• Title/Summary/Keyword: atagonistic effect

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Analysis on characteristics of antagonistic stiffness of the planar 3 degrees-of-freedom RCC mechanism (평면형 3 자유도 RCC 메카니즘의 상반효과로 인한 강성 특성 분석)

  • 이병주;김희국;이준용
    • 제어로봇시스템학회:학술대회논문집
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    • 1996.10b
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    • pp.718-721
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    • 1996

  • In this work, an effective stiffness generated by internal loading for a planar 3 degrees of freedom RCC mechanism is investigated. For this purpose, the internal kinematic analysis and antagonistic stiffness modeling for this mechanism are performed. It is shown that the antagonistic stiffness could be effectively created at the center of the mechanism in its symmetric configuration.

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Anti-Tumor Effect of Cyclophosphamide, TUbercin-3 , and Picibanil on Sarcoma-180 Bearing Mice (Sarcoma-180 유발 생쥐에 대한 Cyclophosphamide, Picibanil 및 Tubercin-3의 투여효과)

  • Lee, In-Seon;Kim, Hyuk-Il;Whang, Key
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.23 no.6
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    • pp.922-926
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    • 1994

  • This study was carried out to detemrine the efficacy of combined treatment of cyclophosphamide with tubericin-3 and or picibanil. One hundred sixty sarcoma-180 bearing mice were divided eight groups. Each group received saline, tubercin-3, picibanil , and cyclophosphamide along and/or received cyclophosphamide with tubercin-3 , with picibanil or with both tubercin-3 and picinanil, respectively.Average surviving time of each group of animals was as follows ; control was 10.9days, tubercin-3 was 15.1 days. picibanil was 12.6 days, and cylophosphamide was 17.9 days, In combined therapyy that cylophosphamide injected with tubercin-3 , the surviving time was 26.8 days an din the case of other therapy that cyclophosphamide injected with tubercin-3, the surviving time was 26.8 days an din the case of other therapy that cyclophosphamide injected with picibanil, the surviving time was 21.9 day and cyclophosphamide treated with both turbercin03 and picibanil, the surviving time was found to be 18.2 days, conclusively , the therapeutic potentiation seemed to be extended when combined tretment of the chemotherapeutics cyclophosphamide with either one of immunotherapeutics tubericin-3 or picibanil was tried, Combinatin of tubercin-3 and picibanil showed to be atagonistic each other. Yield of ascites fluid were determined 7 days after injectino of sarcoma-180 ascites tumor cells. Adminitration of cyclophosphamide, tubercin-3 , and picibanil alone and their various combinations reduced the yield of ascites fluid except for picibanil group.

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