• Title/Summary/Keyword: awake

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Measurement and Analysis of Rodent Biological Signals using Telemetry System (원격측정장치를 이용한 설치류의 생체신호 측정 및 분석)

  • Kim, Chang-Hwan;Hur, Gyeong-Haeng
    • Journal of the Korea Institute of Military Science and Technology
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    • v.14 no.6
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    • pp.1159-1165
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    • 2011
  • Telemetry techniques of rats have been used for assessing safety pharmacology of drugs and chemicals. Biological signals including blood pressure and heart rate measured under anesthesia were significantly different from those obtained under normal conditions. The stress of restraint in awake animals can also affect the accuracy of physiological evaluation. This paper details the surgery required to allow key cardiovascular parameters to be determined. The telemetric measurement of cardiovascular parameters such as blood pressure, heart rate, electrocardiograph(ECG) established. We carried out the continuous monitoring of cardiovascular parameters using the telemetry system in F344 rats. During the measurement, no significant changes were observed in the heart rate and blood pressure. ECG signals and body temperature were also constant during the measurement of biological signals. With the results of this study, we conclude that this telemetry system can be applied usefully for the assesment of biological parameters in the rats.

Imaging Diagnosis of Emphysematous Pyelonephritis in a Non-Diabetic Dog

  • Kim, Heesu;Lee, Kija;Chung, Jinyoung;Ahn, Jinok;Park, Inchul;Choi, Sooyoung
    • Journal of Veterinary Clinics
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    • v.37 no.4
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    • pp.231-234
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    • 2020
  • An 11-year-old, 4.3 kg, mixed breed, intact female dog exhibiting vomiting and a reduced appetite was presented. On physical examination, palpation of the right kidney elicited discomfort. Blood analysis revealed leukocytosis with neutrophilia, and elevation of alkaline phosphatase and blood urea nitrogen. Escherichia coli was detected in urine culture, whereas urine analysis showed absence of glucose. Radiography and ultrasonography suggested that there was gas in the right renal parenchyma, and computed tomography was performed while the dog was awake to investigate the suspected gas in the right kidney. After unilateral ureteronephrectomy, a histological diagnosis of right emphysematous pyelonephritis (EPN) was made. EPN refers to a severe necrotizing infection of the renal parenchyma with gas accumulation in the tissue. It is rare in both human and veterinary medicine, and almost all EPN patients have uncontrolled diabetes mellitus. This case report describes the imaging-based diagnosis of a rare occurrence of unilateral EPN in a non-diabetic dog.

Maintenance of Wakefulness and Occupational Injuries among Workers of an Italian Teaching Hospital

  • Valent, Francesca;Sincig, Elisa;Gigli, Gian Luigi;Dolso, Pierluigi
    • Safety and Health at Work
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    • v.7 no.2
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    • pp.120-123
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    • 2016
  • Background: To assess in a laboratory setting the ability to stay awake in a sample of workers of an Italian hospital and to investigate the association between that ability and the risk of occupational injury. Methods: Nine workers at the University Hospital of Udine who reported an occupational injury in the study period (cases), and seven noninjured workers (controls) underwent a polysomnography and four 40-minute maintenance of wakefulness tests (MWT). Differences in sleep characteristics and in wakefulness maintenance were assessed using Wilcoxon's rank sums tests and Fisher's exact tests. Results: Controls had greater sleep latency, lower total sleep time, fewer leg movements, and a higher percentage ratio of cycling alternating pattern, were more likely not to fall asleep during the MWT and were less likely to have two or more sleep onsets. Although not all the differences reached statistical significance, cases had lower sleep onset times in Trials 1-3. Conclusion: In the literature, the evidence of an association between MWT results and real life risk of accidents is weak. Our results suggest a relationship between the MWT results and the risk of injury among hospital workers.

The Impact of Ethical Leadership on Employees' Innovative Behaviours

  • KIM, Chan-Eon;LEE, Bum-Suk;LEE, Jaemin
    • The Journal of Economics, Marketing and Management
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    • v.9 no.4
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    • pp.19-30
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    • 2021
  • Purpose: This study aimed to examine how a superior employee's ethical leadership affects members' innovative behaviors, mainly on organization-based self-esteem. It also aimed to verify the mediating effect of organization-based self-esteem in the process that ethical leadership affects members' innovative behavior in distribution-related organizations. Research design, data and methodology: After collecting materials from companies' executives and staff members in distribution-related organizations located in Seoul, South Korea, a research hypothesis was analyzed. Results: A superior employee's ethical leadership affects a positive (+) effect on innovative behaviors of the organization's members and the study confirmed that the relation of this effect was mediated by organization-based self-esteem. It means that the possibility that an organization's members will do innovative behaviors will be increased if a leader conducts ethical leadership. It also means that a leader with ethical leadership enables an organization's members to pay attention all the time and be awake for their work environment. Conclusions: The result of this study discusses how ethical leadership affects innovative behaviors of an organization's members from the perspective of organization-based self-esteem and has a theoretical implication that it has empirically examined it. More importantly, it has a theoretical implication because it verified how this effect was made using organization-based selfesteem and flexible human resource management.

Clinical Applications of Office-Based Laryngeal Surgery With KTP Laser (KTP 레이저를 이용한 외래 기반 후두 수술의 임상적 적용)

  • Cho, Jung-Hae
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.32 no.3
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    • pp.118-123
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    • 2021
  • The pulsed photoangiolytic 532-nm potassium-titanyl-phosphate (KTP) laser has emerged in recent years as an efficacious treatment modality for vocal fold lesions. It also has broadened the indications for other laryngeal laser surgery. Features of KTP laser that it is a fiber-based delivery system and its energy is selectively absorbed by oxyhemoglobin make it suitable for office-based laryngeal procedures. An office-based KTP laser surgery provides an alternative management option for benign laryngeal diseases and can be performed comfortably under flexible endoscopic guidance which is placed through the nose of a fully awake patient. Office-based laryngeal surgery with a KTP laser can alleviate the need for general anesthesia. However, there are some limitations to apply due to reduced visual precision and the fact that the vocal folds are moving during procedures. Clinicians should carefully weigh the advantages and disadvantages of office-based procedures before a treatment option is selected. Patient selection and standardized laser energy parameters may help in decreasing complications and improving the treatment results.

Why most patients do not exhibit obstructive sleep apnea after mandibular setback surgery?

  • Kim, Jin-Wook;Kwon, Tae-Geon
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.7.1-7.8
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    • 2020
  • Maxillomandibular advancement (MMA) is effective for the treatment of obstructive sleep apnea (OSA). In previous studies, the airway was increased in the anteroposterior and transverse dimensions after MMA. However, the effect of the opposite of mandibular movement (mandibular setback) on the airway is still controversial. Mandibular setback surgery has been suggested to be one of the risk factors in the development of sleep apnea. Previous studies have found that mandibular setback surgery could reduce the total airway volume and posterior airway space significantly in both the one-jaw and two-jaw surgery groups. However, a direct cause-and-effect relationship between the mandibular setback and development of sleep apnea has not been clearly established. Moreover, there are only a few reported cases of postoperative OSA development after mandibular setback surgery. These findings may be attributed to a fundamental difference in demographic variables such as age, sex, and body mass index (BMI) between patients with mandibular prognathism and patients with OSA. Another possibility is that the site of obstruction or pattern of obstruction may be different between the awake and sleep status in patients with OSA and mandibular prognathism. In a case-controlled study, information including the BMI and other presurgical conditions potentially related to OSA should be considered when evaluating the airway. In conclusion, the preoperative evaluation and management of co-morbid conditions would be essential for the prevention of OSA after mandibular setback surgery despite its low incidence.

Trigger Wrist with Carpal Tunnel Syndrome Accompanied with Trifid Median Nerve: A Case Report and Literature Review

  • Sangho Oh
    • Archives of Plastic Surgery
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    • v.49 no.6
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    • pp.750-754
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    • 2022
  • Trigger wrist, characterized by a clicking or snapping sensation around the wrist joint during finger or wrist motion, and bifid or trifid median nerve, which occurs in carpal tunnel syndrome along with anatomical variation of median nerve, are rare conditions. We report the case of a patient with a thickened tendon caused by severe tenosynovitis and flexor tendon subluxation to the hamate hook due to bowing of the flexor retinaculum, thereby resulting in trigger wrist as well as an anatomical median nerve variation (bifid median nerve in the right wrist and trifid median nerve in the left wrist). A 59-year-old housewife visited our hospital with bilateral fingertip numbness, tingling sensation, and aggravated severe night cramping that began 2 months ago. She also complained about trigger wrist during small finger flexion. Based on magnetic resonance imaging, ultrasonography, and nerve conduction study, trifid median nerve and bilateral severe median nerve neuropathy of the wrist were diagnosed; therefore, transverse carpal tunnel release and exploration under wide-awake anesthesia were planned. Intraoperative findings showed trifid and bifid median nerves in left and right wrists, respectively. Additionally, bowing of flexor retinaculum and severe flexor tendon tenosynovitis were observed. Tenosynovitis with thickened flexor sheath resulted in subluxation of the small finger flexor tendon above the hamate hook. After transverse carpal ligament release with antebrachial fascia release and tenosynovectomy, subluxation of the flexor tendon was resolved. At 6 months postoperatively, the tingling and dullness in fingertips also resolved, and no trigger wrist or any other complications were noted.

Clinical Study on Effect of Auricular acupuncture theraphy and Auricular acupuncture theratphy with common acupuncture theraphy(Shinmum HT7) on Insomnia in stroke patients (뇌혈관장애환자의 불면증에 대한 이침요법과 신문혈자침 병행시술의 치료효과에 대한 비교연구)

  • So, Woong-ryong;Park, Won-tae;Lee, Sun-ho;Sin, Kyung-ho;Roh, Jeong-du;Choi, Seok-woo;Kim, Jae-gwan
    • Journal of Acupuncture Research
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    • v.20 no.5
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    • pp.38-49
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    • 2003
  • Objective: This study is aimed to compare the change of clinical comfort and improvement after auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7) on insomnia in stroke patients. Methods : Clinical study was carried out on 40 stroke patients who was traeted insomnia by auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7) at Kwang-Dong Oriental Medical Hospital. Results: 1. Total sleeping time was increased in auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7). 2. Average delaying time before sleep and Average Awake Times was decreased in auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7). 3. Quality of sleep was improved in auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7). 4. Insomnia Score was increased in auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7). Conclusions : According to the results, both auricular acupuncture theraphy and auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7) were effective on insomnia in stroke patient. but, auricular acupuncture theraphy was more effective than auricular acupuncture theraphy with common acupuncture theraphy(Shinmun HT7) in total sleeping time and insomnia score.

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Improvement of a Context-aware Recommender System through User's Emotional State Prediction (사용자 감정 예측을 통한 상황인지 추천시스템의 개선)

  • Ahn, Hyunchul
    • Journal of Information Technology Applications and Management
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    • v.21 no.4
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    • pp.203-223
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    • 2014
  • This study proposes a novel context-aware recommender system, which is designed to recommend the items according to the customer's responses to the previously recommended item. In specific, our proposed system predicts the user's emotional state from his or her responses (such as facial expressions and movements) to the previous recommended item, and then it recommends the items that are similar to the previous one when his or her emotional state is estimated as positive. If the customer's emotional state on the previously recommended item is regarded as negative, the system recommends the items that have characteristics opposite to the previous item. Our proposed system consists of two sub modules-(1) emotion prediction module, and (2) responsive recommendation module. Emotion prediction module contains the emotion prediction model that predicts a customer's arousal level-a physiological and psychological state of being awake or reactive to stimuli-using the customer's reaction data including facial expressions and body movements, which can be measured using Microsoft's Kinect Sensor. Responsive recommendation module generates a recommendation list by using the results from the first module-emotion prediction module. If a customer shows a high level of arousal on the previously recommended item, the module recommends the items that are most similar to the previous item. Otherwise, it recommends the items that are most dissimilar to the previous one. In order to validate the performance and usefulness of the proposed recommender system, we conducted empirical validation. In total, 30 undergraduate students participated in the experiment. We used 100 trailers of Korean movies that had been released from 2009 to 2012 as the items for recommendation. For the experiment, we manually constructed Korean movie trailer DB which contains the fields such as release date, genre, director, writer, and actors. In order to check if the recommendation using customers' responses outperforms the recommendation using their demographic information, we compared them. The performance of the recommendation was measured using two metrics-satisfaction and arousal levels. Experimental results showed that the recommendation using customers' responses (i.e. our proposed system) outperformed the recommendation using their demographic information with statistical significance.

The Effects of Acupuncture at the GV20 and GV22 on the Electroencephalogram(EEG) (백회(百會)(GV20).신회(顖會)(GV22) 자침이 뇌파에 미치는 영향)

  • Lee, Sang-Hun;Ryu, Yeon-Hee;Kwon, O-Sang;Sohn, In-Chul
    • Korean Journal of Acupuncture
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    • v.29 no.3
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    • pp.467-475
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    • 2012
  • Objectives : The aim of this study was to examine the effects of Acupuncture at the GV20 and GV22 on normal human beings using power spectrum analysis. Methods : Electroencephalogram(EEG) power spectrum exhibits site-specific and state-related differences in various frequency bands. 8 channels Background Electroencephalogram (EEG) was carried out in 30 subjects(24 females and 4 males). Results : In ${\delta}$(theta) band, the power values decreased significantly at the 8-channel average value(p=0.03) and especially at T3(p=0.02), T4(p=0.001) and P3(p=0.03). In ${\alpha}$(alpha) band, the power values have no significant changes. In ${\beta}$(beta)band, the power values increased significantly at the 8-channel average value (p=0.02) and especially at T4(p=0.003), P3 (p= 0.03) and P4(0.02). In ${\beta}/{\delta}$(beta/theta) ratio, the value increased significantly at the 8-channel average value(p=0.002) and especially at Fp2(p=0.05), F4(p=0.007), T3(0.012), T4(0.005), P3 (0.007) and P4(0.03) Conclusions : Through this data, we conclude that acupuncture at the GV20 and GV22 on normal human beings could have possibility to awake the cerebral cortex by the functional mechanism.