• Steel and Composite Structures
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• v.29 no.4
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• pp.451-464
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• 2018

This paper presents some quasi-static tests for 4 mixed columns composed of CFST column and RC column. The seismic performance and failure mode were studied under low-cyclic revised loading. The failure mode was observed under different axial compression ratios. The hysteretic curve and skeleton curve were obtained. The effects of axial compression ratio on yield mechanism, displacement ductility, energy dissipation, stiffness and strength attenuation were analyzed. The results indicate that the failure behavior of CFST-RC mixed column with archaized style is mainly caused by bending failure and accompanied by some shear failure. The axial compression ratio performs a control function on the yielding order of the upper and lower columns. The yielding mechanism has a great influence on the ductility and energy dissipation capacity of specimens. Based on the experiment, finite element analysis was made to further research the seismic performance by ABAQUS software. The variable parameters were stiffness ratio of upper and lower columns, axial compression ratio, yielding strength of steel tube, concrete strength and rebar ratio. The simulation results show that with the increase of stiffness ratio of the upper and lower columns, the bearing capacity and ductility of specimens can correspondingly increase. As the axial compression ratio increases, the ductility of the specimen decreases gradually. The other three parameters both have positive effect on the bearing capacity but have negative effect on the ductility. The results can provide reference for the design and engineering application of mixed column consisted of CFST-RC in Chinese archaized buildings.

• Journal of Institute of Control, Robotics and Systems
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• v.10 no.5
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• pp.402-410
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• 2004

To obtain a good tracking performance in an optical disk drive servo system, it is essential to attenuate periodic disturbances caused by eccentric rotation of the disk. As an effective control scheme for enhancing disturbance attenuation performance, disturbance observers (DOBs) have been successfully applied to the track-following servo system of optical disk drives. In disk drive systems, the improvement of data transfer rate has been achieved mainly by the increase of disk rotational speed, which leads to the increase of the disturbance frequency. Conventional DOBs are no longer effective in disk drive systems with a high-speed rotation mechanism because the performance of conventional DOBs is severely degraded as the disk rotational frequency increases. This paper proposes a new DOB structure for effective rejection of the disturbance in optical disk drives with a very high rotation speed. Asymptotic disturbance rejection is achieved by adopting a band-pass filter in the DOB structure, which is tuned based on the information on the disturbance frequency. In addition, performance sensitivity of the proposed DOB to changes in disk rotational frequency is analyzed. The effectiveness of the proposed DOB is verified through simulations and experiments using a DVD-ROM drive.

• Proceedings of the Korean Society of Plant Pathology Conference
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• 2003.10a
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• pp.144.1-144
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• 2003

Attenuated viruses can protect their hosts against challenge to their related viruses. Increasing evidence shows that mutations of the tobamoviral 126/183 kDa protein play a major role in the viral attenuation and contribute to the cross protection mechanism. In this study, four mutants of Pepper mild mottle virus (PMMoV) have been constructed by mutagenesis; two mutants, pTPpoly348 and pTPpoly762, were substituted in the middle of replicase gene, and the others, pTPL3D:: $\Delta$6207 and pTPL3D:: $\Delta$6219, were deletion mutants made by deleting some parts of pseudoknot structures of the 3' noncoding region (NCR) of the virus. Progeny viruses generated from the four mutants were infectious on N. benthamiana plants with symptomless or mild mosaic symptom. Replication efficiency and viral product accumulations of four mutants were assessed by Northern and Western blot analyses on BY-2 protoplast cells. Accumulation of CP for the pTPL3D:: $\Delta$6207 and pTPL3D:: $\Delta$6219 were lower than that of other mutants and wild type virus. These data suggest that the 3'-NCR mutations contribute to the viral gene expression in host tissues, while mutants of replicase gene rather govern the symptom expression.

• The Korean Journal of Physiology and Pharmacology
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• v.3 no.6
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• pp.579-586
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• 1999

Complement-mediated neutrophil activation has been hypothesized to be an important mechanism of reperfusion injury. It has been proposed that C1 esterase inhibitor (C1 INH) may prevent the complement- dependent activation of polymorphonuclear leukocytes (PMNs) that occurs within postischemic myocardium. Therefore, The effect of C1 INH was examined in neutrophil dependent isolated perfused rat heart model of ischemia (I) (20 min) and reperfusion (R) (45 min). Administration of C1 INH (5 mg/Kg) to I/R hearts in the presence of PMNs $(100{\times}10^6)$ and homologous plasma improved coronary flow and preserved cardiac contractile function (p＜0.001) in comparison to those I/R hearts receiving only vehicle. In addition, C1 INH significantly (p＜0.001) reduced PMN accumulation in the ischemic myocardium as evidenced by an attenuation in myeloperoxidase activity. These findings demonstrate the C1 INH is a potent and effective cardioprotective agent inhibits leukocyte-endothelial interaction and preserves cardiac contractile function and coronary perfusion following myocardial ischemia and reperfusion.

• Journal of Institute of Control, Robotics and Systems
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• v.6 no.10
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• pp.871-880
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• 2000

A twin-servo mechanism is used to increase the payload capacity and assembling speed of high precision motion control systems such as semiconductor chip mounters. In this paper, we focus on the modeling of the twin-servo system and propose its network representation. And also, we propose a robust synchronizing motion control algorithm to cancel out the skew motion of the twin-servo system caused by different dynamic characteristics of two driving systems and the vibration generated by high accelerating and decelerating motions. The proposed control algorithm consists of separate feedback motion control algorithms for each driving system and a skew motion compensation algorithm. A robust tracking controller based on internal-loop compensation is proposed as a separate motion controller and its disturbance attenuation property is shown. The skew motion compensation algorithm is also designed to maintain the synchronizing motion during high speed operation, and the stability of the whole closed loop system is proved based on passivity theory. Finally, experimental results are shown to illustrate control performance.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.18 no.1
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• pp.67-73
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• 1988

This study was performed to clarify the mechanism of clicking sound and locking on temporomandibular joint and to determine the radiographic findings of them by using computed tomogram. Through the preliminary study with cadavers, the proper scanning condition and the correlatonship between the anatomy of cadaver and computed tomogram had been determined. The subjects were consisted of 10 controls and 16 patients having clicking sound or locking on temporomandibular joint. By using Hitachi-W500 as computed tomographic device, direct axial views and sagittal views reformed according to the changes in window setting and using the non-linear fraction were taken and analyzed by visual method and measuring the attenuation numbers. The obtained results were as follows: 1. The density of the anterior band of meniscus showed isodense to the surrounding muscles in normal. 2. In patient group, affected side showed increased radiopaque area anterior to condyle and underneath articular eminence as the feature of anteriorly displaced meniscus on axial and sagittal views. 3. In patient group, the condyle was rotated postero-laterally in affected side. 4. Non-linear fraction highlightened the feature of anteriorly displaced meniscus.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.16 no.7 s.112
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• pp.754-761
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• 2006

This paper presents the dynamic characteristics of MR impact damper for vehicle collision system. Various types of mechanism have been proposed to reduce force transmitted to the vehicle chassis and finally to protect occupants from injury. In the case of head-on collision, the bumper makes main role of isolation material for collision attenuation. In this study, the proposed bumper system consists of MR impact damper and structures. The MR impact damper utilizes MR fluid which has reversible properties with applied magnetic field. The MR fluid operates under flow mode. The bellows is used for generation of fluid flow. A mathematical model of the MR impact damper is derived incorporating with Bingham model of the MR fluid. Field dependent damping force is investigated with time and frequency domain. The MR impact damper is then incorporated with vehicle crash system. The governing equation of motion of vehicle model is formulated considering occupant model. Dynamic characteristics of vehicle collision system investigated with computer simulation.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2011.10a
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• pp.843-848
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• 2011

Planning and construction of railway for high speed trains up to 400 km/h are recently driven in Korea. High speed train is one of the environment-friendly fastest mass transportation means but its noise generated by rolling, traction and aerodynamic mechanism can cause public complaints of residents nearby railways. To cost-effectively prevent the troublesome noise in a railway planning stage, the rational railway noise prediction method considering the characteristics of trains as well as railway structures should be required but it is difficult to find authentic methods for Korean high speed trains such as KTX and KTX-II. In this study, we propose a framework of our own railway noise prediction model emitted by Korean high speed trains over 250 km/h based on the recent research results carried out in EU countries. The model considers railway sound power level using several point sources distributed in heights as well as tracks, whose detail speed- and frequency-dependent emission characteristics of Korean high speed trains should be determined in near future by measurement or numerical analysis. The attenuation during propagation outdoors is calculated by the well-known ISO 9613-2 and auxiliary methods to consider undulated terrain and wind effect.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2006.05a
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• pp.147-152
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• 2006

This paper presents the dynamic characteristics of MR impact damper for vehicle collision system. Various types of mechanism have been proposed for reduce transmitted force to vehicle chassis and finally protect occupants from injury. In the case of frontal collision, the bumper make main role of isolation material for collision attenuation. In this study, proposed bumper system composed of MR impact damper and structures. The MR impact damper is to adopted MR fluid which has reversible properties with applied magnetic field. MR fluid operates under flow mode with Bingham flow and bellows is used for generation of fluid flow. Mathematical model of MR impact damper incorporated with MR fluid is established. Field dependent damping force is investigated with time and frequency domain. The MR impact damper is then incorporated with vehicle crash system. The governing equation of motion of vehicle model is formulated considering occupant model. Dynamic characteristics of vehicle collision system investigated with computer simulation.

• Clinical and Experimental Reproductive Medicine
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• v.42 no.1
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• pp.1-7
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• 2015

Stress coping mechanisms are critical to minimize or overcome damage caused by ever changing environmental conditions. They are designed to promote cell survival. The unfolded protein response (UPR) pathway is mobilized in response to the accumulation of unfolded proteins, ultimately in order to regain endoplasmic reticulum (ER) homeostasis. Various elements of coping responses to ER stress including Perk, Ask1, Bip, Chop, Gadd34, Ire1, Atf4, Atf6, and Xbp1 have been identified and were found to be inducible in oocytes and preimplantation embryos, suggesting that, as a normal part of the cellular adaptive mechanism, these coping responses, including the UPR, play a pivotal role in the development of preimplantation embryos. As such, the UPR-associated molecules and pathways may become useful markers for the potential diagnosis of stress conditions for preimplantation embryos. After implantation, ER stress-induced coping responses become physiologically important for a normal decidual response, placentation, and early organogenesis. Attenuation of ER stress coping responses by tauroursodeoxycholate and salubrinal was effective for prevention of cell death of cultured embryos. Further elucidation of new and relevant ER stress coping responses in periimplantation embryos might contribute to a comprehensive understanding of the regulation of normal development of embryonic development and potentiation of embryonic development in vitro.