (PET-CT) use, stage and primary treatment (p<0.20). In multivariate analysis with EFS, only the primary treatment was statistically significant (p=0.001). In the group receiving non-curative treatment, the median EFS was 10.5 months while in the curative operation group it was 14.7 months. When all the primary treatment groups were taken into consideration, grade III/IV side effect swas observed in 57 patients (46.6%). Esophagitis was most prominent among those that received definitive radiotherapy. Conclusions: Independent prognostic factors among these 122 heterogeneous LA-NSCLC T4 N0-3 M0 patients were age at diagnosis, ECOG-PS, stage and primary treatment, the last also being a significant prognostic indicator of EFS. Our findings point to the importance of appropriate staging and a multidisciplinary approach with modern imaging methods in this patient group. In those with T4 lesions, treatment selection and the effective use of curative potential should be the most important goal of clinical care.

• 핵의학기술
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• 제15권1호
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• pp.94-100
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• 2011

1-day protocol method는 DIAMOX 영상에서 basal 영상을 감산시키는 방법으로 혈관 예비능을 평가하는데 있어서 매우 유용한 검사지만, 검사시간이 길기 때문에 움직임에 의한 불가피한 재검사율이 높다. 기하학적으로 차이가 있는 fan-beam 콜리메이터와 parallel 콜리메이터 중 임상적으로 1-day protocol method에 가장 효율적인 콜리메이터가 무엇인지 알아보았다. 삼중 헤드 감마카메라인 triad XLT 9 (TRIONIX)와 세 가지 콜리메이터(low energy high resolution-parallel beam: LEHR-par, ultra resolution-fan beam: LEUR-fan, super fine-fan beam: LESR-fan)를 사용하였다. PET/SPECT performance phantom, Hoffman 3D phantom, volunteer 실험을 실시하여 세 가지 콜리메이터의 감도, 대조도, 해상력, 영상의 질을 비교 측정하였다. Pixel size를 fan-beam 콜리메이터와 동일하게 하기 위하여 parallel 콜리메이터 실험 시 zoom factor를 2.0으로 변경하였다. Scan time은 50 kcounts/frame을 만족하게 하였으며 filtered back projection (FBP)의 재구성 방법을 사용하였고 각 콜리메이터 별 최적의 영상을 위하여 cut off 값을 변화하면서 비교 측정하였다. 총 획득 계수가 동일한 조건에서 해상력과 percent background variability는 LESR과 LEUR이 LEHR보다 우수한 결과를 나타내었고, 영상의 육안평가에서 선호도는 LESR, LEUR, LEHR 순이었다. 영상 획득 시간은 LESR이 낮은 감도로 인하여 LEUR과 LEHR보다 약 2배 더 길게 소요됐다. Volunteer 실험의 결과 LESR을 사용할 때보다 LEUR 또는 LEHR을 사용 할 때 약 10-14분 정도 시간이 감소했다. 1-day protocol method는 단 한 번의 움직임에도 재검사가 불가피하기 때문에 적절한 분해능뿐만 아니라 높은 감도의 유지를 위해 적절한 검사 방법의 확립이 중요하다 할 수 있다. 본 연구에서 동일한 계수를 획득할 경우 LEUR은 LESR보다 2배의 시간을 감소시킬 수 있었고 영상의 육안평가나 해상력도 LESR과 임상적으로 큰 차이를 보이지 않았으므로 Brain SPECT의 1-day protocol method에 가장 적합할 것으로 사료된다.

• 고전문학과교육
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• 제32호
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• pp.159-191
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• 2016

본 논문에서는 필자가 서울시내 A대학에서 2014년 2학기 국어국문학과 전공선택 과목인 <고전과 창작> 수업시간에 실시한 강의에 근거하여, 수업시간에 실행한 재창작 수업의 과정을 소개하고, 그 과정에서 보여주는 대학생들의 자기성찰 양상을 탐색하고자 하였다. 수업에 참여한 대학생들이 3회의 발표를 통해 만들어낸 작품을 주 분석 대상으로 삼았다. 2장에서는 고전작품 재창작을 위한 수업 진행의 과정으로서 '재창작 작품 선정 배경 및 기획의도 발표', '원작에 대한 분석 및 재창작 사례 탐색', '작품 재창작 및 메타글쓰기'에 대해 논의하였다. 3장에서는 작품 재창작 과정을 통한 대학생의 자기성찰 양상을 탐색해보았다. 학생들이 재창작하고자 하는 고전 작품을 선정하고, 분석하고, 재창작하고, 재창작한 작품에 대한 자기평가에 이르는 과정을 통해서 그들이 가지고 있는 삶에 대한 태도가 어떠한지, 문제가 있다면 그 문제를 대하는 태도와 경향성은 어떠한지 살펴보는 데 역점을 두었다. 수업에 참여한 학생들은 재창작의 대상으로 제각기 서로 다른 작품을 선택하였지만, 이번 논의에서는 <심청전>을 재창작한 두 명의 대학생을 대상으로, 그들이 창작한 작품과 자기 성찰 양상을 비교분석하였다. 그리하여 아버지와의 관계 양상에 따른 창작결과물의 특성에 대해 살펴볼 수 있었다. 고전을 활용한 보다 효과적인 재창작 수업을 위해 작품을 선정하고 보다 체계적이고 다양한 재창작 방법론에 대한 모색이 필요할 것이다. 그러나 고전을 활용한 재창작 수업은 원작의 작품서사를 활용하기 때문에 창작에 대한 부담을 줄일 수 있었고, 자기성찰의 매개가 되는 고전작품을 통해 평소 본인이 고민하는 문제에 대한 깊이 있는 탐색이 가능하다. 또한 공개적인 작품 발표를 통해 보다 객관적인 입장에서 자기서사를 탐색할 수 있고, 피드백을 통해 다른 사람의 의견을 수렴하는 것이 가능하다는 점을 확인할 수 있었다.

• 대한인간공학회지
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• 제35권4호
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• pp.293-305
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• 2016

Objective: This study aims to measure cognitive load levels by analyzing the EEG of Koreans and foreigners, when they read a Korean text with care selected by level from the grammar and vocabulary aspects, and compare the cognitive load levels through quantitative values. The study results can be utilized as basic data for more scientific approach, when Korean texts or books are developed, and an evaluation method is built, when the foreigners encounter them for learning or an assignment. Background: Based on 2014, the number of the foreign students studying in Korea was 84,801, and they increase annually. Most of them are from Asian region, and they come to Korea to enter a university or a graduate school in Korea. Because those foreign students aim to learn within Universities in Korea, they receive Korean education from their preparation for study in Korea. To enter a university in Korea, they must acquire grade 4 or higher level in the Test of Proficiency in Korean (TOPIK), or they need to complete a certain educational program at each university's affiliated language institution. In such a program, the learners of the Korean language receive Korean education based on texts, except speaking domain, and the comprehension of texts can determine their academic achievements in studying after they enter their desired schools (Jeon, 2004). However, many foreigners, who finish a language course for the short-term, and need to start university study, cannot properly catch up with university classes requiring expertise with the vocabulary and grammar levels learned during the language course. Therefore, reading education, centered on a strategy to understand university textbooks regarded as top level reading texts to the foreigners, is necessary (Kim and Shin, 2015). This study carried out an experiment from a perspective that quantitative data on the readers of the main player of reading education and teaching materials need to be secured to back up the need for reading education for university study learners, and scientifically approach educational design. Namely, this study grasped the difficulty level of reading through the measurement of cognitive loads indicated in the reading activity of each text by dividing the difficulty of a teaching material (book) into eight levels, and the main player of reading into Koreans and foreigners. Method: To identify cognitive loads indicated upon reading Korean texts with care by Koreans and foreigners, this study recruited 16 participants (eight Koreans and eight foreigners). The foreigners were limited to the language course students studying the intermediate level Korean course at university-affiliated language institutions within Seoul Metropolitan Area. To identify cognitive load, as they read a text by level selected from the Korean books (difficulty: eight levels) published by King Sejong Institute (Sejonghakdang.org), the EEG sensor was attached to the frontal love (Fz) and occipital lobe (Oz). After the experiment, this study carried out a questionnaire survey to measure subjective evaluation, and identified the comprehension and difficulty on grammar and words. To find out the effects on schema that may affect text comprehension, this study controlled the Korean texts, and measured EEG and subjective satisfaction. Results: To identify brain's cognitive load, beta band was extracted. As a result, interactions (Fz: p =0.48; Oz: p =0.00) were revealed according to Koreans and foreigners, and difficulty of the text. The cognitive loads of Koreans, the readers whose mother tongue is Korean, were lower in reading Korean texts than those of the foreigners, and the foreigners' cognitive loads became higher gradually according to the difficulty of the texts. From the text four, which is intermediate level in difficulty, remarkable differences started to appear in comparison of the Koreans and foreigners in the beginner's level text. In the subjective evaluation, interactions were revealed according to the Koreans and foreigners and text difficulty (p =0.00), and satisfaction was lower, as the difficulty of the text became higher. Conclusion: When there was background knowledge in reading, namely schema was formed, the comprehension and satisfaction of the texts were higher, although higher levels of vocabulary and grammar were included in the texts than those of the readers. In the case of a text in which the difficulty of grammar was felt high in the subjective evaluation, foreigners' cognitive loads were also high, which shows the result of the loads' going up higher in proportion to the increase of difficulty. This means that the grammar factor functions as a stress factor to the foreigners' reading comprehension. Application: This study quantitatively evaluated the cognitive loads of Koreans and foreigners through EEG, based on readers and the text difficulty, when they read Korean texts. The results of this study can be used for making Korean teaching materials or Korean education content and topic selection for foreigners. If research scope is expanded to reading process using an eye-tracker, the reading education program and evaluation method for foreigners can be developed on the basis of quantitative values.

• 한국조경학회지
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• 제48권2호
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• pp.20-33
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• 2020

본 연구는 국제적으로 도시공원의 유산 가치를 인정하고 보존하려는 움직임에 주목하여 국제사회에서 논의되고 있는 도시공원의 보존 동향을 살펴보고자 했다. 국제적으로 '역사적 도시공원' 개념이 등장하게 된 배경과 추진상황을 확인하고, 도시공원의 보존과 관리를 이미 수행하는 영국, 미국, 일본의 사례를 분석하였다. 문화유산의 보전·관리를 중시하는 국제 전문가집단인 ICOMOS에서는 최근 ICOMOS-IFLA 문서를 통해, 역사적 도시공원의 사회적·무형적 가치, 심미적 가치, 생태적 가치, 시민 사회적 가치를 지속하고, 공간 구성, 지형, 빛, 환경과 같은 공원 요소를 보존해야 한다고 하였다. 영국과 미국, 일본은 역사적 도시공원 보존 동향이 나타나게 된 배경, 실제 보존 체계, 보존 대상으로 고려하는 도시공원, 공원 내 보존 요소에 저마다의 특성이 있다. 영국은 시기별로 나타나는 공원의 디자인을 존중하고, 각 시기를 대표하는 공원의 형태 요소를 보존하고자 한다. 미국은 공원의 의미를 물리적 형태뿐 아니라, 문화, 기념성, 사회적 가치 등 다양한 각도에서 파악하여 보존할 공원을 선정하고 관리한다. 일본은 보존 가치가 있는 근대공원을 조사해 선별하고, 공원의 보존 관리를 정책적으로 시행하기 시작했다. 전문가들은 역사적 도시공원의 보존은 기존 정원이나 공원과는 다른 방향으로 이루어져야 한다고 주장한다. 그럼에도 각국 사례를 보면 아직은 문화유산과 도시공원을 다루는 행정과 법제에 따라 물리적 요소를 보존하는데 다소 한정되어 있었다. 변화하는 유산의 개념과 정의의 맥락에서 도시공원의 보존 기준과 방법 또한 발전하고 정교해질 것이다. 도시공원은 역사적으로 여러 가치가 축적된 공간이며, 공원과 도시민의 기억에 많은 역사적 의미를 내재하고 있다. 국제적으로는 이러한 공원의 역사적 가치를 존중하고 보존하는 방향으로 관리가 진행되고 있음을 확인하였다. 도시공원의 가치를 보존하고자 하는 국제 동향은 운영과 관리 문제에 직면한 우리의 도시공원에 시사하는 바가 크다.

• 대한지리학회지
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• 제28권1호
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• pp.16-39
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• 1993

본 연구는 우리나라 都市內 小規模 工業의 立地決定要因을 규명하기 위한 行態的 硏究의 일환으로, 부산시의 소규모 工業經營者들이 都市內部에 공장임지를 결정함에 있어서 실제로 고려하눈 立地要因이 무엇이며, 또한 그 요인은 기업특성, 경영자특성, 입지장소의 용도지역상 성격에 따라 차이가 있는가를 밝히는 데 목적이 있다. 이를 위해 부산시내 소규모 공업경영자들을 대상으로 설문지에 의한 면접조사를 실시하였다. 그 결과, 소규모 공업의 입지결정에 영향을 미치는 요인이 기업의 특성은 물론 경영자 및 용도지역의 특성에 따라 많은 차이가 있음을 확인하였다. 이는 도시내부의 비공업지역에 소규모 공장이 입지함에 있어서 토지를 비롯한 경제적 요인과 더불어 비경제적 요인이 상당한 영향을 미치고 있음은 입지정책에 시사하는 바가 크다고 볼 수 있다.