Toxoplasmosis is an important cause of foodborne, inflammatory illnesses, as well as congenital abnormalities. Currently available therapies are ineffective for persistent chronic disease and congenital toxoplasmosis or have severe side effects which may result in life-threatening complications. There is an urgent need for safe and effective therapies to eliminate or treat this cosmopolitan infectious disease. The aim of this study was to investigate the in vitro anti-Toxoplasma activities of Plantago asiatica L., one of the herbal extracts, using tachyzoit of T. gondii RH strain infected HeLa cells. As the results, the selectivity of Plantago asiatica L. extract was 4.5, which was higher than Sulfadiazine selectivity (0.4). Also, we perfomed the cell proliferation inhibition test and the morphological study to evaluate the anti-T. gondii activity of Plantago asiatica L. extract with HeLa cells. As the results, the inhibition rate of the Plantago asiatica L. extract was high inhibition rate. This indicates that the Plantago asiatica L. extract may be used for new anti-T. gondii agent.
To increase the consumer acceptability of yam and the shelf-life of fresh-cut yam, organic acid-treated fresh-cut yam was prepared. When uncontaminated fresh-cut yam was stored at $4^{\circ}C$ for 14 days after treatment with 1% (v/w) organic acids, the browning and microbial putrefaction of fresh-cut yam were inhibited by treatment of acetic acid or maleic acid, whereas treatment of citric acid and ascorbic acid, commonly used browning inhibitors in food industry, did not show apparent effects on the browning and putrefaction of yam. The Inhibitory effects of acetic acid or maleic acid were superior than those of NaOCl (100 ppm), hydrogen peroxide (100 ppm) or commercially available washing solution. Also, treatments of 1% acetic acid, or 1% maleic acid Into artificially-contaminated yam $(10^5\;CFU/g-yam)$ showed strong inhibition of browning and putrefaction during long term storage at $4^{\circ}C$. The growth inhibition test indicated that 0.1% is enough to inhibit the growth of psychrotrophic yam-putrefactive Pseudomonas sp., and treatment of 0.1% acetic acid, or 0.1% maleic acid inhibited the browning and microbial putrefaction of fresh-cut yam. Our results suggested long-term distribution of yam or other root crops products is possible by treatment of organic acid, such as acetic acid, combined with aseptic vacuum packaging technology.
Kim, Mi-Sun;Lee, Ye-Seul;Kim, Jong Sik;Shin, Woo-Chang;Sohn, Ho-Yong
Microbiology and Biotechnology Letters
/
v.42
no.3
/
pp.258-266
/
2014
Sweet potato soju (SPS), a form of traditional distilled alcoholic liquor in Korea, is manufactured by the distillation of fermented broth under normal pressure, thus providing it for a uniquely smooth taste infused with the flavor of sweet potato. After distillation, the lees of SPS is produced as by-product and discarded. In this study, the ethanol and hot water extracts of lees of SPS, and their subsequent organic solvent fractions using hexane, ethylacetate (EA), butanol, and water residue were prepared in an effort at the efficient re-use of the lees of SPS. The ethanol extraction yield was 1.36-fold higher than that of the hot water extraction, and the EA fraction revealed the highest total polyphenol content among the solvent fractions. The various extracts and solvent fractions did not demonstrate hemolytic activity at up to 0.5 mg/ml concentrations against human red blood cells. In the bioactivity assay, only the EA fraction displayed a broad spectrum of anti-microbial activity against different pathogenic and food spoilage bacteria, and demonstrated significant anti-coagulation activity by inhibitions of thrombin, prothrombin and blood coagulation factors. Furthermore, only the EA fraction from the hot water extract of the lees of SPS showed anti-platelet aggregation activity, which is comparable to aspirin (a commercially available drug). Our results suggest that the EA fraction of the hot water extract prepared from the lees of SPS has a high potential as a novel resource for anti-microbial and anti-thrombosis agents.
Journal of Korean Society of Environmental Engineers
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v.22
no.4
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pp.699-712
/
2000
Juam lake is a major water resource for the industrial and agricultural activities as well as the resident life of Kwangju and Chonnam regions. However, the water quality of the lake is getting worse due to a large quantity of pollutant inflowing to the lake. Thus, the strategy for achieving the water quality goal of the lake should be developed as soon as possible. When there are various alternatives that can be used as the strategy, several criteria based on the achievement degree of water quality goal, the applicability of technique and social environment, and the reasonableness of the cost required are made to evaluate and rank the alternatives. However, it is difficult to make a decision when there are multiple criteria and conflicting objectives and specifically the estimated values of criteria contain elements of uncertainty. The uncertainty stems from the lack of available information, the randomness of future situation, and the incomplete knowledge of expert. As the degree of uncertainty is higher, the decision becomes more difficult. In this study, a fuzzy decision-making method is presented to assist decision makers in evaluating various alternatives under uncertainty. The method allows decision makers to characterize the associated uncertainty by applying fuzzy theory and incorporate the uncertainty directly into the decision making process for selecting the "best" alternative so decisions can be made that are more appropriate and realistic than those made without taking uncertainty in account.
Song Ho-Sueb;Kang Mi-Jung;Lim Jeong-Eun;Kwon Soon-Jung;Kang Mi-Suk;Lee Seong-No;Byun Im-Jeung;Hwang Hyeon-Seo;Kim Kee-Hyun
Journal of Acupuncture Research
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v.18
no.6
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pp.1-13
/
2001
Objective : To broaden understanding about relationship between Meridian Tendino-musculature and muscles in a lumbar area and to evaluate the effect of Meridian Tendino-musculature acupuncture and release therapy on acute lumbar sprain. Materials and Methods : From Oct. 1st, 2000 to Mar. 31th, 2001, 692 outpatient's chart of Kyung Won University Hospital were reviewed. Out of them, 39 outpatients were selected. they had low back pain, were diagnosed with acute lumbar sprain, showed only straightened curvature on lateral view of lumbar spine X-ray and get the Tendino-musculature acupuncture and release therapy. Results : 1. On patients' first visit, 72% had GrIII and Gr.IV predominantly. 2. Major muscles related with low back pain were divided into two groups. One was Quadratus lumborum group and the other was Rectus abdominis group. In the correlation with Meridian Tendino-musculature, the former was mainly related with Chok-taeyang(B) and slightly related with Chok-soyang(G), Chok-taeum(SP), the latter was mainly related with Chok-taeyum(SP), Chok-yangmyong(S) and slightly related with Chok-taeyang(B), Chok-soyang(G). 3. In the evaluation of treatment effect, Exellent was 27(69%), Good was 10(6%), Fair was 2(5%) and Bad was 0(0%). Fair rate reached 100% eventually. 4. Most of Gr.Ⅲ, Gr.Ⅳ patients who had severe conditions that almost every R.O.M. was limited and Milgram test positive was shown on the physical examination, were fully recovered and lived normal daily life without admission by Meridian Tendino-musculature acupuncture and release therapy within 3 to 5, 4 to 7 days, respectively, since they had started to get their outpatient treatment. 5. Two patients was troubled with pain induced, by twitching response and acupuncure stimuli, which lasted around acupunctured muscle for about a day after treatment, so they coudn't endure the pain and quitted treatment in spite of Fair condition. conclusion : Meridian Tendino-musculature acupuncture and release therapy was found to be helpful to patients who wish to recover from their back pain induced by acute lumbar sprain as soon as possible, but the treatment actually had some problems to be overcome such as pain during or after the treatment. therefor, in order to make this treatment method more available, we should pay more attention to improving treatment appliance and acupuncture technique.
Journal of Korean Society of Industrial and Systems Engineering
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v.40
no.4
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pp.164-170
/
2017
The CNC machine tool field is showing a growing trend with the recent rapid development of manufacturing industries such as semiconductors, automobiles, medical devices, various inspection and test equipment, mechanical metal processing equipment, aircraft, shipbuilding and electronic equipment. However, small and medium-sized machining companies that use CNC machine tools are experiencing difficulties in increasingly intense competition. Especially, small companies which are receiving orders from 3rd or 4th venders are very difficult in business management. In recent years, company S experienced difficulty to make product quality and delivery time due to the ignorance of the processing method when manufacturing cooling plate jig made of SUS304 material used for cell phone liquid crystal glass processing. In order to solve these problems, we redesigned the process according to the size of our company and tried to manage all processes with quantified data. In the meantime, we have found that there is a need to improve the cutter process, which accounts for most of the machining process. Therefore, we have investigated the correlation between RPM and FEED of three cutters that have been used in the past. As a result, we found that it is the most urgent problem to solve the roughing process during the cutter operation which occupies more than 70% of the total machining. In order to shorten the machining time and improve the quality in machining of SUS304 cooling plate jig, we select the main factors such as price, tool life, maintenance cost, productivity, quality, RPM, and FEED and use AHP to find the most suitable milling cutter. We also tried to solve the problem of delivery, quality and production capacity which was a big problem of S company through experiment operation with selected cutter tool. As a result, the following conclusions were drawn. First, the most efficient of the three cutters currently available in the machining center has proven to be an M-cutter. Second, although one additional facility was required, it was possible to produce the existing facilities without additional investment by supplementing the lack of production capacity due to productivity improvement. Third, the Company's difficulties in delivery and capacity shortfalls have been resolved. Fourth, annual sales increased by KRW 109 million and profits increased by KRW 32 million annually. Fifth, it can confirm the usefulness of AHP method in corporate decision making and it can be utilized in various facility investment and process improvement in the future.
Kim, Hyeong-Seok;Cho, In-Woo;Shin, Hyun-Seung;Park, Jung-Chul
Journal of Dental Rehabilitation and Applied Science
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v.32
no.3
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pp.176-183
/
2016
Purpose: Patients usually suffer from pain and discomfort after oral surgery and their consumption of food is severely affected. Accordingly, the patients' quality of life reduce significantly. The aim of this study was to analyze patient satisfaction on the nutritional supplement drinks following periodontal surgery. Materials and Methods: Total 90 patients who underwent periodontal surgery were recruited and commercially available nutritional drinks were provided. Group I received two bottles per each meal for 2 days, Group II had one bottle per each meal for 3 days, and Group III had no drinks. The survey for the patient-reported outcome measures (PROMs) were given at the next visit for the removal of sutures. Results: The result of PROMs showed the nutrition drink was easy to intake, appeared to help the healing and can be a satisfying supplement for the meals. Conclusion: Nutritional drinks appeared to help the healing after periodontal surgeries and supported the food intake. Also, it was helpful for the patients in nutritional supply and psychological stability.
Journal of Korean Home Economics Education Association
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v.20
no.2
/
pp.1-14
/
2008
This study was performed to evaluate the effect of the e-Learning application on the teaching learning method in Technology-Home Economics of Middle School. For e-Learning of clothing part, diverse teaching programs and contents were reconstructed and provided in cyber-space. Among the uploaded diverse materials including advanced and supplementary materials, students could make a choice which depends on their own levels. Since the results of assignments could be uploaded in cyber-space and easily accessible to all students, the reliablity of estimation was increased and self-directed learning ability was improved. Also, more effective teaching learning activity could be expected through the mutual exchange of opinion between students and teacher, and among students. Besides, counselling and advices on overall aspect of student's life were also possible. The students were generally satisfied to e-Learning instruction. The interest and understanding about clothing part were increased, and the academic attitude and habit were positively changed. Also they responded that e-Learning instruction were very helpful because learning was possible even after school, diverse materials for learning were available, and submitting the results of assignments was very convenient. In conclusion, the application of e-Learning on the teaching learning method was very effective and should be encouraged. The development and supplement of diverse programs and contents will be necessary for more successful e-Learning instructions.
Korean Journal of Construction Engineering and Management
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v.13
no.5
/
pp.3-11
/
2012
The most of domestic bridge has an used life under 30 years, Future maintenance budgets can be expected to increase. However, because of bridge maintenance budgets are limited, demand for asset management being performed to achieve required performance within available budget is increasing. To perform effective asset management of bridges should be made the best use of information to occur in all phase of construction project. Therefore, the development of system and DB is required to support asset management by effective information management. The objective of this study is the development of the BIM-based bridge asset management model. Through previous research survey, BIM capabilities and asset management components were established and mutual linkages were examined. Bridge asset management model was composed of alternate assessment model. In addition, BIM-based asset management model was performed case studies to verify feasibility and applicability. The proposed model can be applied to a current bridge maintenance procedures and supported to perform effective bridge maintenance tasks within a limited budget.
Kim, Kyung-Ah;Jang, Su-Kil;Cheon, Kyeong-Sik;Seo, Won-Bok;Yoo, Ki-Oug
Korean Journal of Plant Taxonomy
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v.40
no.3
/
pp.135-144
/
2010
This study intended to investigate environmental factors including soil and vegetation in order to understand the environmental and ecological characteristics of four different habitats of Abelia tyaihyoni. These habitats, according to investigations, are mostly located at elevations of 203 m to 297 m with angles of inclination ranging from 9 degrees to 17 degrees. The litter depth of habitats is 2 cm to 5 cm. A total of 113 vascular plant taxa are identified in seven quadrates of the four habitats. The life form of 113 species is H-$D_4$-$R_5$-e type. The importance value of Abelia tyaihyoni is 39.61%, and 4 highly ranked species such as Quercus dentata (6.27%), Spiraea blumei, Spiraea prunifolia for. simpliciflora (4.04%) and Ulmus davidiana var. japonica (3.84%) are considered to be an affinity with Abelia tyaihyoni in their habitats. The dominant species of woody plants in the four habitats are represented as Pinus densiflora (21.22%) and Quercus dentata (16.82%) in the subtree layer (T2), and Carex humilis var. nana (18.95%) and Carex lanceolata (17.63%) in the herbaceous layer (H). The degree of their average species diversity is 1.42, and that of dominance and evenness are 0.07 and 0.86, respectively. The type of soil is sandy loam, clay loam and loam, and the average field capacity of soil is 22.49%. Their average organic matter is 9.39%, soil pH 6.75, and available phosphorus is $1.23 {\mu}g/g$.
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