• The Korean Journal of Pain
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• 제13권1호
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• pp.79-83
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• 2000

Background: Spontaneous intracranial hypotension is a syndrome characterized by postural headache without trauma, spinal anesthesia or other medical history. The purpose of this study is to analyze the effect of epidural blood patch in spontaneous intracranial hypotension. Methods: The spontaneous intracranial hypotension patients treated with epidural blood patch were analyzed on the symptoms, radiologic images and methods of epidural blood patch retrospectively by the medical records. Results: Patients had postural headache (15 patients) including nausea/vomiting (10 patients), tinnitus (2 patients), neck stiffness (13 patients), vertigo (3 patients) and occular pain (1 patient). Brain CT and MRI showed diffuse enhancement of the pachymeninges (9 patients) and radionuclide cisternography demonstrated direct evidence of leakage (11 patients). With epidural blood patch, the symptoms were promptly relieved in 11 patients. Conclusions: We concluded that epidural blood patch is a good treatment of method in spontaneous intracranial hypotension patients.

• Asian Pacific Journal of Cancer Prevention
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• 제14권7호
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• pp.4267-4271
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• 2013

Background: As natural medicines in Asia, curcumin and triptolide extracted from different drug plants have proven to possess anticancer potential and widely used for anti-cancer research. The present study attempted to clarify that curcumin and triptolide synergistically suppress ovarian cancer cell growth in vitro. Methods: To test synergic effects, cell viability and apoptosis were analyzed after curcumin and triptolide combination treatment on ovarian cancer cell lines. Synergistic effects on apoptosis induction were determined by lactate dehydrogenase (LDH) leakage assay, intracellular reactive oxygen species (ROS) assay, mitochondrial membrane potential (MMP) loss assay and flow cytometry analysis. Critical regulators of cell proliferation and apoptosis related were analyzed by qRT-PCR and Western blotting. Results: We showed that the combination of curcumin and triptolide could synergistically inhibit ovarian cancer cell growth, and induce apoptosis, which is accompanied by HSP27 and HSP70, indicating that HSP27 and HSP70 play the important role in the synergic effect. Conclusions: From the result present here, curcumin and triptolide combination with lower concentration have a synergistic anti-tumor effect on ovarian cancer and which will have a good potential in clinical applications.

• 품질경영학회지
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• 제45권3호
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• pp.583-594
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• 2017

Purpose: The purpose of this study is how personal information protection risks affect the intention to use domestic smart banking services. VAM(Value based Adoption Model) model is validated as a theoretical background, selecting ease of use, usefulness and perceived security as a benefit factor, and considers perceived cost, technical complexity, and risk of personal information leakage as a sacrifice factor. Methods: The method of this study used questionnaire survey to collect 365 data on suer's perception on smart banking services, and also performed a structural equation modeling method using by AMOS 23. Results: The result of this paper shows that all hypothesis are accepted statistically significant except 1 hypothesis. Conclusion: This research is concluded that perceived value is affected on statistically positive impact on ease of use, usefulness and perceived security, and negative impact on perceived cost and risk of personal information violation, not statistically technical complexity.

• 한국지구물리탐사학회:학술대회논문집
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• 한국지구물리탐사학회 2007년도 특별 심포지엄 논문집
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• pp.63-72
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• 2007

Current estimates of the ice-mass balance over the Greenland and the Antarctica using retrievals of time-varying gravity from GRACE are presented. Two different GRACE gravity data, UTCSR RL01 and UTCSR RL04, are used for the estimates to examine the impact of the relative accuracy of background models in the GRACE data processing for inter-annual variations of GRACE gravity data. In addition, the ice-mass balance is appraised from the conventional GRACE data, which represents global gravity, and the filtered GRACE data, which isolates the terrestrial gravity effect from GRACE gravity data. The former estimate shows that there exists similar negative trends of ice-mass balance over the Greenland from UTCSR RL01 and UTCSR RL04 while the time series from the both GRACE data over the Antarctica differ significantly from each other, and no apparent trends are observed. The result for the Greenland from the latter calculation is similar to the former estimate. However, the latter calculation presents positive trends of ice-mass balance for the Antarctica from both GRACE data. These results imply that residual oceanic geophysical signals, particularly for ocean tides, significantly corrupt the ice-mass estimate over the Antarctica as leakage error. In addition, the spatial alias of GRACE is likely to affect the ice-mass balance because the spatial spectrum of ocean tides is not conserved via GRACE sampling, and thus ocean tides contaminate terrestrial gravity signal. To minimize the alias effect, I suggest to use the combined gravity models from GRACE, SLR and polar motion.

• 대한기관식도과학회지
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• 제8권1호
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• pp.61-65
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• 2002

Background : Acquired tracheoesophageal fistula(TEF) results mostly from Prolonged tracheal intubation and insertion of nasogastric tube. Although the incidence has decreased since the usage of low pressure, high volume cuff of endotracheal tube, it is seldom cured spontaneously and needs surgical treatment. Material and Methods : We have retrospectively reviewed five cases of TEF who underwent surgical treatment for cure from March, 1990 to September, 2001 and analyzed the cause, treatment, postoperative complications and prognostic factors. Results : Majority were men(80% : 4 of 5 patients) and the mean age was 29.4 years old(range, 11-58). The most predominant etiology was prolonged intubation or tracheostomy(80% : 4 of 5 patients) and 3 of 5 patients were treated by tracheal resection and end to end anastomosis with primary closure of esophagus. Postoperative complications occurred in 4 patients the most common complications were wound infection(4 cases) and esophageal leakage(2 cases). Extubation was done on postoperative day 11.5(range, 1-33) days, and factors causing delayed extubation were status esophagus. epilepticus, edema, and tracheal stenosis. Conclusion : Spontaneous closure of TEF is seldom possible and the surgical treatment of choice is tracheal resection and end to end anastomosis with primary repair of the esophagus. preoperative pulmonary rehabilitation and early extubation postoperatively are important factors for success.

• Applied Science and Convergence Technology
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• 제25권6호
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• pp.124-127
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• 2016

Humidity calibration for a temperature-stable quartz oscillator (TSQO) was investigated to exclude the influences of relative humidity on the TSQO output in order to use the corresponding devices outdoors. The TSQO output is a voltage that is inversely proportional to the electric impedance of the quartz oscillator, which depends on the viscosity and density of the measured gas. The TSQO output was humidity calibrated using its humidity dependence, which was obtained by varying the relative humidity (RH) from 0 to 100 RH% while other conditions were kept constant. The humidity dependencies of the TSQO output were fit by a linear function. Subtracting the change in the TSQO output induced by the change in humidity, calculated with the function from the experimentally measured TSQO output for a range of 0-100RH%, eliminated the influence of humidity on the TSQO output. The humidity calibration succeeded in reducing the fluctuations of the TSQO output from 0.4-3% to 0.1-0.3% of the average values for a range of 0-100RH%, at constant temperatures. The necessary stability of the TSQO output for application in hydrogen sensors was below one-third of the change observed for a hydrogen leakage of 1 vol.% hydrogen concentration, corresponding to 0.33% of the change in each background. Therefore, the results in this study indicate that the present humidity calibration effectively suppresses the influence of humidity, for the TSQO output for use as an outdoor hydrogen sensor.

• 한국안전학회지
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• 제27권3호
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• pp.111-116
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• 2012

This study is about the quantitative safety assessment of hydrogen station in Korea operating with on-site type. This was written by background information that before qualitative safety assessment to write. For the qualitative safety assessment method, the study used FMEA(failure mode & effect analysis) and HAZOP(hazard & operability), and adopted the FTA(fault tree analysis) as the quantitative safety assessment method. To write the FTA, we wrote FT by Top event that hydrogen leakage can be called most serious accident of hydrogen station. Each base event collect reliability data by reliability data handbook, THERP-HRA and estimation of the engineering. Assessment looked at the high frequency and the possible risk through Gate, Importance, m.cutsets analysis.

• 대한두개안면성형외과학회지
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• 제22권5호
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• pp.232-238
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• 2021

Background: Galeal or temporalis muscle flaps have been traditionally used to reconstruct skull base defects after tumor removal. Unfortunately, these flaps do not provide sufficient vascularized tissue for a dural seal in extensive defects. This study describes the successful coverage of large skull base defects using anterolateral thigh (ALT) free flaps. Methods: This retrospective study included five patients who underwent skull base surgery between June 2018 and June 2021. Reconstruction was performed using an ALT free flap to cover defects that included the intracranial space and extended to the frontal sinus and cribriform plate. Results: There were no major complications, such as ascending infections or cerebrospinal leakage. Postoperative magnetic resonance imaging showed that the flaps were well-maintained in all patients. Conclusion: Successful reconstruction was performed using ALT free flaps for large anterior skull base defects. In conclusion, the ALT free flap is an effective option for preventing communication between the nasal cavity and the intracranial space.

• Archives of Plastic Surgery
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• 제48권3호
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• pp.254-260
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• 2021

Background Myelomeningocele is a frequently seen condition at tertiary care hospitals. Its treatment involves a variety of plastic reconstructive techniques. Herein, we present a series of myelomeningocele patients treated using keystone flaps. Methods We gathered information regarding soft tissue reconstruction and the use of bilateral keystone flaps to treat myelomeningocele patients. We obtained data from clinical records and recorded the demographic characteristics of mothers and children with the condition. The size, level of defect, and complications detected during the follow-up were analyzed. Results A series of seven patients who underwent bilateral keystone flaps for myelomeningocele closure was analyzed. There were no cases of midline or major dehiscence, flap loss, necrosis, surgical site infections, or cerebrospinal fluid leakage. No revision procedures were performed. Minor complications included one case with minimal seroma and three cases with areas of peripheral dehiscence that healed easily using conventional measures. Conclusions The use of keystone flaps is an adequate option for closure of dorsal midline soft tissue defects related to myelomeningocele. This technique offers predictable results with an acceptable spectrum of complications. Robust blood flow can be predicted based upon anatomical knowledge.

• Journal of Chest Surgery
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• 제42권3호
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• pp.344-349
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• 2009

배경: 기흉 환자에 있어서 임상양상은 기흉의 양과 폐의 상태에 많은 영향을 받는다. 따라서 기존 폐질환이 없는 일차성 자연 기흉에서의 대량 기흉은 증상이 심할 수 있으므로 적극적인 치료가 필요할 것이다. 그러나 대량 기흉에 있어서의 치료 방침이 병원마다 다양하다. 따라서 외과적 치료를 시행한 일차성 자연기흉 환자의 임상소견을 분석하여 향후 치료의 지표로 삼고자 한다. 대상 및 방법: 2004년 8월부터 2007년 12월까지 일차성 자연기흉으로 치료를 시행한 348명의 환자 중 대량 기흉 환자 58명을 대상으로 후향적 조사를 통하여 흉강경소견 및 치료 결과를 분석하였다. 긴장성 기흉을 포함하여 흉부엑스선상 기흉의 양이 80% 이상인 경우를 대량 기흉으로 분류하였다. 이들 모두에게 12 F 흉관을 이용한 흉관삽입술을 먼저 시행하였다. 재발성, 지속적인 공기누출, 반대편 기흉의 과거력이 있는 경우에는 수술적 치료를 시행하였고, 초발인 경우에는 흉부단층촬영 소견상 1 cm 이상의 폐기 포가 관찰되었을 때 흉강내시경을 이용한 수술적 치료를 시행하였다. 결과: 대상환자는 남자 50명, 여자 8명 이었고, 평균 연령은 28.2세$(14\sim54)$였다. 평균 입원기간은 5.3일$(2\sim10)$이었다. 49예에서 흉강내시경 수술을 시행하였고 총판치료만 시행한 경우는 9예였다. 추적기간은 평균 27.8개월$(10\sim58)$ 이었다. 술 장에서의 공기누출은 35예(71.4%)에서 관찰되었으며, 공기누출에 영향을 주는 인자를 분석한 결과 흉막유착과 유의한 상관관계를 보였다(p=0.005). 술 전 공기누출이 있는 경우 술 장에서 공기누출이 발견된 경우가 많았으나 통계적 유의성은 없었다(p=0.066). 재발율은 흉관 삽입치료를 시행한 9예 중 1예(11.1%), 수술을 시행한 49예 중 1예(2.0%)였다. 결론: 대량 일차성 자연기흉은 조기 진단 및 조기 치료가 필요하다. 흉강내시경 수술이 대량 기흉의 치료 후 재발을 방지하는데 많은 도움이 될 것이다.