• Maxillofacial Plastic and Reconstructive Surgery
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• 제42권
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• pp.31.1-31.7
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• 2020

Background: Fibrous dysplasia (FD) is a rare, sporadic, and benign congenital condition in which normal cancellous bone is replaced by fibro-osseous tissue with immature osteogenesis. FD localized in the cranial and facial bones is called craniofacial fibrous dysplasia (CFD). Cystic degeneration in CFD cases is rare; cystic degeneration appearing in both the maxilla and the mandible FD lesion is even rarer. The aim of this article was to report a case of fibrous dysplasia of the mandible and maxilla complicated by nonspecific cystic degeneration. Case presentation: A 30-year-old woman presented with a rare case of non-specific cystic degeneration in a mandible and maxilla FD lesion that occurred 11 years after surgery. She was diagnosed with polyostotic CFD and underwent maxillary and mandibular bone contouring. Cyst enucleation under general anesthesia was performed in the mandibular region due to pain and discomfort. Conclusions: In cases involving non-aggressive and non-invasive FD cystic degeneration in focal areas, conservative treatment is recommended. However, if cystic degeneration of FD develops rapidly and causes discomfort, pain, or dysfunction, surgical treatment should be considered.

• 한국과학예술포럼
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• 제37권3호
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• pp.113-123
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• 2019

본 연구는 영상콘텐츠 산업과 과학문화 산업의 지형 변화에서 시작되었다. 모바일 과학기술 영상 콘텐츠는 수요와 정책적 지원에 따라 성장 가능성이 예견된다. 본 연구의 목적은 과학기술 관련 모바일 영상콘텐츠 활성화를 위해 현황을 분석하여 기획 및 제작시의 시사점을 제시하는 것이다. 따라서 본 논문은 모바일 영상 중 영향력이 가장 큰 유튜브의 과학기술 채널의 영상을 사례로 하여 유형 및 스토리텔링 분석을 시도하는 융복합적 연구를 진행하였다. 연구결과 및 내용은 다음과 같다. 첫째, 과학기술 유튜브 채널 글로벌 선도그룹의 영상 콘텐츠는 과학기술의 맥락과 활동에 따라 활동형, 해설형, 비평형의 세 유형으로 범주화된다. 둘째, 언어의존성이 낮고 재매개 가능성이 높은 활동형 채널은 다시 라이프 해킹형, 소품 제작형, 파괴형, 탐구형으로 분류된다. 셋째, 활동형 채널들의 핵심 스토리텔링 전략은 일상적 소재를 전문과학기술적 방법을 통해 다루는 익숙함과 낯섦의 조화이다. 이러한 연구결과를 바탕으로 국제적 경쟁력을 가질 수 있는 킬러 콘텐츠 기획 및 제작을 기대한다.

• 한국노년학
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• 제30권1호
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• pp.159-177
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• 2010

본 연구의 목적은 고령화현상에 따른 노인부양 문제에 초점을 맞추고 부양활동의 보완재 혹은 도구로써 Information Technology (IT)의 활용을 제안하며, 이의 실행가능성 파악에 있다. 조사방법으로 예비와 현재 노인부양자 대상의 Focus Group Interview (FGI)를 실시하여 부양활동에 대한 부양자들의 의견 및 욕구를 탐색적으로 조사하고, 노인부양활동에 실질적으로 도움이 되는 IT의 역할을 파악하고자 하였다. 조사결과 노인부양자는 노인을 부양할 때 시간과 장소의 제한 없이 노인의 건강, 안전, 위치를 확인하길 바라며, 이러한 욕구는 유비쿼터스 속성을 가진 IT의 부양활동 보완역할을 통해 충족이 가능한 것으로 나타났다. FGI 결과를 기반으로 본 연구는 노인부양문제 해결을 위한 IT의 활용 및 보완 방안을 보다 구체적으로 제언하여 IT의 부양활동 보완역할의 가능성을 긍정적으로 보았다. 결론적으로 IT는 기존 부양서비스와 접목되어 부양활동을 지원하고 보완하여 부양자의 부양부담을 감소시켜주는 역할에 초점이 맞춰져야 하며, 무조건적인 IT 적용 및 기술 강조는 오히려 부작용을 가져올 수 있음을 강조하였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제45권5호
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• pp.241-253
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• 2019

This study evaluated and compared the donor site morbidity following minimally invasive and conventional open harvesting of iliac bone for secondary alveolar bone grafting in cleft palate patients. A thorough electronic search of PubMed, Google Scholar, EMBASE, and an institutional library and manual search of various journals was done; Inclusion criteria: 1) full-text articles using a minimally invasive or conventional open harvesting technique for iliac bone for secondary alveolar grafting in cleft palate patients and 2) articles published between January 1, 2001 and June 30, 2017 and Exclusion criteria: 1) articles published in languages other than English, 2) case reports, case series, animal studies, in vitro studies, and letters to the editor, and 3) full-text article unavailable even after writing to the authors. Preliminary screening of 274 studies excluded 223 studies for not meeting the eligibility criteria. Of the remaining 51 studies, 19 were removed for being duplicates. Of the remaining 32 studies, 15 were excluded after reading the abstract. Of the 17 studies that were left, 2 were excluded because they were in a language other than English, and 2 were excluded because the study group did not mention cleft palate patients. Thus, 13 studies providing results for a total of 654 patients were included in this qualitative synthesis. Minimally invasive bone graft harvest techniques are better than the conventional open iliac bone harvest method because they offer shorter operative time, decreased requirement for pain medications, less pain on discharge, and a shorter hospital stay.

• International Journal of Computer Science & Network Security
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• 제21권3호
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• pp.21-30
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• 2021

Economic transformations have led to an increase in the role of creative assets and their central role in public life. Changes in creative activity have led to a change in the organization of the work of institutes engaged in the training of specialists, in particular teachers of labor education. Methods and approaches to training determine the development of creative industries, being the basis for models of professional training of future teachers of labor training. The purpose of an article was to develop a modern model of professional training of future teachers of labor training based on the concept of creative economy. The methodology is based on the concepts of holistic craft and creative economy. Based on the integration of pedagogical learning models "Craft as design and problem-solving", "Craft as skill and knowledge building", "Craft as product-making" and "Craft as self-expression" developed and experimentally confirmed the conceptual model of professional training of future teachers of labor training. The proposed model forms a practitioner with professional, technical, digital and creative skills who is able to transfer the experience to students. The training course "Creativity and creative thinking" has been developed. The model provided for the development of a course based on the strategy of developing professional creativity, flexibility, improvisation, openness, student activity, joint practice, student-oriented approach. The practical value implies the adaptation of the developed model of professional training of future teachers of labor education during the training of teachers in higher education, which is confirmed in the experiment.

• 대한간호학회지
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• 제51권4호
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• pp.442-453
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• 2021

Purpose: This study was conducted to assess public awareness and policy challenges faced by practicing nurses. Methods: After collecting nurse-related news articles published before and after 'the Thanks to You Challenge' campaign (between December 31, 2019, and July 15, 2020), keywords were extracted via preprocessing. A three-step method keyword analysis, latent Dirichlet allocation topic modeling, and keyword network analysis was used to examine the text and the structure of the selected news articles. Results: Top 30 keywords with similar occurrences were collected before and after the campaign. The five dominant topics before the campaign were: pandemic, infection of medical staff, local transmission, medical resources, and return of overseas Koreans. After the campaign, the topics 'infection of medical staff' and 'return of overseas Koreans' disappeared, but 'the Thanks to You Challenge' emerged as a dominant topic. A keyword network analysis revealed that the word of nurse was linked with keywords like thanks and campaign, through the word of sacrifice. These words formed interrelated domains of 'the Thanks to You Challenge' topic. Conclusion: The findings of this study can provide useful information for understanding various issues and social perspectives on COVID-19 nursing. The major themes of news reports lagged behind the real problems faced by nurses in COVID-19 crisis. While the press tends to focus on heroism and whole society, issues and policies mutually beneficial to public and nursing need to be further explored and enhanced by nurses.

• BMB Reports
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• 제54권12호
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• pp.592-600
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• 2021

Parkinson's disease (PD) is one of the most common neurodegenerative diseases in the elderly population and is caused by the loss of dopaminergic neurons. PD has been predominantly attributed to mitochondrial dysfunction. The structural alteration of α-synuclein triggers toxic oligomer formation in the neurons, which greatly contributes to PD. In this article, we discuss the role of several familial PD-related proteins, such as α-synuclein, DJ-1, LRRK2, PINK1, and parkin in mitophagy, which entails a selective degradation of mitochondria via autophagy. Defective changes in mitochondrial dynamics and their biochemical and functional interaction induce the formation of toxic α-synuclein-containing protein aggregates in PD. In addition, these gene products play an essential role in ubiquitin proteasome system (UPS)-mediated proteolysis as well as mitophagy. Interestingly, a few deubiquitinating enzymes (DUBs) additionally modulate these two pathways negatively or positively. Based on these findings, we summarize the close relationship between several DUBs and the precise modulation of mitophagy. For example, the USP8, USP10, and USP15, among many DUBs are reported to specifically regulate the K48- or K63-linked de-ubiquitination reactions of several target proteins associated with the mitophagic process, in turn upregulating the mitophagy and protecting neuronal cells from α-synuclein-derived toxicity. In contrast, USP30 inhibits mitophagy by opposing parkin-mediated ubiquitination of target proteins. Furthermore, the association between these changes and PD pathogenesis will be discussed. Taken together, although the functional roles of several PD-related genes have yet to be fully understood, they are substantially associated with mitochondrial quality control as well as UPS. Therefore, a better understanding of their relationship provides valuable therapeutic clues for appropriate management strategies.

• International Journal of Computer Science & Network Security
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• 제21권7호
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• pp.257-266
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• 2021

This article examines the features of improving the public management of the market of medical and social services using information technology to improve the efficiency of public activity in modern conditions. The interpretation of the essence of the categories "information technologies" and "information support" is analyzed. The importance of the organization of information support of public authorities in the insurance of the state apparatus of information management for the adoption and solution of state issues of the market of medical and social services has been studied. Issues and system of information support of public management of the market of medical and social services are considered. The stages of the ICT implementation process in the market of medical and social services are described. The tools of state regulation in the market of medical and social services and the introduction of targeted programs for the development of the social sphere and health care are highlighted. Recommendations for improvement are formulated public management of the market of medical services and social way introduction of ICT tools, which provide for the implementation of a set of measures aimed at intellectualizing the entire system public data management spheres. The necessity of development of innovative tools of public management of the market of medical and social services of Ukraine for the purpose of working out of strategies of increase of quality of medical and social services in the XXI century is substantiated. A number of benefits from the implementation of an effective process of application of information support of public management of the market of medical and social services to ensure the efficiency of public authorities of Ukraine. It is proposed to create a "Department of information support of self-government" and electronic health care system (e-Health) to improve the management decision-making process, which will provide an opportunity to accumulate, process, analyze, and as a result, get the expected effect in the form of balanced management decisions by public authorities of Ukraine.

• 이베로아메리카
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• 제22권1호
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• pp.1-30
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• 2020

최근 라틴아메리카의 우경화 과정에서 보수적인 오순절교회의 정치 참여가 크게 부각되고 있다. 이 글은 브라질 사례를 중심으로, 이러한 정치 참여가 민주주의와 그 발전에 끼치는 영향에 주목한다. 먼저 오순절교회들은 성장과 확산을 통해 가톨릭 중심의 독점적 구도를 무너뜨리고 종교적 다원화에 크게 기여했지만, 자신과 다른 종교나 이념에 대한 배타적이고 공격적 태도를 보인다, 또한 주요한 참여 형태인 공식 후보와 관련하여 지도부의 일방적인 결정에 다수의 신자들은 정치적으로 동원되고, 이렇게 당선된 후보자는 공익보다는 지도부의 지도하에 자신의 교단 또는 교회의 특수한 조합주의적 이해관계에 복무한다. 그리고 국회의원, 주의원 등 공직을 획득하려는 정치 참여의 목적도 그리스도교 왕국 재건이라는 특수한 종교적 이해나 가치의 직접적인 실현에 둠으로써 브라질의 민주주의 발전에 걸림돌로 작용한다.

• Archives of Plastic Surgery
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• 제50권3호
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• pp.315-324
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• 2023

Hemoglobinopathies such as sickle cell disease (SCD) are traditionally considered a relative contraindication to free tissue transfer, due to concerns that erythrocyte sickling will increase the risk of microvascular thrombosis and flap failure. This article describes a case report with the successful use of free tissue transfer in a patient with SCD and provides a systematic literature review on free tissue transfer in SCD. A retrospective chart review was performed of a patient with SCD who underwent free tissue transfer at the authors' institution. A systematic literature review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines was performed using the keywords "free tissue transfer," "free flap," or "microsurgery" and "sickle cell" on PubMed, Ovid/Medline, and Scopus. A 29-year-old male with delayed presentation of an electrical burn to the face and scalp underwent wound closure with a free anterolateral thigh flap. Key management principles included red blood cell transfusion to keep hemoglobin S under 30% and hemoglobin greater than 10 g/dL, maintenance of hydration, normothermia, adequate analgesia, and postoperative anticoagulation. Systematic literature review identified 7 articles describing 13 cases of free tissue transfer in 10 patients with SCD, with combined complete free flap success in 10 of the 13 flaps. Free tissue transfer can be successfully performed in patients with SCD. However, evidence on the optimal management of this unique patient population in the perioperative period after free tissue transfer is limited to case reports in the literature.