• 제목/요약/키워드: autograft

검색결과 185건 처리시간 0.021초

Matched Comparison of Fusion Rates between Hydroxyapatite Demineralized Bone Matrix and Autograft in Lumbar Interbody Fusion

  • Kim, Dae Hwan;Lee, Nam;Shin, Dong Ah;Yi, Seong;Kim, Keung Nyun;Ha, Yoon
    • Journal of Korean Neurosurgical Society
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    • 제59권4호
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    • pp.363-367
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    • 2016
  • Objective : To compare the fusion rate of a hydroxyapatite demineralized bone matrix (DBM) with post-laminectomy acquired autograft in lumbar interbody fusion surgery and to evaluate the correlation between fusion rate and clinical outcome. Methods : From January 2013 to April 2014, 98 patients underwent lumbar interbody fusion surgery with hydroxyapatite DBM (HA-DBM group) in our institute. Of those patients, 65 received complete CT scans for 12 months postoperatively in order to evaluate fusion status. For comparison with autograft, we selected another 65 patients who underwent lumbar interbody fusion surgery with post-laminectomy acquired autograft (Autograft group) during the same period. Both fusion material groups were matched in terms of age, sex, body mass index (BMI), and bone mineral density (BMD). To evaluate the clinical outcomes, we analyzed the results of visual analogue scale (VAS), Oswestry Disability Index (ODI), and Short Form Health Survey (SF-36). Results : We reviewed the CT scans of 149 fusion levels in 130 patients (HA-DBM group, 75 levels/65 patients; Autograft group, 74 levels/65 patients). Age, sex, BMI, and BMD were not significantly different between the groups (p=0.528, p=0.848, p=0.527, and p=0.610, respectively). The HA-DBM group showed 39 of 75 fused levels (52%), and the Autograft group showed 46 of 74 fused levels (62.2%). This difference was not statistically significant (p=0.21). In the HA-DBM group, older age and low BMD were significantly associated with non-fusion (61.24 vs. 66.68, p=0.027; -1.63 vs. -2.29, p=0.015, respectively). VAS and ODI showed significant improvement after surgery when fusion was successfully achieved in both groups (p=0.004, p=0.002, HA-DBM group; p=0.012, p=0.03, Autograft group). Conclusion : The fusion rates of the hydroxyapatite DBM and Autograft groups were not significantly different. In addition, clinical outcomes were similar between the groups. However, older age and low BMD are risk factors that might induce non-union after surgery with hydroxyapatite DBM.

결합조직 이식술후 이식편의 수축률에 관한 임상적 연구 (The Clinical Study on Shrinkage Rate of Graft Following Connective Tissue Autografts)

  • 김영준;임성빈;정진형
    • Journal of Periodontal and Implant Science
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    • 제30권3호
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    • pp.639-650
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    • 2000
  • The purpose of this study was to evaluate clinical changes in graft size after treatment with connective tissue autograft in human. 40 premolar teeth in 23 patients having the following mucogingival problemswere selected. The width of extension, attached gingiva including free marginal gingiva, width of transplant and clinical sulcus depth were measured at the initial examination, 2, 12 and 24 weeks following the connective tissue autograft and free gingival autograft. The change of width of extension, attached gingiva including free marginal gingiva, width of transplant and clinical sulcus depth according to healing process in both graft procedures was statistically analyzed by ANOVA test and independent ttest using SPSS program. The results were as follows : 1. The change of keratinized gingiva in both grafting procedures was increased significantly at 24 weeks post-op. 2. The clinical sulcus depth exhibited no marked changes throughoutthe entire investigation in both grafting procedures. 3 . After 12 weeks, no dimensional variation was seen in graft size in both grafting procedures. 4. Shrinkage differs significantly in both grafting procedures. From the day of graft to 24 weeks after surgery the percentages of shrinkage were connective tissue autograft 55% and free gingival autograft 29%.

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신생돈을 이용한 이식 자가 폐동맥의 성장에 관한 연구, 제1보, 수술의 적합성 (Growth of Pulmonary Autograft in Swine, I.Feasibility of the Operation)

  • 안재호
    • Journal of Chest Surgery
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    • 제28권10호
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    • pp.885-891
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    • 1995
  • In order to test the hypothesis that the pulmonic valve, when used to replace the aortic root as a pulmonary autograft, will remain a viable anatomical structure and will grow and develop normally along with the host, we performed aortic valve replacement with the pulmonary autograft in 15 neonatal piglets. The weight of the donor was 9.3 $\pm$ 0.2 kg, the recipient 9.6 $\pm$ 0.3 kg. Measured diameters of pulmonic annulus were 14 $\pm$ 0.2 mm for autograft and 14.2 $\pm$ 0.2 mm for pulmonary artery homograft. Operation was performed under cardiopulmonary bypass with deep hypothermia [20oC at low flow perfusion [70 ml/kg/min . The mean operation time was 227 $\pm$ 10 min., bypass time 152$\pm$ 7.6 min. and aortic cross clamp time 73$\pm$ 4.6 min.. 9 piglets survived more than 12 hours. One survived 12 days and died of pneumonia and the latest one survived in good condition and sacrificed at postoperative 6th week for cardiac catheterization and pathologic examination that revealed the viability and growing of the pulmonary autograft. Currently we are able to complete the operation with good preservation of cardiac function, and our postoperative care has evolved to the extent that we are now confident enough of having an acceptable percentage of long term survivors to undertake a definite study in this regard.

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Strip 치은자가이식술후 이식편의 수축률에 관한 임상적 연구 (The Clinical Study on ShrinKage Rate of Graft following Strip Gingival Autografts)

  • 정해수;임성빈;정진형
    • Journal of Periodontal and Implant Science
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    • 제27권3호
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    • pp.549-559
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    • 1997
  • The purpose of this study was to evaluate clinical changes in graft size after treatment with strip gingival autograft in human. 57 premolar teeth in 27 patients having the following mucogingival problems were selected. The width of extension, attached gingiva including free marginal gingiva, width of transplant and clinical sulcus depth were measured at the initial examination, 2, 12 and 24 weeks following the strip gingival autograft and free gingival autograft. The change of width of extension, attached gingiva including free marginal gingiva, width of transplant and clinical sulcus depth according to healing process in both graft procedures was statistically analyzed by repeated measure ANOVA test and independent t-test using SPSS program. The results were as follows : 1. The change of keratinized gingiva in both graft procedures was increased significantly at 24 weeks post-op. 2. The clinical sulcus depth exhibited no marked changes throughout the entire investigation in both graft procedures. 3. No dimensional variation was seen in graft size in both graft procedures. 4. Shrinkage did not differ significantly in both graft procedures. From the day of grafting to 24 weeks after surgery the percentages of shrinkage were : strip gingival autograft 28% and free gingival autograft 29%.

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자가 슬건을 이용한 재건술: 장점, 단점, 슬건의 재생 (Anterior Cruciate Ligament Reconstruction Using Hamstring Tendon Autograft : Advantage, Disadvantage, Hamstring Regeneration)

  • 김진구;최정윤
    • 대한관절경학회지
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    • 제14권2호
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    • pp.92-101
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    • 2010
  • 전방십자인대 재건술에 자가 슬건과 자가 슬개건이 널리 사용되고 있으나 최근 자가 슬건의 사용이 증가하고 있다. 그 이유는 높은 최대 인장 강도, 낮은 공여부 이환률, 이식건의 고정 방법의 발전과 같은 장점 때문으로 보인다. 전방십자인대 재건술을 위해 슬건을 채취 후 슬건이 실제로 재생된다는 연구는 이러한 이론적 장점을 크게 부각시켰다. 그러나 내 회전력의 약화와 굴곡력의 감소와 같은 단점에 대한 우려가 있다. 이러한 굴곡력의 감소에 대해서 논쟁이 있으며, 과연 슬건의 재생 후에 굴곡력을 회복할 수 있는지에 대해 연구가 필요하다. 본 종설에서는 자가슬건의 장점과 단점, 슬건의 재생에 관한 최근의 연구를 고찰하고 저자들의 연구와 경험을 정리하여 기존의 연구와 비교하였다.

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군날개 재발에 있어서 자가윤부결막이식술 단독 및 추가 윤부절개술의 장기 결과 (Long-term Outcomes of Conjunctivo-limbal Autograft Alone and Additional Widening of Limbal Incision in Recurrent Pterygia)

  • 정인권;김진형;이종현;이도형
    • 대한안과학회지
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    • 제59권12호
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    • pp.1114-1121
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    • 2018
  • 목적: 군날개 수술에서 자가윤부결막이식술 시 재발을 억제하기 위하여 시행한 추가 윤부절개술의 임상성적을 보고하고자 한다. 대상과 방법: 총 95안의 원발성군날개와 12안의 재발성 군날개 환자를 대상으로 자가윤부결막이식술 단독 및 추가 윤부절개술을 시행한 두 군으로 나누어 후향적 분석을 시행하였다. 추가 윤부절개술은 군날개를 제거한 각막윤부의 상부 및 하부경계에 각각 1 mm의 추가 절개를 하는 방법으로 시행하였다. 결과는 자가윤부결막이식술 단독 시행 39안, 추가 윤부절개술 시행 68안을 대상으로 비교 분석하였다. 결과: 전체 환자의 술 후 경과관찰 기간은 $29.6{\pm}10.5$개월이었으며, 자가윤부결막이식술 단독 시행 군에서는 $27.4{\pm}11.5$개월, 추가 윤부절개술 군에서는 $30.7{\pm}9.7$개월이었다. 재발은 자가윤부결막이식술 단독 시행 군에서는 6안(15.4%; 원발성 4안, 재발성 2안)이 있었으며, 추가 윤부절개술 군에서는 2안(2.9%; 원발성 1안, 재발성 1안)을 나타내었고, 두 군 간에 통계적으로 유의한 차이를 보였다(p<0.05). 재발이 나타날 때까지의 평균 기간은 자가윤부결막이식술 단독 시행 군에서 원발성 군날개인 경우 $6.3{\pm}3.4$개월, 재발성군날개인 경우 $4.3{\pm}2.5$개월이었으며, 추가 윤부절개술 군에서는 원발성 $12.1{\pm}2.6$개월, 재발성 $8.4{\pm}4.6$개월을 나타내었고, 두 군 간 통계적으로 유의한 차이를 보였다(p<0.05). 결론: 추가 윤부절개술은 자가윤부결막이식술을 단독 시행하였을 때보다 원발성 및 재발성 군날개 모두에서 재발 방지에 유용한 수술법이다.

Mitral Valve Replacement with a Pulmonary Autograft in an Infant

  • Jeong, Yong Ho;Yun, Tae-Jin
    • Journal of Chest Surgery
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    • 제51권2호
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    • pp.149-152
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    • 2018
  • A 76-day-old infant weighing 3.4 kg was referred for surgical intervention for severe mitral valve stenoinsufficiency caused by leaflet fibrosis and calcification. He had ex perienced a cerebral infarction in the left middle cerebral artery territory, which was deemed attributable to an embolism of a calcified particle from the dysmorphic mitral valve. Because mitral valve replacement using a prosthetic valve was not feasible in this small baby, mitral valve replacement with a pulmonary autograft was performed. After a brief period of extracorporeal membrane oxygenation (ECMO) support, he was weaned from ECMO and was discharged home without further cardiovascular complications.

전경골건 부분 이식을 이용한 장족무지신건 퇴행성 파열의 치료 사례 (Spontaneous Degenerative Rupture of Extensor Hallucis Longus Treated with a Split Tibialis Anterior Tendon Autograft: A Case Report)

  • 김지연;김갑래;김태호
    • 대한족부족관절학회지
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    • 제26권4호
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    • pp.192-195
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    • 2022
  • Chronic extensor hallucis longus (EHL) tendon rupture is relatively rare, but in such cases, surgical repair is necessary to prevent hallux dysfunction. To the best of our knowledge, reconstruction of chronic EHL rupture using a split tibialis anterior tendon autograft has not been previously reported. Here we present a case of spontaneous EHL tendon rupture with a 5 cm gap in a healthy 57-year-old woman. At the 1-year follow-up evaluation, hallux function was restored, and the patient was well satisfied with results.

자가 슬괵건과 동종 전경골건을 이용한 전방 십자 인대 재건술의 임상적 결과 비교 (Comparison of Clinical Results in Anterior Cruciate Ligament Reconstruction Using Hamstring Tendon Autograft and Tibialis Anterior Tendon Allograft)

  • 이희영;최철준;최종혁
    • 대한정형외과스포츠의학회지
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    • 제8권2호
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    • pp.109-114
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    • 2009
  • 목적: 자가 슬괵건과 동종 전경골건을 이용한 전방 십자 인대 재건술의 결과를 비교하고자 한다. 대상 및 방법: 2006년 1월부터 2007년 6월까지 자가 슬괵건과 동종 전경골건을 이용하여 전방 십자 인대 재건술을 시행 받은 환자 중 최소 24개월 이상 추시가 가능하였던 68예를 대상으로 하였다. 36예는 동종 전경골건을 이용하였고 32예는 자가 슬괵건을 이용하였다. 수술 전과 최종 추시 시 이학적 검사, Telos 기구와 KT-2000 arthrometer를 이용하여 두 군을 비교하였고, 주관적 평가로 Lysholm 점수를 사용하였다. 결과: 이식물의 평균 두께는 동종 전경골건에서 9.1(8.0~10.0)mm였으며, 자가 슬괵건에서는 8.0(7.0~9.0)mm였다. 모든 예에서 135도 이상의 관절 운동 범위를 보였으며, 합병증은 관찰되지 않았고 재수술을 요한 경우도 없었다. 수술 전과 최종 추시에서 Telos 스트레스 방사선 검사상에서 환측과 건측의 전방 전위 차이는 동종 전경골건 군은 평균 $7.4{\pm}1.2$ mm에서 $2.3{\pm}1.3$ mm로, 자가 슬괵건 군은 $7.3{\pm}1.0$ mm에서 $2.4{\pm}1.1$ mm로, 두 군 모두 통계적으로 유의하게 향상되었으며(p=0.000), 두 군 간 차이는 없었다(p=0.569). Lysholm 슬관절 점수는 동종 전경골건 군은 $72.3{\pm}3.5$점에서 $91.6{\pm}3.3$점으로, 자가 슬괵건 군은 $72.6{\pm}3.4$점에서 $92.3{\pm}3.5$점으로, 두 군 모두에서 통계적으로 유의하게 향상되었고(p=0.000), 두 군 사이에 차이는 없었다(p=0.425). 결론: 동종 전경골건과 자가 슬괵건을 이용한 전방 십자 인대 재건술 모두 양호한 임상적 결과를 얻었으며, 두 군 사이에 유의한 차이는 없었다. 동종 전경골건과 자가 슬괵건 모두 전방 십자 인대 재건술의 적절한 이식물로 고려될 수 있을 것으로 사료된다.

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