• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제30권1호
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• pp.19-26
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• 2024

Purpose: Autism spectrum disorder impacts children's social, sensory, and language development, necessitating specialized educational support. Special classrooms play a crucial role in providing an appropriate learning environment for children with autism. However, there is a lack of systematic research on creating effective environments in these special classrooms. Methods: This study aims to gain a comprehensive and systematic understanding of the environmental composition of special classrooms for children with autism spectrum disorder, using the following systematic methodologies including literature review and case study. Results: Sensory spaces in special classrooms for children with autism help regulate sensory stimuli and promote sensory development. They provide stability, reducing stress from excessive stimuli, and enhance emotional stability. These spaces also promote communication and interaction among children and expand the diversity of learning activities, enriching experiences and stimulating interest in learning. Implications: Based on the results, we propose suggestions for improving the environment of special classrooms for children with autism spectrum disorder and provide direction for the design of such environments.

• 대한감각통합치료학회지
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• 제17권1호
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• pp.30-42
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• 2019

목적 : 본 연구는 자해행동을 보이는 자폐스펙트럼장애의 비약물적 치료 중심으로 실시한 연구를 대상으로 체계적으로 분석하여 작업치료 임상현장에서 동일한 문제를 보이는 자폐스펙트럼장애 아동에게 적절한 서비스를 제공하기 위한 근거를 마련하고자 한다. 연구방법 : 전자데이터 베이스인 PubMed, Medline, DBpia, RISS, KISS, NDSL을 사용하여 2008년 10월부터 2018년 11월까지 국내외 학회지에 게재된 연구를 대상으로 검색하였다. 주요 용어는"(Autism OR Autism Spectrum Disorder) AND (Therapy OR Treatment OR Intervention) AND (Self Injurious Behavior)"으로 검색하였고, PICO형식과 근거수준을 사용해 분석하였다. 연구결과 : 총 12편의 논문이 선정되었고, 근거의 질적 수준은 대상연구 논문 12편 중 수준 IV와 수준 V가 가장 많았으며, 실험설계는 단일대상연구가 많았다. 중재의 종류는 행동치료가 가장 많았다. 분석결과 자폐스펙트럼장애의 자해행동은 행동치료와 뇌자극 및 조절기법, 행동치료와 병행한 감각통합치료로 자해행동을 감소시켰으며 통계적으로도 유의한 결과를 보였다. 결론 : 자해행동을 보이는 자폐스펙트럼 장애 아동에게 적용한 비약물적 중재에 대한 근거자료를 제시하였다. 앞으로 자폐스펙트럼 장애 아동의 자해행동에 대한 중재효과성을 증명하기 위하여 근거수준이 높은 연구 설계와 다양한 비약물적 중재간의 차이점을 밝히는 연구가 지속적으로 이루어져야 할 것이다.

• Clinical and Experimental Pediatrics
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• 제64권10호
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• pp.538-542
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• 2021

Background: The relationship between small for gestational age (SGA) and autism spectrum disorders (ASDs) remains unknown. Purpose: This meta-analysis aimed to investigate the relationship between SGA and the risk of ASD. Methods: We searched PubMed, Web of Science, and Scopus databases from inception to November 2020. The heterogeneity across studies was explored using the I² statistic. The possibility of publication bias was assessed using Begg test. The results were reported using the odds ratio (OR) and 95% confidence interval (CI) using a random-effects model. Results: The literature search yielded 824 articles with 8,752,138 participants. We assessed the association between SGA and the risk of ASD in cohort and case-control studies. Based on the random-effects model, compared with SGA, the estimated OR of the risk of ASD was 1.17 (95% CI, 1.09-1.24). Therefore, there was a significant association between SGA and the risk of ASD. Conclusion: Based on OR reports in epidemiological studies, we showed that SGA is a risk factor for and can increase the risk of ASD. The association between SGA and ASD risk has further relevance to the current public health emphasis on appropriate prepregnancy weight and pregnancy weight gain.

• International Journal of Computer Science & Network Security
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• 제22권11호
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• pp.149-156
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• 2022

The study aimed to identify the effectiveness of the training program based on the social story strategy for developing self-determination skills among students with autism spectrum disorder. The population of the study consisted of all students with autism spectrum disorder in the Desired Hope Association for People with Disabilities in Makkah Al-Mukarramah and the sample of the study consisted of (6) students. The study used the quasi-experimental approach with one group. To achieve the objectives of the study, the ARCS scale for self-determination skills was used, Hassan Al-Masry (2018). The results of the study revealed, through comparing the students' performances in their pre and post-tests regarding to the ARKS scale and through their answers on the scale, the effectiveness of the training program based on the social story for developing the skills of self-determination among students with autism spectrum disorder. The results also showed that there were statistically significant differences after applying the program when significance level was (0.001). The result came in favor of the post-test.

• The Korean Journal of Physiology and Pharmacology
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• 제16권6호
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• pp.369-378
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• 2012

Analysis of synaptic plasticity together with behavioral and molecular studies have become a popular approach to model autism spectrum disorders in order to gain insight into the pathosphysiological mechanisms and to find therapeutic targets. Abnormalities of specific types of synaptic plasticity have been revealed in numerous genetically modified mice that have molecular construct validity to human autism spectrum disorders. Constrained by the feasibility of technique, the common regions analyzed in most studies are hippocampus and visual cortex. The relevance of the synaptic defects in these regions to the behavioral abnormalities of autistic like behaviors is still a subject of debate. Because the exact regions or circuits responsible for the core features of autistic behaviors in humans are still poorly understood, investigation using region-specific conditional mutant mice may help to provide the insight into the neuroanatomical basis of autism in the future.

• 대한한방소아과학회지
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• 제31권4호
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• pp.49-60
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• 2017

Objectives The purpose of this study is to report the effectiveness of Korean medicine on treating autism spectrum disorder (ASD) in childhood. Methods We treated an 8-years-old patient who was diagnosed with autism (grade II) with herbal medicine, acupuncture and electric moxibustion. Every 11 months, Korean-Childhood Autism Rating Scale (K-CARS) was used to assess the patient's symptom progression. Results After 21 months of Korean medicine treatment, the child's overall health was improved. Moreover, language ability, emotional control, memory and cognitive abilities got better, as well as anxiety, agitation, and aggressive behavior related to ASD were also decreased. K-CARS score at the initial stage of the treatment was 39.5 points, which can be considered as severe autism. After 11 months of the treatment, the K-CARS score was 34.5 points which is mild-moderate autism. Conclusions Korean medicine treatment can be effective in improving symptoms of ASD. However, further studies are needed to demonstrate the treatment benefits to ASD.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제34권2호
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• pp.117-124
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• 2023

Savant syndrome was described before autism. However, they soon became closely associated, as many of their symptoms (intellectual disability, repetitive behaviors, alterations in social communication, and islets of abilities) overlap. Only a few women with autism have been diagnosed with savant syndrome. The theories or hypotheses that attempt to explain savant syndrome, which are common in autism, present differential treatment according to sex. We postulate that savant syndrome associated with autism as well as autism in general is underdiagnosed in women.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제25권2호
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• pp.95-96
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• 2014

• 한국콘텐츠학회논문지
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• 제11권8호
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• pp.221-230
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• 2011

이 연구는 요인분석을 통해 아동 청소년 행동평가척도(Korean-Child Behavior Checklist: K-CBCL)가 자폐 범주성 장애 아동의 정서와 행동적 문제를 평가하는 도구로 타당한지를 알아보기 위해 실시되었다. 이를 위해 자폐 범주성 장애 아동 248명을 대상으로 K-CBCL을 측정하고 요인분석을 실시하였다. 확인하고자 하는 요인 모델은 2요인 모델로 위축, 신체증상, 불안/우울의 내재화 문제와 비행과 공격성의 외현화 문제였다. 확인적 요인분석 결과, K-CBCL의 2요인 모델의 적합도 지수는 표준화적합지수 .964, 비교 적합지수 .975, 근사오차평균자승이중근은 .091로 나타나 모델의 부합도 기준을 만족하는 것으로 나타났다. 확인적 요인분석을 통해 2요인 모델의 적합성을 확인한 후, 하위 요인들의 문항내적합치도를 알아보았다. 위축, 사회적 미성숙, 비행의 하위 요인의 문항내적합치도는 낮게 나타났으나, 내재화 문제, 외현화 문제, 총 문제행동 척도는 문항내적합치도가 적합한 수준으로 나타났다. K-CBCL은 자폐 범주성 장애 아동의 정서와 행동적 문제를 평가한 도구로 타당한 도구임을 논의하였다.

• 대한한방소아과학회지
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• 제32권2호
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• pp.11-25
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• 2018

Objectives The purpose of this study is to provide evidence of pathogenesis, pattern differentiation, treatment principle, formula of traditional Chinese medicine for autism spectrum disorder by reviewing journal articles published in China. Methods We searched literatures dated up to 8 January, 2018 in China National Knowledge Infrastructure (CNKI), and evaluated pathogenesis, pattern differentiation, treatment principle, formula of traditional Chinese medicine for autism spectrum disorder. Results Thirty four studies were selected for analysis. These studies included pathogenesis, pattern differentiation, treatment principle, formula of traditional Chinese medicine for autism spectrum disorder. The most common pattern differentiations were the pattern of kidney essence depletion, pattern of phlegm confounding the orifices of the heart, pattern of dual vacuity of the heart and spleen, pattern of effulgent heart-liver fire, pattern of liver failing to course freely. The most common treatment principles were supplementing the kidney, transquilizing, fortifying the spleen, transforming phlegm, opening the orifices, and calming the liver. The most commonly-used formulas were Yukmijihwangtang (六味地黃湯), Modified Ondamtang (加味溫膽湯), Guibitang (歸脾湯), Yangsimtang (養心湯), Jwaguihwan (左歸丸), Cheonmagudeungeum (天麻鉤藤飮), and Danchisoyosan (丹梔逍遙散). Conclusions This study shows the latest trend of pathogenesis, pattern differentiation, treatment principle, formula of traditional Chinese medicine for autism spectrum disorder. Further study is needed to solidify these findings.