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Anti-cancer and Anti-microbial Effect of the Fraction Isolated from Pyrus ussuriensis Leaves (산돌배나무(Pyrus ussuriensis) 잎 분획물의 항암 및 항균활성에 관한 연구)

  • Lee, Chang-Eon;Kim, Young-Hun;Lee, Byung-Guen;Lee, Do-Hyung
    • Journal of Korean Society of Forest Science
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    • v.100 no.2
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    • pp.136-141
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    • 2011
  • This study was conducted to confirm the application as ingredients of cosmetics through an examination of the function for anti-cancer and anti-microbial of the fraction isolated from Pyrus ussuriensis leaves. The dried leaf of P. ussuriensis were extracted with acetone-$H_{2}O$ (6:4, v/v), concentrated and fractionated with the upper layer of acetone on a separatory funnel. Each fraction was freeze dried, then a portion of acetone soluble powder was chromatographed on a Sephadex LH-20 column using a series of aqueous methanol as eluents and also used the MIC-gel using a series of aqueous methanol as developing solvent. The isolated compounds were identified by silica-gel TLC. The growth inhibition activity was measured using the MTT assay by the mouse meltioma (B16F10) cell. The cancer cell growth inhibition rate of fractions isolated from P. ussuriensis leaf was 80%. In anti-microbial activity test, the fraction of P. ussuriensis with 0.25 mg/disc resulted in the clear zone of 1.3 cm and 2 cm for Staphylococcus aureus and S. epidermidis of gram positive bacillus, respectively. In Escherichia coli of gram negative bacillus, the fraction with 0.5 mg/disc resulted in the clear zone of 1.1 cm~1.5 cm each fraction. From these results, we confirmed that acetate fraction of P. ussuriensis has a great potential as a natural ingredients with a anti-cancer and anti-microbial source.

Evaluation of High Flux Combined with Pretreatment Process for Application of Decentralized Water Supply System with Ceramic Membrane (세라믹 분리막의 분산형 용수공급 시스템 적용을 위한 전처리 연계공정의 고플럭스 평가)

  • Kang, Joon-Seok;Park, Seo Gyeong;Lee, Jeong Eun;Kang, So Yeon;Lee, Jeong Jun;Quyen, Vo Thi Kim;Kim, Seongsu;Kim, Han-Seung
    • Journal of Korean Society of Water Science and Technology
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    • v.26 no.6
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    • pp.61-72
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    • 2018
  • In this study, applicability of the decentralized water supply system were investigated by the high flux evaluation using ceramic membrane with combined pretreatment process. A) filtration process increased the transmembrane pressure of 1.4 kPa and 89.5 kPa on 2 and $5m^3/m^2{\cdot}d$ of filtration flux, respectively, the physical backwashing recovery rate were less than 28.6%. The (B) Coag./Floc. - Sedi. combined process with 4 mg / L of A-PAC showed that the transmembrane pressure increased to within 6 kPa, the physical backwashing recovery rate was over 37.9 % higher than (A) Filtration process. (C) Coag./Floc. combined process showed an increase of transmembrane pressure compared with (B) Coag./Floc. - Sedi. combined process, physical backwashing recovery rate was over 84%. As a result of the membrane fouling analysis using the resistance in series model, the combined pretreatment process showed that the cake resistance (Rc) was more than 92% at membrane filtration flux of $2m^3/m^2{\cdot}d$. In the (C) Coag./Floc. combined process, cake resistance(Rc) was over 86% on high flux conditions. The coagulation floc contained in influent was removed by the membrane, and the cake layer formed with the removed floc was identified as reversible fouling resistance which could be recovered by physical backwashing. The decentralized water supply system, which has the limitation of site area and installation space, is considered to could be operation of high flux of ceramic membrane by applying (C) Coag./Floc. combined process without sedimentation process.

A Study on the Application of a Drone-Based 3D Model for Wind Environment Prediction

  • Jang, Yeong Jae;Jo, Hyeon Jeong;Oh, Jae Hong;Lee, Chang No
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.39 no.2
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    • pp.93-101
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    • 2021
  • Recently, with the urban redevelopment and the spread of the planned cities, there is increasing interest in the wind environment, which is related not only to design of buildings and landscaping but also to the comfortability of pedestrians. Numerical analysis for wind environment prediction is underway in many fields, such as dense areas of high-rise building or composition of the apartment complexes, a precisive 3D building model is essentially required in this process. Many studies conducted for wind environment analysis have typically used the method of creating a 3D model by utilizing the building layer included in the GIS (Geographic Information System) data. These data can easily and quickly observe the flow of atmosphere in a wide urban environment, but cannot be suitable for observing precisive flow of atmosphere, and in particular, the effect of a complicated structure of a single building on the flow of atmosphere cannot be calculated. Recently, drone photogrammetry has shown the advantage of being able to automatically perform building modeling based on a large number of images. In this study, we applied photogrammetry technology using a drone to evaluate the flow of atmosphere around two buildings located close to each other. Two 3D models were made into an automatic modeling technique and manual modeling technique. Auto-modeling technique is using an automatically generates a point cloud through photogrammetry and generating models through interpolation, and manual-modeling technique is a manually operated technique that individually generates 3D models based on point clouds. And then the flow of atmosphere for the two models was compared and analyzed. As a result, the wind environment of the two models showed a clear difference, and the model created by auto-modeling showed faster flow of atmosphere than the model created by manual modeling. Also in the case of the 3D mesh generated by auto-modeling showed the limitation of not proceeding an accurate analysis because the precise 3D shape was not reproduced in the closed area such as the porch of the building or the bridge between buildings.

Application of CFD to Design Procedure of Ammonia Injection System in DeNOx Facilities in a Coal-Fired Power Plant (석탄화력 발전소 탈질설비의 암모니아 분사시스템 설계를 위한 CFD 기법 적용에 관한 연구)

  • Kim, Min-Kyu;Kim, Byeong-Seok;Chung, Hee-Taeg
    • Clean Technology
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    • v.27 no.1
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    • pp.61-68
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    • 2021
  • Selective catalytic reduction (SCR) is widely used as a method of removing nitrogen oxide in large-capacity thermal power generation systems. Uniform mixing of the injected ammonia and the inlet flue gas is very important to the performance of the denitrification reduction process in the catalyst bed. In the present study, a computational analysis technique was applied to the ammonia injection system design process of a denitrification facility. The applied model is the denitrification facility of an 800 MW class coal-fired power plant currently in operation. The flow field to be solved ranges from the inlet of the ammonia injection system to the end of the catalyst bed. The flow was analyzed in the two-dimensional domain assuming incompressible. The steady-state turbulent flow was solved with the commercial software named ANSYS-Fluent. The nozzle arrangement gap and injection flow rate in the ammonia injection system were chosen as the design parameters. A total of four (4) cases were simulated and compared. The root mean square of the NH3/NO molar ratio at the inlet of the catalyst layer was chosen as the optimization parameter and the design of the experiment was used as the base of the optimization algorithm. The case where the nozzle pitch and flow rate were adjusted at the same time was the best in terms of flow uniformity.

Assessment of Fluoride Release through Dentin Adhesive in the Alkasite Restorative Material and Giomer (알카자이트 수복재와 자이오머의 상아질 접착제를 투과하는 불소 유리 평가)

  • Kim, Haeni;Park, Howon;Lee, Juhyun;Seo, Hyunwoo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.48 no.4
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    • pp.367-375
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    • 2021
  • This study evaluated the fluoride release of alkasite restorative material (ARM) and giomer penetrating the dentin adhesive layer. Twenty specimens were prepared for each restorative material, and dentin adhesive with uniform thickness was applied to half of them. The prepared specimens were placed in a polyethylene tube containing 2.0 mL of deionized water and deposited in a 37.0℃ water bath for the study duration. The amount of fluoride release was measured on the 1st, 3rd, 7th, 14th, 21st, and 28th days after deposition. The dentin adhesive applied to the ARM and giomer could not completely block the fluoride release; however, it significantly reduced its amount. The cumulative amount of fluoride release of the ARM after 28 days was higher than that of the giomer regardless of the application of dentin adhesive.

Analysis of the Effect of Soil Depth on Landslide Risk Assessment (산사태 조사를 통한 토층심도가 산사태 발생 위험성에 미치는 영향 분석)

  • Kim, Man-Il;Kim, Namgyun;Kwak, Jaehwan;Lee, Seung-Jae
    • The Journal of Engineering Geology
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    • v.32 no.3
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    • pp.327-338
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    • 2022
  • This study aims to empirically and statistically predict soil depths across areas affected by landslides. Using soil depth measurements from a landslide area in Korea, two sets of soil depths are calculated using a Z-model based on terrain elevation and a probabilistic statistical model. Both sets of calculation results are applied to derive landslide risk using the saturated infiltration depth ratio of the soil layer. This facilitates analysis of the infiltration of rainfall into soil layers for a rainfall event. In comparison with the probabilistic statistical model, the Z-model yields soil depths that are closer to measured values in the study area. Landslide risk assessment in the study area based on soil depth predictions from the two models shows that the percentage of first-grade landslide risk assessed using soil depths from the probabilistic statistical model is 2.5 times that calculated using soil depths from the Z-model. This shows that soil depths directly affect landslide risk assessment; therefore, the acquisition and application of local soil depth data are crucial to landslide risk analysis.

A Study on the Application Method of Artificial Injection Test according to the Hydraulic Conductivity of Aquifer (대수층 수리지질특성에 따른 인공함양시험 적용 방법에 관한 연구)

  • Chae, Dong-Seok;Choi, Jin-O;Jeong, Hyeon-Cheol;Kim, Chang-Yong
    • The Journal of Engineering Geology
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    • v.31 no.4
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    • pp.589-601
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    • 2021
  • Artificial recharge technology is a method for solving problems such as groundwater level drop and ground subsidence caused by groundwater withdrawal. This study investigated the applicability of using the hydraulic conductivity of an aquifer to predict injection test results for aquifer restoration. Pumping and injection tests were performed under the same conditions as those for the artificial injection facility located in Icheon, Gyeonggi-do. The hydraulic conductivity of the aquifer, which plays a decisive role in restoring the groundwater level, was derived from the pumping test. A numerical model of a simplified on-site aquifer was constructed, and a transient analysis was applied with the same conditions as the pumping test. The correlation between the measured and the resulting model values is strong (R2 = 0.78). The injection test was performed in a sedimentary layer composed of silt sand and clay sand. From the results of the injection test, an empirical formula was derived using Theim's formula, which is a common well analysis solution to determine the parameters of the aquifer from time-level data. The model values from the empirical formula have a high degree of correlation (R2 = 0.99) with measured values. Under specific conditions, for areas where it is difficult to conduct an injection test, the formula from this study, which relies on the hydraulic conductivity of the aquifer determined through the pumping test, may be used to predict reliable injection rates for groundwater restoration.

Evaluation of Artificial Intelligence Accuracy by Increasing the CNN Hidden Layers: Using Cerebral Hemorrhage CT Data (CNN 은닉층 증가에 따른 인공지능 정확도 평가: 뇌출혈 CT 데이터)

  • Kim, Han-Jun;Kang, Min-Ji;Kim, Eun-Ji;Na, Yong-Hyeon;Park, Jae-Hee;Baek, Su-Eun;Sim, Su-Man;Hong, Joo-Wan
    • Journal of the Korean Society of Radiology
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    • v.16 no.1
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    • pp.1-6
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    • 2022
  • Deep learning is a collection of algorithms that enable learning by summarizing the key contents of large amounts of data; it is being developed to diagnose lesions in the medical imaging field. To evaluate the accuracy of the cerebral hemorrhage diagnosis, we used a convolutional neural network (CNN) to derive the diagnostic accuracy of cerebral parenchyma computed tomography (CT) images and the cerebral parenchyma CT images of areas where cerebral hemorrhages are suspected of having occurred. We compared the accuracy of CNN with different numbers of hidden layers and discovered that CNN with more hidden layers resulted in higher accuracy. The analysis results of the derived CT images used in this study to determine the presence of cerebral hemorrhages are expected to be used as foundation data in studies related to the application of artificial intelligence in the medical imaging industry.

A Study on the Hydraulic Stability of a Multi-Layered Porous Riverbank Revetment Using Castor Oil-Based Biopolymer (피마자유기반 바이오폴리머를 활용한 다층다공성 호안의 수리적 안정성 검토)

  • Sang-Hoon, Lee;Joongu, Kang;Hong-Kyu, Ahn
    • Ecology and Resilient Infrastructure
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    • v.9 no.4
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    • pp.228-236
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    • 2022
  • Riverbank revetments are installed to increase the stability, while preventing scouring, and utilize the rivers; their construction is prioritized to secure dimensional safety that can withstand flooding. Existing revetment technologies employ use of rocks, gabions, and concrete. However, stone and gabions are easily erosion and destroyed by extensive flooding. Though the materials used in concrete technology possess strength and stability, the strong base adversely affects the aquatic ecosystem as components leach and remain in water for a long time. This serves as an environmental and ecological issue as vegetation does not grow on the concrete surface. This study introduces multi-layer porous riverbank revetment technology using biopolymer materials extracted from castor oil. Results obtained from this study suggest that this technology provides greater dimensional stability as compared to existing technologies. Moreover. it does not release toxic substances into the rivers. Multiple experiments conducted to review the application of this technology to diverse river environments confirm that stability is achieved at a flow velocity of 8.0 m/s and maximum tractive force of 67.25 kgf/m2 (659.05 N/m2).

A CFD Study on Aerodynamic Performances by Geometrical Configuration of Guide Vanes in a Denitrification Facility (탈질 설비 내 안내 깃의 기하학적 형상에 따른 공력 성능에 대한 전산 해석적 연구)

  • Chang-Sik, Lee;Min-Kyu, Kim;Byung-Hee, Ahn;Hee-Taeg, Chung
    • Clean Technology
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    • v.28 no.4
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    • pp.316-322
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    • 2022
  • The flow pattern at the inlet of the catalyst layer in a selective catalytic reduction (SCR) system is one of the key parameters influencing the performance of the denitrification process. In the curved diffusing parts between the ammonia injection grids and the catalyst layers, guide vanes are installed to improve flow uniformity. In the present study, a numerical simulation has been performed to investigate the effect of the geometrical configuration of the guide vanes on the aerodynamic characteristics of a denitrification facility. This application has been made to the existing SCR process in a large-scaled coal-fired power plant. The flow domain to be solved covers the whole region of the flow passages from the exit of the ammonia injection gun to the exit of the catalyst layers. ANSYS-Fluent was used to calculate the three-dimensional steady viscous flow fields with the proper turbulence model fitted to the flow characteristics. The root mean square of velocity and the pressure drop inside the flow passages were chosen as the key performance parameters. Four types of guides vanes were proposed to improve the flow quality compared to the current configuration. The numerical results showed that the type 4 configuration was the most effective at improving the aerodynamic performance in terms of flow uniformity and pressure loss.