• Title/Summary/Keyword: arthritis

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Differences in Illness Intrusivenss between Rheumatoid Arthritis and Osteoarthritis (골관절염 환자와 류마티스 관절염 환자의 지각된 질병 영향 비교)

  • Kim, In-Ja;Kim, Jong-Im;Lee, Eun-Ok
    • Journal of muscle and joint health
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    • v.10 no.2
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    • pp.119-130
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    • 2003
  • Illness intrusiveness(illness induced lifestyle disruption) was investigated in 902 patients with arthritis and compared between rheumatoid arthritis(N=439) and osteoarthritis(N=463) patients. Arthritis patients were reported to perceive illness intrusiveness similar to patients with ESRD(end stage renal disease), bipolar disorder and peritoneal dialysis. Especially they were intrusive into health, work, and active recreation domains. And patients with rheumatoid arthritis were significantly more intrusive into activities, especially in diet, financial situation, family relations, other social relations, self-expression/self improvement, religious expression, and community and civic involvement. Differences in treatment regimens and age were hypothesized to account for these differences in illness intrusiveness.

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Candida tropicalis arthritis of the elbow in a patient with Ewing's sarcoma that successfully responded to itraconazole

  • Kim, Seung-Youn;Lim, Jung-Sub;Kim, Dong-Hwan;Lee, Hyeon-Jeong;Cho, Joong-Bum;Lee, Jun-Ah;Kim, Dong-Ho
    • Clinical and Experimental Pediatrics
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    • v.54 no.9
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    • pp.385-388
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    • 2011
  • Fungal infections are rarely responsible for arthritis. Few cases of fungal arthritis have been reported, even in immunocompromised hosts susceptible to low-virulence organisms. Herein, the authors report the first case of Candida tropicalis arthritis in a child with a solid tumor. A 13-year-old boy with Ewing's sarcoma developed arthritis in his elbow during the neutropenic period after chemotherapy. Despite treatment with broad-spectrum antibiotics, his condition did not improve and serial blood cultures failed to reveal any causative organisms. After surgical drainage, culture of the joint fluid revealed the presence of C. tropicalis. Itraconazole treatment was started and after 3 months of therapy, the patient completely recovered full elbow function.

Arthroscopic Treatment for Septic Arthritis of the Shoulders in Neonates: A Case Report

  • Park, Kyoung-Jin;Lee, Hyung-Ki
    • Clinics in Shoulder and Elbow
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    • v.19 no.3
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    • pp.163-167
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    • 2016
  • Septic arthritis in neonates is a rare condition. A failure to make an early diagnosis of septic arthritis in neonates may leave a permanent disability as a result of a delayed treatment. Thus, septic arthritis, requires a prompt diagnosis and a timely treatment especially in this subset of patients. In this case report, we describe our treatment protocol for septic arthritis and concurrent osteomyelitis in the right shoulder of a 28-day-old newborn. Using 2.4 mm wrist arthroscopy, we performed an arthroscopic irrigation and drainage, to remove intra-articular debris and inflammatory tissue, and multiple drilling. We report a satisfactory clinical outcome without any postoperative complications or side effects.

Influencing Factor on Social Support perceived by Patients with Rheumatoid Arthritis (류마티스 관절염 환자가 지각하는 사회적 지지와 영향요인에 관한 조사연구)

  • Yoo, Kyung Hee
    • Journal of muscle and joint health
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    • v.21 no.2
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    • pp.145-152
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    • 2014
  • Purpose: The purpose of this study was to investigate the influencing factors on the social support perceived by patients with rheumatoid arthritis. Methods: The subjects for this study were 468 patients registered in 2 general hospitals and the period of data collection was from October 20, 2013 to February 20, 2014. The data were analyzed with t-test, ANOVA and Pearson's correlation coefficients. Results: The mean of item of social support was 3.31 in patients. For social support, there were significant differences by gender and economics in patients with rheumatoid arthritis. Conclusion: Managing social support was important for patients with rheumatoid arthritis to promote health. To enhance social support of patients with rheumatoid arthritis, nursing intervention strategies must be developed for increasing economics or giving information about their activity of daily living.

The Clinical Study on the Effect of Acupotomy on Chronic Arthritis of Ankle (침도침 시술을 시행한 만성 족관절 염좌 환자 2례에 대한 증례보고)

  • Kim, Min-Jung;Hong, Kwon-Eui
    • Journal of Acupuncture Research
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    • v.25 no.4
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    • pp.157-162
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    • 2008
  • Objectives : The purpose of this study is to report the effect of acupotomy for patients with chronic arthritis of ankle. Methods : We treated Two patients who have chronic arthritis of ankle with acupotomy. To check the effect and satisfaction of acupotomy we used visual analog scale(VAS) and Five-point Likert scale. At the same time, we measured Change of ankle range of motion(ROM). Results : As a result of evaluation by using VAS, after treatment VAS score decreased(VAS3, VAS5). ROM of ankle widened. And the Likert scale point were checked 3 and 4. Conclusions : This study shows acupotomy has useful effect on chronic arthritis of ankle. An acupotomy is an alternative effective treatment modality for chronic arthritis of ankle.

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Interleukin 17-expressing Innate Synovial Cells Drive K/BxN Serum-induced Arthritis

  • Cho, Wang Sik
    • Proceedings of the Korea Contents Association Conference
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    • 2018.05a
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    • pp.551-552
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    • 2018
  • K/BxN serum can induce arthritis in normal mice because of abundant autoantibodies that trigger an innate inflammatory response in joints. To determine whether IL-17 is involved in the pathogenesis of serum-induced arthritis, we injected wild-type and $IL-17^{-/-}$ mice with K/BxN serum and evaluated them for signs of arthritis. Unlike wild-type mice, $IL-17^{-/-}$ mice did not show any signs of arthritis. IL-17 was produced predominantly by $CD3^-CD4^-gdTCR^-NK1.1^-Sca1^{int}Thy1^{hi}$ cells residing in the inflamed synovial tissue. When synovial cells extracted from normal joints were stimulated with IL-23 or autoantibody-containing immune complexes, a substantial fraction of $Sca1^{int}Thy1^{hi}$ cells produced IL-17. Thus, we have identified a novel population of IL-17-producing innate synovial cells that play a crucial role in the development of K/BxN serum-induced arthritis.

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Comparison of Ankle Arthrodesis and Total Ankle Arthroplasty in End-Stage Ankle Arthritis (말기 발목 관절염 환자에서 발목 유합술과 발목관절 전치환술의 비교)

  • Young Sik, Yoon;Dong Yeon, Lee
    • Journal of Korean Foot and Ankle Society
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    • v.26 no.4
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    • pp.151-156
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    • 2022
  • The proportion of patients with end-stage ankle arthritis is increasing. The leading surgical methods for treating patients with end-stage ankle arthritis are ankle arthrodesis and total ankle arthroplasty. Ankle arthrodesis is considered the standard treatment for end-stage ankle arthritis. Many studies have been conducted on the two procedures, but it is unclear which is superior, and total ankle arthroplasty cannot be said to be a clear indication. Therefore, this review compares the advantages and disadvantages of two representative surgical methods for treating end-stage ankle arthritis.

A Study on the Effect of Aqua-acupuncture with Stephania Tetrandra solution on Arthritis (목방기약침(木防己藥鍼)이 관절염(關節炎)에 미치는 영향(影響))

  • Lee, Yeun-kyung;Lee, Byung-ryul
    • Journal of Acupuncture Research
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    • v.18 no.4
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    • pp.125-142
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    • 2001
  • Objective : The purpose of this study is to observe the effect of Aqua-acupuncture with Stephania Tetrandra Solution (ST-AS) on arthritis. Methods : The author performde several experimental items : that isgene expression and secretion of IL-$1{\beta}$, IL-6, TNF-${\alpha}$, MMP-2, production of ROS, paw thickness, DTH, weight of spleen, expression of CD4+, CD8+, CD19+ in the spleen, production of IL-6, TNF-${\alpha}$, examination of histology. Results : The obstain results are summarized as follows. 1. IL-$1{\beta}$, IL-6, TNF-${\alpha}$ gene expression of hFLS were significantly inhibited in treatmentgroup, and gene expression of MMP-2 was not inhibited in treatmentgroup. 2. The secretion amount of IL-$1{\beta}$, IL-6, TNF-${\alpha}$ were significantly inhibited in treatmentgroup. 3. Expression of P-38 MAP kinase and production of ROS were inhibited in treatmentgroup. 4. Treatmentgroup were significantly inhibited the incidence of arthritis, hind paw edema, the index of arthritis and DTH of CIA (collagen II-induced arthritis) mice. 5. Treatmentgroup were significantly decreased splenetic weight and the number of CD4+, CD8+, CD19+ activated cells and secretion aroout of IL-6, TNF-${\alpha}$ of CIA (collagen II-induced arthritis) mice.. 6. Treatmentgroup were expressed form of new bone, synoviumin, new margine in histology imperison to controlgroup. Conclusions : Taking all these observations into account, ST-AS injection is considered to be effective in treating arthritis and put to practical use in future arthritis clinic.

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The Effects of Tai Chi for Arthritis on Chronic Arthritic Pain of Senior Female : A Pilot Study (만성 관절 통증 여성 노인환자에 있어 관절염 태극권의 효과에 대한 pilot study)

  • Hwang, Eui-Hyoung;Kim, Jung-Hwan;Jang, In-Soo;Yang, Chang-Sop;Kang, Jun-Won
    • Journal of Korean Medicine Rehabilitation
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    • v.20 no.1
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    • pp.79-90
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    • 2010
  • Objectives : Tai Chi for arthritis was developed in 1997 by Paul Lam, M.D. of family medicine in Australia. It is an exercise treatment program and a good approaching method for arthritis. However its application is limited to arthritis of knee joint only. Even there have been no clinical study in korean traditional medical society. The aim of this study is to investigate effect of the Tai Chi for arthritis on chronic pain of body. Methods : We designed this trial as objectives were (1) senior female over 60 years, (2) suffering for osteoarthritis and chronic body pain, (3) have no physical or mental dysfunctions (4) able to walk and exercise alone. Objectives mactched these criteria had been trained the Tai Chi for arthritis 2 hours a day for 21 weeks. Before and after training, pain of 8 joints (neck, shoulder, elbow, wrist, waist, hip, knee, ankle) were estimated with the VAS(Visual Analog Scale). Results : Training the Tai Chi for arthritis relieved multiple joint pain(especially neck, lower back, shoulder, wrist and knee) and these were statistically significant. Conclusions : This study is a pilot study to investigate effect of the Tai Chi for arthritis on chronic pain of whole body. Absence of control group, and other scale to test joint function except VAS were limitations of this study. It is the first clinical approach about Tai Chi in korean medicine field, also the first study of Tai Chi for pain of the whole body.

Effect of Herbal-acupuncture with Chaenomelis Fructus Solution at the Joksamni($ST_{36}$) of Mice with Collagen-induced Aarthritis (목과(木瓜) 약침(藥鍼)이 Collagen-induced Arthritis 억제 및 면역조절에 미치는 영향)

  • Shin, Dong-Soo;Kim, Young-Il;Lee, Hyun
    • Journal of Acupuncture Research
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    • v.24 no.3
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    • pp.127-143
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    • 2007
  • Objectives : The purpose of this study was to observe the effects of Chaenomelis Fructus herbal-acupuncture solution (ChF-HAS) at the Joksamni ($ST_{36}$) on arthritis induced by Collagen II in mice. Methods : The author performed several experimental items. The severity of arthritis, changes of mouse weight, size of the spleen and the degree of stenosis, changes of cytokine level, IgG, IgM and anti-collagen II, changes of immunocyte count, histological changes of the CIA mouse joint were analyzed and the conclusions are as follows. Results: 1. In the ChF-HA, the arthritis index, the incidence of arthritis, the degree of joint edema was significantly decreased. 2. In the ChF-HA, weight, spleen size and stenosis rate was low and maintained as the normal group was. 3. In the ChF-HA, cytokine level, IgG, IgM and anti-collagen II were significantly decreased. 4. In the ChF-HA, on changes of immunocyte count were maintained to the levels of normal group. 5. In histological changes of the CIA mouse joint, the cartilage destruction and synovial cell proliferation were decreased. Conclusions: These results suggest that ChF-HA at the $ST_{36}$ has an important role to control the immune reactions and suppress inflammatory response on the collagen induced rheumatoid arthritis. This study can be a significant supporting evidence that ChF-HA is chosen to be the principal therapy for clinical practice of the rheumatoid arthritis in the future.

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