• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2000년도 춘계임시총회 및 학술발표대회
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• pp.20-20
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• 2000

• 생약학회지
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• 제48권1호
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• pp.51-55
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• 2017

Aralia continentalis Kitagawa (Araliaceae), known as "Dokwhal" in Korea, has been widely used in traditional Korean medicine for analgesia, neuralgia, sweating, and rheumatism. The biological activity was estimated with methanol extracts of from cultivated roots and adventitious roots of A. continentalis. DPPH and ABTS activities showed the highest activity in methanol extract of adventitious roots at 175.6 and $279.7{\mu}g/mL$ ($RC_{50}$), respectively. Antioxidant activity of methanol extract of the adventitious roots was higher than other samples. In the antibacterial activity assay (paper disc method), the methanol extract of adventitious roots showed activity against S. aureus, S. epidermidis, B. subtilis, and S. enterica. This study demonstrated that adventitious roots of A. continentalis, which was produced for the first time in the roots of A. continentalis, can be used as a natural antioxidant and antibacterial agents.

• Archives of Pharmacal Research
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• 제27권8호
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• pp.825-828
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• 2004

Two triterpenoids (1,4) and two triterpenoid glycosides (2,3) were isolated from the root of Acanthopanax koreanum (Araliaceae). Their structures were identified as impressic acid (1), acankoreoside A (2), 3-epi-betulinic acid 28-O-［(${\alpha}-L-rhamnopyranosyl(1{\rightarrow}4)-{\beta}-D-glucopyrano-syl(1{\rightarrow}6)]-{\beta}-D-glucopyranosyl]$ ester (3), and ursolic acid (4) by physicochemical and spectro-scopic methods. Of these compounds, impressic acid (1) exhibited a potent inhibitory activity against NFAT transcription factor ($IC_{50}:{\;}12.65{\;}{\mu\textrm{m}}$).

• Archives of Pharmacal Research
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• 제27권9호
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• pp.912-914
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• 2004

Seven compounds were isolated from the stem of Acanthopanax senticosus by repeated col-umn chromatography. Their structures were elucidated as isovanillin (1), (-)-sesamin (2), iso-fraxidin (3), (＋)-syringaresinol (4), 5-hydroxymethylfurfural (5), eleutheroside B (6), and eleuth-eroside E (7) by spectral analysis. Among them, isovanillin (1) was isolated for the first time from the family Araliaceae.

• Mycobiology
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• 제38권4호
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• pp.316-320
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• 2010

Leaf spot and blight disease was observed on two-year-old seedlings of Dendropanax morbifera (Korean name: Hwangchil tree) during July of 2008 in Jindo Island, Korea. Symptoms included yellow-brown to dark brown irregularly enlarged spots frequently located along the veins of leaves. The lesions were often surrounded by chlorotic haloes. Severe leaf blight and subsequent defoliation occurred when conditions favored disease outbreak. The causal organism of the disease was identified as Alternaria panax based on morphological characteristics and sequence analysis of the internal transcribed spacer region of rDNA. A. panax isolates induced leaf spots and blight symptoms not only on D. morbifera but also on the other members of Araliaceae tested. This is the first report of foliar blight caused by A. panax on D. morbifera.

• 생약학회지
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• 제34권4호통권135호
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• pp.269-273
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• 2003

The leaves of Acanthopanax sessiliflorus Seem. (Araliaceae), which is native plant to Korea, have not been studied yet on triterpene constituents. Three 3,4-seco-lupane triterpenoids (Compound I-III) were isolated from the MeOH extract of this plant using Diaion HP-20P, silica gel and ODS column chromatographes. Based on physicochemical and spectroscopic data, the chemical structures of these compounds were identified as follows ; chiisanogenin (Compound I), chiisanoside (Compound II), $22{\alpha}-hydroxychiisanoside$ (Compound III).

• Archives of Pharmacal Research
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• 제14권1호
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• pp.19-24
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• 1991

One new triterpenoidal saponin, saponin F(2) has been isolated from the bark of Kalopanax pictum Nakai var. typicum (Araliaceae), together with one known saponin, kizuta saponin $K_{12}$ (1). On the basis of chemico-spectral evidences, the structure of 2 has been elucidated to be 3-O-${\beta}$-D-xylopyranosyl$(1{\rightarrow}3)$-${\alpha}$-L-rhamnopyranosyl$(1{\rightarrow}2)$-${\alpha}$-L-arabinopyranosyl-23-hydroxyolean-12-en-28-O-${\alpha}$-L-rhamnopyranosyl$(1{\rightarrow}4)$-${\beta}$-D-glucopyranosyl$(1{\rightarrow}6)$-${\beta}$-D-glucopyranosyl ester.

• Archives of Pharmacal Research
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• 제14권1호
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• pp.7-11
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• 1991

Three triterpenoid saponins were isolated from the methanol extract of the stem bark of Kalopanax pictum Nakai var. magnificum (Araliaceae). The structures of these saponins were identified as hederagenin 3-O-${\alpha}$-L-arabinopyranoside, hederagenin-3-O-${\alpha}$-L-rhamnopyranosyl$(1{\rightarrow}2)$-${\alpha}$-L-arabinopyranoside and 3-O-${\alpha}$-L-rhamnopyranosyl(1{\rightarrow}2)-${\alpha}$-L-arabinopyranosyl hederagenin 28-O-${\alpha}$-L-rhamnopyranosyl$(1{\rightarrow}4)$-${\beta}$-D-glucopyranosyl$(1{\rightarrow}6)$-${\beta}$-D-glucopyranosyl ester.

• 생약학회지
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• 제39권1호
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• pp.50-55
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• 2008

"Ga Si O Gal Pi" is one of the Korean crude drugs used mainly to cure arthritis, acute gastritis, and beriberi. With regard to the botanical origin of "Ga Si O Gal Pi", it has been considered to be Acanthopanax species of Araliaceae, but there was no pharmacognostical confirmation on it. To clarify the botanical origin of "Ga Si O Gal Pi", the anatomical characteristics of the branch of Acanthopanax species growing wild in Korea and Japan, A. chiisanensis, A. divaricatus, A. koreanum, A. rufinerve, A. senticosus, A. seoulense, A. sessiliflorus, A. sieboldiaum were studied. As a result, it was clarified that "Ga Si O Gal Pi" was the branch and rarely the bark of branch of Acanthopanax senticosus.

• Journal of Ginseng Research
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• 제39권4호
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• pp.287-298
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• 2015

Ginseng, a perennial plant belonging to the genus Panax of the Araliaceae family, is well known for its medicinal properties that help alleviate pathological symptoms, promote health, and prevent potential diseases. Among the active ingredients of ginseng are saponins, most of which are glycosides of triterpenoid aglycones. So far, numerous saponins have been reported as components of Panax ginseng, also known as Korean ginseng. Herein, we summarize available information about 112 saponins related to P. ginseng; >80 of them are isolated from raw or processed ginseng, and the others are acid/base hydrolysates, semisynthetic saponins, or metabolites.