• Title/Summary/Keyword: application of M&V

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Effects of GS-386 on the calcium current in rabbit atrial myocytes (GS-386이 단일 심근 세포의 Ca2+ 전류에 미치는 효과)

  • Park, Choon-ok;Chang, Kyeong-jae;Kim, Yang-mi;Haan, Jae-hee;Hong, Seong-geun
    • Korean Journal of Veterinary Research
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    • v.34 no.1
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    • pp.37-47
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    • 1994
  • The effects of the novel compound GS-386 on the calcium current were investigated in rabbit atrial myocytes. The calcium current was recorded during various depolarizations of 200 ms duration from a holding potential of -40 mV using the whole cell patch clamp technique. The calcium current was activated from -30 mV, reached maximum amplitude at +10 mV and almost disappeared at +50 mV. Superfusion of GS-386 led to a reduction of the calcium current amplitude dose-dependently and $ED_{50}$ was $2.5{\times}10^{-7}M$. But the dependence of the calcium current on the membrane potential was not altered by GS-386. The inactivation of the calcium currents showed single exponential curves in both before and after application of GS-386. The inactivation time constants before and after application of GS-386 were almost the same(35 ms and 32.5 ms). The steady-state inactivation curve of the calcium current was not shifted by GS-386. The calcium currents both before and after application of GS-386 recovered completely in 1 sec and the recovery time constants were about 200 ms in both cases. From the above results it is concluded that the novel compound GS-386 has calcium antagonistic property decreasing the calcium current.

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A Study on the Performance of Recycled Cells for application to Residential BESS (주택용 BESS에 적용하기 위한 재활용 셀의 성능에 관한 연구)

  • Phil-Jung Kim;Seong-Soo Yang
    • Journal of IKEEE
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    • v.28 no.1
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    • pp.14-19
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    • 2024
  • To determine the performance of recycled cells for application to residential BESS, cells used over the past 5 years were selected. The basic specifications of the cell used in the test are nominal voltage of 3.7[V], nominal capacity of 2,200[mAh], charging voltage of 4.05[V], continuous discharge current of 1[C](2,200[mA]), continuous charging current of 0.5[C](1,100[mA]). For new cells, the internal resistance was 21.3±1[mΩ], but for recycled cells, the average internal resistance was 25.38[mΩ], an increase of about 19.1[%]. The charge·discharge capacity was approximately 18.9~19.3[%] lower than that of a new cell. Because internal resistance and charge·discharge capacity are closely related to cell aging, cells to be applied to BESS need to use products with an initial internal resistance of 1.5 times or less and a charge·discharge capacity performance of 70[%] or more.

System Design and Performance Analysis of $MnO_2$ Pseudo-capacitor for Digital Communication Applications (디지털 통신 응용을 위한 $MnO_2$, Pseudo-capacitor의 시스템 설계 및 성능평가)

  • Seong W. K.;Hong M. S.;Kim S. W.
    • Journal of the Korean Electrochemical Society
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    • v.3 no.4
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    • pp.241-245
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    • 2000
  • The objective of this work Is to design, fabricate, and characterize pseudo-capacitor using amorphous $MnO_2\;nH_2O$ electrode material. The cyclic voltammogram under 100mV/s scan rate of the material shows the electrochemically stable potential window of 1V and the specific capacitance of 250F/g. The TDMA pulse test result indicates that the TDMA system (2 parallel-pseudo-capacitor systems) has the ohmic voltage drop of 0.22V and the capacitor voltage drop of 0.38V. The total voltage drop of the TDMA system is 0.60V and less than 1V of which value is the maximum voltage drop requirement or the TDMA satellite phone. Also, the TDMA system had the ESR of $55m{\Omega}$ and the capacitance of 105mF. Therefore, it is confirmed that the TDMA system has the application feasibility as load-leveling capacitor for the satellite phone.

Aerodynamic Properties of Granular Agrichemicals (입제 비료 및 농약의 공기역학적 성질)

  • 이성호;이중용;정창주;이채식
    • Journal of Biosystems Engineering
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    • v.23 no.2
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    • pp.105-114
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    • 1998
  • Granule application with a boom has merits of accurate application and high field efficiency. In order to develop a boom granule applicator, aerodynamic properties of agrichemicals should be investigated. This study was accomplished to investigate aerodynamic properties of granules and factors affecting on them. The tested agrichemicals were urea, compound fertilizer (17-21-17), sand and zeolite. Basic physical properties of granules such as true density, sphericity, and arithmetic mean diameter for those materials were analyzed. Regression equations for pickup velocity (v$_{p}$) and saltation velocity (v$_{s}$) were proposed by the data transformation and the multi-regression analysis as follows : (equation omitted) where, 0< s < 1, 0< λ$_{i}$< 3, 35 < D/d$_{p}$ < 350, 1000 $_{p}$/p$_{a}$ < 2500 The range of pickup velocity of fertilizers and other agrichemicals were shown to be 10-16m/s and 9-13m/s, respectively. The saltation velocity of fertilizer and other agrichemicals were 3 m/s and 4 m/s, respectively.y.ively.y.y.

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Numerical analysis results of the cathodic protection for the underground steel pipe by anode installation method

  • Jeong, Jin-A;Choo, Yeon-Gil;Jin, Chung-Kuk;Park, Kyeong-Wan
    • Journal of Advanced Marine Engineering and Technology
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    • v.38 no.10
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    • pp.1212-1216
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    • 2014
  • This study aims to find out the best anode location for buried pipelines. Numerical simulation program known as CATPRO (Elsyca, Belgium) were used for confirming the best location of anodes and the effects of impressed current cathodic protection system. Applied conditions for numerical simulation were similar to on-site environmental conditions for optimal application of cathodic protection system. Used criterion of cathodic protection was NACE SP 0169, which describes that minimum requirement for cathodic protection is -850mV vs. CSE. Various layouts for anodes' installation were applied, which were distance between anodes, anode installation location, and applied current. The areas where cathodic protection potential was lower than -850mV vs. CSE was limited up to 50m from anode installation locations. It was founded numerical analysis obtain cost-effective and efficient cathodic protection methods before design and application the impressed cathodic protection system to on-site environment.

In Vivo Nuclear Imaging of Apoptosis (세포고사의 핵의학영상)

  • Lee, Tae-Sup;Cheon, Gi-Jeong
    • The Korean Journal of Nuclear Medicine
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    • v.38 no.2
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    • pp.190-197
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    • 2004
  • Apoptosis plays a role in the pathophysiology of many kinds of diseases and in the response of treatment. Compared to the necrosis, the apoptosis is a genetically controlled and energy-dependent process which removes the unwanted cells from the body; programmed cell death or cell suicide. During the apoptosis, phosphatidylserine is expressed in the cytoplasmic outer membrane in the early phase. Annexin V, an endogenous human protein (MW=35 kD), has an affinity of about $10^{-9}\;M$ for the phosphatidylserine exposed on the outer membrane of apoptotic cells. Annexin V can be radiolabeled with $^{99m}Tc$ by HYNIC or EC chelators, which can be used as an radiotracer for the in vivo imaging of apoptosis. In this article, we reviewed the apoptosis, radiolabeling of annexin V, and the experimental and clinical data using annexin V imaging.

A 2.5 V 109 dB DR ΔΣ ADC for Audio Application

  • Noh, Gwang-Yol;Ahn, Gil-Cho
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.10 no.4
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    • pp.276-281
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    • 2010
  • A 2.5 V feed-forward second-order deltasigma modulator for audio application is presented. A 9-level quantizer with a tree-structured dynamic element matching (DEM) was employed to improve the linearity by shaping the distortion resulted from the capacitor mismatch of the feedback digital-toanalog converter (DAC). A chopper stabilization technique (CHS) is used to reduce the flicker noise in the first integrator. The prototype delta-sigma analogto-digital converter (ADC) implemented in a 65 nm 1P8M CMOS process occupies 0.747 $mm^2$ and achieves 109.1 dB dynamic range (DR), 85.4 dB signal-to-noise ratio (SNR) in a 24 kHz audio signal bandwidth, while consuming 14.75 mW from a 2.5 V supply.

Susceptometry Application of Portable HTS SQUID-Based System

  • Timofeev, V.P.;Kim, C.G.;Shnyrkov, V.I.
    • Journal of Magnetics
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    • v.3 no.3
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    • pp.86-88
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    • 1998
  • A portable RF HTS SQUID-based susceptometer was used for small size magnetized sample testing in weak DC (up to 200A/m) and AC (up to 4 A/m) magnetic fields. The system resolution for the magnetic moment is of the order of $1.6{\times}10^{-10} A.m^2$. The measured DC susceptibility of a tested sample agrees well with the value obtained by using a commercial liquid helium susceptometer.

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Vibrio vulnificus Cytolysin Forms Anion-selective Pores on the CPAE Cells, a Pulmonary Endothelial Cell Line

  • Choi, Bok-Hee;Park, Byung-Hyun;Kwak, Yong-Geun
    • The Korean Journal of Physiology and Pharmacology
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    • v.8 no.5
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    • pp.259-264
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    • 2004
  • Cytolysin produced by Vibrio vulnificus has been incriminated as one of the important virulence determinants in V. vulnificus infection. Ion selectivity of cytolysin-induced pores was examined in a CPAE cell, a cell line of pulmonary endothelial cell, using inside-out patch clamp techniques. In symmetrical NaCl concentration (140 mM), intracellular or extracellular application of cytolysin formed ion-permeable pores with a single channel conductance of $37.5{\pm}4.0$ pS. The pore currents were consistently maintained after washout of cytolysin. Replacement of $Na^+$ in bath solution with monovalent ions $(K^+,\;Cs^+\;or\;TEA^+)$ or with divalent ions $(Mg^{2+},\;Ca^{2+})$ did not affect the pore currents. When the NaCl concentration in bath solution was lowered from 140 to 60 and 20 mM, the reversal potential shifted from 0 to -11.8 and -28.2 mV, respectively. The relative permeability of the cytolysin pores to anions measured at $-40\;mV\;was\;Cl^-\;=\;NO_2^-\;{\geq}\;Br^-\;=\;I^-\;> \;SCN^-\;>\;acetate^-\;>\;isethionate^-\;>\;ascorbic acid^-\;>\;EDTA^{2-},$ in descending order. The cytolysin-induced pore current was blocked by $CI^-$ channel blockers or nucleotides. These results indicate that V. vulnificus cytolysin forms anion-selective pores in CPAE cells.