• Title/Summary/Keyword: area under the curve

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Constitutive Modeling of Confined Concrete under Concentric Loading

  • Lee, Cha-Don;Park, Ki-Bong;Cha, Jun-Sil
    • KCI Concrete Journal
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    • v.13 no.1
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    • pp.69-78
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    • 2001
  • The inelastic behavior of a reinforced concrete columns is influenced by a number of factors : 1) level of axial load, 2) tie spacing, 3) volumetric ratio of lateral steel, 4) concrete strength, 5) distribution of longitudinal steel, 6) strength of lateral steel, 7) cover thickness, 8) configuration of lateral steel, 9) strain gradient, 10) strain rate, 11) the effectively confined concrete core area, and 12) amount of longitudinal steel. A new constitutive model of a confined concrete is suggested in order to investigate the nonlinear behavior of the reinforced concrete columns under concentric loading. The developed constitutive model for the confined concrete takes into account the effects of effectively confined area as well as the horizontal and longitudinal distributions of the confining pressures. None of the existing models incorporated these two main effects at the same time. A total of different six constitutive models for the behavior of the confined concrete under concentric compression were compared with the sixty-one test results reported by different researchers. The superiority of the developed model in its accuracy is demonstrated by evaluating the error function, which compares the weighted averages for the sum of squared relative differences in peak compressive strength and corresponding strain, stress at strain equal to 0.015, and total area under stress-strain curve up to strain equal to 0.015.

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Application of Receiver Operating Characteristic (ROC) Curve for Evaluation of Diagnostic Test Performance (진단검사의 특성 평가를 위한 Receiver Operating Characteristic (ROC) 곡선의 활용)

  • Pak, Son-Il;Oh, Tae-Ho
    • Journal of Veterinary Clinics
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    • v.33 no.2
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    • pp.97-101
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    • 2016
  • In the field of clinical medicine, diagnostic accuracy studies refer to the degree of agreement between the index test and the reference standard for the discriminatory ability to identify a target disorder of interest in a patient. The receiver operating characteristic (ROC) curve offers a graphical display the trade-off between sensitivity and specificity at each cutoff for a diagnostic test and is useful in assigning the best cutoff for clinical use. In this end, the ROC curve analysis is a useful tool for estimating and comparing the accuracy of competing diagnostic tests. This paper reviews briefly the measures of diagnostic accuracy such as sensitivity, specificity, and area under the ROC curve (AUC) that is a summary measure for diagnostic accuracy across the spectrum of test results. In addition, the methods of creating an ROC curve in single diagnostic test with five-category discrete scale for disease classification from healthy individuals, meaningful interpretation of the AUC, and the applications of ROC methodology in clinical medicine to determine the optimal cutoff values have been discussed using a hypothetical example as an illustration.

A PARAMETRIC BOUNDARY OF A PERIOD-2 COMPONENT IN THE DEGREE-3 BIFURCATION SET

  • Kim, Young Ik
    • Journal of the Chungcheong Mathematical Society
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    • v.16 no.2
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    • pp.43-57
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    • 2003
  • The boundary of a typical period-2 component in the degree-3 bifurcation set is formulated by a parametrization of its image which is the unit circle under the multiplier map. Some properties on the geometry of the boundary are investigated including the root point, the cusp and the length as well as the area bounded by the boundary curve. The centroid of the area for the period-2 component was numerically found with high accuracy and compared with its center. An algorithm drawing the boundary curve with Mathematica codes is proposed and its implementation exhibits a good agreement with the analysis presented here.

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Site Attenuations of an Open Area Test Site (야회시험장의 시험장감쇠량)

  • 김기채;정연춘;정정환;정낙삼
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.27 no.9
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    • pp.1336-1343
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    • 1990
  • In this paper the theoretical analysis of the site attenuation was made on the concept of mutual impedance of antennas and the cause of characteristic hump in the site attenuation curve below 80 MHz is explained. The deviation between the FCC site attenuatios and the experimental results of an ideal open area test site at low frequencies(below 80MHz) was found to be the mutual coupling effects of the antennas under the FCC's measurement conditions. It seems desirable that the site attenuations curve of FCC document be revicused to the theoretical curves presented in this paper is long as the FCC's measurement conditions are to the applied.

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VARIOUS CENTROIDS AND SOME CHARACTERIZATIONS OF CATENARY CURVES

  • Bang, Shin-Ok;Kim, Dong-Soo;Yoon, Dae Won
    • Communications of the Korean Mathematical Society
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    • v.33 no.1
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    • pp.237-245
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    • 2018
  • For every interval [a, b], we denote by $({\bar{x}}_A,{\bar{y}}_A)$ and $({\bar{x}}_L,{\bar{y}}_L)$ the geometric centroid of the area under a catenary curve y = k cosh((x-c)/k) defined on this interval and the centroid of the curve itself, respectively. Then, it is well-known that ${\bar{x}}_L={\bar{x}}_A$ and ${\bar{y}}_L=2{\bar{y}}_A$. In this paper, we fix an end point, say 0, and we show that one of ${\bar{x}}_L={\bar{x}}_A$ and ${\bar{y}}_L=2{\bar{y}}_A$ for every interval with an end point 0 characterizes the family of catenaries among nonconstant $C^2$ functions.

The Effect of Tetramethoxyflavone on the Pharmacokinetics of Paclitaxel in Rats (테트라메톡시프라본이 파크리탁셀의 약물동태에 미치는 영향)

  • 나종학;백채선;최준식
    • YAKHAK HOEJI
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    • v.48 no.4
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    • pp.226-230
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    • 2004
  • The pharmacokinetics of orally administered paclitlxel (50 mg/kg) was studied in six rabbits after 1hr pretreatment (2.0 mg/kg and 10 mg/kg) of tetramethoxyflavone or coadministration of (2.0 mg/kg, 10 mg/kg and 20 mg/kg) tetramethoxyflavone. The area under the plasma concentration-tine curve (AUC) and plasma concentration of paclitaxe1 coadministered with tetramethoxyflavone (10 mglkg) were increased significantly (p<0.05) compared with control. However, coadministration of tetramethoxyflavone (2 and 20 mg/kg) showed no significant effect on the pharmacokinetic parameters of paclitaxel. Pretreatment with tetramethoxyflavone significantly (p<0.05) increased the plasma concentration of paclitaxel. The area under the plasma concentration-time curve (AUC) and the peak concentration (C$_{max}$) of paclitaxel pretreated with tetramethoxyflavone were increased significantly (p<0.01, p<0.05) compared with control. The terminal half. life of paclitaxel pretreated with tetramethoxyflavone (2 mg/kg and 10 mg/kg) was significantly (p<0.05) prolonged compared with control. Pretreatment with tetramethoxyflavone (2.0 mg/kg, 10 mg/kg) significantly (p<0.01, p<0.05) increased the absolute bioavailability of paclitaxel compared with the control (154∼179%). On the basis of the results, it might be considered that tetramethoxyflavone may inhibit cytochrome P450 or P-glycoprotein efflux pump which are engaged in paclitaxel metabolism, result in increased AUC and t$_{1}$2/ of paclitaxel. However, further study should be conducted to clarify the roles of cytochrome P450 and P-glycoprotein on paclitaxel bioavailability with/or without tetramethoxyflavone. P-glycoprotein on paclitaxel bioavailability with/or without tetramethoxyflavone.

Experimental Studies on Atomization Characteristics in Diesel Fuel Spray(I) (디젤분무특성에 관한 실험적 연구(I))

  • 박호준;장영준
    • Journal of the korean Society of Automotive Engineers
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    • v.12 no.5
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    • pp.76-84
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    • 1990
  • To study diesel fuel spray behavior, an experimental study was undertaken to investigate injection characteristics in vary ing back pressure and atomization mechanism in a non-evaporating diesel spray. Generally, injection characteristics is the curve of fuel flow plotted against time. The area under this curve is equal to the total quantity of fuel discharged for one injection. The method that measures rate of injection is long tube-type fuel rate indicator. Diesel spray injected into a quiescent gaseous environment under high pressure is observed by taking high speed camera by the focused shadow photographs. The results show that, at the start of injection, as the injected fuel rushes into the quiescent atmosphere the spray angle becomes large. Finally the spray stabilizes at a constant cone angle. Spray penetration length increases with the injection pressure.

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Development of a Korean Geriatric Suicidal Risk Scale (KGSRS) (한국형 노인자살위험 사정도구 개발)

  • Lee, Sang Ju;Kim, Jung Soon
    • Journal of Korean Academy of Nursing
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    • v.46 no.1
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    • pp.59-68
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    • 2016
  • Purpose: Increase in suicide rate for senior citizens which has become widespread in our society today. It is not a normal social phenomenon and is beyond the danger level. The contents of this study include Korean senior citizens' suicide related risk factors and warning signs, and the development of a simple Geriatric Suicide Risk Scale. Methods: This study is Methodological Research to verify reliability and validity of the Geriatric Suicide Risk Scale according to the tool development process suggested by Devellis (2012). Results: For predictive validity assessment, high suicide screening accuracy was showed with an Area under the ROC curve (AUC) of .93. For the optimal cutoff point of 11, sensitivity was 93.9%, and specificity, 75.7% which are excellence levels. Cross validity for assessment of generalization possibility showed the Area under the ROC curve (AUC) as .82 and in case of a cutoff point of 11, sensitivity was 73.7%, and specificity, 65.9%. Conclusion: When it comes to practical nursing, it is significant that the Korean Geriatric Suicide Risk Scale has high reliability and validity through adequate tool development and the tool assessment step to select degree of suicide risk of senior citizens. Also, it can be easily applied and does not take a long time to administer. Further, it can be used by health care personnel or the general public.

Comparative Pharmacokinetics for Dermal Application of a New SYC-fentanyl Patch in Rabbits (토끼에 있어서 SYC-fentanyl패취제의 경피투여 동태비교)

  • 신호철;이영미;최학수;이정훈;유현석;한상섭
    • YAKHAK HOEJI
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    • v.44 no.2
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    • pp.189-192
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    • 2000
  • We examined a dermal pharmacokinetics for a new SYC-fentanyl patch in rabbits. Determination of fentanyl in the plasma was performed using a gas chromatography with nitrogen-phosphorus detection system and a capillary column. One patch per animal (fentanyl 2.5 mg) was applied to clipped back skin for 72 hours. The plasma fentanyl concentration profile of SYC-patch was similar to that of a conventional patch (Durogesi $c^{R}$, Janssen Co.). No significant difference was observed in the pharmacokinetic parameters, the area under the concentration-time curve (AU $C^{0-}$72hrs/) and the total area under the first moment-time curve (AUM $C^{0-}$7hrs/), between the two patch types. The AU $C^{0-}$7hrs/ and AUM $C^{0-}$72hrs/ of durogesi $c^{R}$ were 183.3$\pm$46.28 ng*hr/ml and 6,450$\pm$1,939ng*h$r^2$/ml, and those of SYC-fentany patch were 217.2$\pm$50.51$\pm$ng*hr/ml and 8,022$\pm$2,245ng*h$r^2$/ml, respectively (n=3). This result indicates that the new SYC patch has a similar bioavailability compared to durogesi $c^{R}$ patch. Therefore, the SYC-patch may be considered as a bioequivalent fentanyl patch.patch.tch.

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Study on Improvement of Surface Properties of SKD61 Powder on S45C Using Laser Cladding

  • Cheol-Woo Kim;Hyo-Sang Yoo
    • Archives of Metallurgy and Materials
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    • v.67 no.4
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    • pp.1465-1468
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    • 2022
  • In this study, we investigated the effect of cladding on structural carbon steel (S45C) using 5%Cr-1.5%Mo-Fe powder (SKD61), which is expected to show economically efficient production of die-casting parts. The process conditions were performed under argon atmosphere using a diode laser source with specialized wavelength of 900-1070 nm, and the output conditions were 3, 4, and 5 kW, respectively. After the cladding was completed, the surface coating layer's shape and the microstructure were analyzed. The hardness test was carried out with Micro Vickers hardness tester under 500 gram-force along the normal line at the interval of 0.2 mm from the surface to core direction on the cross-sectional area. In addition, polarization curve test of the surface coating layer was performed to investigate the corrosion resistance characteristics.