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Effects of aqua-acupuncture with Panax Ginseng on immune response induced by Glucocorticoid in mouse (인삼약침(人蔘藥鍼)이 glucocorticoid투여 Mouse의 면역반응에 미치는 영향)

  • Lee, Eun-Hong;Moon, Jin-Young;Lim, Jong-Kook
    • The Journal of Korean Medicine
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    • v.18 no.1
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    • pp.326-336
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    • 1997
  • In order to investigate the effect of aqua-acupuncture solution with Panax Ginseng into $Qihai(CV_6)$ and $Shenshu(BL_{23})$ on immune response induced by glucocorticoid in mouse, Panax Ginseng aqua-acupuncture solution was injected into $Qihai(CV_6)$ and $Shenshu(BL_{23})$ for seven days after injection with glucocorticoid. And then MA-HRP (methamphetamine-horseradish peroxidase) induced antibody production, numbers and lysozyme activity in macrophage were measured. The results were as follows: 1. The antibody production in mouse immunized with MA-HRP was decreased in control group as compared with normal group. Although $Qihai(CV_6)$ group showed slight increasement, $Shenshu(BL_{23})$ group indicated great increasement compared with normal group. However in Aa-BL group, antibody production was almost increased to normal group. 2. In control group, the numbers of macrophage were decreased about 14% as compared with normal group. And in the pretreated groups of $Qihai(CV_6)$ and $Shenshu(BL_{23})$ were respectively increased 3.0 times and 2.9 times as compared with normal group. 3. Effect of Panax Ginseng-aqua acupuncture solution on the lysozyme activity in macrophage was increased gradually in the pretreated groups of $Qihai(CV_6)$ and $Shenshu(BL_{23})$ as compared with control group. These results suggest that Panax Ginseng aqua-acupuncture at $Qihai(CV_6)$ and $Shenshu(BL_{23})$ may increase antibody production and lysozyme activity in macrophage that is suppressed by glucocorticoid, and Panax Ginseng aqua-acupuncture will have immuno adjuvant effects on the cells which concerned with immunomechanisms.

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The Effects of Progressive Resistive Exercise and Aqua Exercise Program on Lower Extremity Muscle Strength and Balance in Elderly Women. (점진적 저항운동과 수중운동프로그램이 여성노인의 하지근력강화와 균형능력에 미치는 영향)

  • Lee, In-Hak;Moon, Sung-Ki;Lee, Byoung-Kwon;Lee, Jung-Woo;Kim, In-Sup
    • Journal of the Korean Academy of Clinical Electrophysiology
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    • v.2 no.1
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    • pp.19-37
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    • 2004
  • The purpose of this study was to examine the effects of Progressive Resistive Exercise Program and Aqua Exercise Program on Lower extremity Muscle strength, Balance in Elderly old. The average age of elder female was 71.65 years. Subjects of the study were twenty older women living in daejon. The date were analyzed with frequency, independent t-test, paired t-test using SPSS PC(ver.10.0). The subjects were practiced with focusing on the Progressive Resistive Exercise Program and Aqua Exercise Program for 8 weeks, from 8, April 2002 to 1, June 2002. The results of this study were as follows: 1. After the Progressive Resistive Exercise Program, Balance ability by OLSTR, OLSTL was improved(p<0.05) on the soft surface with close eyes. 2. After the Aqua Exercise Program, the strength of the right knee flexors and extensors was improved(p<0.05). 3. After the Aqua Exercise Program, the strength of the left knee flexors was improved(p<0.01). 4. After the Aqua Exercise Program, Balance ability by OLSTR was improved(p<0.001) on the soft surface with open eyes, close eyes and by OLSTL was improved(p<0.05) on the hard surface with open eyes.

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The Clinical Observation of Peripheral facial paralysis used Aqua-acupuncture treatment (자하차(紫河車) 약침(藥鍼)이 말초성안면신경마비(末梢性顔面神經麻痺)에 미치는 영향(影響)에 관(關)한 임상적(臨床的) 고찰(考察))

  • Lee, Jung-hyun;Kim, Yeoung-ho;Yook, Tae-han;Lee, Eun-yong;Kim, Ee-Hwa
    • Journal of Acupuncture Research
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    • v.19 no.1
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    • pp.11-23
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    • 2002
  • Objective : Lately oriental medicine treatment of peripheral facial paralysis is various. In various treatments, this study makes a report that effect of our clinic using aqua-acupuncture with hominis placenta for peripheral facial paralysis. Materials and Methods : This report have been observed among twenty-six patients with peripheral facial paralysis who admitted to oriental medicine hospital with Se-myung university during Jan. 1st, 2001 to Oct. fourth, 2001. These patients were divided into two groups; the first group added aqua-acupuncture with hominis placenta to basic oriental medicine treatment., while the second group was only treated with basic oriental medicine treatment. Results : The results of treatment with adding aqua-acupuncture with hominis placenta to basic oriental medicine treatment showed that 9 of 12(75%) patients achieved good or more recovery. While the second group was observed that 6 of 14(50%) patients achieved good or more recovery. Conclusion : The outcome of the observation, we concludes that the therapeutic rate of the group of adding aqua-acupuncture with hominis placenta was higher than that of basic oriental medicine treatment.

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Effects of Aqua Exercise Program on the improvement of Static Balance in Child with Mental Retardation (수중 운동 프로그램이 정신지체아동의 정적 평형에 미치는 영향)

  • Kim, Eun-Sun
    • The Journal of Korean Physical Therapy
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    • v.16 no.1
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    • pp.208-246
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    • 2004
  • The purpose of this study was to investigate the effect of aqua exercise program on the static balance of child with mental retardation. The subjects were seven male child and three female child with mental retardation(age ranges from 5 to 6). The subjects were practiced with focusing on the aqua exercise program for 8 weeks, from 7, January 2003 to 28, February 2003. The results of this study were as follows : 1. After the exercise program, the balance of double-stance by BPM was significantly reduced of lateral sway number by $12.2\%$(P<.01) with eyes obstruct. 2. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of left leg by $8.5\%$(P<.05) with eyes obstruct. 3. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of right leg by $8.3\%$(P<.05) with eyes obstruct. 4. After the exercise program, the balance of double-stance by BPM was significantly reduced of lateral sway number by $13.2\%$(P<.01) with eyes open. 5. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of left leg by $10.3\%$(P<.05) with eyes open. 6. After the exercise program, the balance of double-stance by BPM was significantly reduced of anterior and posterior sway number of right leg by $10.3\%$(P<.01) with eyes open. As we can see the results of this study, the aqua exercise program improved the static balance of child with mental retardation. Futhermore, it is reasonable program that can improvability of static balance for the children with mental retardation using aqua exercise program. And then it is necessary to develop much better program than now for the children with mental retardation's health and to provide the adequate pool for their aqua exercise.

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Effects of an Aquatic Exercise Program on Body Composition, Blood Components and Physical Fitness in the Elderly Women

  • Lee, Soon-Hee;Yang, In-Suk
    • Journal of the Korea Society of Computer and Information
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    • v.26 no.8
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    • pp.75-81
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    • 2021
  • The purpose of this study was to investigate the effects of aqua exercise program on body composition, blood components, and physical fitness in the elderly women. This study included 23 elderly women. The aqua exercise program was performed for fifty minutes a day, 2 times a week for 12 weeks with moderate-intensity level. Data was analyzed with SPSS using descriptive statistics and the paired t-test. The findings of this study presented that the aqua exercise program showed significant improvements in the body mass index (t=2.42, p=.024), the abdominal circumference (t=4.36, p<.001), and the level of blood glucose (t=3.19, p=.004) and LDL cholesterol (t=3.33, p=.003). These results suggest that aqua exercise is an effective strategy which has positive effects on body composition and blood components among elderly women. It might be possible to promote health condition in elderly women by implementing aqua exercise program which could be considered aging and excercise intensity.

Particulate Organic Carbon (POC) Algorithms for the southwestern part of the East Sea during spring-summer period using MODIS Aqua (MODIS를 이용한 춘.하계 동해 서남부 해역의 해수 중 입자성 유기탄소 함량 추정 알고리즘 개선)

  • Hong, Gi-Hoon;Ahn, Yu-Hwan;Son, Young-Baek;Ryu, Joo-Hyung;Kim, Chang-Joon;Yang, Dong-Beom;Kim, Young-Il;Chung, Chang-Soo
    • Korean Journal of Remote Sensing
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    • v.27 no.2
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    • pp.107-120
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    • 2011
  • Several MODIS AQUA products have been compared with shipboard data to assess the possibility of using remote sensing to estimate particulate organic carbon (POC) concentration in the surface waters of the East Sea. A total of 30 POC profiles obtained in spring and summer seasons of the years of 2006~2010 were compared with remote sensing reflectance at various wavelengths and diffuse attenuation coefficient at 490 nm observed by MODIS AQUA. The algorithm thus established was $POC=266.85^*[R_{rs}(488)/R_{rs}(555)]^{-1.447}$ ($R^2=0.924$) with root mean square error of 20.9 mg $m^{-3}$. Remotely sensed POC contents derived using our algorithm appeared also not to be affected by the presence of non-POC component in suspended particulate matter. Therefore this algorithm could be applied to obtain POC concentration over the East Sea using MODIS Aqua observation.

Effects of Aqua-acupuncture(Cortex Ulmi Pumilae, Ramulus Cinnamomum, Radix Achyranthis, Apitoxin, Calculus Bovis·Fel Ursi·Moschus compound) in Mice with Lipopolysaccharide Induced Arthritis (유백피(楡白皮), 계지(桂枝), 우슬(牛膝), 봉독(蜂毒) 및 우황(牛黃)·웅담(熊膽)·사향(麝香)복잡제제 약침(藥鍼)이 mouse의 LPS유발(誘發) 관절염(關節炎)의 혈액학적(血液學的) 변화(變化)에 미치는 영향(影響))

  • Do, Won-Seok;Kim, Kyung-Ho;Kim, KaP-sUNG
    • Journal of Acupuncture Research
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    • v.18 no.1
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    • pp.157-169
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    • 2001
  • Objective : The purpose of this study is to investigate the effects on WBC counts and each differential of neutrophils, lymphocytes, monocytes in whole blood sample of each experimental Aqua-acupuncture treated mice groups PCortex Ulmi Pumilae(CU), Ramulus Cinnamomum(RC), Radix Achyranthes(RA), Apitoxin(BV), Calculus Bovis Fel Ursi Moschus compound(BUM). Materials & Method : All the BALB/c mice used in this study were bred and maintained in our pathogen-free mouse facility and were 6 weeks of age at the start of the experiment. The experimental model of arthritis was induced by injecting 300${\mu}g$/kg LPS to all mice knee joint. The each of Aqua-acupuncture(Cortex Ulmi Pumilae, Ramulus Cinnamomum, Radix Achyranthes, Apitoxin, Calculus Bovis Fel Ursi Moschus compound) was injected into GB34(陽陵泉) of mice groups every other day for 6 times. And the WBC counts and each differential of neutrophils, lymphocytes, monocytes were measured at the 3rd, 7th and 14th day after LPS injection. Results : 1. The WBC counts were significantly decreased compared with the control(CON) group in every Aqua-acupuncture groups at all days. And at the 14th day, BV & BUM groups were more significantly decreased than RA group. 2. The Neutrophil's ratio was significantty increased compared with the CON group in CU & RC groups at the 3rd day and RC group was more significant than CU group. But at the 7th and 14th day, every Aqua-acupuncture groups were significantly increased compared with the CON group and at the 7th day, RC group was more significant than RA, BV & BUM groups and at the 14th day, RC, BV & BUM groups were more significant than RA group. 3. The Lymphocyte's ratio was significantly decreased compared with the CON group in RC group at the 3rd day. At the 7th day, CU, RC & BV groups were significantly decreased compared with the CON group. At the 14th day, every Aqua-acupuncture groups were significantly decreased compared with the CON group and RC group was more significant than RA group, 4. The Monocyte's ratio was significantly decreased compared with the CON group in every Aqua-acupuncture groups at the 7th day. At the 14th day, BV & BUM groups were significantly decreased compared with the CON group. Conclusion : According to the above results, it was concluded that CU & RC groups were more effective at the early period of this experiment, and at the latter period, BV & BUM groups were more effective than others. RA group was less effctive than others.

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Ultrastructural Study to the Effects of Fel Ursi and Calculus Bovis Aqua-acupuncture (웅담(熊膽).우황(牛黃) 약침(藥鍼)의 효능(效能) 관찰(觀察)을 위한 미세구조적(微細構造的) 연구(硏究))

  • Na, Chang-Su;Kim, Jeong-Sang;Kim, Hui-Cheol;Kim, Byeong-Su;Hwang, U-Jun
    • The Journal of Korean Medicine
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    • v.18 no.1
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    • pp.430-445
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    • 1997
  • In order to know the effects of Calculus $Bovis{\cdot}F디$ Ursi aqua-acupuncture ($C{\cdot}F$ aqua-acupuncture) to the liver damage, we carried out the treatment of $C{\cdot}F$ aqua-acupuncture and injection of Kam-Du-Tang on the liver damaged rat which is induced by aconitine, and then ultrastructural study has been to the liver tissue. The results were as follows: 1. In the hepatic cell of normal group, the nuclear envelope is round and electro-density of nucleoplasm is relatively low, and have one or two large nucleolus. Cell organelle is developed rough endoplasmic reticulum(RER) and many mitochondria, glycogen granules, smooth endoplasmic reticulum(SER) and Golgi apparatus. 2. In 24 hours control group, nuclear envelope is very irregular, RER and most of cell organell is shown that destroyed by aconitine. This is similar to the 48 hours control group. In 72 hours control group, RER is recovered somewhat but cristae of mitochondria is not seen the shape 3.In 24 hours $C{\cdot}F$ aqua-acupuncture group, nuclear envelope is very irregular and cristernae is very dilatable and many mitochondria is dilationed and the cristae is not definite like the control group. In 48 hours $C{\cdot}F$ aqua-acupuncture group, nuclear envelope is relatively round and chromatin is regular. Cristernae of RER and ribosme is somewhat imperfect but is similar the normal group, and the cristae of mitchondria is shown definitely like the normal group. In 72 hours $C{\cdot}F$ aqua-acupuncture group, nuclear envelope is round and cell organell is similar to normal group. 4. In 24 hours Kam-Du-Tang group, nuclear envlope is very irregular and cell organelles are destroyed by the effects of aconitine. In 48 hours Kam-Du-Tang group, nuclear envelope is somewhat irregular but chromatin is relatively regular. RER is seperated regularly through the cytoplasm, but cannot make the structure of lamina, and cistennae is very dilationed. many of glycogen granules is seperated regularly. In 72 hours Kam-Du-Tang group, RER makes the lamina. Mitochondria is a little but inner space is dilationed so the shape of is not definite and a lot of glycogen granules are accumulated in several places. It see the above result, hepatic cell that is damaged by aconitine is effected chiefly by the $C{\cdot}F$ acupuncture and effect of acupuncture is similar to the detoxicated effect of Kam-Du-Tang.

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Effect of the bee venom aqua-acupuncture on the neuronal activities of serotonergic system in brainstem (봉독약침자극(蜂毒藥鍼刺戟)이 뇌간(腦幹) 신경세포(神經細胞)와 Serotonin성(性) 신경세포(神經細胞)의 활성변화(活性變化)에 미치는 영향)

  • Kim, Hye-Nam;Koh, Hyung-Kyun;Park, Dong-Suk;Kang, Sung-Keel;Kim, Yong-Suk;Choi, Yong-Tae
    • Journal of Acupuncture Research
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    • v.17 no.2
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    • pp.119-138
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    • 2000
  • This study was designed to evaluate the effect of the bee venom(BV) aqua-acupuncture on the neuronal activities of serotonergic(5-HT) system in the brainstem. After the BV aqua-acupuncture was applied on Chok-Samni(ST36) and the gluteal part(Blank locus) in rats, the number of Fos immunoreactive neurons was counted by using computerized image analyzing system. Also, the number of colocalization between 5-HT containing neurons Fos immunoreactive neurons were analyzed by using the double immunohistochemical technique. The results of the experiments were summarized as follows : 1. In almost every neucli, the Chok-Samni group and Blank locus group showed more increase in the number of Fos immunoreactive neurons than the control group. Especially, in Arc, DR, LC, RMg, Gi, PAG Rost and PAG LV, the Chok-Samni group showed more significant increase than the control group. Also, in PAG LV Mid and Arc, Chok-Samni group showed more significant increase than the Blank locus group. 2. In DR and PAG LV Mid, Chok-Samni group and the Blank locus group showed more significant increase in the number of colocalization between 5-HT containing neurons and Fos immunoreactive neurons than the control group after the BV aqua- acupuncture. Also, the Chok-Samni group showed more significant increase than the Blank locus group. Consequently, the BV aqua-acupuncture increased more potent the number of Fos immunoreactive neurons and the activity of serotonergic neurons. Furthermore, the BV aqua-acupuncture was more effective on Chok-Samni than Blank locus group. These results indicate that the BV aqua-acupuncture is very effective therapy to control pain. The therapeutic effect of BV aqua-acupunture may associated with the endogenous modulatory system such as serotonin Those data from the study can be applied to establish the effective treatment of the BV for pain control in the clinical field.

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Studies on effect and Safety of various Aqua-acupunctures from Scutellariae Radix (다양(多樣)한 황금약침제제(黃芩藥鍼製劑)의 안전성(安定性) 및 효능(效能)에 관한 연구(硏究))

  • Kim, Ho-Kyoung;Ma, Jin-Yeul;Cheon, Won-Kyung;Yun, Su-Young;Kang, Eun-Jung;Joo, Hye-Jeong;Ko, Byoung-Seob
    • Korean Journal of Oriental Medicine
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    • v.3 no.1
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    • pp.183-197
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    • 1997
  • In order to detect the safety and effect of various aqua-acupunctures from Scutellariae Radix, the modifications of boiling, filtration and dilution were employed for the manufacture of aqua-acupunctures. We injected 0.2cc of aqua-acupunctures into Joksamri (足三里) of rat, repeatedly. We compared subacute toxicity of them with saline group, distilled water(D.W.) group, acupuncture group and control group. The results were summarized as follows: 1. The groups were all healthy and alive, and there was no special abnormality in physical condition and autopsy. And there were not any toxic symptoms in repeating application of aqua-acupunctures to the rat, including changes of body weight, organ weight, haematological examination and serum biochemical test. 2. There was slight change of body weight in acupuncture group : We could see significance after 3 days(p<0.05) and after 7 days(p<0.001) in body weight loss. After 9 days, all tested groups were suppressed in body weight increment. 3. Result of organ weight : In Palkang aqua-acupuncture(D-2 group), saline group and acupuncture group there were some statistical significance. Especially, acupuncture group revealed significant result in liver and spleen than aqua-acupunctures. From this result, we could suggest that the efficacy of acupuncture was preceded herbal medicine. 4. In serum biochemical test, we examined glucose(GLU), triglyceride(TG) and cholesterol(CHOL). In comparison with control group, the diluted 10 times of Hwanggum aqua-aqupuncture$({\times}10\;group)$ was recognized significant decrease of glucose, but the diluted 100 times of Hwanggum aqua-acupuncture$({\times}100\;group)$, D-2 group, saline group were confirmed significant increment. There was not any meaningful change of CHOL in all of tested group, excepting the acupuncture group was exhibited statistically significant decrease(p<0.05). In TG level all tested group except complex injection of standard compound(CPA group) and HG, there were significant value iii statistically. The diluted solution was more significant decrease than Hwanggum aqua-acupuncture(HG). The mutual relationship of components of aqua-acupunture tended to decrease level of TG, regardless of its concentration. In acupunture guoup, we gained some interesting result In meaningful decrease in 7G. 5. Haematological examination showed significant increment of granulocytes(GR) in all tested groups except Hwanggum aqua-acupuncture. And the diluted solutions of HG expressed very high increment of them(p<0.001). The GR and Mean Corpuscular Volume(MCV) of acupuncture group showed statistical significance.

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