• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10345-10350
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• 2015

Background: Punica granatum (family: Lythraceae) is mainly found in Iran, which is considered to be its primary centre of origin. Studies on pomegranate peel have revealed antioxidant, anti-inflammatory, anti-angiogenesis activities, with prevention of premature aging and reducing inflammation. In addition to this it is also useful in treating various diseases like diabetes, maintaining blood pressure and treatment of neoplasms such as prostate and breast cancer. Objectives: In this study we identified anti-cancer targets of active compounds like corilagin (tannins), quercetin (flavonoids) and pseudopelletierine (alkaloids) present in pomegranate peel by employing dual reverse screening and binding analysis. Materials and Methods: The potent targets of the pomegranate peel were annotated by the PharmMapper and ReverseScreen 3D, then compared with targets identified from different Bioassay databases (NPACT and HIT's). Docking was then further employed using AutoDock pyrx and validated through discovery studio for studying molecular interactions. Results: A number of potent anti-cancerous targets were attained from the PharmMapper server according to their fit score and from ReverseScreen 3D server according to decreasing 3D scores. Conclusion: The identified targets now need to be further validated through in vitro and in vivo studies.

• Journal of Korean Society of Transportation
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• v.33 no.1
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• pp.100-111
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• 2015

After empirically investigating the vehicle accident risks by age groups, various programs and policies have been imposed to reduce the old's risks in other countries. In Korea, it is little known the risk level by age groups and no policy changes has been implemented even if the number of vehicle accidents occurred by the old has been rapidly rising while the total number of vehicle accidents has been decreasing. This study empirically investigates the vehicle accident risks by age groups and the results show that the old drivers over age 65 has the highest accident risk except for the young drivers below age 25. Thus, we emphasize the necessity of reinforcing the qualifications for reissuing the drive licence and programs for educating the old drivers in Korea which is facing the most rapid population aging in the world. On the other hand, various changes are needed reflecting the old drivers such as reforming the road signs, issuing a sticker and providing them incentives such that the old drivers use the public transportation instead of self-driving.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.3
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• pp.1299-1304
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• 2014

This paper is a study for developing an agriculture automatic hose reel of mobile robot. One of the important works in farming is pesticide spraying because it is related to the growth of crops. Therefore, we develop an automatic reel hose and mobile robot. Conducting kinematic analysis of steering performance, the mobile robot is designed to move smoothly even in a small space, and that is verified by simulation. To increase supplying accuracy of the automatic hose reel, the mobile robot use detecting tension mechanism on a hose and a device for the hose deployment. We conduct performance and on-farm evaluation. This system has been maximum speed of 2.5m/s, driving accuracy of ${\pm}0.18^{\circ}$ and driving safety speed of 2m/s. The system would solve an aging population and shortage of workforce in agriculture.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.53 no.3
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• pp.256-265
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• 2017

Seafood is attracting attention as a future food industry. In recent years, the demand for fishery equipment of mechanization, automation, and unmanned was increased due to the environment affected by seafood processing, stricter regulations on safety, decline and aging of fishery worker. Ark shell (Scapharca subcrenata) was being produced in many steps in the production process. The process has been made such as collection-landing-washing-first sort (goods/non-goods)-transports-second sort (size). It was undergone first and second steps by delivering to the consumer. Here, the first step is to sort goods to collection and the second step is to sort by size. The fishery workers need ten people in first step and six people in second step. The workload of one hour per kg is 4,247 kg/h in first step and 2,213 kg/h in second step. In addition, the goods ratio by work process was 79% in first step and 98% in the second step. In this process, a lot of fishery worker and working time is needed. Therefore, this study developed elemental techniques for an automated size sorting system considering the working process problem, time and situation for washing and sorting of ark shell.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.6
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• pp.1373-1378
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• 2018

In order to solve the problems such as reduction of agriculture population, aging and declining of grain self sufficiency rate, agriculture ICT convergence technology utilizing IoT technology is actively being developed. Agricultural ICT technology only concentrates on facility houses, and there is no automated control system in the field of cultivation. In this paper, we propose an irrigation control system that automatically controls the solenoid valves and water pumps in a large area with Lora wireless communication. The proposed system does not require a separate power source by using a small solar panel, and it is very convenient to install and operate supporting wireless auto setup by plug-and-play method. Therefore, it is expected that it will contribute to the reduction of labor force, quality of agricultural products, and productivity improvement.

• The Journal of the Korea Contents Association
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• v.19 no.6
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• pp.160-167
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• 2019

This study was conducted to investigate the effect of initial ripening condition placed within a kimchi refrigerator and this result will be used as basic data for the development of fermentation system of Kimchi refrigerator. Hardness significantly decreased as the storage period longer. Lactic acid and Lactobacillus spp. showed a large amount until 8 weeks, but one without initial ripening contained much lower. The content of lactic acid bacteria increased from 4.50 logCFU/mL to 6.70 ~ 7.47 logCFU/mL and decreased to 5.08 ~ 6.10 logCFU/mL according to storage period. Consumer preferred $15^{\circ}C/52h$ samples rather than others in two weeks. $15^{\circ}C/36h$ and $6^{\circ}C/113h$ samples were significantly preferred during the whole storage period. These results indicate that the initial fermentation conditions affect the taste and fermentation degree of kimchi during the storage period.

• The Journal of Advanced Prosthodontics
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• v.16 no.2
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• pp.115-125
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• 2024

PURPOSE. The purpose of this in vitro study was to investigate the fracture resistance, surface hardness, and color stain of 3D printed, CAD-CAM milled, and conventional interim materials. MATERIALS AND METHODS. A total of 80 specimens were fabricated from auto polymerizing polymethyl methacrylate (PMMA), bis-acryl composite resin, CAD-CAM polymethyl methacrylate resin (milled), and 3D printed composite resin (printed) (n = 20). Forty of them were crown-shaped, on which fracture strength test was performed (n = 10). The others were disc-shaped specimens (10 mm × 2 mm) and divided into two groups for surface hardness and color stainability tests before and after thermal cycling in coffee solution (n = 10). Color parameters were measured with a spectrophotometer before and after each storage period, and color differences (CIEDE2000 [DE00]) were calculated. The distribution of variables was measured with the Kolmogorov Smirnov test, and one-way analysis of variance (ANOVA), Tukey HSD, Kruskal-Wallis, Mann-Whitney U tests were used in the analysis of quantitative independent data. Paired sample t-test was used in the analysis of dependent quantitative data (P < .05). RESULTS. The highest crown fracture resistance values were determined for the 3D printed composite resin (P < .05), and the lowest were observed in the bis-acryl composite resin (P < .05). Before and after thermal cycling, increase in mean hardness values were observed only in 3D printed composite resin (P < .05) and the highest ΔE₀₀ value were observed in PMMA resin for all materials (P < .05). CONCLUSION. 3D printing and CAD-CAM milled interim materials showed better fracture strength. After the coffee thermal cycle, the highest surface hardness value was again found in 3D printing and CAD-CAM milled interim samples and the color change of the bis-acryl resin-based samples and the additive production technique was higher than the PMMA resin and CAD-CAM milled resin samples.

• Journal of Korean Clinical Health Science
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• v.5 no.1
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• pp.808-815
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• 2017

Purpose. To analyze the refractive status between urban and rural regions, of children in Korea, in the age group of 13. Methods. From October 2016 to January 2017, forty subjects( 20 male subjects, 20 female subjects; 13 years) were performed in refraction test using the Auto-Refraction. Myopia, hyperopia, astigmatism, and anisometropia were defined as spherical equivalent(SE)${\leq}-0.50$ diopters, SE ${\geq}+1.00D$, cylinder error ${\geq}0.75D$ and SE difference${\geq}1.00D$ between binocular eyes, respectively. Results. The refractive error by spherical equivalent among all subjects was myopia 76.25%, astigmatism 35%, emmetropia 16.25%, anisometropia 8.75%, and hyperopia 5%. The prevalence of myopia and astigmatism were much more common in urban than rural region although the difference was not statically significant. Emmetropia and astigmatism were much more common in rural region than urban although the difference was not statically significant. The prevalence of spherical equivalent was much common from -1.00 diopter to -4.00 diopter. On the other hand, the prevalence of myopia was much more than hyperopia. There was a statistical significance between OD and OS of rural region in the spherical equivalent power(p<.000). Also, There was a statistical significance between OD and OS of urban region in the spherical equivalent power(p<.004). Therefore, there was a significant statistical similarity between urban and rural regions on the OD and OS in the spherical equivalent power. On the other hand, There was a significant statistical similarity between urban and rural regions of the OD and OS in the astigmatism power(p<0.000). However, in the rural and urban regions there was not statistical significance in the OD and OS concerning the spherical equivalent power and astigmatism power (p>0.1). Conclusions. Myopia was the most common refractive error in Korea young children. while hyperopia was few. There was not a statistical significance as age between rural and urban at spherical equivalent power( P> 0.01). These results suggested that the analysis of the refractive status at young children can give the useful diagnosis data for the correction of visual acuity.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.11
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• pp.851-860
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• 2020

With an increase in the aging population and a rising social interest in health and welfare, studies to improve healthcare in the elderly are being actively conducted. This study attempted to improve the current design and manufacture of elevating electric wheelchairs to enhance user safety and convenience. Seat design based on the user's body shape, convenience while boarding or alighting, caster turning radius and, safety and stability features that prevent shaking when the user gets up or sits down were improved. A driving experiment was conducted to evaluate the operation of the indoor electric wheelchair designed and manufactured with these additional functionalities. During the test, the performance parameters evaluated were continuous driving time, turning radius, maximum lifting and lowering load, maximum lifting height, noise level, minimum distance sensing by the driving auxiliary sensor, ability to interact with server and app programs, and the duty cycle maximum error rate. The test confirmed that this improved electric wheelchair successfully met target parameters. In a future study, we will evaluate this improved electric wheelchair from a user's perspective for its usability parameters, such as satisfaction, convenience and stability.

• Safety and Health at Work
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• v.14 no.4
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• pp.406-414
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• 2023

Background: This study examined age-group differences in the rate, severity, and cost of injuries among construction workers to support evidence-based worker safety and health interventions in the construction industry. Methods: Ohio workers' compensation claims for construction workers were used to estimate claim rates and costs by age group. We analyzed claims data auto-coded into five event/exposure categories: transportation incidents; slips, trips, and falls (STFs); exposure to harmful substances and environments; contact with objects and equipment (COB); overexertion and bodily reaction. American Community Survey data were used to determine the percentage of workers in each age group. Results: From 2007-2017, among 72,416 accepted injury claims for ~166,000 construction full-time equivalent (FTE) per year, nearly half were caused by COB, followed by STFs (20%) and overexertion (20%). Claim rates related to COB and exposure to harmful substances and environments were highest among those 18-24 years old, with claim rates of 313.5 and 25.9 per 10,000 FTE, respectively. STFs increased with age, with the highest claim rates for those 55-64 years old (94.2 claims per 10,000 FTE). Overexertion claim rates increased and then declined with age, with the highest claim rate for those 35-44 years old (87.3 per 10,000 FTE). While younger workers had higher injury rates, older workers had higher proportions of lost-time claims and higher costs per claim. The total cost per FTE was highest for those 45-54 years old ($1,122 per FTE). Conclusion: The variation in rates of injury types by age suggests that age-specific prevention strategies may be useful.